CHIARELLI, LAURENT ROBERT
CHIARELLI, LAURENT ROBERT
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1.
2015-01-01 Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T.
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity.
2014-01-01 Naik, M; Humnabadkar, V; Tantry, Sj; Panda, M; Narayan, A; Guptha, S; Panduga, V; Manjrekar, P; Jena, Lk; Koushik, K; Shanbhag, G; Jatheendranath, S; M. R., M.; Gorai, G; Bathula, C; Rudrapatna, S; Achar, V; Sharma, S; Ambady, A; Hegde, N; Mahadevaswamy, J; Kaur, P; Sambandamurthy, Vk; Awasthy, D; Narayanan, C; Ravishankar, S; Madhavapeddi, P; Reddy, J; Kr, P; Saralaya, R; Chatterji, M; Whiteaker, J; Mclaughlin, R; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA; Binda, Claudia; Neres, Jp; Dhar, N; Signorino Gelo, F; Mckinney, J; Ramachandran, V; Shandil, R; Tommasi, R; Iyer, Ps; Narayanan, S; Hosagrahara, V; Kavanagh, S; Dinesh, N; Ghorpade, S. R.
6-Hydroxy-2-methylbenzofuran-4-carboxylic Acid
2020-01-01 Mori, M; Meneghetti, F; Chiarelli, LAURENT ROBERT; Diego, A; Nava, D; Gelain, A; Cazzaniga, G; Villa, S; Pini, E
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis
2021-01-01 Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan
A dual-target approach in anti-tuberculosis therapy: new MptpB/MbtI.
2020-01-01 Cazzaniga, G; Mori, M; Gelain, A; Pini, E; Stelitano, G; Chiarelli, Lr; Meneghetti, F; Villa, S.
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis MbtI and MPtpB
2021-01-01 Stelitano, G; Cazzaniga, G; Mori, M; Villa, S; Meneghetti, F; Chiarelli, Lr.
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
2018-01-01 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis
2022-01-01 Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia
A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency.
2012-01-01 Bianchi, P.; Fermo, E.; Chiarelli, Laurent; Maggi, Maristella; Mandarà, G. M. L.; Vercellati, C.; Marcello, A. P.; Barcellini, W.; Cortelezzi, A.; Valentini, Giovanna; Zanella, A.
A new promising bactericidal compound against Burkholderia cenocepacia.
2016-01-01 Buroni, S; Gislason, As; Scoffone, Vc; Stietz, Ms; Chiarelli, Laurent; Azzalin, A; Makarov, V; Cardona, St; Riccardi, G.
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization.
2012-01-01 Fermo, E.; Bianchi, P.; Chiarelli, Laurent; Maggi, M.; Mandarà, G. M. L.; Vercellati, C.; Marcello, A. P.; Barcellini, W.; Cortelezzi, A.; Valentini, Giovanna; Zanella, A.
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors
2017-01-01 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
Aberrant Doppel Protein Expression in Human Astrocytic Tumors
2006-01-01 Rognoni, Paola; Chiarelli, Laurent; Azzalin, Alberto; Chen, Y; Comincini, Sergio; Valentini, Giovanna
Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells
2005-01-01 Azzalin, Alberto; DEL VECCHIO, Igor; Chiarelli, Laurent; Valentini, Giovanna; Comincini, Sergio; Ferretti, Luca
Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase.
2011-01-01 Chiarelli, Laurent; Pasquetto, MARIA VALENTINA; Valentini, Giovanna; Scotti, Claudia
An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis
2019-01-01 Mori, Matteo; Sammartino, José Camilla; Costantino, Luca; Gelain, Arianna; Meneghetti, Fiorella; Villa, Stefania; Chiarelli, Laurent Roberto
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis
2011-01-01 De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA
Antibiotics sustainability: another issue in the fight against antimicrobial resistance.
2022-01-01 Buroni, Silvia; Chiarelli, Laurent
Antivirulence compounds: a future direction to overcome antibiotic resistance?
2020-01-01 Buroni, Silvia; Chiarelli, Laurent R
BEL β-trefoil: a novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms.
