ABSTRACT - Chemical peeling induces a controlled stratum corneum sloughing which results both in varying degrees of desquamation, stimulation and epidermal regeneration, and in consistent derma repair and new collagen formation. The most common side-effect is infiammation. Usually, to reduce or control infiammation, an emollient cream sometimes containing antibiotics or sterolic extracts is applied. However it is khown that natural anti-infiammatory agents exist in bicarbonatecalcium- magnesium thermal water. The aim of our research was to study the anti-infiammatory and antiphlogistic action of bicarbonate-calcium-magnesium thermal water when applied to the skin of an albino rabbit treated with TCA 25%, a potent exfoliant, and then treated with a cold pack ofmineral waters. The degree of infiammation was analysed 24 hours using histological and digitalic evaluation. In both cases, the skin treated with natural water was significantly less infiamed than the untreated skin. However, the skin treated with thermal waters was even less infiamed than both the untreated skin and the skin treated with natural water. These anti-infiammatory effects are probably due to • the buffer activity the bicarbònate-calcium water (Comano Terme) has, and to its rehydrating effect observed in experimental burning.
Antiinflammatory and antiphlogistic action of bicarbonate-calcium-magnesium thermal water when applied to skin treated with TCA 25%.
GREGOTTI, CESARINA;
2009-01-01
Abstract
ABSTRACT - Chemical peeling induces a controlled stratum corneum sloughing which results both in varying degrees of desquamation, stimulation and epidermal regeneration, and in consistent derma repair and new collagen formation. The most common side-effect is infiammation. Usually, to reduce or control infiammation, an emollient cream sometimes containing antibiotics or sterolic extracts is applied. However it is khown that natural anti-infiammatory agents exist in bicarbonatecalcium- magnesium thermal water. The aim of our research was to study the anti-infiammatory and antiphlogistic action of bicarbonate-calcium-magnesium thermal water when applied to the skin of an albino rabbit treated with TCA 25%, a potent exfoliant, and then treated with a cold pack ofmineral waters. The degree of infiammation was analysed 24 hours using histological and digitalic evaluation. In both cases, the skin treated with natural water was significantly less infiamed than the untreated skin. However, the skin treated with thermal waters was even less infiamed than both the untreated skin and the skin treated with natural water. These anti-infiammatory effects are probably due to • the buffer activity the bicarbònate-calcium water (Comano Terme) has, and to its rehydrating effect observed in experimental burning.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
