VALENTINI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 2.437
EU - Europa 2.020
AS - Asia 1.529
SA - Sud America 102
AF - Africa 9
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.100
Nazione #
US - Stati Uniti d'America 2.409
CN - Cina 1.098
IE - Irlanda 520
UA - Ucraina 330
FI - Finlandia 282
RU - Federazione Russa 216
DE - Germania 214
HK - Hong Kong 210
SG - Singapore 174
SE - Svezia 136
IT - Italia 111
GB - Regno Unito 90
BR - Brasile 84
FR - Francia 45
BE - Belgio 30
CA - Canada 18
NL - Olanda 17
AR - Argentina 9
IN - India 9
CZ - Repubblica Ceca 7
JP - Giappone 7
IR - Iran 6
MX - Messico 5
AT - Austria 4
MU - Mauritius 4
LV - Lettonia 3
PK - Pakistan 3
SA - Arabia Saudita 3
TR - Turchia 3
BB - Barbados 2
BD - Bangladesh 2
CL - Cile 2
EC - Ecuador 2
EG - Egitto 2
ES - Italia 2
GR - Grecia 2
IQ - Iraq 2
JM - Giamaica 2
MA - Marocco 2
MD - Moldavia 2
PE - Perù 2
RO - Romania 2
VN - Vietnam 2
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BO - Bolivia 1
BY - Bielorussia 1
CH - Svizzera 1
DK - Danimarca 1
EU - Europa 1
GE - Georgia 1
ID - Indonesia 1
IL - Israele 1
JO - Giordania 1
KZ - Kazakistan 1
LB - Libano 1
LT - Lituania 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
PL - Polonia 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 6.100
Città #
Dublin 519
Chandler 505
Jacksonville 372
Nanjing 270
Hong Kong 208
Beijing 198
Ann Arbor 152
Boardman 146
Ashburn 131
Nanchang 130
Helsinki 104
Wilmington 104
Singapore 94
Lawrence 85
Medford 85
Princeton 85
Shenyang 75
New York 71
Hebei 70
Changsha 68
Jiaxing 61
Hangzhou 59
Tianjin 58
Shanghai 45
Woodbridge 39
Milan 38
Munich 38
Moscow 34
Brussels 30
Los Angeles 27
Verona 25
Norwalk 15
Dearborn 14
Falls Church 14
Pavia 14
Turku 14
Auburn Hills 11
The Dalles 10
Toronto 10
Chicago 9
Des Moines 9
Fairfield 9
São Paulo 9
Tappahannock 9
Jinan 8
Piscataway 8
Seattle 8
Kunming 7
Taizhou 7
Brooklyn 6
Dallas 6
London 6
Ningbo 6
San Francisco 6
Tokyo 6
Falkenstein 5
Kiel 5
Boston 4
Brno 4
Buenos Aires 4
Mexico City 4
Nuremberg 4
Sacramento 4
San Genesio ed Uniti 4
Vienna 4
Zhengzhou 4
Andover 3
Birmingham 3
Contagem 3
Curitiba 3
Fuzhou 3
Groningen 3
Houston 3
Islamabad 3
Riyadh 3
Zanjan 3
Bridgetown 2
Carapicuíba 2
Castenaso 2
Changchun 2
Chisinau 2
Cincinnati 2
Costa Mesa 2
Duque de Caxias 2
Düsseldorf 2
Edinburgh 2
Haikou 2
Kingston 2
Leawood 2
Madrid 2
Monmouth Junction 2
Newark 2
Olomouc 2
Paderno Dugnano 2
Quito 2
Riga 2
Rio de Janeiro 2
San Jose 2
Santa Clara 2
Viamão 2
Totale 4.271
Nome #
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 106
The prion-like doppel protein is soluble in astrocytic tumor 101
Generation of Mutants of Helicobacter pylori L-Asparaginase 101
Expanding targets for a metabolic therapy of cancer: L-asparaginase 100
Primary structure of three peptides at the catalytic and allosteric sites of the fructose 1,6-bisphosphate-activated pyruvate kinase from Escherichia coli 99
Aberrant Doppel Protein Expression in Human Astrocytic Tumors 97
Divergent biding sites in pyruvate kinase I and II from Escherichia coli. 97
Phosphoglycerate Kinase Deficiency: Characterization of the Wild-Type Enzyme and Three Pathological Variants Generated from C.140T>a, C.491A>T and C.959G>a Mutations 96
Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells 95
Letter to the editor regarding Shibayama et al.: Biochemical and pathophysiological characterization of Helicobacter pylori asparaginase. 95
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants 94
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli: ligands promoted conformational changes 92
Ectopic expression of the prion-like protein doppel in human astrocytoma cells 91
The prion protein-like gene Doppel is aberrantly expressed in astrocytic tumors 90
Molecular and cellular insights into the aberrant expression of the prion protein-like gene doppel in astrocytic tumors 90
Influence of fibronectine on the fibrillogenesis of type I and type III collagen 88
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 87
Pyruvate kinase deficiency: Biochemical characterization of two mutations causing inability of the enzyme to properly bind substrates 84
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 83
An essential lysine in the substrate-binding of ornithine carbamoyl transferase 82
Two forms of pyruvate kinase in Escherichia coli. A comparison of chemical and molecular properties 82
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 82
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 82
A simple procedure for the purification of neutral salt soluble type I collagene from skin. 82
Helicobacter pylori: from gene to Diagnostic Tool 81
Affinity labelling of the catalytic and allosteric ATP binding sites on pyruvate kinase type I from Escherichia coli. 80
Biochemical signatures of doppel (Dpl) protein in human glioblastoma to support prediction in tumor malignancy 79
Helicobacter pylori L-asparaginase: from Gene to Diagnostic Tool 79
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 79
Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 79
SELECTION OF MICROFUNGI WITH HIGH LIPOLYTIC ACTIVITYAND THEIR LIPASE CHARACTERIZATION 78
Biochemistry of Lipolytic Enzymes Secreted by Penicillium solitum and Cladosporium cladosporioides 78
