TOSCA, ELENA MARIA
TOSCA, ELENA MARIA
DIPARTIMENTO DI INGEGNERIA INDUSTRIALE E DELL'INFORMAZIONE
A clinical trial simulator to predict the effect of an adaptive dosing regimen of an investigated compound on platelets, white blood cells and haematocrit in patients with Polycythemia Vera
2022-01-01 Tosca, E. M.; Bartolucci, R.; Castellano, S.; Fiorentini, F.; Manzoni, S.; Di Tollo, S.; Caserini, M.; Rocchetti, M.; Bettica, P.; Magni, P.
A Dynamic Energy Budget (DEB) based modeling framework to describe tumor-in-host growth inhibition and cachexia onset during anticancer treatment in in vivo xenograft studies
2021-01-01 Tosca, E. M.; Rocchetti, M.; Magni, P.
A genetic algorithm for covariate selection
2021-01-01 Bartolucci, R.; Tosca, E. M.; Magni, P.
A PK/PD model for tumor-in-host growth kinetics following administration of an antiangiogenic agent given alone or in combination regimens
2017-01-01 Tosca, ELENA MARIA; Rocchetti, M.; Magni, Paolo
A Population Dynamic Energy Budget-Based Tumor Growth Inhibition Model for Etoposide Effects on Wistar Rats
2019-01-01 Tosca, E.; Pigatto, M. C.; Dallla Costa, T.; Magni, P.
A translational model-based approach to inform the choice of the dose in phase 1 oncology trials: the case study of erdafitinib
2022-01-01 Tosca, E. M.; Terranova, N.; Stuyckens, K.; Dosne, A. G.; Perera, T.; Vialard, J.; King, P.; Verhulst, T.; Perez-Ruixo, J. J.; Magni, P.; Poggesi, I.
A tumor-in-host DEB-based approach for modeling cachexia and bevacizumab resistance
2020-01-01 Tosca, E. M.; Rocchetti, M.; Pesenti, E.; Magni, P.
A tumor-in-host Dynamic Energy Budget (DEB)-based paradigm for preclinical to clinical translation: predictions of tumor-in-host growth dynamics
2021-01-01 Tosca, E. M.; Castellano, S.; Ronchi, D.; Rocchetti, M.; Magni, P.
A Two-Stages Global Sensitivity Analysis by using the delta sensitivity index in presence of correlated inputs: Application on a Tumor Growth Inhibition model based on the Dynamic Energy Budget theory
2023-01-01 De Carlo, A.; Tosca, E. M.; Melillo, N.; Magni, P.
A Two-Stages Global Sensitivity Analysis in presence of correlated inputs: Application on a Tumor-in-host-growth Inhibition model based on the Dynamic Energy Budget theory
2022-01-01 De Carlo, A.; Tosca, E. M.; Melillo, N.; Magni, P.
Application of Artificial Neural Networks to Predict the Intrinsic Solubility of Drug-Like Molecules
2021-01-01 Tosca, E. M.; Bartolucci, R.; Magni, P.
Artificial intelligence and machine learning: just a hype or a new opportunity for pharmacometrics?
2019-01-01 Bartolucci, R.; Grandoni, S.; Melillo, N.; Nicora, G.; Sauta, E.; Tosca, E. M.; Magni, P.
Cancer Cachexia: A Dynamic Energy Budget ({DEB})-Based Model for Tumor-Related Anorexia and Sarcopenia
2020-01-01 Tosca, E. M.; Montanaro, A.; Rocchetti, M.; Magni, P.
Development of a genetic algorithm for covariate analysis in population pharmacokinetic models
2021-01-01 Bartolucci, R.; Masciale, G.; Tosca, E. M.; Magni, P.
Dynamic Energy Budget (DEB) based models of tumor-in-host growth inhibition and cachexia onset
2019-01-01 Tosca, E. M.; Rocchetti, M.; Pesenti, E.; Magni, P.
Dynamic energy budget based models of tumor-in-host growth inhibition and cachexia onset in preclinical settings.
2019-01-30 Tosca, ELENA MARIA
Evaluation of a PK/PD DEB-based model for tumor-in-host growth kinetics under anticancer treatment
2016-01-01 Tosca, ELENA MARIA; Borella, Elisa; Terranova, Nadia; Rocchetti, M.; Magni, Paolo
Evaluation of a tumor growth inhibition (TGI) model integrating dynamic energy budget (DEB) theory
2016-01-01 Tosca, ELENA MARIA; Borella, Elisa; Terranova, Nadia; Rocchetti, M.; Magni, Paolo
Evaluation of software tools for Bayesian estimation on population models:an update based on current software versions
2018-01-01 Bartolucci, R.; Lavezzi, S. M.; Tosca, E. M.; Melillo, N.; Grandoni, S.; Borella, E.; Pasotti, L.; De Nicolao, G.; Magni, P.
Facing the limits of the genetic algorithms for covariate selection
2022-01-01 Ronchi, D.; Tosca, E. M.; Ravasi, I.; Bartolucci, R.; Magni, P.