VALENTINI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 3.623
AS - Asia 2.698
EU - Europa 2.298
SA - Sud America 289
AF - Africa 87
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 9.002
Nazione #
US - Stati Uniti d'America 3.538
CN - Cina 1.427
SG - Singapore 524
IE - Irlanda 521
UA - Ucraina 336
FI - Finlandia 293
HK - Hong Kong 265
DE - Germania 262
RU - Federazione Russa 225
BR - Brasile 208
VN - Vietnam 198
FR - Francia 144
SE - Svezia 144
IT - Italia 128
GB - Regno Unito 121
IN - India 76
ZA - Sudafrica 49
CA - Canada 47
AR - Argentina 32
BE - Belgio 30
ID - Indonesia 29
JP - Giappone 24
MX - Messico 24
NL - Olanda 24
BD - Bangladesh 22
TR - Turchia 22
IQ - Iraq 21
PK - Pakistan 14
ES - Italia 13
PL - Polonia 13
SA - Arabia Saudita 12
CO - Colombia 10
MA - Marocco 10
EC - Ecuador 8
IR - Iran 8
UZ - Uzbekistan 8
CZ - Repubblica Ceca 7
VE - Venezuela 7
AE - Emirati Arabi Uniti 6
CL - Cile 6
LT - Lituania 6
MY - Malesia 6
PE - Perù 6
AT - Austria 5
AU - Australia 5
JO - Giordania 5
LV - Lettonia 5
BO - Bolivia 4
DZ - Algeria 4
MU - Mauritius 4
PA - Panama 4
PH - Filippine 4
PY - Paraguay 4
RO - Romania 4
TN - Tunisia 4
AL - Albania 3
EG - Egitto 3
ET - Etiopia 3
IL - Israele 3
KG - Kirghizistan 3
KZ - Kazakistan 3
SN - Senegal 3
UY - Uruguay 3
AZ - Azerbaigian 2
BB - Barbados 2
CH - Svizzera 2
CR - Costa Rica 2
CY - Cipro 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GR - Grecia 2
JM - Giamaica 2
KE - Kenya 2
LB - Libano 2
MD - Moldavia 2
NP - Nepal 2
TH - Thailandia 2
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
BS - Bahamas 1
BY - Bielorussia 1
CG - Congo 1
CV - Capo Verde 1
EU - Europa 1
GM - Gambi 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
KR - Corea 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
ML - Mali 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PT - Portogallo 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 9.002
Città #
Dublin 520
Chandler 505
Jacksonville 372
San Jose 343
Beijing 292
Ashburn 270
Nanjing 270
Hong Kong 259
Singapore 250
Dallas 167
Ann Arbor 152
Boardman 147
Nanchang 131
Los Angeles 109
Helsinki 108
Wilmington 104
New York 87
Lawrence 85
Medford 85
Princeton 85
Shenyang 76
Lauterbourg 72
Changsha 70
Hebei 70
Munich 68
Ho Chi Minh City 62
Jiaxing 62
Tianjin 62
Hangzhou 61
Hanoi 51
Shanghai 50
Johannesburg 43
Buffalo 40
Milan 39
Woodbridge 39
Moscow 36
Brussels 30
Orem 25
São Paulo 25
Verona 25
Council Bluffs 23
Tokyo 21
Turku 21
Chennai 17
Denver 17
Redondo Beach 17
Frankfurt am Main 15
Norwalk 15
Atlanta 14
Chicago 14
Dearborn 14
Falls Church 14
Montreal 14
Pavia 14
Boston 13
Santa Clara 13
Toronto 13
London 12
Auburn Hills 11
Brooklyn 11
Da Nang 11
Jinan 11
Phoenix 11
The Dalles 11
Warsaw 11
Haiphong 10
Mexico City 10
Mumbai 10
Piscataway 10
Des Moines 9
Fairfield 9
Seattle 9
Stockholm 9
Tappahannock 9
Amsterdam 8
Buenos Aires 8
Houston 8
Tashkent 8
Ankara 7
Curitiba 7
Kunming 7
Lahore 7
Rio de Janeiro 7
Taizhou 7
Baghdad 6
Columbus 6
Jakarta 6
Manchester 6
Ningbo 6
Nuremberg 6
San Francisco 6
Falkenstein 5
Fuzhou 5
Hải Dương 5
Istanbul 5
Jeddah 5
Kiel 5
Lima 5
Poplar 5
Roubaix 5
Totale 5.951
Nome #
Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells 165
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 159
Aberrant Doppel Protein Expression in Human Astrocytic Tumors 150
Divergent biding sites in pyruvate kinase I and II from Escherichia coli. 147
Letter to the editor regarding Shibayama et al.: Biochemical and pathophysiological characterization of Helicobacter pylori asparaginase. 145
The prion-like doppel protein is soluble in astrocytic tumor 135
Generation of Mutants of Helicobacter pylori L-Asparaginase 134
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants 134
Primary structure of three peptides at the catalytic and allosteric sites of the fructose 1,6-bisphosphate-activated pyruvate kinase from Escherichia coli 133
