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A straightforward route for the preparation of 6-substituted naphthols and 6,6'-disubstituted binols (binol=2,2'-dihydroxy-1,1'-binaphthyl) is presented. The synthesis has been accomplished by a one-step procedure starting from 6-bromo derivatives via direct lithiation with n-BuLi, followed by the addition of several electrophiles.

Protecting Group Free Synthesis of 6-Substituted Naphthols and Binols

VERGA, DANIELA;PERCIVALLE, CLAUDIA;DORIA, FILIPPO;PORTA, ALESSIO;FRECCERO, MAURO
2011-01-01

Abstract

A straightforward route for the preparation of 6-substituted naphthols and 6,6'-disubstituted binols (binol=2,2'-dihydroxy-1,1'-binaphthyl) is presented. The synthesis has been accomplished by a one-step procedure starting from 6-bromo derivatives via direct lithiation with n-BuLi, followed by the addition of several electrophiles.
2011
The Organic Chemistry/Polymer Science category includes resources concerned with the related fields of organic chemistry and polymer science. The organic chemistry resources deal with compounds of carbon with the exception of certain simple ones, such as the carbon oxides, carbonates, cyanides and cyanates (see Inorganic & Nuclear Chemistry). This category includes research on synthetic and natural organic compounds that may include other elements, such as hydrogen and oxygen, but also nitrogen, halogens, sulphur and phosphorous. Resources concerned with hydrocarbons, organic compounds containing only the elements carbon and hydrogen, are also included in this category. Examples are the alkanes, alkenes, alkynes and aromatics, such as benzene and naphthalene. Polymer science includes all resources dealing with the study, production and technology of polymers, which are compounds composed of very large molecules made up of repeating molecular units (monomers). Polymers may be natural substances, such as polysaccharides or proteins, or synthetic materials, such as nylon or polyethylene.
JOURNAL OF ORGANIC CHEMISTRY
WOS:000288692000047
2-s2.0-79953206950
Esperti anonimi
Inglese
Internazionale
ELETTRONICO
76
7
2319
2323
5
21384814
International periodic of the American Chemical Society reporting novel important findings of fundamental research in all branches of the theory and practice of organic chemistry.
Organic Synthesis; Protecting groups; Chiral ligands; Binol
5
info:eu-repo/semantics/article
262
Verga, Daniela; Percivalle, Claudia; Doria, Filippo; Porta, Alessio; Freccero, Mauro
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/236690
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