IRIS
CETTA, GIUSEPPE
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 2.457
EU - Europa 2.080
AS - Asia 1.517
SA - Sud America 91
Continente sconosciuto - Info sul continente non disponibili 5
AF - Africa 3
OC - Oceania 2
Totale 6.155
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.425
CN - Cina 1.084
IE - Irlanda 550
UA - Ucraina 324
RU - Federazione Russa 272
FI - Finlandia 268
DE - Germania 205
HK - Hong Kong 194
SG - Singapore 180
IT - Italia 114
GB - Regno Unito 110
SE - Svezia 96
BR - Brasile 86
FR - Francia 42
BE - Belgio 35
CA - Canada 21
CZ - Repubblica Ceca 17
IR - Iran 17
NL - Olanda 11
IN - India 8
TR - Turchia 8
JP - Giappone 7
LT - Lituania 7
MX - Messico 7
RO - Romania 6
AT - Austria 5
PL - Polonia 5
VN - Vietnam 5
A2 - ???statistics.table.value.countryCode.A2??? 3
AR - Argentina 3
BD - Bangladesh 3
LV - Lettonia 3
AU - Australia 2
ES - Italia 2
JM - Giamaica 2
NP - Nepal 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BG - Bulgaria 1
BO - Bolivia 1
CH - Svizzera 1
CO - Colombia 1
CR - Costa Rica 1
EE - Estonia 1
ET - Etiopia 1
EU - Europa 1
GR - Grecia 1
HU - Ungheria 1
IQ - Iraq 1
MA - Marocco 1
MD - Moldavia 1
MU - Mauritius 1
PA - Panama 1
PK - Pakistan 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TM - Turkmenistan 1
TW - Taiwan 1
UZ - Uzbekistan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 6.155
Salva come PNG Salva come JPEG
Città #
Dublin 550
Chandler 505
Jacksonville 375
Nanjing 254
Beijing 216
Hong Kong 194
Ann Arbor 171
Ashburn 151
Boardman 141
Nanchang 110
Singapore 101
Lawrence 82
Princeton 82
Wilmington 81
Medford 80
Shenyang 77
Helsinki 74
Changsha 72
Hebei 65
Jiaxing 63
Shanghai 59
Hangzhou 57
Moscow 55
Woodbridge 54
Tianjin 50
Milan 47
Los Angeles 39
Munich 39
Brussels 35
Turku 32
Verona 26
Auburn Hills 22
New York 21
Washington 21
Houston 16
The Dalles 14
Norwalk 13
Chicago 12
Seattle 11
Dearborn 10
Falkenstein 10
Kunming 10
Pavia 9
Toronto 9
Ardabil 8
Brno 8
Dallas 8
Fairfield 7
Frankfurt am Main 7
London 7
Ningbo 7
Olomouc 7
Des Moines 6
Ottawa 6
Santa Clara 6
Jinan 5
Monmouth Junction 5
Rio de Janeiro 5
Stockholm 5
Tappahannock 5
Zhengzhou 5
Brooklyn 4
Rome 4
Sacramento 4
Tokyo 4
Warsaw 4
Boston 3
Curitiba 3
Detroit 3
Duncan 3
Falls Church 3
Lanzhou 3
Leawood 3
San Francisco 3
San Miguel de Allende 3
São Paulo 3
Vienna 3
Andover 2
Aracaju 2
Belo Horizonte 2
Florianópolis 2
Fuzhou 2
Guarulhos 2
Hanoi 2
Harbin 2
Istanbul 2
Kingston 2
Manchester 2
Montreal 2
Monza 2
Orange 2
Paris 2
Porto Alegre 2
Riga 2
Salvador 2
St Petersburg 2
Teano 2
Vĩnh Tường 2
Winnipeg 2
Abaetetuba 1
Totale 4.320
Salva come PNG Salva come JPEG
Nome #
Molecular characterisation of six patients with prolidase deficiency: identification of the first small duplication in the prolidase gene and of a mutation generating symptomatic and asymptomatic outcomes within the same family. 113
Micellar electrokinetic chromatography for analyzing active site specificity of Pseudomonas aeruginosa elastase. 112
Cartilage histogenesis in a murine model of chondrodysplasia 111
Adesion proteins in CHO cells. 105
Effects of lactitol compared to polyethylene glicol-3350 on fecal short chain fatty acids and microflora in old patients with idiopathic chronic constipation. 105
In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation. 104
Biodegradable microspheres for prolidase delivery to human cultured fibroblasts 103
Separation of closely related peptide substrates of human proteinases by micellar electrokinetic chromatography with anionic and nonionic surfactants. 100
Differential expression of both extracellular and intracellular proteins is involved in the lethal or nonlethal phenotypic variation of BrtlIV, a murine model for osteogenesis imperfecta 98
Sequencing prolidase from pig kidney using multiple enzymatic digestion and LC-ESI-QTOF 98
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 97
Investigation on transcellular delivery of active enzyme relased from PLGA microspheres 96
A de novo G to T transversion in a pro-a1(I) collagen gene for a moderate case of osteogenesis imperfecta. Substitution of cysteine for glycine 178 in the triple helical domain. 95
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies. 94
Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts 94
Deposition of mutant type I collagen in the extracellular matrix of cultured dermal fibroblasts in osteogenesis imperfecta. 93
Intracellular delivery of liposome-encapsulated prolidase in cultured fibroblasts from prolidase-deficient patients 92
Capillary electrophoresis with laser-induced fluorescence detection as a novel sensitive approach for the analysis of desmosines in real samples. 91
Effect of enamel matrix derivative on human periodontal fibroblasts: proliferation, morphology and root surface colonization. An in vitro study 91
Diagnosis of late-infantile neuronal ceroid lipofuscinosis: a new sensitive method to assay lysosomal pepstatin-insensitive proteinase activity in human and animal specimens by capillary electrophoresis. 89
Alpha1-antitrypsin in serum determined by capillary isoelectric focusing 89
Direct monitoring of prolidase activity in cultured skin fibroblasts using capillary electrophoresis 88
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship. 87
Insights from a transgenic mouse model on the role of SLC26A2 in health and disease. 87
Deficient expression of the small proteoglycan decorin in a case of severe/lethal osteogenesis imperfecta. 87
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency. 85
A 931 + 2T-->C transition in one COL1A2 allele causes exon 16 skipping in PRO alpha 2(I) mRNA and produces moderately severe OI. 85
Enzyme replacement as a new therapy for prolidase deficiency 84
Anomalous cysteine in type I collagen. Localisation by chemical cleavage of the protein using 2-nitro-5-thiocyanobenzoic acid and by mismatch analysis of cDNA heteroduplexes. 84
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 83
Use of capillary zone electrophoresis for analysis of imidodipeptides in urine of prolidase-deficient patients. 83
Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts 82
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 82
Intracellular release of a liposome-incapsulated biologically active protein 81
A base substitution at IVS-19 3'-end splice junction causes exon 20 skipping in pro alpha 2(I) collagen mRNA and produces mild osteogenesis imperfecta. 81
Phenotypic variability and abnormal type I collagen unstable at body temperature in a family with mild dominant osteogenesis imperfecta. 79
Micellar electrokinetic chromatography for the determination of urinary desmosine and isodesmosine in patients affected by chronic obstructive pulmonary disease 78
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations 77
Micellar electrokinetic chromatographic and capillary zone electrophoretic methods for screening urinary biomarkers of human disorders: a critical review of the state-of-the-art. 77
Micellar electrokinetic chromatography: a convenient alternative to colorimetric and high performance liquid chromatographic detection for monitoring protease activity. 76
Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures. 76
Severe nonlethal osteogenesis imperfecta: biochemical heterogeneity. 75
N-benzyloxycarbonyl-L-proline: an in vitro inhibitor of prolidase. 75
Inhibition of human neutrophil elastase by erythromycin andflurythromycin, two macrolide antibiotics. 74
Stability of type I collagen peptide trimers. 74
High levels of desmosines in urine and plasma of patients with pseudoxanthoma elasticum. 74
The role of emerging techniques in the investigation of prolidase deficiency: from diagnosis to the development of a possible therapeutical approach 73
Direct monitoring of prolidase activity in cultured skin fibroblasts using capillary electrophoresis. 73
Extracellular matrix deposition in cultured dermal fibroblasts from four probands affected by osteogenesis imperfecta. 72
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 72
Type I collagen CNBr peptides: species and behavior in solution 69
Prolidase deficiency in two siblings with chronic leg ulcerations. Clinical, biochemical, and morphologic aspects. 69
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 68
Activity of different proteases in a complex mixture and 'in vitro' study of their reciprocal interferences by micellar electrokinetic chromatography. 67
