The pharmacokinetics and bioavailability of suckable tablets and granules of N-acetylcysteine (NAC) have been compared after oral administration of 400 mg doses to 10 healthy volunteers. The oral bioavailability of the NAC tablets was 103%. In a multiple dosing study of the same tablets in the same subjects, a high maintenance plasma level of NAC was revealed.

Bioavailability of oral N-acetylcysteine as suckable tables in man.

DE BERNARDI DI VALSERRA, MARIO;FELETTI, FAUSTO;
1989-01-01

Abstract

The pharmacokinetics and bioavailability of suckable tablets and granules of N-acetylcysteine (NAC) have been compared after oral administration of 400 mg doses to 10 healthy volunteers. The oral bioavailability of the NAC tablets was 103%. In a multiple dosing study of the same tablets in the same subjects, a high maintenance plasma level of NAC was revealed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/457222
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