Photoelectrochemical Approaches for the Functionalization of C-H Bonds

The combination of photocatalysis and electrochemistry has recently emerged as a powerful approach in organic synthesis, enabling the (selective) elaboration of ubiquitous C–H bonds. Photoelectrochemical strategies are driven by open-shell intermediates (radicals and radical-ions), that lead to the desired products with high efficiency thanks to the mild conditions involved. This method offers the possibility to forge a variety of C–C and C–heteroatom bonds, and can be conveniently realized in continuous flow systems as well. Recent advancements include the design of enantioselective functionalization protocols, broadening the applicability of photoelectrochemical approaches towards creating complex organic molecules under sustainable conditions.