Curcumin is a potent inhibitor of SULT1A1 in human liver, duodenum, colon, kidney and lung. The IC50 of curcumin for SULT1A1 varied 4.9-fold in human liver. The comparison of the present data with those of the literature revealed that the IC50 of curcumin in the liver and extrahepatic tissues is one order of magnitude lower that the peak serum concentration of curcumin after therapeutic doses of 4 g to humans
Curcumin is a potent inhibitor of phenol sulfotransferase (SULT1A1) in human liver and extrahepatic tissues.
PIETRABISSA, ANDREA;
2003-01-01
Abstract
Curcumin is a potent inhibitor of SULT1A1 in human liver, duodenum, colon, kidney and lung. The IC50 of curcumin for SULT1A1 varied 4.9-fold in human liver. The comparison of the present data with those of the literature revealed that the IC50 of curcumin in the liver and extrahepatic tissues is one order of magnitude lower that the peak serum concentration of curcumin after therapeutic doses of 4 g to humansFile in questo prodotto:
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