IRIS
GHERARDI, ERMANNO
 Distribuzione geografica
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Continente #
NA - Nord America 1.953
EU - Europa 1.327
AS - Asia 972
SA - Sud America 6
OC - Oceania 4
AF - Africa 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 4.267
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Nazione #
US - Stati Uniti d'America 1.945
CN - Cina 885
IE - Irlanda 370
UA - Ucraina 274
FI - Finlandia 162
DE - Germania 135
SE - Svezia 129
IT - Italia 103
GB - Regno Unito 90
SG - Singapore 72
FR - Francia 38
BE - Belgio 16
CA - Canada 6
JP - Giappone 6
IN - India 5
BO - Bolivia 3
AU - Australia 2
BR - Brasile 2
CH - Svizzera 2
CZ - Repubblica Ceca 2
EU - Europa 2
NL - Olanda 2
NZ - Nuova Zelanda 2
RU - Federazione Russa 2
VN - Vietnam 2
AE - Emirati Arabi Uniti 1
AT - Austria 1
CL - Cile 1
IR - Iran 1
KE - Kenya 1
LU - Lussemburgo 1
MU - Mauritius 1
MX - Messico 1
PA - Panama 1
ZA - Sudafrica 1
Totale 4.267
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Città #
Chandler 512
Dublin 368
Jacksonville 306
Nanjing 289
Boardman 126
Ashburn 112
Nanchang 109
Princeton 79
Lawrence 78
Wilmington 77
Beijing 75
Hebei 75
Ann Arbor 74
Shenyang 71
Changsha 65
Medford 52
Jiaxing 45
Singapore 41
Tianjin 39
Milan 35
Hangzhou 27
Helsinki 24
Shanghai 24
Woodbridge 22
Norwalk 21
Verona 20
Pavia 18
Brussels 16
Seattle 12
Kunming 11
New York 8
Falls Church 7
Munich 7
Zhengzhou 7
Los Angeles 6
Fairfield 5
Jinan 5
Washington 5
Auburn Hills 4
Dallas 4
Pune 4
Shenzhen 4
Taizhou 4
Toronto 4
Cosenza 3
Guangzhou 3
Nürnberg 3
Prineville 3
San Francisco 3
Toyonaka 3
Arlesheim 2
Brno 2
Cochabamba 2
Des Moines 2
Dong Ket 2
Katsushika 2
Lanzhou 2
Leawood 2
Ningbo 2
Padova 2
Peruibe 2
Ardabil 1
Auckland 1
Bedford 1
Borås 1
Boston 1
Buccinasco 1
Büdelsdorf 1
Centurion 1
Changchun 1
Chicago 1
Chongqing 1
Cowansville 1
Dubai 1
Gavirate 1
Geislingen an der Steige 1
Inglewood 1
Kolkata 1
La Paz 1
Luxembourg 1
Manduria 1
Melbourne 1
Menlo Park 1
Nairobi 1
Orange 1
Qingdao 1
Redwood City 1
San Martino Valle Caudina 1
Sandston 1
Santa Clara 1
Shaoxing 1
Southend 1
Springfield 1
Suzhou 1
Tappahannock 1
Tokyo 1
Villa Cuauhtemoc 1
Villa San Giovanni 1
Wexford 1
Totale 2.975
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Nome #
Maturazione dell’affinità anticorpale nel sistema del 2-fenil-5-ossazolone 96
A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping. 84
Characterisation of the SF/HGF gene promoter. 84
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes. 81
A G2/M cell cycle block in transformed cells by contact with normal neighbors. 78
Co-expression of the HGF/SF and c-met genes during early mouse embryongenesis precedes reciprocal expression in adjacent tissues during organogenesis 76
Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein. 75
An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. 74
Ingegneria degli anticorpi 73
Structural basis of affinity maturation of the TEPC15/Vkappa 45.1 anti-2-phenyl-5-oxazolone antibodies. 72
Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. 72
Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells. 71
Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. 71
Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit 69
Structural basis of hepatocyte growth factor/scatter factor and MET signalling. 69
Roles of Hepatocyte Growth Factor/Scatter Factor and the Met Receptor in the Early Development of the Metanephros. 69
Crystal structure of an engineered YopM-InlB hybrid protein 69
Met receptor agonist proteins 69
Hepatocyte growth factor/scatter factor and MET are involved in arterial repair and atherogenesis. 69
A role of HGF/SF in neural induction and its expression in Hensen's node during gastrulation. 67
Epithelial scatter factor and development of the chick embryonic axis. 66
Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor. 66
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans and improved activity in vivo. 65
Met, metastasis, motility and more. 64
Multimeric compounds of a kringle domain from the hepatocyte growth factor / scatter factor (hgf/sf) 64
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. 64
The sema domain. 63
A Novel Multipurpose Monoclonal Antibody for Evaluating Human c-Met Expression in Preclinical and Clinical Settings 62
X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB 60
The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans. 59
Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. 57
Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 57
Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis 57
Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells 56
HGF/SF inhibits junctional communication. 56
The effect of high-frequency random mutagenesis on in vitro protein evolution: a stuudy on TEM-1 beta-lactamase. 56
Maturazione dell’affinità anticorpale 56
A Mechanistic Basis for Converting a Growth-Factor Receptor Agonist to an Antagonist. 56
Isolation of high affinity human antibodies directly from large synthetic repertoires. 56
Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor. 55
Structural Basis of Affinity Maturation of Antibodies in the 2- Phenyl-5-Oxazolone System 55
Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach 54
Heparan sulphate-modified CD44 promotes hepatocyte grwoth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met 53
Mutation and selection during the secondary response to 2-phenyloxazolone. 53
Targeting MET in cancer: rationale and progress 53
Original and artificial antibodies. 53
Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes. 51
Scatter factor is a fibroblast-derived modulator of epithelial cell motility. 50
The structural repertoire of the human Vk domain. 50
Non-random features of the repertoire expressed by the members of one Vk gene family and V-J recombination. 50
Structural Basis of Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 50
Expression of a Cx43 deletion mutant in 3T3 A31 fibroblasts prevents PDGF-induced inhibition of cell communication and suppresses cell growth 49
Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB 49
One man and his molecule 48
Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain 47
Ligand-Mediated Dimerization of the Met Receptor Tyrosine Kinase by the Bacterial Invasion Protein InlB 46
Ingegnerizzazione di mAb per scopi teraupeutici 46
Interactions of hepatocyte growth factor / scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. 44
Diverse and potent activities of HGF/SF in skin wound repair. 44
Scatter factor/hepatocyte growth factor is essential for liver development. 42
Structural Basis of Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 42
A novel HGF/SF receptor (MET) agonist transiently delays the disease progression in an amyotrophic lateral sclerosis mouse model by promoting neuronal survival and dampening the immune dysregulation 41
Michael Stoker 1918–2013 40
Protein Engineered Variants of Hepatocyte Growth Factor/Scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver 40
Down regulation of scatter factor in MRC 5 fibroblasts by epithelial-derived cells. A model for scatter factor modulation. 40
Insights into the structure/function of HGF/SF from studies with individual domains. 39
Erratum: Targeting MET in cancer: Rationale and progress (Nature Reviews Cancer (2012) 12 (89-103)) 39
Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor-induced angiogenesis. 37
Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking 37
Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting 35
Generation and characterization of novel recombinant antihERG1 scFv antibodies for cancer molecular imaging 33
Structural basis for agonism and antagonism of hepatocyte growth factor 32
Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex 29
MODIFIED HGF-1K1 POLYPEPTIDE. 28
Engineering the NK1 fragment of HGF/SF as a MET receptor antagonist. 25
Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist 24
Hepatocyte growth factor/scatter factor (HGF/SF) accelerates angiogenesis in sponge implants in mice: Modulation by L- name and NS 398 24
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding 23
Non-Agonistic Bivalent Antibodies That Promote c-MET Degradation and Inhibit Tumor Growth and Others Specific for Tumor Related c-MET 23
Totale 4.301
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Categoria #
all - tutte 16.272
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.272
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020242 0 0 0 0 1 52 5 49 3 65 64 3
2020/2021516 61 51 24 50 0 64 6 68 26 75 68 23
2021/2022342 6 3 5 3 10 14 12 29 21 10 49 180
2022/20231.271 125 88 41 147 142 127 0 73 482 8 17 21
2023/2024320 38 55 18 21 43 69 9 38 2 8 10 9
2024/2025180 11 91 27 44 7 0 0 0 0 0 0 0
Totale 4.301