Some 7-piperazinoquinolones undergo smooth cathodic defluorination in aqueous buffer (pH7.2) at -1.35V vs Ag/AgCl via an ECE mechanism; a 6-fluoro derivative is reduced, a 6,8-difluoro analogue is selectively reduced at position 8.

First electrochemical defluorination in heterocyclic chemistry. Mild cathodic reduction of some fluoroquinolones

PROFUMO, ANTONELLA;FASANI, ELISA;ALBINI, ANGELO
1999

Abstract

Some 7-piperazinoquinolones undergo smooth cathodic defluorination in aqueous buffer (pH7.2) at -1.35V vs Ag/AgCl via an ECE mechanism; a 6-fluoro derivative is reduced, a 6,8-difluoro analogue is selectively reduced at position 8.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11571/456292
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact