IRIS
CETTA, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 2.297
EU - Europa 1.709
AS - Asia 1.165
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
AF - Africa 1
SA - Sud America 1
Totale 5.179
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Nazione #
US - Stati Uniti d'America 2.277
CN - Cina 1.019
IE - Irlanda 550
UA - Ucraina 321
FI - Finlandia 233
DE - Germania 169
SG - Singapore 119
IT - Italia 111
GB - Regno Unito 106
SE - Svezia 91
FR - Francia 40
BE - Belgio 35
CA - Canada 17
IR - Iran 17
RU - Federazione Russa 17
CZ - Repubblica Ceca 10
NL - Olanda 9
LT - Lituania 6
RO - Romania 6
IN - India 5
JP - Giappone 4
A2 - ???statistics.table.value.countryCode.A2??? 3
MX - Messico 3
AU - Australia 2
BO - Bolivia 1
CH - Svizzera 1
EU - Europa 1
HU - Ungheria 1
LV - Lettonia 1
MD - Moldavia 1
MU - Mauritius 1
PL - Polonia 1
TR - Turchia 1
Totale 5.179
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Città #
Dublin 550
Chandler 505
Jacksonville 375
Nanjing 254
Ann Arbor 171
Beijing 163
Ashburn 146
Boardman 141
Nanchang 110
Singapore 91
Lawrence 82
Princeton 82
Wilmington 81
Medford 80
Shenyang 77
Changsha 72
Helsinki 71
Hebei 65
Jiaxing 63
Shanghai 59
Hangzhou 57
Woodbridge 54
Tianjin 50
Milan 47
Brussels 35
Verona 26
Auburn Hills 22
Los Angeles 22
Washington 20
Houston 16
New York 16
Munich 15
Norwalk 13
Dearborn 10
Kunming 10
Chicago 9
Seattle 9
Toronto 9
Ardabil 8
Brno 8
Fairfield 7
Pavia 7
Des Moines 6
Falkenstein 6
Frankfurt am Main 6
Ningbo 6
Ottawa 6
Dallas 5
Jinan 5
London 5
Monmouth Junction 5
Tappahannock 5
Zhengzhou 5
Sacramento 4
Detroit 3
Duncan 3
Falls Church 3
Lanzhou 3
Leawood 3
Rome 3
San Miguel de Allende 3
Andover 2
Fuzhou 2
Monza 2
Orange 2
St Petersburg 2
Teano 2
Winnipeg 2
Augusta 1
Austin 1
Berlin 1
Brdo 1
Budapest 1
Changchun 1
Chisinau 1
Cupertino 1
Groningen 1
Gunzenhausen 1
Harbin 1
Henderson 1
Jalandhar 1
Jiaozuo 1
Kish 1
Melbourne 1
Montereale Valcellina 1
Moscow 1
Ornavasso 1
Piscataway 1
Pitesti 1
Polska 1
Prague 1
Pune 1
Qingdao 1
Redwood City 1
Rockville 1
Santa Clara 1
Shiraz 1
Simi Valley 1
Taganrog 1
Taiyuan 1
Totale 3.839
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Nome #
Micellar electrokinetic chromatography for analyzing active site specificity of Pseudomonas aeruginosa elastase. 96
Molecular characterisation of six patients with prolidase deficiency: identification of the first small duplication in the prolidase gene and of a mutation generating symptomatic and asymptomatic outcomes within the same family. 95
In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation. 93
Cartilage histogenesis in a murine model of chondrodysplasia 92
Separation of closely related peptide substrates of human proteinases by micellar electrokinetic chromatography with anionic and nonionic surfactants. 91
Adesion proteins in CHO cells. 91
Effects of lactitol compared to polyethylene glicol-3350 on fecal short chain fatty acids and microflora in old patients with idiopathic chronic constipation. 88
Biodegradable microspheres for prolidase delivery to human cultured fibroblasts 88
A de novo G to T transversion in a pro-a1(I) collagen gene for a moderate case of osteogenesis imperfecta. Substitution of cysteine for glycine 178 in the triple helical domain. 87
Sequencing prolidase from pig kidney using multiple enzymatic digestion and LC-ESI-QTOF 85
Deposition of mutant type I collagen in the extracellular matrix of cultured dermal fibroblasts in osteogenesis imperfecta. 83
Mutation analysis of five new patients affected by prolidase deficiency: the lack of enzyme activity causes necrosis-like cell death in cultured fibroblasts 83
Effect of enamel matrix derivative on human periodontal fibroblasts: proliferation, morphology and root surface colonization. An in vitro study 82
Differential expression of both extracellular and intracellular proteins is involved in the lethal or nonlethal phenotypic variation of BrtlIV, a murine model for osteogenesis imperfecta 81
Investigation on transcellular delivery of active enzyme relased from PLGA microspheres 80
Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies. 80
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 80
