The findings of this study indicate that the MYD88 (L265P) mutation is an independent predictor of progression of IgM-MGUS to WM or to other LPD, irrespective of the concentration of the M protein. The presence of both MYD88 mutation and a serum M protein >1.5 g/dL at diagnosis identifies a subset of IgM-MGUS patients at high risk of progression.

MYD88 (L265P) mutation is an independent risk factor for progression in patients with IgM monoclonal gammopathy of undetermined significance

ARCAINI, LUCA;PAULLI, MARCO;CAZZOLA, MARIO
2013

Abstract

The findings of this study indicate that the MYD88 (L265P) mutation is an independent predictor of progression of IgM-MGUS to WM or to other LPD, irrespective of the concentration of the M protein. The presence of both MYD88 mutation and a serum M protein >1.5 g/dL at diagnosis identifies a subset of IgM-MGUS patients at high risk of progression.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11571/849459
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