We studied the effect of Bacille Calmette-Guerin (BCG) vaccine as an immunomodulator in MS. According to the guidelines for clinical trials in MS, a single crossover, MRI-monitored trial was performed in 14 patients with relapsing-remitting MS. After treatment, MRI activity was significantly reduced. No major adverse effects were reported. Adjuvant therapy with BCG vaccine was safe and merits study in MS.

Use of Bacille Calmette-Guèrin (BCG) in multiple sclerosis.

BASTIANELLO, STEFANO;
1999-01-01

Abstract

We studied the effect of Bacille Calmette-Guerin (BCG) vaccine as an immunomodulator in MS. According to the guidelines for clinical trials in MS, a single crossover, MRI-monitored trial was performed in 14 patients with relapsing-remitting MS. After treatment, MRI activity was significantly reduced. No major adverse effects were reported. Adjuvant therapy with BCG vaccine was safe and merits study in MS.
1999
The Neurology category covers resources concerned with the central and peripheral nervous system including the brain, spinal cord, nerves, and fluids. Coverage includes general and clinical neurology including neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuroradiology, neuropediatrics, neuropathology, and neurobiology. Resources on cerebrovascular diseases, movement and spinal disorders, pain, dementia, headache, aphasiology, brain injury, paraplegia, stroke, and acupuncture are also included.
Sì, ma tipo non specificato
Inglese
Internazionale
STAMPA
53
1588
1589
Adjuvants; Immunologic; therapeutic use, Adult, BCG Vaccine; therapeutic use, Brain; pathology, Cross-Over Studies, Female, Humans, Magnetic Resonance Imaging, Male, Multiple Sclerosis; diagnosis/drug therapy/physiopathology, Recurrence, Treatment Outcome
11
info:eu-repo/semantics/article
262
G., Ristori; M. G., Buzzi; U., Sabatini; E., Giugni; Bastianello, Stefano; F., Viselli; C., Buttinelli; S., Ruggieri; C., Colonnese; C., Pozzilli; M.,...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/441831
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