FRAAIJE, MARCO WILHELMUS
FRAAIJE, MARCO WILHELMUS
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"
A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center
2023-01-01 Rotilio, L.; Boverio, A.; Nguyen, Q. -T.; Mannucci, B.; Fraaije, M. W.; Mattevi, A.
Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties
2021-01-01 Bailleul, G; Nicoll, Cr; Mascotti, Ml; Mattevi, A; Fraaije, Mw
Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism
2017-01-01 Fiorentini, Filippo; Romero, Elvira; Fraaije, MARCO WILHELMUS; Faber, Kurt; Hall, Mã©lanie; Mattevi, Andrea
Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis
2024-01-01 Tjallinks, G.; Mattevi, A.; Fraaije, M. W.
Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)
2019-01-01 Lončar, Nikola; Fiorentini, Filippo; Bailleul, Gautier; Savino, Simone; Romero, Elvira; Mattevi, Andrea; Fraaije, Marco W.
Crystal structures and atomic model of NADPH oxidase
2017-01-01 Magnani, Francesca; Nenci, Simone; MILLANA FANANAS, Elisa; Ceccon, Marta; Romero, Elvira; Fraaije, MARCO WILHELMUS; Mattevi, Andrea
Dehydrogenase versus Oxidase Function: The Interplay between Substrate Binding and Flavin Microenvironment
2025-01-01 Guerriere, Teresa Benedetta; Vancheri, Alessandro; Ricotti, Ilaria; Serapian, Stefano A.; Eggerichs, Daniel; Tischler, Dirk; Colombo, Giorgio; Mascotti, Maria L.; Fraaije, Marco W.; Mattevi, Andrea
Discovery and biochemical characterization of thermostable glycerol oxidases
2024-01-01 Santema, L. L.; Rotilio, L.; Xiang, R.; Tjallinks, G.; Guallar, V.; Mattevi, A.; Fraaije, M. W.
Discovery and structural characterization of a thermostable bacterial monoamine oxidase
2024-01-01 Santema, Lars L.; Basile, Lorenzo; Binda, Claudia; Fraaije, Marco W.
Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis
2021-01-01 Alvigini, L.; Gran-Scheuch, A.; Guo, Y.; Trajkovic, M.; Saifuddin, M.; Fraaije, M. W.; Mattevi, A.
Efficient Oxidation of 5-Hydroxymethylfurfural Using a Flavoprotein Oxidase from the Honeybee Apis mellifera
2023-01-01 Tjallinks, G.; Boverio, A.; Jager, A. W.; Kaya, S. G.; Mattevi, A.; Fraaije, M. W.
Evolution of enzyme functionality in the flavin-containing monooxygenases
2023-01-01 Bailleul, Gautier; Yang, Guang; Nicoll, Callum R; Mattevi, Andrea; Fraaije, Marco W; Mascotti, Maria Laura
Evolution, structure, and drug-metabolizing activity of mammalian prenylcysteine oxidases
2024-01-01 Barone, M.; Pizzorni, L.; Fraaije, M. W.; Mascotti, M. L.; Mattevi, A.
Impact of ancestral sequence reconstruction on mechanistic and structural enzymology
2023-01-01 Nicoll, C. R.; Massari, M.; Fraaije, M. W.; Mascotti, M. L.; Mattevi, A.
Isolation and characterization of a thermostable F420:NADPH oxidoreductase from Thermobifida fusca
2017-01-01 Kumar, Hemant; Nguyen, QUOC THAI; Binda, Claudia; Mattevi, Andrea; Fraaije, MARCO WILHELMUS
Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase
2018-01-01 Pickl, Mathias; Swoboda, Alexander; Romero, Elvira; Winkler, Christoph K.; Binda, Claudia; Mattevi, Andrea; Faber, Kurt; Fraaije, Marco W.
One-Pot Biocatalytic Synthesis of rac-Syringaresinol from a Lignin-Derived Phenol
2023-01-01 Guo, Y.; Alvigini, L.; Saifuddin, M.; Ashley, B.; Trajkovic, M.; Alonso-Cotchico, L.; Mattevi, A.; Fraaije, M. W.
