BARTOLUCCI, ROBERTA
BARTOLUCCI, ROBERTA
DIPARTIMENTO DI INGEGNERIA INDUSTRIALE E DELL'INFORMAZIONE
A clinical trial simulator to predict the effect of an adaptive dosing regimen of an investigated compound on platelets, white blood cells and haematocrit in patients with Polycythemia Vera
2022-01-01 Tosca, E. M.; Bartolucci, R.; Castellano, S.; Fiorentini, F.; Manzoni, S.; Di Tollo, S.; Caserini, M.; Rocchetti, M.; Bettica, P.; Magni, P.
A genetic algorithm for covariate selection
2021-01-01 Bartolucci, R.; Tosca, E. M.; Magni, P.
A PBPK model for the study of Azathioprine pharmacokinetics in rats and prediction in humans
2018-01-01 Bartolucci, R.; Melillo, N.; Magni, P.
A Population Pharmacokinetic Model of Macitentan and Its Active Metabolite Aprocitentan in Healthy Volunteers and Patients with Pulmonary Arterial Hypertension
2021-01-01 Bartolucci, R.; Dosne, A.; Csonka, D.; Perez-Ruixo, J. J.; Magni, P.; Poggesi, I.
Application of Artificial Neural Networks to Predict the Intrinsic Solubility of Drug-Like Molecules
2021-01-01 Tosca, E. M.; Bartolucci, R.; Magni, P.
Artificial intelligence and machine learning: just a hype or a new opportunity for pharmacometrics?
2019-01-01 Bartolucci, R.; Grandoni, S.; Melillo, N.; Nicora, G.; Sauta, E.; Tosca, E. M.; Magni, P.
Development of a genetic algorithm for covariate analysis in population pharmacokinetic models
2021-01-01 Bartolucci, R.; Masciale, G.; Tosca, E. M.; Magni, P.
Development of a PBPK model for the study of Azathioprine pharmacokinetics in rats and translation to humans
2018-01-01 Bartolucci, Roberta; Melillo, N.; Magni, P.
Evaluation of software tools for Bayesian estimation on population models:an update based on current software versions
2018-01-01 Bartolucci, R.; Lavezzi, S. M.; Tosca, E. M.; Melillo, N.; Grandoni, S.; Borella, E.; Pasotti, L.; De Nicolao, G.; Magni, P.
Facing the limits of the genetic algorithms for covariate selection
2022-01-01 Ronchi, D.; Tosca, E. M.; Ravasi, I.; Bartolucci, R.; Magni, P.
Go beyond the limits of genetic algorithm in daily covariate selection practice
2023-01-01 Ronchi, D.; Tosca, E. M.; Bartolucci, R.; Magni, P.
How Modelling and Simulations combined with Artificial Intelligence can improve Precision Dosing
2022-01-01 De Carlo, A.; Tosca, E. M.; Bartolucci, R.; Castellano, S.; Fiorentini, F.; Manzoni, S.; Di Tollo, S.; Caserini, M.; Rocchetti, M.; Bettica, P.; Magni, P.
Modeling approaches for reducing safety-related attrition in drug discovery and development: a review on myelotoxicity, immunotoxicity, cardiovascular toxicity, and liver toxicity
2021-01-01 Tosca, E. M.; Bartolucci, R.; Magni, P.; Poggesi, I.
Optimal design in pediatric clinical trials: theory and application to the macitentan case study
2021-02-22 Bartolucci, Roberta
Optimal design of paediatric clinical trials: the Macitentan case study
2019-01-01 Bartolucci, R.; Magni, P.
Optimization of the sampling strategy for pediatric clinical trials: the importance of prior information
2021-01-01 Bartolucci, R.; Magni, P.
PKPD modelling of MEN1611 anti-tumor effect in xenograft models to predict efficacy threshold concentrations in HER2-positive advanced or metastatic breast cancer patient population
2021-01-01 Tosca, E. M.; Borella, E.; Piana, C.; Fornari, C.; Bartolucci, R.; Mazzei, P.; Capriati, A.; Merlino, G.; Capano, S.; Laurent, D.; Pellacani, A.; Magni, P.
Predicting Aqueous and Intrinsic Solubility of Pharmaceutical Molecules with Neural Networks
2020-01-01 Melillo, N.; Podrecca, C.; Bartolucci, R.; Magni, P.
Whole-body PBPK model for a translational study of Azathioprine pharmacokinetics
2018-01-01 Bartolucci, Roberta; Melillo, N.; Magni, P.