BCORL1 mutations do not seem to be commonly associated with leukemic transformation of MPN, further substantiating the different molecular profile compared with denovo leukemias. Although the small number of cases does not allow us to exclude that BCORL1 mutations can be found also in post-MPN AML, their occurrence is, at least, very infrequent and their detection does not appear to deserve clinical relevance.

Mutational analysis of BCORL1 in the leukemic transformation of chronic myeloproliferative neoplasms.

RUMI, ELISA;CAZZOLA, MARIO;
2014-01-01

Abstract

BCORL1 mutations do not seem to be commonly associated with leukemic transformation of MPN, further substantiating the different molecular profile compared with denovo leukemias. Although the small number of cases does not allow us to exclude that BCORL1 mutations can be found also in post-MPN AML, their occurrence is, at least, very infrequent and their detection does not appear to deserve clinical relevance.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/743619
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