ANDANTE Multidisciplinary evaluation of the cancer risk from neutrons relative to photons using stem cells and the induction of second malignant neoplasms following paediatric radiation therapy - Better appraising the risk from exposure to low doses of neutron radiation

Despite decades of research, there is still considerable uncertainty about what risks neutron radiation poses to humans. The ANDANTE project will take a multi-disciplinary approach to investigating the relative risk of induction of cancer from exposure to a range of different energy neutrons compared to photons, the relative biological effectiveness (RBE). A model for predicting risks will be developed using animal and human stem cells and tested in a prospective epidemiological study of second cancers caused following paediatric proton therapy.