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A number of assays have been described for aminoglycoside-modifying enzymes; the aim of our investigation was to check the validity of polarized immunofluorescence assay for aminoglycoside enzymes. We have studied three enzymes encoded by R-factors from clinical isolates of Enterobacteriaceae conferring various patterns of aminoglycoside-resistance. The assay resulted valid: this is a simple, rapid and sensitive method.

[Prospective use of immunofluorescence polarization in the study of enzymes modifying aminoglycosides].

PAGANI, LAURA;PERDUCA, MARGHERITA;ROMERO, EGIDIO
1985-01-01

Abstract

A number of assays have been described for aminoglycoside-modifying enzymes; the aim of our investigation was to check the validity of polarized immunofluorescence assay for aminoglycoside enzymes. We have studied three enzymes encoded by R-factors from clinical isolates of Enterobacteriaceae conferring various patterns of aminoglycoside-resistance. The assay resulted valid: this is a simple, rapid and sensitive method.
1985
Microbiology covers the biology and biochemistry of microorganisms, bacterial, viral, and parasitic, as well as the medical implications and treatments of the subset of these organisms known to cause disease in humans and/or animals. Biotechnology applications of microorganisms for basic science or clinical use are also covered. Resources that emphasize immune response to pathogens and its modulation by clinical intervention are excluded and are covered in the Immunology category.
BOLLETTINO DELL'ISTITUTO SIEROTERAPICO MILANESE
sì
A1985ASS7100006
Sì, ma tipo non specificato
Italiano
Nazionale
STAMPA
64
285
288
3907665
Aminoglycosides; metabolism, Anti-Bacterial Agents; metabolism, Drug Resistance; Microbial, Enterobacteriaceae; drug effects/enzymology, Fluorescence Polarization, Immunologic Techniques, R Factors
5
info:eu-repo/semantics/article
262
Pagani, Laura; Perduca, Margherita; V., Mills; E., Giacobone; Romero, Egidio
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/444280
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