MARRA, ANNAMARIA
MARRA, ANNAMARIA
DIPARTIMENTO DI SCIENZE DEL FARMACO
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist
2014-01-01 Rossi, Daniela; Marra, Annamaria; Erik, Laurini; Sabrina, Pricl; Dirk, Schepmann; Bernhard, Wuensch; Peviani, Marco; Curti, Daniela; Collina, Simona
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction?
2015-01-01 Rossi, Daniela; Marra, Annamaria; Rui, Marta; Erik, Laurini; Maurizio, Fermeglia; Sabrina, Pricl; Dirk, Schepmann; Bernhard, Wuensch; Peviani, Marco; Curti, Daniela; Collina, Simona
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor
2014-01-01 Marra, Annamaria; Erik, Laurini; Rossi, Daniela; Azzolina, Ornella; Sabrina, Pricl; Collina, Simona
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach
2013-01-01 Rossi, Daniela; Marra, Annamaria; Gaggeri, RAFFAELLA FRANCESCA; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Govoni, Stefano; Laurini, E.; Pricl, S.; Vasile, F.; Alberti, E.; Potenza, D.; Collina, Simona
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer
2019-01-01 Tesei, A.; Cortesi, M.; Pignatta, S.; Arienti, C.; Massimo Dondio, G.; Bigogno, C.; Malacrida, A.; Miloso, M.; Meregalli, C.; Chiorazzi, A.; Carozzi, V.; Cavaletti, G.; Rui, M.; Marra, A.; Rossi, D.; Collina, S.
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands
2015-01-01 Rossi, Daniela; Talman, V.; Gennäs, G. B. A.; Marra, Annamaria; Picconi, Pietro; Nasti, Rita; Serra, Massimo; Ann, J.; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Tuominen, R. K.; Yli Kauhaluoma, J.; Lee, J.; Collina, Simona
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain
2015-01-01 Nasti, Rita; Marra, Annamaria; Boije Gennäs, G; Talaman, V; Yli Kauhaluoma, J; Tuominen, R. K; Lee, J; Rossi, Daniela; Collina, Simona
Chemical, pharmacological and in vivo pharmacokinetic studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists
2015-01-01 Marra, Annamaria; Rossi, Daniela; Peviani, Marco; Cavaletti, G; Dondio, G; Curti, Daniela; Collina, Simona
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists.
2013-01-01 Rossi, Daniela; Pedrali, Alice; Gaggeri, RAFFAELLA FRANCESCA; Marra, Annamaria; Pignataro, L; Laurini, E; Dal Col, V; Fermeglia, M; Pricl, S; Schepmann, D; Wuensch, B; Peviani, Marco; Curti, Daniela; Collina, Simona
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.
2016-01-01 Marra, Annamaria; Rossi, Daniela; Maggi, Lauretta; Corana, Federica; Mannucci, Barbara; Peviani, Marco; Curti, Daniela; Collina, Simona
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy
2016-01-01 Rossi, Daniela; Nasti, Rita; Marra, Annamaria; Meneghini, Silvia; Mazzeo, G.; Longhi, G.; Memo, M.; Cosimelli, B.; Greco, G.; Novellino, E.; Da Settimo, F.; Martini, C.; Taliani, S.; Abbate, S.; Collina, Simona
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.
2013-01-01 Rossi, Daniela; Marra, Annamaria; P., Picconi; Serra, Massimo; Catenacci, Laura; Sorrenti, MILENA LILLINA; E., Laurini; M., Fermeglia; S., Pricl; S., Brambilla; N., Almirante; Peviani, Marco; Curti, Daniela; Collina, Simona
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent
2015-01-01 Marra, Annamaria; Rossi, Daniela; Dondio, G; Bigogno, C; Canta, A; Oggioni, N; Cavaletti, G; Curti, Daniela; Collina, Simona
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA
2013-01-01 Tripodo, Giuseppe; Maggi, Lauretta; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Marra, Annamaria; Rossi, Daniela; Collina, Simona
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment
2016-01-01 Rui, Marta; Marra, Annamaria; Pace, V.; Juza, M.; Rossi, Daniela; Collina, Simona
On the study of stereoselectivity in the ligand - Sigma1 receptor interaction.
