It has long been held that embryologic fusion planes might be related with the sites of onset and spread paths of basal cell carcinomas (BCCs) thus supposing an embryologic role for the pathogenesis of such a peculiar malignancy.1–3 A recent clinical study demonstrated that BCCs were more than 4 times more likely to occur on the embryonic fusion planes than on other regions of the midface.4 In our study, we correlated the distribution of all BCCs of the head and neck admitted at our unit over the last 5 years with the typical sites of craniofacial clefts and of congenital clefts, fistulas, and cysts of the neck.
Sites of Basal cell carcinomas and head and neck congenital clefts: topographic correlation
NICOLETTI, GIOVANNI;BRENTA, FEDERICA;FAGA, ANGELA
2014-01-01
Abstract
It has long been held that embryologic fusion planes might be related with the sites of onset and spread paths of basal cell carcinomas (BCCs) thus supposing an embryologic role for the pathogenesis of such a peculiar malignancy.1–3 A recent clinical study demonstrated that BCCs were more than 4 times more likely to occur on the embryonic fusion planes than on other regions of the midface.4 In our study, we correlated the distribution of all BCCs of the head and neck admitted at our unit over the last 5 years with the typical sites of craniofacial clefts and of congenital clefts, fistulas, and cysts of the neck.File in questo prodotto:
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