2-O-beta-D-Galactosylglycerol 1 was submitted to acylation using Pseudomonas cepacia or Candida antarctica lipases as catalysts and 2,2,2-trifluoroethyl esters of butanoic, hexanoic, octanoic or decanoic acid as acyl carriers. Taking advantage of the high diastereoselectivity and regioselectivity of the two enzymes, the 1-O-, 3-O-, 6'-O-acyl and the 1,6'-di-O-acylderivatives of 1 were obtained pure or in an appreciably enriched form. (C) 1998 Elsevier Science Ltd. All rights reserved.

Bioctive glycoglycerolipid analogues: an expeditious enzymatic approach to mono- and diesters of 2-O-beta-D-galactoglycerol

TOMA, LUCIO
1998-01-01

Abstract

2-O-beta-D-Galactosylglycerol 1 was submitted to acylation using Pseudomonas cepacia or Candida antarctica lipases as catalysts and 2,2,2-trifluoroethyl esters of butanoic, hexanoic, octanoic or decanoic acid as acyl carriers. Taking advantage of the high diastereoselectivity and regioselectivity of the two enzymes, the 1-O-, 3-O-, 6'-O-acyl and the 1,6'-di-O-acylderivatives of 1 were obtained pure or in an appreciably enriched form. (C) 1998 Elsevier Science Ltd. All rights reserved.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/455825
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