This book chapter describes preparative methods of chitosan based micro- and nano- particles on the basis of the principles of used techniques. The attention is focused on the following approaches: water-in-oil emulsion and chemical cross-linking, drying techniques (spray-drying, supercritical fluid drying and electrospraying), ionic cross-linking with low molecular weight molecules and macromolecular cross-linking agents, coacervation/precipitation. Finally the same methods are reviewed focusing on the delivery of nucleic acids.
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Titolo: | Manufacture Techniques of Chitosan-Based Microparticles and Nanoparticles for Biopharmaceuticals | |
Autori: | ||
Data di pubblicazione: | 2012 | |
Abstract: | This book chapter describes preparative methods of chitosan based micro- and nano- particles on the basis of the principles of used techniques. The attention is focused on the following approaches: water-in-oil emulsion and chemical cross-linking, drying techniques (spray-drying, supercritical fluid drying and electrospraying), ionic cross-linking with low molecular weight molecules and macromolecular cross-linking agents, coacervation/precipitation. Finally the same methods are reviewed focusing on the delivery of nucleic acids. | |
Handle: | http://hdl.handle.net/11571/398723 | |
ISBN: | 9-78047097832-0 | |
Appare nelle tipologie: | 2.1 Contributo in volume (Capitolo o Saggio) |