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Bioinformatics tools have been recently applied to study the differentiation of the mammalian oocyte during folliculogenesis. In this review, we will summarize our knowledge of 1) the use of biological databases for the extraction of relevant information, 2) bioinformatics methods for knowledge extraction and representation, 3) the application of these methods to the study of mammalian oocyte differentiation and 4) state-of the-art prediction approaches for the assessment and estimation of the cell differentiation status.

Knowledge-based bioinformatics for the study of mammalian oocytes

SACCHI, LUCIA;GARAGNA, SILVIA;Zuccotti M.;BELLAZZI, RICCARDO
2012-01-01

Abstract

Bioinformatics tools have been recently applied to study the differentiation of the mammalian oocyte during folliculogenesis. In this review, we will summarize our knowledge of 1) the use of biological databases for the extraction of relevant information, 2) bioinformatics methods for knowledge extraction and representation, 3) the application of these methods to the study of mammalian oocyte differentiation and 4) state-of the-art prediction approaches for the assessment and estimation of the cell differentiation status.
2012
Computer Science & Engineering includes resources on computer hardware and architecture, computer software, software engineering and design, computer graphics, programming languages, theoretical computing, computing methodologies, broad computing topics, and interdisciplinary computer applications.
Medical Research, General Topics covers a wide array of topics in medical and biomedical research, with a specific emphasis on human disease, human tissues, and all levels of research into the pathogenesis of clinically significant conditions. Specific medical fields that are characterized by the inclusion of material from several other specializations are also covered here; these include general and internal medicine, tropical medicine, pediatrics, gerontology, epidemiology, and public health. Resources dealing with specific clinical interventions are excluded and are placed in the Medical Research: Diagnosis & Treatment category. Resources that emphasize the specific disease types, or specific systems affected are also excluded and are categorized according to the pathogen or system pathophysiology.
Molecular Biology & Genetics considers all aspects of basic and applied genetics, including molecular genetics, prokaryotic and eukaryotic gene expression, mechanisms of mutagenesis, structure, function and regulation of genetic material. Also included are resources concerned with clinical genetics, patterns of inheritance, genetic cause, and screening and treatment of disease. Resources dealing specifically with developmentally regulated gene expression, or with signal transduction pathways that modulate gene expression at the cellular level are excluded and are covered in the Cell and Developmental Biology category.
THE INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
sì
WOS:000208895100012
2-s2.0-84873736865
Esperti anonimi
Inglese
Internazionale
ELETTRONICO
56
859
866
8
knowledge-based methods; bioinformatics; developmental biology; folliculogenensis
sì
7
info:eu-repo/semantics/article
262
Mulas, F.; Sacchi, Lucia; Zagar, L.; Garagna, Silvia; Zuccotti, M.; Zupan, B.; Bellazzi, Riccardo
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/813834
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