2015-01-01 Rui, Marta; Marra, Annamaria; Rossi, Daniela; Lurini, E; Pricl, S; Collina, Simona
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106
2017-01-01 Rui, Marta; Rossi, Daniela; Marra, Annamaria; Dondio, Giulio; Tesei, A.; Cortesi, Michela; Collina, Simona
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers
2024-01-01 Listro, Roberta; Marra, Annamaria; Cavalloro, Valeria; Rossino, Giacomo; Linciano, Pasquale; Rossi, Daniela; Casali, Emanuele; De Amici, Marco; Mazzeo, Giuseppe; Longhi, Giovanna; Fusè, Marco; Dondio, Giulio; Pellavio, Giorgia; Laforenza, Umberto; Schepmann, Dirk; Wünsch, Bernhard; Collina, Simona
Sigma receptor modulators: a patent review.
2013-01-01 Collina, Simona; Gaggeri, RAFFAELLA FRANCESCA; Marra, Annamaria; Bassi, A; Negrinotti, Sara; Negri, Francesca; Rossi, Daniela
Sigma Receptors: Novel Targets For The Treatment Of Highly Malignant Tumors
2017-01-01 Cortesi, Michela; Pignatta, Sara; Collina, Simona; Rui, Marta; Marra, Annamaria; Tosatto, Luigino; Bartolini, Daniela; Nigrisoli, Evandro; Arienti, Andrea Rocca Alice Zamagni Chiara; Zanoni, Michele; Tesei, Anna
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist | 1-gen-2014 | Rossi, Daniela; Marra, Annamaria; Erik, Laurini; Sabrina, Pricl; Dirk, Schepmann; Bernhard, Wuensch; Peviani, Marco; Curti, Daniela; Collina, Simona | |
| A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? | 1-gen-2015 | Rossi, Daniela; Marra, Annamaria; Rui, Marta; Erik, Laurini; Maurizio, Fermeglia; Sabrina, Pricl; Dirk, Schepmann; Bernhard, Wuensch; Peviani, Marco; Curti, Daniela; Collina, Simona | |
| A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor | 1-gen-2014 | Marra, Annamaria; Erik, Laurini; Rossi, Daniela; Azzolina, Ornella; Sabrina, Pricl; Collina, Simona | |
| A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach | 1-gen-2013 | Rossi, Daniela; Marra, Annamaria; Gaggeri, RAFFAELLA FRANCESCA; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Govoni, Stefano; Laurini, E.; Pricl, S.; Vasile, F.; Alberti, E.; Potenza, D.; Collina, Simona | |
| Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer | 1-gen-2019 | Tesei, A.; Cortesi, M.; Pignatta, S.; Arienti, C.; Massimo Dondio, G.; Bigogno, C.; Malacrida, A.; Miloso, M.; Meregalli, C.; Chiorazzi, A.; Carozzi, V.; Cavaletti, G.; Rui, M.; Marra, A.; Rossi, D.; Collina, S. | |
| Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands | 1-gen-2015 | Rossi, Daniela; Talman, V.; Gennäs, G. B. A.; Marra, Annamaria; Picconi, Pietro; Nasti, Rita; Serra, Massimo; Ann, J.; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Tuominen, R. K.; Yli Kauhaluoma, J.; Lee, J.; Collina, Simona | |
| Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain | 1-gen-2015 | Nasti, Rita; Marra, Annamaria; Boije Gennäs, G; Talaman, V; Yli Kauhaluoma, J; Tuominen, R. K; Lee, J; Rossi, Daniela; Collina, Simona | |
| Chemical, pharmacological and in vivo pharmacokinetic studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists | 1-gen-2015 | Marra, Annamaria; Rossi, Daniela; Peviani, Marco; Cavaletti, G; Dondio, G; Curti, Daniela; Collina, Simona | |
| Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. | 1-gen-2013 | Rossi, Daniela; Pedrali, Alice; Gaggeri, RAFFAELLA FRANCESCA; Marra, Annamaria; Pignataro, L; Laurini, E; Dal Col, V; Fermeglia, M; Pricl, S; Schepmann, D; Wuensch, B; Peviani, Marco; Curti, Daniela; Collina, Simona | |
| Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. | 1-gen-2016 | Marra, Annamaria; Rossi, Daniela; Maggi, Lauretta; Corana, Federica; Mannucci, Barbara; Peviani, Marco; Curti, Daniela; Collina, Simona | |
| Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy | 1-gen-2016 | Rossi, Daniela; Nasti, Rita; Marra, Annamaria; Meneghini, Silvia; Mazzeo, G.; Longhi, G.; Memo, M.; Cosimelli, B.; Greco, G.; Novellino, E.; Da Settimo, F.; Martini, C.; Taliani, S.; Abbate, S.; Collina, Simona | |
| Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. | 1-gen-2013 | Rossi, Daniela; Marra, Annamaria; P., Picconi; Serra, Massimo; Catenacci, Laura; Sorrenti, MILENA LILLINA; E., Laurini; M., Fermeglia; S., Pricl; S., Brambilla; N., Almirante; Peviani, Marco; Curti, Daniela; Collina, Simona | |
| In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent | 1-gen-2015 | Marra, Annamaria; Rossi, Daniela; Dondio, G; Bigogno, C; Canta, A; Oggioni, N; Cavaletti, G; Curti, Daniela; Collina, Simona | |
| New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA | 1-gen-2013 | Tripodo, Giuseppe; Maggi, Lauretta; Amadio, Marialaura; Pascale, ALESSIA ANGELA; Marra, Annamaria; Rossi, Daniela; Collina, Simona | |
| Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment | 1-gen-2016 | Rui, Marta; Marra, Annamaria; Pace, V.; Juza, M.; Rossi, Daniela; Collina, Simona | |
| On the study of stereoselectivity in the ligand - Sigma1 receptor interaction. | 1-gen-2015 | Rui, Marta; Marra, Annamaria; Rossi, Daniela; Lurini, E; Pricl, S; Collina, Simona | |
| PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 | 1-gen-2017 | Rui, Marta; Rossi, Daniela; Marra, Annamaria; Dondio, Giulio; Tesei, A.; Cortesi, Michela; Collina, Simona | |
| Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers | 1-gen-2024 | Listro, Roberta; Marra, Annamaria; Cavalloro, Valeria; Rossino, Giacomo; Linciano, Pasquale; Rossi, Daniela; Casali, Emanuele; De Amici, Marco; Mazzeo, Giuseppe; Longhi, Giovanna; Fusè, Marco; Dondio, Giulio; Pellavio, Giorgia; Laforenza, Umberto; Schepmann, Dirk; Wünsch, Bernhard; Collina, Simona | |
| Sigma receptor modulators: a patent review. | 1-gen-2013 | Collina, Simona; Gaggeri, RAFFAELLA FRANCESCA; Marra, Annamaria; Bassi, A; Negrinotti, Sara; Negri, Francesca; Rossi, Daniela | |
| Sigma Receptors: Novel Targets For The Treatment Of Highly Malignant Tumors | 1-gen-2017 | Cortesi, Michela; Pignatta, Sara; Collina, Simona; Rui, Marta; Marra, Annamaria; Tosatto, Luigino; Bartolini, Daniela; Nigrisoli, Evandro; Arienti, Andrea Rocca Alice Zamagni Chiara; Zanoni, Michele; Tesei, Anna |