Diagnosis of late-infantile neuronal ceroid lipofuscinosis: a new sensitive method to assay lysosomal pepstatin-insensitive proteinase activity in human and animal specimens by capillary electrophoresis. 77
Capillary electrophoresis with laser-induced fluorescence detection as a novel sensitive approach for the analysis of desmosines in real samples. 76
Use of capillary zone electrophoresis for analysis of imidodipeptides in urine of prolidase-deficient patients. 76
Direct monitoring of prolidase activity in cultured skin fibroblasts using capillary electrophoresis 75
Characterization of a new PEPD allele causing prolidase deficiency in two unrelated patients: natural-occurrent mutations as a tool to investigate structure-function relationship. 75
A 931 + 2T-->C transition in one COL1A2 allele causes exon 16 skipping in PRO alpha 2(I) mRNA and produces moderately severe OI. 75
Intracellular delivery of liposome-encapsulated prolidase in cultured fibroblasts from prolidase-deficient patients 74
Enzyme replacement as a new therapy for prolidase deficiency 73
Deficient expression of the small proteoglycan decorin in a case of severe/lethal osteogenesis imperfecta. 73
Micellar electrokinetic chromatography for the determination of urinary desmosine and isodesmosine in patients affected by chronic obstructive pulmonary disease 72
Alpha1-antitrypsin in serum determined by capillary isoelectric focusing 72
Rapid detection of ornithine transcarbamylase activity by micellar electrokinetic chromatography. 71
Anomalous cysteine in type I collagen. Localisation by chemical cleavage of the protein using 2-nitro-5-thiocyanobenzoic acid and by mismatch analysis of cDNA heteroduplexes. 71
Insights from a transgenic mouse model on the role of SLC26A2 in health and disease. 70
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency. 68
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 68
Phenotypic variability and abnormal type I collagen unstable at body temperature in a family with mild dominant osteogenesis imperfecta. 68
Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts 67
Intracellular release of a liposome-incapsulated biologically active protein 66
The role of emerging techniques in the investigation of prolidase deficiency: from diagnosis to the development of a possible therapeutical approach 66
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations 66
Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures. 66
A base substitution at IVS-19 3'-end splice junction causes exon 20 skipping in pro alpha 2(I) collagen mRNA and produces mild osteogenesis imperfecta. 66
Micellar electrokinetic chromatography: a convenient alternative to colorimetric and high performance liquid chromatographic detection for monitoring protease activity. 65
Stability of type I collagen peptide trimers. 64
Severe nonlethal osteogenesis imperfecta: biochemical heterogeneity. 64
High levels of desmosines in urine and plasma of patients with pseudoxanthoma elasticum. 63
N-benzyloxycarbonyl-L-proline: an in vitro inhibitor of prolidase. 63
Direct monitoring of prolidase activity in cultured skin fibroblasts using capillary electrophoresis. 62
Extracellular matrix deposition in cultured dermal fibroblasts from four probands affected by osteogenesis imperfecta. 61
Inhibition of human neutrophil elastase by erythromycin andflurythromycin, two macrolide antibiotics. 59
Micellar electrokinetic chromatographic and capillary zone electrophoretic methods for screening urinary biomarkers of human disorders: a critical review of the state-of-the-art. 58
Micellar electrokinetic chromatography as a complementary method to sodium dodecyl sulfate-polyacrylamide gel electrophoresis for studying limited proteolysis of proteins. 58
Phenotypic comparison of an osteogenesis imperfecta type IV proband with a de novo alpha2(I) Gly922 --> Ser substitution in type I collagen and an unrelated patient with an identical mutation. 57
Activity of different proteases in a complex mixture and 'in vitro' study of their reciprocal interferences by micellar electrokinetic chromatography. 57
Type I collagen CNBr peptides: species and behavior in solution 56
