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A carrot cell line (WCA1) resistant to Mtx has been isolated and partially characterizaed. The IC50-Mtx is about thirty times higher in the resistant than in the parental line and the rate of uptake of Mtx is decreased 14 times. In addition the specific activity of DHFR is about three times higher in the resistant line as compared to the parent

Isolation and characterization of a carrot cell line resistant to methotrexate.

CELLA, RINO;
1984-01-01

Abstract

A carrot cell line (WCA1) resistant to Mtx has been isolated and partially characterizaed. The IC50-Mtx is about thirty times higher in the resistant than in the parental line and the rate of uptake of Mtx is decreased 14 times. In addition the specific activity of DHFR is about three times higher in the resistant line as compared to the parent
1984
The Plant Sciences category covers many areas, including broad botany resources, regional botany, mycology, bryology, plant physiology, forestry, weed science, plant pathology, economic botany, plant nutrition, photosynthesis research, experimental botany, and plant cell research.
JOURNAL OF EXPERIMENTAL BOTANY
sì
Sì, ma tipo non specificato
Inglese
Internazionale
STAMPA
35
158
1390
1397
8
Methotreaxte resistance; dihydrofolate reductase; methterxate uptake; plant cell suspension culture; Daucus carota
5
info:eu-repo/semantics/article
262
Cella, Rino; Albani, D; Biasini, Mg; Carbonera, D; Parisi B., 1390 1397
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/461501
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