An essential lysine in the substrate-binding of ornithine carbamoyl transferase 132
Phosphoglycerate Kinase Deficiency: Characterization of the Wild-Type Enzyme and Three Pathological Variants Generated from C.140T>a, C.491A>T and C.959G>a Mutations 132
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli: ligands promoted conformational changes 129
Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 129
Molecular and cellular insights into the aberrant expression of the prion protein-like gene doppel in astrocytic tumors 128
Expanding targets for a metabolic therapy of cancer: L-asparaginase 128
Biochemistry of Lipolytic Enzymes Secreted by Penicillium solitum and Cladosporium cladosporioides 128
A simple procedure for the purification of neutral salt soluble type I collagene from skin. 127
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 126
Crystallization and preliminary X-ray analysis of pyruvate kinase type I from Escherichia coli. 126
Expanding Targets for a Metabolic Therapy of Cancer: L- Asparaginase 125
The prion protein-like gene Doppel is aberrantly expressed in astrocytic tumors 122
Affinity labelling of the catalytic and allosteric ATP binding sites on pyruvate kinase type I from Escherichia coli. 121
Ectopic expression of the prion-like protein doppel in human astrocytoma cells 121
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition 121
Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene. 121
Bacterial pyruvate kinases have a shorter N-terminal domain 120
Recombinant pyruvate kinase type I from Escherichia coli:overproduction and revised C-terminus of the polypeptide 119
AMP- and fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. 118
Biochemical signatures of doppel (Dpl) protein in human glioblastoma to support prediction in tumor malignancy 118
Influence of fibronectine on the fibrillogenesis of type I and type III collagen 118
A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency. 118
Pyruvate kinase deficiency: Biochemical characterization of two mutations causing inability of the enzyme to properly bind substrates 117
A comparative study on liver ornithine carbamoyl transferase from a marine mammal Stenella and a elasmobranch Sphyrna zygaena. 116
Helicobacter pylori L-asparaginase: from Gene to Diagnostic Tool 116
Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells 116
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 115
The allosteric regulation of pyruvate kinase. 115
Helicobacter pylori: from gene to Diagnostic Tool 113
Molecular Insights on Pathogenic Effects of MutationsCausing Phosphoglycerate Kinase Deficiency 112
Two forms of pyruvate kinase in Escherichia coli. A comparison of chemical and molecular properties 111
Fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli. Natures of bonds involved in the allosteric mecchanism. 111
Molecular cloning and characterisation of Helicobacter pylori L-asparaginase 111
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization. 110
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 109
Characterization of a pyrimidine 5'-nucleotidase mutant form (G214R) causing hereditary hemolytic anemia. 109
SELECTION OF MICROFUNGI WITH HIGH LIPOLYTIC ACTIVITYAND THEIR LIPASE CHARACTERIZATION 107
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia 107
Reactivity of the fructose 1,6-biphosphate-activated pyruvate kinase from Escherichia coli with pyridoxal 5’-phosphate 106
Premio Ricercatissimi 2008 104
Investigating the Molecular Bases of the Phosphoglycerate Kinase Deficiency: Characterization ofG158V, R206P, V266M and D285V Pathological Variants. 101
Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia 100
Molecular Characterization of Three New Mutant Enzymes of Pyrimidine 5-Nucleotidase Causing Hereditary Hemolytic Anemia. 97