Expanding Targets for a Metabolic Therapy of Cancer: L- Asparaginase 77
AMP- and fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. 76
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. Natures of bonds involved in the allosteric mecchanism. 76
Molecular cloning and characterisation of Helicobacter pylori L-asparaginase 76
Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene. 76
Purification and molecular properties of the AMP-activated pyruvate kinase from Escherichia coli. 74
A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency. 74
A comparative study on liver ornithine carbamoyl transferase from a marine mammal Stenella and a elasmobranch Sphyrna zygaena. 73
Reactivity of the fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli with pyridoxal 5’-phosphate 73
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 73
Erythrocyte Adenylate Kinase Deficiency: First In-Depth Biochemical Characterization of the Y164C Mutant Enzyme Causing Hemolytic Anemia 72
Molecular Insights on Pathogenic Effects of MutationsCausing Phosphoglycerate Kinase Deficiency 71
Inosine monophosphate dehydrogenase activity after mycophenolate mofetil in renal transplant patients receiving different immunosupressive combined therapy and stable after at least three months' administration. 71
Premio Ricercatissimi 2008 70
Pyrimidine 5' Nucleotidase Deficiency: Clinical and Molecular Characterization of Two New Italian Patients 70
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 70
Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells 69
Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5-Nucleotidase Causing Hereditary Hemolytic Anemia. 69
The allosteric regulation of pyruvate kinase. 69
EXPRESSION AND CHARACTERIZATION OF THE BOVINE PRION DOPPEL 68
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 68
Molecular basis of pyrimidine 5'-nucleotidase deficiency caused by 3 newly identified missense mutations (c.187T>C, c.469G>C and c.740T>C) and a tabulation of known mutations 68
Bacterial pyruvate kinases have a shorter N-terminal domain 68
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 67
Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase. 66
Molecular and functional characterization of a lethal variant of pyruvate kinase deficiency 65
The allosteric regulation of pyruvate kinase 64
Functional and structural characterization of ovine ornithine transcarbamoylase 64
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization. 64
L-ASPARAGINASE FROM HELICOBACTER PYLORI 63
PYRUVATE KINASE DEFICIENCY: MOLECULAR AND FUNCTIONAL CHARACTERISATION OF A LETHAL VARIANT 63
Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia 62
Pyrimidine 5'-nucleotidase activities detected in real samples by means of micellar electrokinetic chromatography. 60
Hereditary pyrimidine 5'-nucleotidase deficiency: from genetics to clinical manifestations. 60
Two new mutations of the P5'N-1 gene found in Italian patients with hereditary hemolytic anemia: the molecular basis of the red cell enzyme disorder. 60
Hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency: a biochemical, genetic and clinical overview 60
Red cell pyruvate kinase deficiency: molecular and clinical aspects 60
Red cell pyruvate kinase deficiency: 17 new mutations of the PK-LR gene 60
Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency 60
Molecular Basis of Hemolytic Anemia: First Biochemical Characterization of Wild-Type and N190S Mutant Human Erythrocyte Pyrimidine 5'-Nucleotidase. 59
Investigating the Molecular Bases of the Phosphoglycerate Kinase Deficiency: Characterization ofG158V, R206P, V266M and D285V Pathological Variants. 58
Pyruvate kinase deficiency : The genotype-phenotype association 57
Protein Stability, Folding and Misfolding in Human PGK1 Deficiency 55
Functional Analysis of Two Mutants of Pyrimidine 5’ Nucleotidase Causing Nonspherocytic Hemolytic Anemia 55
Functional analysis of pyrimidine 5'-nucleotidase mutants causing nonspherocytic hemolytic anemia 53
PHOSPHOGLYCERATE KINASE DEFICIENCY: FUNCTIONAL PROPERTIES OF THE L89P, K191DEL, C316R AND A354P PATHOLOGICAL VARIANTS 52
Monitoring Inosine monophosphate dehydrogenase (IMPDH) in kidney transplant recipients 49
Molecular Cloning and Characterisation of Helicobacter Pylori L-Asparaginase: A Cytotoxic Factor with Potential Biomedical Applications 48
Helicobacter pylori L-asparaginase: A promising chemotherapeutic agent 47
Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase 43
Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy 39
The interplay between protein stability and folding co-operativity in loss-of-function genetic disease: The case of human PGK1 deficiency. 35
Protein stability, folding and misfolding in human PGK1 deficiency 18
Totale 6.146
Categoria #
all - tutte 24.853
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.853


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20206 0 0 0 0 0 0 0 0 0 0 0 6
2020/2021605 78 46 25 63 4 79 8 87 19 91 86 19
2021/2022450 6 7 9 6 26 17 15 32 32 20 51 229
2022/20231.411 124 122 9 128 157 155 1 64 594 8 32 17
2023/2024516 121 70 6 43 50 141 7 32 0 12 20 14
2024/20251.198 28 97 45 44 32 52 41 73 322 23 179 262
Totale 6.146