VALENTINI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 2.278
EU - Europa 1.716
AS - Asia 1.159
AF - Africa 6
SA - Sud America 6
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.168
Nazione #
US - Stati Uniti d'America 2.263
CN - Cina 1.039
IE - Irlanda 519
UA - Ucraina 328
FI - Finlandia 261
DE - Germania 178
SE - Svezia 135
IT - Italia 109
SG - Singapore 92
GB - Regno Unito 84
FR - Francia 44
BE - Belgio 30
CA - Canada 14
NL - Olanda 9
IN - India 7
IR - Iran 6
JP - Giappone 6
CZ - Repubblica Ceca 4
MU - Mauritius 4
AR - Argentina 3
RU - Federazione Russa 3
AT - Austria 2
CL - Cile 2
EG - Egitto 2
GR - Grecia 2
HK - Hong Kong 2
MD - Moldavia 2
PK - Pakistan 2
RO - Romania 2
AU - Australia 1
BR - Brasile 1
CH - Svizzera 1
ES - Italia 1
EU - Europa 1
IQ - Iraq 1
JO - Giordania 1
LV - Lettonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
VN - Vietnam 1
Totale 5.168
Città #
Dublin 519
Chandler 505
Jacksonville 372
Nanjing 270
Ann Arbor 152
Boardman 146
Beijing 145
Nanchang 130
Ashburn 128
Wilmington 104
Helsinki 97
Lawrence 85
Medford 85
Princeton 85
Shenyang 74
Hebei 70
Changsha 68
New York 67
Jiaxing 61
Singapore 61
Hangzhou 59
Tianjin 58
Shanghai 45
Woodbridge 39
Milan 38
Brussels 30
Verona 25
Munich 17
Norwalk 15
Dearborn 14
Falls Church 14
Pavia 12
Auburn Hills 11
Los Angeles 10
Des Moines 9
Fairfield 9
Tappahannock 9
Toronto 9
Jinan 8
Piscataway 8
Seattle 8
Kunming 7
Taizhou 7
Chicago 6
Ningbo 6
Kiel 5
London 5
Tokyo 5
Brno 4
Sacramento 4
San Genesio ed Uniti 4
Zhengzhou 4
Andover 3
Birmingham 3
Fuzhou 3
Groningen 3
Zanjan 3
Buenos Aires 2
Castenaso 2
Changchun 2
Chisinau 2
Costa Mesa 2
Haikou 2
Houston 2
Islamabad 2
Leawood 2
Monmouth Junction 2
Paderno Dugnano 2
Vienna 2
Amman 1
Andrushivka 1
Athens 1
Auckland 1
Baghdad 1
Bengaluru 1
Bratislava 1
Cambridge 1
Charlottetown 1
Chorley 1
Dallas 1
Delhi 1
Faenza 1
Falkenstein 1
Focsani 1
Fontana 1
Frankfurt am Main 1
Guangzhou 1
Hefei 1
Ho Chi Minh City 1
Hyderabad 1
Madrid 1
Melbourne 1
Mumbai 1
Muskego 1
Natchez 1
New Westminster 1
Newark 1
Newbury Park 1
Nürnberg 1
Orange 1
Totale 3.798
Nome #
The prion-like doppel protein is soluble in astrocytic tumor 93
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 88
Divergent biding sites in pyruvate kinase I and II from Escherichia coli. 87
Expanding targets for a metabolic therapy of cancer: L-asparaginase 87
Primary structure of three peptides at the catalytic and allosteric sites of the fructose 1,6-bisphosphate-activated pyruvate kinase from Escherichia coli 84
Letter to the editor regarding Shibayama et al.: Biochemical and pathophysiological characterization of Helicobacter pylori asparaginase. 83
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli: ligands promoted conformational changes 83
Generation of Mutants of Helicobacter pylori L-Asparaginase 82
The prion protein-like gene Doppel is aberrantly expressed in astrocytic tumors 81
Molecular and cellular insights into the aberrant expression of the prion protein-like gene doppel in astrocytic tumors 81
Phosphoglycerate Kinase Deficiency: Characterization of the Wild-Type Enzyme and Three Pathological Variants Generated from C.140T>a, C.491A>T and C.959G>a Mutations 80
Influence of fibronectine on the fibrillogenesis of type I and type III collagen 80
Aberrant Doppel Protein Expression in Human Astrocytic Tumors 78
Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells 76
Two forms of pyruvate kinase in Escherichia coli. A comparison of chemical and molecular properties 75
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 74
Pyruvate kinase deficiency: Biochemical characterization of two mutations causing inability of the enzyme to properly bind substrates 72
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 72
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants 72
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 71
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 70
Ectopic expression of the prion-like protein doppel in human astrocytoma cells 70
Helicobacter pylori: from gene to Diagnostic Tool 69
Purification and molecular properties of the AMP-activated pyruvate kinase from Escherichia coli. 67
Affinity labelling of the catalytic and allosteric ATP binding sites on pyruvate kinase type I from Escherichia coli. 67
Biochemical signatures of doppel (Dpl) protein in human glioblastoma to support prediction in tumor malignancy 67
Erythrocyte Adenylate Kinase Deficiency: First In-Depth Biochemical Characterization of the Y164C Mutant Enzyme Causing Hemolytic Anemia 67
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 67
A simple procedure for the purification of neutral salt soluble type I collagene from skin. 67
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. Natures of bonds involved in the allosteric mecchanism. 66
Molecular cloning and characterisation of Helicobacter pylori L-asparaginase 66
Helicobacter pylori L-asparaginase: from Gene to Diagnostic Tool 66
Biochemistry of Lipolytic Enzymes Secreted by Penicillium solitum and Cladosporium cladosporioides 65
