VALENTINI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 3.056
AS - Asia 2.202
EU - Europa 2.156
SA - Sud America 222
AF - Africa 26
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.665
Nazione #
US - Stati Uniti d'America 2.989
CN - Cina 1.359
IE - Irlanda 520
SG - Singapore 399
UA - Ucraina 334
FI - Finlandia 291
DE - Germania 250
HK - Hong Kong 232
RU - Federazione Russa 221
BR - Brasile 175
SE - Svezia 143
IT - Italia 115
GB - Regno Unito 109
VN - Vietnam 80
FR - Francia 65
CA - Canada 43
BE - Belgio 30
IN - India 28
AR - Argentina 21
NL - Olanda 19
JP - Giappone 16
MX - Messico 16
BD - Bangladesh 14
PL - Polonia 12
ES - Italia 11
TR - Turchia 11
IQ - Iraq 9
ID - Indonesia 8
IR - Iran 8
SA - Arabia Saudita 8
ZA - Sudafrica 8
CZ - Repubblica Ceca 7
LT - Lituania 6
PE - Perù 6
CL - Cile 5
MA - Marocco 5
PK - Pakistan 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
LV - Lettonia 4
MU - Mauritius 4
RO - Romania 4
UZ - Uzbekistan 4
VE - Venezuela 4
EC - Ecuador 3
PY - Paraguay 3
AZ - Azerbaigian 2
BB - Barbados 2
BO - Bolivia 2
EG - Egitto 2
GE - Georgia 2
GR - Grecia 2
JM - Giamaica 2
LB - Libano 2
MD - Moldavia 2
NP - Nepal 2
PA - Panama 2
SN - Senegal 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
AU - Australia 1
BH - Bahrain 1
BS - Bahamas 1
BY - Bielorussia 1
CH - Svizzera 1
CO - Colombia 1
CR - Costa Rica 1
CV - Capo Verde 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
GM - Gambi 1
HU - Ungheria 1
IL - Israele 1
JO - Giordania 1
KG - Kirghizistan 1
KR - Corea 1
KZ - Kazakistan 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 7.665
Città #
Dublin 519
Chandler 505
Jacksonville 372
Beijing 283
Nanjing 270
Hong Kong 230
Ashburn 222
Singapore 188
Dallas 166
Ann Arbor 152
Boardman 146
Nanchang 131
Helsinki 106
Wilmington 104
Los Angeles 96
Lawrence 85
Medford 85
Princeton 85
New York 83
Shenyang 76
Hebei 70
Changsha 69
Munich 67
Jiaxing 62
Hangzhou 61
Tianjin 60
Shanghai 49
Woodbridge 39
Buffalo 38
Milan 38
Moscow 35
Ho Chi Minh City 32
Brussels 30
São Paulo 25
Verona 25
Turku 21
Redondo Beach 17
Denver 16
Hanoi 16
Norwalk 15
Tokyo 15
Dearborn 14
Falls Church 14
Pavia 14
Boston 13
Chicago 13
Toronto 13
Montreal 12
Auburn Hills 11
Jinan 11
Brooklyn 10
Phoenix 10
The Dalles 10
Warsaw 10
Atlanta 9
Des Moines 9
Fairfield 9
London 9
Seattle 9
Tappahannock 9
Chennai 8
Frankfurt am Main 8
Piscataway 8
Stockholm 8
Houston 7
Kunming 7
Taizhou 7
Ankara 6
Mexico City 6
Ningbo 6
Rio de Janeiro 6
San Francisco 6
Baghdad 5
Buenos Aires 5
Columbus 5
Curitiba 5
Da Nang 5
Falkenstein 5
Fuzhou 5
Johannesburg 5
Kiel 5
Lima 5
Roubaix 5
Santa Clara 5
Brno 4
Calgary 4
Changchun 4
Cleveland 4
Guangzhou 4
Guarulhos 4
Haiphong 4
Manchester 4
Nuremberg 4
Orem 4
Poplar 4
Sacramento 4
San Genesio ed Uniti 4
San Jose 4
Tashkent 4
Vienna 4
Totale 5.120
Nome #
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 134
Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells 129
Divergent biding sites in pyruvate kinase I and II from Escherichia coli. 128
Letter to the editor regarding Shibayama et al.: Biochemical and pathophysiological characterization of Helicobacter pylori asparaginase. 127
Primary structure of three peptides at the catalytic and allosteric sites of the fructose 1,6-bisphosphate-activated pyruvate kinase from Escherichia coli 124
Aberrant Doppel Protein Expression in Human Astrocytic Tumors 119
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants 117
The prion-like doppel protein is soluble in astrocytic tumor 116
Expanding targets for a metabolic therapy of cancer: L-asparaginase 116
Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 115
Phosphoglycerate Kinase Deficiency: Characterization of the Wild-Type Enzyme and Three Pathological Variants Generated from C.140T>a, C.491A>T and C.959G>a Mutations 113
Generation of Mutants of Helicobacter pylori L-Asparaginase 113
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli: ligands promoted conformational changes 112
Molecular and cellular insights into the aberrant expression of the prion protein-like gene doppel in astrocytic tumors 111
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 110
Influence of fibronectine on the fibrillogenesis of type I and type III collagen 109
A simple procedure for the purification of neutral salt soluble type I collagene from skin. 109
Ectopic expression of the prion-like protein doppel in human astrocytoma cells 107
Expanding Targets for a Metabolic Therapy of Cancer: L- Asparaginase 106
Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene. 106
The prion protein-like gene Doppel is aberrantly expressed in astrocytic tumors 105
Affinity labelling of the catalytic and allosteric ATP binding sites on pyruvate kinase type I from Escherichia coli. 103
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 103
An essential lysine in the substrate-binding of ornithine carbamoyl transferase 102
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 102
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 102
Biochemistry of Lipolytic Enzymes Secreted by Penicillium solitum and Cladosporium cladosporioides 102
Bacterial pyruvate kinases have a shorter N-terminal domain 102
AMP- and fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. 101
A comparative study on liver ornithine carbamoyl transferase from a marine mammal Stenella and a elasmobranch Sphyrna zygaena. 101
