ORENA, BEATRICE SILVIA
ORENA, BEATRICE SILVIA
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
2018-01-01 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors
2017-01-01 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients
2019-01-01 Mori, G; Orena, Bs; Cultrera, I; Barbieri, G; Albertini, Am; Ranzani, Gn; Carnevali, I; Tibiletti, Mg; Pasca, Mr
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
2017-01-01 Oliveira, Pfm; Guidetti, B; Chamayou, A; André Barrès, C; Madacki, J; Korduláková, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Chiarelli, Laurent; Pasca, MARIA ROSALIA; Lherbet, C; Carayon, C; Massou, S; Baron, M; Baltas, M.
New and old hot drug targets in tuberculosis
2016-01-01 Chiarelli, Laurent; Mori, Giorgia; Esposito, Marta; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA
New antitubercular prodrugs with novel mechanisms of action
2018-02-27 Orena, BEATRICE SILVIA
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053
2020-01-01 Chiarelli, Lr; Salina, Eg; Mori, G; Azhikina, T; Riabova, O; Lepioshkin, A; Grigorov, A; Forbak, M; Madacki, J; Orena, Bs; Manfredi, M; Gosetti, F; Buzzi, A; Degiacomi, G; Sammartino, Jc; Marengo, E; Korduláková, J; Riccardi, G; Mikušová, K; Makarov, V; Pasca, Mr.
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents.
2019-01-01 Meta, E; Brullo, C; Tonelli, M; Franzblau, Sg; Wang, Y; Ma, R; Baojie, W; Orena, Bs; Pasca, Mr; Bruno, O.
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis.
2016-01-01 Matviiuk, T; Madacki, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Menendez, C; Kysil, A; André Barrès, C; Rodriguez, F; Korduláková, J; Mallet Ladeira, S; Voitenko, Z; Pasca, MARIA ROSALIA; Lherbet, C; Baltas, M.
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug
2020-01-01 Mori, G; Silvia Orena, B; Chiarelli, Lr; Degiacomi, G; Riabova, O; Sammartino, Jc; Makarov, V; Riccardi, G; Pasca, M
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
2018-01-01 Mori, G; Orena, Bs; Franch, C; Mitchenall, La; Godbole, Aa; Rodrigues, L; Aguilar-Pérez, C; Zemanová, J; Huszár, S; Forbak, M; Lane, Tr; Sabbah, M; Deboosere, N; Frita, R; Vandeputte, A; Hoffmann, E; Russo, R; Connell, N; Veilleux, C; Kumar, R; Kumar, P; Freundlich, Js; Brodin, P; Aínsa, Ja; Nagaraja, V; Maxwell, A; Mikušová, K; Pasca, Mr; Ekins, S.
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity.
2016-01-01 Veau, D; Krykun, S; Mori, Giorgia; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA; Frongia, C; Lobjois, V; Chassaing, S; Lherbet, C; Baltas, M.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK | 1-gen-2018 | Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr | |
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors | 1-gen-2017 | Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent | |
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients | 1-gen-2019 | Mori, G; Orena, Bs; Cultrera, I; Barbieri, G; Albertini, Am; Ranzani, Gn; Carnevali, I; Tibiletti, Mg; Pasca, Mr | |
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. | 1-gen-2017 | Oliveira, Pfm; Guidetti, B; Chamayou, A; André Barrès, C; Madacki, J; Korduláková, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Chiarelli, Laurent; Pasca, MARIA ROSALIA; Lherbet, C; Carayon, C; Massou, S; Baron, M; Baltas, M. | |
New and old hot drug targets in tuberculosis | 1-gen-2016 | Chiarelli, Laurent; Mori, Giorgia; Esposito, Marta; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA | |
New antitubercular prodrugs with novel mechanisms of action | 27-feb-2018 | Orena, BEATRICE SILVIA | |
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 | 1-gen-2020 | Chiarelli, Lr; Salina, Eg; Mori, G; Azhikina, T; Riabova, O; Lepioshkin, A; Grigorov, A; Forbak, M; Madacki, J; Orena, Bs; Manfredi, M; Gosetti, F; Buzzi, A; Degiacomi, G; Sammartino, Jc; Marengo, E; Korduláková, J; Riccardi, G; Mikušová, K; Makarov, V; Pasca, Mr. | |
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. | 1-gen-2019 | Meta, E; Brullo, C; Tonelli, M; Franzblau, Sg; Wang, Y; Ma, R; Baojie, W; Orena, Bs; Pasca, Mr; Bruno, O. | |
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. | 1-gen-2016 | Matviiuk, T; Madacki, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Menendez, C; Kysil, A; André Barrès, C; Rodriguez, F; Korduláková, J; Mallet Ladeira, S; Voitenko, Z; Pasca, MARIA ROSALIA; Lherbet, C; Baltas, M. | |
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug | 1-gen-2020 | Mori, G; Silvia Orena, B; Chiarelli, Lr; Degiacomi, G; Riabova, O; Sammartino, Jc; Makarov, V; Riccardi, G; Pasca, M | |
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase | 1-gen-2018 | Mori, G; Orena, Bs; Franch, C; Mitchenall, La; Godbole, Aa; Rodrigues, L; Aguilar-Pérez, C; Zemanová, J; Huszár, S; Forbak, M; Lane, Tr; Sabbah, M; Deboosere, N; Frita, R; Vandeputte, A; Hoffmann, E; Russo, R; Connell, N; Veilleux, C; Kumar, R; Kumar, P; Freundlich, Js; Brodin, P; Aínsa, Ja; Nagaraja, V; Maxwell, A; Mikušová, K; Pasca, Mr; Ekins, S. | |
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. | 1-gen-2016 | Veau, D; Krykun, S; Mori, Giorgia; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA; Frongia, C; Lobjois, V; Chassaing, S; Lherbet, C; Baltas, M. |