Complete resolution of imidodipeptide mixtures in urine of prolidase-deficient patients using micellar electrokinetic chromatography. 67
Type I procollagen in the severe non-lethal form of osteogenesis imperfecta. Defective pro-alpha 1(I) chains in a patient with abnormal proteoglycan metabolism and mineral deposits in the dermis. 66
Defective proteoglycan sulfation of the growth plate zones causes reduced chondrocyte proliferation via an altered Indian hedgehog signalling 64
Osteogenesis imperfecta and type I collagen mutations. A lethal variant caused by a Gly910->Ala substitution in the a1(I) chain. 63
Phenotypic comparison of an osteogenesis imperfecta type IV proband with a de novo alpha2(I) Gly922 --> Ser substitution in type I collagen and an unrelated patient with an identical mutation. 63
Capillary electrophoresis as a modern tool for determining proteolytic activities in purified specimens and in real samples 63
Evaluation of the TiMo12Zr6Fe2 alloy for orthopaedic implants: in vitro biocompatibility study by using primary human fibroblasts and osteoblasts 61
Mild, late-onset prolidase deficiency: another Italian case. 61
A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype 61
Possible role of overglycosylation in the type I collagen triple helical domain in the molecular pathogenesis of osteogenesis imperfecta. 59
Effect of different surfactants on the separation by micellar electrokinetic chromatography of a complex mixture of dipeptides in urine of prolidase-deficient patients. 59
Localization of a structural defect in type I procollagen in a patient affected with the severe non-lethal form of Osteogenesis imperfecta. 59
Therapeutic apheresis exchange in two patients with prolidase deficiency 58
Undersulfation of proteoglycans synthesized by chondrocytes from a patient with achondrogenesis type 1B homozygous for a Leu483Pro substitution in the diastrophic dysplasia sulfate transporter 57
Diastrophic dysplasia sulfate transporter (DTDST) gene is not involved in pseudodiastrophic dysplasia 56
Simultaneous determination of Pseudomonas aeruginosa elastase, human leukocyte elastase and cathepsin G activities by micellar electrokinetic chromatography 56
Gly85 to Val substitution in proa1(I) chain causes mild osteogenesis imperfecta and introduces a susceptibility to protease digestion. 54
Severe (type III) osteogenesis imperfecta due to glycine substitutions in the central domain of the collagen triple helix. 54
Proteoglycan modifications in cultured Osteogenesis Imperfecta skin fibroblasts. 54
Serum type I and type III procollagen peptide levels in sarcoidosis. 51
Proteoglycan sulfation in cartilage and cell cultures from patients with sulfate transporter chondrodysplasias: relationship to clinical severity and indications on the role of intracellular sulfate production 50
In vitro proteoglycan sulfation derived from sulfhydryl compounds in sulfate transporter chondrodysplasias 50
Undersulfation of cartilage proteoglycans ex vivo and increased contribution of amino acid sulfur to sulfation in vitro in McAlister dysplasia/atelosteogenesis type 2 49
Mild dominant osteogenesis imperfecta with intrafamilial variability: the cause is a serine for glycine a1(I) 901 substitution in a type-I collagen gene. 47
Moderately severe osteogenesis imperfecta: biochemical studies showing variable defect localization in the triple-helical domain of type I collagen. 46
Relationship between changes in alveolar surfactant levels and lung defence mechanisms. 44
Paternal mosaicism for a COL1A1 dominant mutation (alpha 1 Ser-415) causes recurrent osteogenesis imperfecta. 42
Prolidase deficiency: biochemical study of erythrocyte and skin fibroblast prolidase activity in Italian patients. 38
Totale 6.199
Salva come PNG Salva come JPEG
Categoria #
all - tutte 24.800
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.800
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201 0 0 0 0 0 0 0 0 0 0 0 1
2020/2021560 75 54 14 60 4 66 9 93 13 84 73 15
2021/2022417 7 12 18 8 10 7 11 29 17 12 67 219
2022/20231.445 129 142 13 113 161 123 5 61 622 20 42 14
2023/2024504 72 90 31 48 51 104 26 29 9 18 17 9
2024/20251.278 40 97 46 34 37 63 69 33 360 39 197 263
Totale 6.199