IRIS
GHERARDI, ERMANNO
 Distribuzione geografica
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Continente #
NA - Nord America 2.477
AS - Asia 1.859
EU - Europa 1.605
SA - Sud America 217
AF - Africa 18
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.182
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Nazione #
US - Stati Uniti d'America 2.443
CN - Cina 1.110
IE - Irlanda 370
SG - Singapore 368
UA - Ucraina 279
HK - Hong Kong 197
BR - Brasile 185
RU - Federazione Russa 173
FI - Finlandia 166
DE - Germania 165
SE - Svezia 134
IT - Italia 112
GB - Regno Unito 108
VN - Vietnam 74
FR - Francia 38
IN - India 31
CA - Canada 18
JP - Giappone 18
BE - Belgio 16
AR - Argentina 13
BD - Bangladesh 13
ES - Italia 9
IQ - Iraq 8
MX - Messico 8
NL - Olanda 8
AT - Austria 7
ID - Indonesia 7
PL - Polonia 7
CO - Colombia 5
SA - Arabia Saudita 5
ZA - Sudafrica 5
BO - Bolivia 4
KE - Kenya 4
LT - Lituania 4
TR - Turchia 4
CH - Svizzera 3
EC - Ecuador 3
NP - Nepal 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
CL - Cile 2
CR - Costa Rica 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
EG - Egitto 2
ET - Etiopia 2
EU - Europa 2
JO - Giordania 2
KG - Kirghizistan 2
KR - Corea 2
LU - Lussemburgo 2
NZ - Nuova Zelanda 2
OM - Oman 2
PA - Panama 2
PY - Paraguay 2
TT - Trinidad e Tobago 2
VE - Venezuela 2
AL - Albania 1
BH - Bahrain 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
IR - Iran 1
KH - Cambogia 1
KZ - Kazakistan 1
LB - Libano 1
LY - Libia 1
MN - Mongolia 1
MU - Mauritius 1
PH - Filippine 1
PK - Pakistan 1
TN - Tunisia 1
UY - Uruguay 1
Totale 6.182
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Città #
Chandler 512
Dublin 368
Jacksonville 307
Nanjing 292
Hong Kong 197
Ashburn 176
Singapore 172
Beijing 154
Boardman 127
Dallas 119
Nanchang 109
Princeton 79
Lawrence 78
Wilmington 77
Hebei 75
Ann Arbor 74
Shenyang 73
Changsha 66
Los Angeles 56
Medford 52
Jiaxing 45
Buffalo 43
Moscow 42
Tianjin 41
Milan 35
Hangzhou 30
Munich 27
Helsinki 26
Ho Chi Minh City 25
New York 25
Shanghai 24
São Paulo 22
Woodbridge 22
Norwalk 21
Verona 20
Pavia 19
Brussels 16
Hanoi 16
Chennai 13
Tokyo 13
Seattle 12
Kunming 11
Zhengzhou 10
Guangzhou 9
Phoenix 9
Rio de Janeiro 9
San Francisco 9
Council Bluffs 8
Santa Clara 8
Falls Church 7
Montreal 7
Redondo Beach 7
San Jose 7
Warsaw 7
Biên Hòa 6
Brooklyn 6
Jinan 6
London 6
Toronto 6
Atlanta 5
Boston 5
Brasília 5
Denver 5
Fairfield 5
Nuremberg 5
Orem 5
Poplar 5
The Dalles 5
Washington 5
Amsterdam 4
Auburn Hills 4
Baghdad 4
Curitiba 4
Haiphong 4
Nairobi 4
Pune 4
Recife 4
Shenzhen 4
Stockholm 4
Taizhou 4
Belo Horizonte 3
Bologna 3
Chicago 3
Cleveland 3
Cochabamba 3
Columbus 3
Cosenza 3
Leawood 3
Mexico City 3
New Delhi 3
Nürnberg 3
Porto Alegre 3
Prineville 3
Qingdao 3
Quito 3
Riyadh 3
Santa Luzia 3
Santo André 3
Tashkent 3
Toyonaka 3
Totale 3.992
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Nome #
Characterisation of the SF/HGF gene promoter. 123
Maturazione dell’affinità anticorpale nel sistema del 2-fenil-5-ossazolone 121
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes. 119
A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping. 115
Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. 111
Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein. 110
Co-expression of the HGF/SF and c-met genes during early mouse embryongenesis precedes reciprocal expression in adjacent tissues during organogenesis 110
Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain 108
A G2/M cell cycle block in transformed cells by contact with normal neighbors. 107
An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. 105
Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit 104
A role of HGF/SF in neural induction and its expression in Hensen's node during gastrulation. 104
Structural basis of hepatocyte growth factor/scatter factor and MET signalling. 101
Met receptor agonist proteins 100
Crystal structure of an engineered YopM-InlB hybrid protein 99
Ingegneria degli anticorpi 97
Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 95
Multimeric compounds of a kringle domain from the hepatocyte growth factor / scatter factor (hgf/sf) 95
Structural Basis of Affinity Maturation of Antibodies in the 2- Phenyl-5-Oxazolone System 95
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. 95
A Mechanistic Basis for Converting a Growth-Factor Receptor Agonist to an Antagonist. 94
A Novel Multipurpose Monoclonal Antibody for Evaluating Human c-Met Expression in Preclinical and Clinical Settings 93
A novel HGF/SF receptor (MET) agonist transiently delays the disease progression in an amyotrophic lateral sclerosis mouse model by promoting neuronal survival and dampening the immune dysregulation 93
Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells. 91
Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis 91
X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB 90
Roles of Hepatocyte Growth Factor/Scatter Factor and the Met Receptor in the Early Development of the Metanephros. 89
Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. 88
Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach 88
Hepatocyte growth factor/scatter factor and MET are involved in arterial repair and atherogenesis. 88
Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes. 86
The sema domain. 85
Structural basis of affinity maturation of the TEPC15/Vkappa 45.1 anti-2-phenyl-5-oxazolone antibodies. 83
Epithelial scatter factor and development of the chick embryonic axis. 81
Met, metastasis, motility and more. 81
Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor. 79
Ingegnerizzazione di mAb per scopi teraupeutici 79
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans and improved activity in vivo. 77
Mutation and selection during the secondary response to 2-phenyloxazolone. 74
The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans. 74
Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor. 73
Non-random features of the repertoire expressed by the members of one Vk gene family and V-J recombination. 73
Maturazione dell’affinità anticorpale 73
Isolation of high affinity human antibodies directly from large synthetic repertoires. 73
Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking 73
Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. 71
Heparan sulphate-modified CD44 promotes hepatocyte grwoth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met 71
Targeting MET in cancer: rationale and progress 71
Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells 70
Scatter factor is a fibroblast-derived modulator of epithelial cell motility. 70
HGF/SF inhibits junctional communication. 70
One man and his molecule 70
The effect of high-frequency random mutagenesis on in vitro protein evolution: a stuudy on TEM-1 beta-lactamase. 69
Generation and characterization of novel recombinant antihERG1 scFv antibodies for cancer molecular imaging 69
MODIFIED HGF-1K1 POLYPEPTIDE. 65
The structural repertoire of the human Vk domain. 64
Original and artificial antibodies. 64
Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB 63
Structural Basis of Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 62
Ligand-Mediated Dimerization of the Met Receptor Tyrosine Kinase by the Bacterial Invasion Protein InlB 62
Scatter factor/hepatocyte growth factor is essential for liver development. 62
Expression of a Cx43 deletion mutant in 3T3 A31 fibroblasts prevents PDGF-induced inhibition of cell communication and suppresses cell growth 61
Non-Agonistic Bivalent Antibodies That Promote c-MET Degradation and Inhibit Tumor Growth and Others Specific for Tumor Related c-MET 60
Michael Stoker 1918–2013 60
Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor-induced angiogenesis. 60
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding 59
Diverse and potent activities of HGF/SF in skin wound repair. 58
Insights into the structure/function of HGF/SF from studies with individual domains. 56
Structural Basis of Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System 56
Protein Engineered Variants of Hepatocyte Growth Factor/Scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver 56
Interactions of hepatocyte growth factor / scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. 55
Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist 54
Down regulation of scatter factor in MRC 5 fibroblasts by epithelial-derived cells. A model for scatter factor modulation. 53
Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting 52
Erratum: Targeting MET in cancer: Rationale and progress (Nature Reviews Cancer (2012) 12 (89-103)) 52
Structural basis for agonism and antagonism of hepatocyte growth factor 48
Engineering the NK1 fragment of HGF/SF as a MET receptor antagonist. 45
Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex 43
Hepatocyte growth factor/scatter factor (HGF/SF) accelerates angiogenesis in sponge implants in mice: Modulation by L- name and NS 398 32
Totale 6.216
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Categoria #
all - tutte 24.791
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.791
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021330 0 0 0 0 0 64 6 68 26 75 68 23
2021/2022342 6 3 5 3 10 14 12 29 21 10 49 180
2022/20231.271 125 88 41 147 142 127 0 73 482 8 17 21
2023/2024320 38 55 18 21 43 69 9 38 2 8 10 9
2024/2025903 11 91 27 44 11 40 13 61 229 26 93 257
2025/20261.192 183 164 234 255 259 97 0 0 0 0 0 0
Totale 6.216