We measured serum levels of angiogenic molecules in 22 patients with severe autism and 28 controls, aiming to study vascular endothelial growth factor (VEGF) and its soluble receptors sVEGFR-1 and -2 in autism. Results: patients and controls had similar sVEGFR-2 levels, but VEGF levels were lower and sVEGFR-1 higher in patients with autism. Conclusion: the imbalance between VEGF and its receptor sVEGFR-1 may be involved in the pathophysiology of autism.
Serum levels of vascular endothelial growth factor and its receptors in patients with severe autism
EMANUELE, ENZO;ORSI, PAOLO GIUSEPPE;BARALE, FRANCESCO;UCELLI DI NEMI, STEFANIA;POLITI, PIERLUIGI
2010-01-01
Abstract
We measured serum levels of angiogenic molecules in 22 patients with severe autism and 28 controls, aiming to study vascular endothelial growth factor (VEGF) and its soluble receptors sVEGFR-1 and -2 in autism. Results: patients and controls had similar sVEGFR-2 levels, but VEGF levels were lower and sVEGFR-1 higher in patients with autism. Conclusion: the imbalance between VEGF and its receptor sVEGFR-1 may be involved in the pathophysiology of autism.File in questo prodotto:
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