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 56
Osteogenesis imperfecta and type I collagen mutations. A lethal variant caused by a Gly910->Ala substitution in the a1(I) chain. 54
Capillary electrophoresis as a modern tool for determining proteolytic activities in purified specimens and in real samples 54
Possible role of overglycosylation in the type I collagen triple helical domain in the molecular pathogenesis of osteogenesis imperfecta. 52
Prolidase deficiency in two siblings with chronic leg ulcerations. Clinical, biochemical, and morphologic aspects. 52
Type I procollagen in the severe non-lethal form of osteogenesis imperfecta. Defective pro-alpha 1(I) chains in a patient with abnormal proteoglycan metabolism and mineral deposits in the dermis. 52
Diastrophic dysplasia sulfate transporter (DTDST) gene is not involved in pseudodiastrophic dysplasia 51
Evaluation of the TiMo12Zr6Fe2 alloy for orthopaedic implants: in vitro biocompatibility study by using primary human fibroblasts and osteoblasts 51
Complete resolution of imidodipeptide mixtures in urine of prolidase-deficient patients using micellar electrokinetic chromatography. 51
Defective proteoglycan sulfation of the growth plate zones causes reduced chondrocyte proliferation via an altered Indian hedgehog signalling 51
Undersulfation of proteoglycans synthesized by chondrocytes from a patient with achondrogenesis type 1B homozygous for a Leu483Pro substitution in the diastrophic dysplasia sulfate transporter 50
Effect of different surfactants on the separation by micellar electrokinetic chromatography of a complex mixture of dipeptides in urine of prolidase-deficient patients. 49
Severe (type III) osteogenesis imperfecta due to glycine substitutions in the central domain of the collagen triple helix. 49
Gly85 to Val substitution in proa1(I) chain causes mild osteogenesis imperfecta and introduces a susceptibility to protease digestion. 48
Mild, late-onset prolidase deficiency: another Italian case. 48
Therapeutic apheresis exchange in two patients with prolidase deficiency 47
A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype 47
Simultaneous determination of Pseudomonas aeruginosa elastase, human leukocyte elastase and cathepsin G activities by micellar electrokinetic chromatography 46
Localization of a structural defect in type I procollagen in a patient affected with the severe non-lethal form of Osteogenesis imperfecta. 46
Proteoglycan sulfation in cartilage and cell cultures from patients with sulfate transporter chondrodysplasias: relationship to clinical severity and indications on the role of intracellular sulfate production 44
Proteoglycan modifications in cultured Osteogenesis Imperfecta skin fibroblasts. 40
Mild dominant osteogenesis imperfecta with intrafamilial variability: the cause is a serine for glycine a1(I) 901 substitution in a type-I collagen gene. 40
In vitro proteoglycan sulfation derived from sulfhydryl compounds in sulfate transporter chondrodysplasias 40
Undersulfation of cartilage proteoglycans ex vivo and increased contribution of amino acid sulfur to sulfation in vitro in McAlister dysplasia/atelosteogenesis type 2 40
Serum type I and type III procollagen peptide levels in sarcoidosis. 39
Moderately severe osteogenesis imperfecta: biochemical studies showing variable defect localization in the triple-helical domain of type I collagen. 36
Paternal mosaicism for a COL1A1 dominant mutation (alpha 1 Ser-415) causes recurrent osteogenesis imperfecta. 34
Relationship between changes in alveolar surfactant levels and lung defence mechanisms. 34
Prolidase deficiency: biochemical study of erythrocyte and skin fibroblast prolidase activity in Italian patients. 29
Totale 5.223
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Categoria #
all - tutte 20.097
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.097
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020381 0 0 0 0 0 59 14 72 7 117 111 1
2020/2021560 75 54 14 60 4 66 9 93 13 84 73 15
2021/2022417 7 12 18 8 10 7 11 29 17 12 67 219
2022/20231.445 129 142 13 113 161 123 5 61 622 20 42 14
2023/2024504 72 90 31 48 51 104 26 29 9 18 17 9
2024/2025302 40 97 46 34 37 48 0 0 0 0 0 0
Totale 5.223