Erythrocyte Adenylate Kinase Deficiency: First In-Depth Biochemical Characterization of the Y164C Mutant Enzyme Causing Hemolytic Anemia 96
EXPRESSION AND CHARACTERIZATION OF THE BOVINE PRION DOPPEL 95
Pyrimidine 5' Nucleotidase Deficiency: Clinical and Molecular Characterization of Two New Italian Patients 95
Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase. 94
Molecular basis of pyrimidine 5'-nucleotidase deficiency caused by 3 newly identified missense mutations (c.187T>C, c.469G>C and c.740T>C) and a tabulation of known mutations 93
Purification and molecular properties of the AMP-activated pyruvate kinase from Escherichia coli. 92
Human erythrocyte pyruvate kinase:characterization of the recombinant enzyme and a mutant form(R510Q))causing nonspherocytic hemolytic anemia. 90
Pyrimidine 5'-nucleotidase activities detected in real samples by means of micellar electrokinetic chromatography. 89
Molecular Basis of Hemolytic Anemia: First Biochemical Characterization of Wild-Type and N190S Mutant Human Erythrocyte Pyrimidine 5'-Nucleotidase. 89
Molecular and functional characterization of a lethal variant of pyruvate kinase deficiency 88
Inosine monophosphate dehydrogenase activity after mycophenolate mofetil in renal transplant patients receiving different immunosupressive combined therapy and stable after at least three months' administration. 88
Functional and structural characterization of ovine ornithine transcarbamoylase 87
Red cell pyruvate kinase deficiency: molecular and clinical aspects 87
PYRUVATE KINASE DEFICIENCY: MOLECULAR AND FUNCTIONAL CHARACTERISATION OF A LETHAL VARIANT 87
Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency 87
The allosteric regulation of pyruvate kinase 86
Hereditary pyrimidine 5'-nucleotidase deficiency: from genetics to clinical manifestations. 85
PHOSPHOGLYCERATE KINASE DEFICIENCY: FUNCTIONAL PROPERTIES OF THE L89P, K191DEL, C316R AND A354P PATHOLOGICAL VARIANTS 84
Pyruvate kinase deficiency : The genotype-phenotype association 83
Red cell pyruvate kinase deficiency: 17 new mutations of the PK-LR gene 83
Two new mutations of the P5'N-1 gene found in Italian patients with hereditary hemolytic anemia: the molecular basis of the red cell enzyme disorder. 82
Hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency: a biochemical, genetic and clinical overview 81
Functional analysis of pyrimidine 5'-nucleotidase mutants causing nonspherocytic hemolytic anemia 79
L-ASPARAGINASE FROM HELICOBACTER PYLORI 79
The interplay between protein stability and folding co-operativity in loss-of-function genetic disease: The case of human PGK1 deficiency. 79
Molecular Cloning and Characterisation of Helicobacter Pylori L-Asparaginase: A Cytotoxic Factor with Potential Biomedical Applications 78
Functional Analysis of Two Mutants of Pyrimidine 5’ Nucleotidase Causing Nonspherocytic Hemolytic Anemia 78
Protein Stability, Folding and Misfolding in Human PGK1 Deficiency 77
Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase 77
Monitoring Inosine monophosphate dehydrogenase (IMPDH) in kidney transplant recipients 69
Helicobacter pylori L-asparaginase: A promising chemotherapeutic agent 68
Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy 58
Protein stability, folding and misfolding in human PGK1 deficiency 33
Totale 9.048
Categoria #
all - tutte 34.960
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.960


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202119 0 0 0 0 0 0 0 0 0 0 0 19
2021/2022450 6 7 9 6 26 17 15 32 32 20 51 229
2022/20231.411 124 122 9 128 157 155 1 64 594 8 32 17
2023/2024516 121 70 6 43 50 141 7 32 0 12 20 14
2024/20251.228 28 97 45 44 32 52 41 73 322 23 179 292
2025/20262.872 234 197 300 370 357 162 502 111 304 210 86 39
Totale 9.048