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates
2017-01-01 Fürst, Mj; Savino, Simone; Dudek, Hm; GOMEZ CASTELLANOS, JOSE RUBEN; Gutiérrez de Souza, C; Rovida, Stefano; Fraaije, MARCO WILHELMUS; Mattevi, Andrea
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes
2018-01-01 Romero, Elvira; Gómez Castellanos, J. Rubén; Gadda, Giovanni; Fraaije, Marco W.; Mattevi, Andrea
Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme
2018-01-01 Fürst, Maximilian J. L. J.; Romero, Elvira; Gómez Castellanos, J. Rúben; Fraaije, MARCO WILHELMUS; Mattevi, Andrea
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center | 1-gen-2023 | Rotilio, L.; Boverio, A.; Nguyen, Q. -T.; Mannucci, B.; Fraaije, M. W.; Mattevi, A. | |
| Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties | 1-gen-2021 | Bailleul, G; Nicoll, Cr; Mascotti, Ml; Mattevi, A; Fraaije, Mw | |
| Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism | 1-gen-2017 | Fiorentini, Filippo; Romero, Elvira; Fraaije, MARCO WILHELMUS; Faber, Kurt; Hall, Mã©lanie; Mattevi, Andrea | |
| Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis | 1-gen-2024 | Tjallinks, G.; Mattevi, A.; Fraaije, M. W. | |
| Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO) | 1-gen-2019 | Lončar, Nikola; Fiorentini, Filippo; Bailleul, Gautier; Savino, Simone; Romero, Elvira; Mattevi, Andrea; Fraaije, Marco W. | |
| Crystal structures and atomic model of NADPH oxidase | 1-gen-2017 | Magnani, Francesca; Nenci, Simone; MILLANA FANANAS, Elisa; Ceccon, Marta; Romero, Elvira; Fraaije, MARCO WILHELMUS; Mattevi, Andrea | |
| Dehydrogenase versus Oxidase Function: The Interplay between Substrate Binding and Flavin Microenvironment | 1-gen-2025 | Guerriere, Teresa Benedetta; Vancheri, Alessandro; Ricotti, Ilaria; Serapian, Stefano A.; Eggerichs, Daniel; Tischler, Dirk; Colombo, Giorgio; Mascotti, Maria L.; Fraaije, Marco W.; Mattevi, Andrea | |
| Discovery and biochemical characterization of thermostable glycerol oxidases | 1-gen-2024 | Santema, L. L.; Rotilio, L.; Xiang, R.; Tjallinks, G.; Guallar, V.; Mattevi, A.; Fraaije, M. W. | |
| Discovery and structural characterization of a thermostable bacterial monoamine oxidase | 1-gen-2024 | Santema, Lars L.; Basile, Lorenzo; Binda, Claudia; Fraaije, Marco W. | |
| Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis | 1-gen-2021 | Alvigini, L.; Gran-Scheuch, A.; Guo, Y.; Trajkovic, M.; Saifuddin, M.; Fraaije, M. W.; Mattevi, A. | |
| Efficient Oxidation of 5-Hydroxymethylfurfural Using a Flavoprotein Oxidase from the Honeybee Apis mellifera | 1-gen-2023 | Tjallinks, G.; Boverio, A.; Jager, A. W.; Kaya, S. G.; Mattevi, A.; Fraaije, M. W. | |
| Evolution of enzyme functionality in the flavin-containing monooxygenases | 1-gen-2023 | Bailleul, Gautier; Yang, Guang; Nicoll, Callum R; Mattevi, Andrea; Fraaije, Marco W; Mascotti, Maria Laura | |
| Evolution, structure, and drug-metabolizing activity of mammalian prenylcysteine oxidases | 1-gen-2024 | Barone, M.; Pizzorni, L.; Fraaije, M. W.; Mascotti, M. L.; Mattevi, A. | |
| Impact of ancestral sequence reconstruction on mechanistic and structural enzymology | 1-gen-2023 | Nicoll, C. R.; Massari, M.; Fraaije, M. W.; Mascotti, M. L.; Mattevi, A. | |
| Isolation and characterization of a thermostable F420:NADPH oxidoreductase from Thermobifida fusca | 1-gen-2017 | Kumar, Hemant; Nguyen, QUOC THAI; Binda, Claudia; Mattevi, Andrea; Fraaije, MARCO WILHELMUS | |
| Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase | 1-gen-2018 | Pickl, Mathias; Swoboda, Alexander; Romero, Elvira; Winkler, Christoph K.; Binda, Claudia; Mattevi, Andrea; Faber, Kurt; Fraaije, Marco W. | |
| One-Pot Biocatalytic Synthesis of rac-Syringaresinol from a Lignin-Derived Phenol | 1-gen-2023 | Guo, Y.; Alvigini, L.; Saifuddin, M.; Ashley, B.; Trajkovic, M.; Alonso-Cotchico, L.; Mattevi, A.; Fraaije, M. W. | |
| Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates | 1-gen-2017 | Fürst, Mj; Savino, Simone; Dudek, Hm; GOMEZ CASTELLANOS, JOSE RUBEN; Gutiérrez de Souza, C; Rovida, Stefano; Fraaije, MARCO WILHELMUS; Mattevi, Andrea | |
| Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes | 1-gen-2018 | Romero, Elvira; Gómez Castellanos, J. Rubén; Gadda, Giovanni; Fraaije, Marco W.; Mattevi, Andrea | |
| Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme | 1-gen-2018 | Fürst, Maximilian J. L. J.; Romero, Elvira; Gómez Castellanos, J. Rúben; Fraaije, MARCO WILHELMUS; Mattevi, Andrea |