Two forms of pyruvate kinase in Escherichia coli. A comparison of chemical and molecular properties 100
Pyruvate kinase deficiency: Biochemical characterization of two mutations causing inability of the enzyme to properly bind substrates 100
Helicobacter pylori L-asparaginase: from Gene to Diagnostic Tool 100
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 100
Molecular cloning and characterisation of Helicobacter pylori L-asparaginase 99
Helicobacter pylori: from gene to Diagnostic Tool 99
Biochemical signatures of doppel (Dpl) protein in human glioblastoma to support prediction in tumor malignancy 98
Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells 96
A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency. 96
Reactivity of the fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli with pyridoxal 5’-phosphate 94
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. Natures of bonds involved in the allosteric mecchanism. 93
SELECTION OF MICROFUNGI WITH HIGH LIPOLYTIC ACTIVITYAND THEIR LIPASE CHARACTERIZATION 93
Premio Ricercatissimi 2008 92
Molecular Insights on Pathogenic Effects of MutationsCausing Phosphoglycerate Kinase Deficiency 91
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 91
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization. 91
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 88
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 87
The allosteric regulation of pyruvate kinase. 86
Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia 86
Erythrocyte Adenylate Kinase Deficiency: First In-Depth Biochemical Characterization of the Y164C Mutant Enzyme Causing Hemolytic Anemia 84
Pyrimidine 5' Nucleotidase Deficiency: Clinical and Molecular Characterization of Two New Italian Patients 84
Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase. 83
Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5-Nucleotidase Causing Hereditary Hemolytic Anemia. 83
Purification and molecular properties of the AMP-activated pyruvate kinase from Escherichia coli. 82
EXPRESSION AND CHARACTERIZATION OF THE BOVINE PRION DOPPEL 82
Inosine monophosphate dehydrogenase activity after mycophenolate mofetil in renal transplant patients receiving different immunosupressive combined therapy and stable after at least three months' administration. 82
Molecular basis of pyrimidine 5'-nucleotidase deficiency caused by 3 newly identified missense mutations (c.187T>C, c.469G>C and c.740T>C) and a tabulation of known mutations 82
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 80
PYRUVATE KINASE DEFICIENCY: MOLECULAR AND FUNCTIONAL CHARACTERISATION OF A LETHAL VARIANT 79
Red cell pyruvate kinase deficiency: molecular and clinical aspects 77
Hereditary pyrimidine 5'-nucleotidase deficiency: from genetics to clinical manifestations. 75
Pyruvate kinase deficiency : The genotype-phenotype association 75
Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency 75
Molecular and functional characterization of a lethal variant of pyruvate kinase deficiency 74
The allosteric regulation of pyruvate kinase 74
Pyrimidine 5'-nucleotidase activities detected in real samples by means of micellar electrokinetic chromatography. 73
Functional and structural characterization of ovine ornithine transcarbamoylase 73
Hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency: a biochemical, genetic and clinical overview 72
Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase 72
Red cell pyruvate kinase deficiency: 17 new mutations of the PK-LR gene 71
Two new mutations of the P5'N-1 gene found in Italian patients with hereditary hemolytic anemia: the molecular basis of the red cell enzyme disorder. 70
Investigating the Molecular Bases of the Phosphoglycerate Kinase Deficiency: Characterization ofG158V, R206P, V266M and D285V Pathological Variants. 70
Molecular Basis of Hemolytic Anemia: First Biochemical Characterization of Wild-Type and N190S Mutant Human Erythrocyte Pyrimidine 5'-Nucleotidase. 70
PHOSPHOGLYCERATE KINASE DEFICIENCY: FUNCTIONAL PROPERTIES OF THE L89P, K191DEL, C316R AND A354P PATHOLOGICAL VARIANTS 69
L-ASPARAGINASE FROM HELICOBACTER PYLORI 68
Functional analysis of pyrimidine 5'-nucleotidase mutants causing nonspherocytic hemolytic anemia 67
Protein Stability, Folding and Misfolding in Human PGK1 Deficiency 67
Functional Analysis of Two Mutants of Pyrimidine 5’ Nucleotidase Causing Nonspherocytic Hemolytic Anemia 64
Molecular Cloning and Characterisation of Helicobacter Pylori L-Asparaginase: A Cytotoxic Factor with Potential Biomedical Applications 63
The interplay between protein stability and folding co-operativity in loss-of-function genetic disease: The case of human PGK1 deficiency. 62
Monitoring Inosine monophosphate dehydrogenase (IMPDH) in kidney transplant recipients 56
Helicobacter pylori L-asparaginase: A promising chemotherapeutic agent 55
Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy 48
Protein stability, folding and misfolding in human PGK1 deficiency 26
Totale 7.711
Categoria #
all - tutte 30.937
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.937


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021389 0 0 0 0 0 79 8 87 19 91 86 19
2021/2022450 6 7 9 6 26 17 15 32 32 20 51 229
2022/20231.411 124 122 9 128 157 155 1 64 594 8 32 17
2023/2024516 121 70 6 43 50 141 7 32 0 12 20 14
2024/20251.228 28 97 45 44 32 52 41 73 322 23 179 292
2025/20261.535 234 197 300 370 357 77 0 0 0 0 0 0
Totale 7.711