An increasing wealth of evidence suggests an important role for chemokines and their receptors in the pathogenesis of inflammation. In this review, the authors explore the role of chemokines in inflammatory joint diseases, with particular emphasis on rheumatoid arthritis. Recent progress aimed at modulating the chemokine and chemokine receptor system for therapy will also be discussed.

Chemokines in arthritis: key molecules in pathogenesis and potential therapeutic targets

MANZO, ANTONIO;
2006-01-01

Abstract

An increasing wealth of evidence suggests an important role for chemokines and their receptors in the pathogenesis of inflammation. In this review, the authors explore the role of chemokines in inflammatory joint diseases, with particular emphasis on rheumatoid arthritis. Recent progress aimed at modulating the chemokine and chemokine receptor system for therapy will also be discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/368780
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