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We have obtained a new cell line persistently infected with bovine leukemia virus (BLV). BLV-infected cells can be easily detected by indirect immunofluorescence or immunoperoxidase staining technique. The morphology and number of infected cells seem to be related to serum concentration in culture medium: fetal calf serum (FCS) showed a marked effect on virus growth and virus distribution in cell cultures. All of the commercial lots of FCS tested showed BLV inhibiting activity very similar to that previously described for other viruses.

Bovine leukemia virus inhibiting activity in fetal calf serum.

CEREDA, PAOLO MARTINO;DEBIAGGI, MAURIZIA;PAGANI, LAURA;ROMERO, EGIDIO
1984-01-01

Abstract

We have obtained a new cell line persistently infected with bovine leukemia virus (BLV). BLV-infected cells can be easily detected by indirect immunofluorescence or immunoperoxidase staining technique. The morphology and number of infected cells seem to be related to serum concentration in culture medium: fetal calf serum (FCS) showed a marked effect on virus growth and virus distribution in cell cultures. All of the commercial lots of FCS tested showed BLV inhibiting activity very similar to that previously described for other viruses.
1984
Microbiology covers the biology and biochemistry of microorganisms, bacterial, viral, and parasitic, as well as the medical implications and treatments of the subset of these organisms known to cause disease in humans and/or animals. Biotechnology applications of microorganisms for basic science or clinical use are also covered. Resources that emphasize immune response to pathogens and its modulation by clinical intervention are excluded and are covered in the Immunology category.
MICROBIOLOGICA
sì
Sì, ma tipo non specificato
Italiano
Nazionale
STAMPA
7
251
256
6094986
Animals, Antiviral Agents; physiology, Cattle, Cell Line, Culture Media, Fetal Blood; physiology, Leukemia Virus; Bovine; growth /&/ development, Male, Retroviridae; growth /&/ development
5
info:eu-repo/semantics/article
262
Cereda, PAOLO MARTINO; Debiaggi, Maurizia; P., Mignatti; Pagani, Laura; Romero, Egidio
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/430964
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