2013-01-01 Bovi, M; Cenci, L; Perduca, M; Capaldi, S; Carrizo, Me; Civiero, L; Chiarelli, Laurent; Galliano, Monica; Monaco, H. L.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. | 1-gen-2015 | Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T. | |
| 4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. | 1-gen-2014 | Naik, M; Humnabadkar, V; Tantry, Sj; Panda, M; Narayan, A; Guptha, S; Panduga, V; Manjrekar, P; Jena, Lk; Koushik, K; Shanbhag, G; Jatheendranath, S; M. R., M.; Gorai, G; Bathula, C; Rudrapatna, S; Achar, V; Sharma, S; Ambady, A; Hegde, N; Mahadevaswamy, J; Kaur, P; Sambandamurthy, Vk; Awasthy, D; Narayanan, C; Ravishankar, S; Madhavapeddi, P; Reddy, J; Kr, P; Saralaya, R; Chatterji, M; Whiteaker, J; Mclaughlin, R; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA; Binda, Claudia; Neres, Jp; Dhar, N; Signorino Gelo, F; Mckinney, J; Ramachandran, V; Shandil, R; Tommasi, R; Iyer, Ps; Narayanan, S; Hosagrahara, V; Kavanagh, S; Dinesh, N; Ghorpade, S. R. | |
| 6-Hydroxy-2-methylbenzofuran-4-carboxylic Acid | 1-gen-2020 | Mori, M; Meneghetti, F; Chiarelli, LAURENT ROBERT; Diego, A; Nava, D; Gelain, A; Cazzaniga, G; Villa, S; Pini, E | |
| A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis | 1-gen-2021 | Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan | |
| A dual-target approach in anti-tuberculosis therapy: new MptpB/MbtI. | 1-gen-2020 | Cazzaniga, G; Mori, M; Gelain, A; Pini, E; Stelitano, G; Chiarelli, Lr; Meneghetti, F; Villa, S. | |
| A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis MbtI and MPtpB | 1-gen-2021 | Stelitano, G; Cazzaniga, G; Mori, M; Villa, S; Meneghetti, F; Chiarelli, Lr. | |
| A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK | 1-gen-2018 | Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr | |
| A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis | 1-gen-2022 | Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia | |
| A new mutation of the pgk1 gene detected in an italian patient affected by phosphoglycerate kinase deficiency. | 1-gen-2012 | Bianchi, P.; Fermo, E.; Chiarelli, Laurent; Maggi, Maristella; Mandarà, G. M. L.; Vercellati, C.; Marcello, A. P.; Barcellini, W.; Cortelezzi, A.; Valentini, Giovanna; Zanella, A. | |
| A new promising bactericidal compound against Burkholderia cenocepacia. | 1-gen-2016 | Buroni, S; Gislason, As; Scoffone, Vc; Stietz, Ms; Chiarelli, Laurent; Azzalin, A; Makarov, V; Cardona, St; Riccardi, G. | |
| A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: molecular and functional characterization. | 1-gen-2012 | Fermo, E.; Bianchi, P.; Chiarelli, Laurent; Maggi, M.; Mandarà, G. M. L.; Vercellati, C.; Marcello, A. P.; Barcellini, W.; Cortelezzi, A.; Valentini, Giovanna; Zanella, A. | |
| A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors | 1-gen-2017 | Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent | |
| Aberrant Doppel Protein Expression in Human Astrocytic Tumors | 1-gen-2006 | Rognoni, Paola; Chiarelli, Laurent; Azzalin, Alberto; Chen, Y; Comincini, Sergio; Valentini, Giovanna | |
| Absence of interaction between doppel and GFAP, Grb2, PrPC proteins in human tumor astrocytic cells | 1-gen-2005 | Azzalin, Alberto; DEL VECCHIO, Igor; Chiarelli, Laurent; Valentini, Giovanna; Comincini, Sergio; Ferretti, Luca | |
| Aeroplane shaped crystal of a mutant ofHelicobacter pylori L-asparaginase. | 1-gen-2011 | Chiarelli, Laurent; Pasquetto, MARIA VALENTINA; Valentini, Giovanna; Scotti, Claudia | |
| An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis | 1-gen-2019 | Mori, Matteo; Sammartino, José Camilla; Costantino, Luca; Gelain, Arianna; Meneghetti, Fiorella; Villa, Stefania; Chiarelli, Laurent Roberto | |
| Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis | 1-gen-2011 | De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA | |
| Antibiotics sustainability: another issue in the fight against antimicrobial resistance. | 1-gen-2022 | Buroni, Silvia; Chiarelli, Laurent | |
| Antivirulence compounds: a future direction to overcome antibiotic resistance? | 1-gen-2020 | Buroni, Silvia; Chiarelli, Laurent R | |
| BEL β-trefoil: a novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms. | 1-gen-2013 | Bovi, M; Cenci, L; Perduca, M; Capaldi, S; Carrizo, Me; Civiero, L; Chiarelli, Laurent; Galliano, Monica; Monaco, H. L. |