The GONO-FOLFOXIRI regimen allow an R0 Surgery in approximately I out of 5 unselected patients with initially unresectable metastatic colorectal cancer, and the long-term survival of resected patients is considerable. Neoadjuvant FOLFOXIRI for 3-6 months is safe and not associated with severe liver injury.
Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin and irinotecan (folfoxiri) followed by radical surgery of metastases
PIETRABISSA, ANDREA;
2009-01-01
Abstract
The GONO-FOLFOXIRI regimen allow an R0 Surgery in approximately I out of 5 unselected patients with initially unresectable metastatic colorectal cancer, and the long-term survival of resected patients is considerable. Neoadjuvant FOLFOXIRI for 3-6 months is safe and not associated with severe liver injury.File in questo prodotto:
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