An essential lysine in the substrate-binding of ornithine carbamoyl transferase 64
A comparative study on liver ornithine carbamoyl transferase from a marine mammal Stenella and a elasmobranch Sphyrna zygaena. 64
SELECTION OF MICROFUNGI WITH HIGH LIPOLYTIC ACTIVITYAND THEIR LIPASE CHARACTERIZATION 64
AMP- and fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. 63
Inosine monophosphate dehydrogenase activity after mycophenolate mofetil in renal transplant patients receiving different immunosupressive combined therapy and stable after at least three months' administration. 63
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 63
Reactivity of the fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli with pyridoxal 5’-phosphate 62
Premio Ricercatissimi 2008 62
Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 62
Pyrimidine 5' Nucleotidase Deficiency: Clinical and Molecular Characterization of Two New Italian Patients 62
Expanding Targets for a Metabolic Therapy of Cancer: L- Asparaginase 61
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 60
Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5-Nucleotidase Causing Hereditary Hemolytic Anemia. 59
A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency. 59
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 59
EXPRESSION AND CHARACTERIZATION OF THE BOVINE PRION DOPPEL 58
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 58
Bacterial pyruvate kinases have a shorter N-terminal domain 58
Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene. 58
Molecular and functional characterization of a lethal variant of pyruvate kinase deficiency 57
The allosteric regulation of pyruvate kinase 57
PYRUVATE KINASE DEFICIENCY: MOLECULAR AND FUNCTIONAL CHARACTERISATION OF A LETHAL VARIANT 57
Molecular basis of pyrimidine 5'-nucleotidase deficiency caused by 3 newly identified missense mutations (c.187T>C, c.469G>C and c.740T>C) and a tabulation of known mutations 57
The allosteric regulation of pyruvate kinase. 57
Functional and structural characterization of ovine ornithine transcarbamoylase 56
Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells 56
L-ASPARAGINASE FROM HELICOBACTER PYLORI 55
Molecular Insights on Pathogenic Effects of MutationsCausing Phosphoglycerate Kinase Deficiency 55
Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency 55
Hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency: a biochemical, genetic and clinical overview 54
Red cell pyruvate kinase deficiency: molecular and clinical aspects 54
Red cell pyruvate kinase deficiency: 17 new mutations of the PK-LR gene 53
Pyrimidine 5'-nucleotidase activities detected in real samples by means of micellar electrokinetic chromatography. 52
Pyruvate kinase deficiency : The genotype-phenotype association 52
Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase. 52
Hereditary pyrimidine 5'-nucleotidase deficiency: from genetics to clinical manifestations. 51
Two new mutations of the P5'N-1 gene found in Italian patients with hereditary hemolytic anemia: the molecular basis of the red cell enzyme disorder. 51
Investigating the Molecular Bases of the Phosphoglycerate Kinase Deficiency: Characterization ofG158V, R206P, V266M and D285V Pathological Variants. 51
Molecular Basis of Hemolytic Anemia: First Biochemical Characterization of Wild-Type and N190S Mutant Human Erythrocyte Pyrimidine 5'-Nucleotidase. 51
Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia 50
Functional Analysis of Two Mutants of Pyrimidine 5’ Nucleotidase Causing Nonspherocytic Hemolytic Anemia 49
Protein Stability, Folding and Misfolding in Human PGK1 Deficiency 48
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization. 45
Functional analysis of pyrimidine 5'-nucleotidase mutants causing nonspherocytic hemolytic anemia 44
Monitoring Inosine monophosphate dehydrogenase (IMPDH) in kidney transplant recipients 44
Molecular Cloning and Characterisation of Helicobacter Pylori L-Asparaginase: A Cytotoxic Factor with Potential Biomedical Applications 40
Helicobacter pylori L-asparaginase: A promising chemotherapeutic agent 39
PHOSPHOGLYCERATE KINASE DEFICIENCY: FUNCTIONAL PROPERTIES OF THE L89P, K191DEL, C316R AND A354P PATHOLOGICAL VARIANTS 35
Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase 34
The interplay between protein stability and folding co-operativity in loss-of-function genetic disease: The case of human PGK1 deficiency. 30
Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy 29
Protein stability, folding and misfolding in human PGK1 deficiency 12
Totale 5.214
Categoria #
all - tutte 20.191
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.191


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020374 0 0 0 0 0 65 18 79 16 109 81 6
2020/2021605 78 46 25 63 4 79 8 87 19 91 86 19
2021/2022450 6 7 9 6 26 17 15 32 32 20 51 229
2022/20231.411 124 122 9 128 157 155 1 64 594 8 32 17
2023/2024516 121 70 6 43 50 141 7 32 0 12 20 14
2024/2025266 28 97 45 44 32 20 0 0 0 0 0 0
Totale 5.214