CINECA IRIS Institutional Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishA purine nucleoside phosphorylase from Aeromonas hydrophila was cloned, expressed in Escherichia coli and purified. The enzyme showed a good stability and a broad substrate specificity towards modified purine ribonucleosides. The enzyme was used for the synthesis of purine nucleosides structurally related to compounds of biological interest via a “one pot, one enzyme” transglycosylation reaction using 7-methyl guanosine iodide as the sugar donor and 6-substituted purines as acceptor.
Scheda prodotto non validato
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
| Titolo: | Sintesi chemoenzimatica di nucleosidi |
| Autori: | |
| Data di pubblicazione: | 2012 |
| Rivista: | |
| Abstract: | A purine nucleoside phosphorylase from Aeromonas hydrophila was cloned, expressed in Escherichia coli and purified. The enzyme showed a good stability and a broad substrate specificity towards modified purine ribonucleosides. The enzyme was used for the synthesis of purine nucleosides structurally related to compounds of biological interest via a “one pot, one enzyme” transglycosylation reaction using 7-methyl guanosine iodide as the sugar donor and 6-substituted purines as acceptor. |
| Handle: | http://hdl.handle.net/11571/582538 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
Copyright © 2021