Congenital infection with human cytomegalovirus (CMV) is a major cause of morbidity and mortality. In an uncontrolled study published in 2005, administration of CMV-specific hyperimmune globulin to pregnant women with primary CMV infection significantly reduced the rate of intrauterine transmission, from 40% to 16%.

A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus

REVELLO, MARIA GRAZIA;SPINILLO, ARSENIO;GUASCHINO, SECONDO;AROSSA, ALESSIA;KLERSY, CATHERINE;GERNA, GIUSEPPE
2014-01-01

Abstract

Congenital infection with human cytomegalovirus (CMV) is a major cause of morbidity and mortality. In an uncontrolled study published in 2005, administration of CMV-specific hyperimmune globulin to pregnant women with primary CMV infection significantly reduced the rate of intrauterine transmission, from 40% to 16%.
2014
Medical Research, Diagnosis & Treatment contains studies of existing and developing diagnostic and therapeutic techniques, as well as specific classes of clinical intervention. Resources in this category emphasize the difference between normal and disease states, with the ultimate goal of more effective diagnosis and intervention. Specific areas of interest include pathology and histochemical analysis of tissue, clinical chemistry and biochemical analysis of medical samples, diagnostic imaging, radiology and radiation, surgical research, anesthesiology and anesthesia, transplantation, artificial tissues, and medical implants. Resources focused on the disease, diagnosis, and treatment of specific organs or physiological systems are excluded and are covered in the Medical Research: Organs & Systems category.
Sì, ma tipo non specificato
Inglese
Internazionale
ELETTRONICO
370
14
1316-26
1326
Adult; Amniocentesis; Cytomegalovirus; Cytomegalovirus Infections; Female; Fetal Diseases; Humans; Immunoglobulins; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious
17
info:eu-repo/semantics/article
262
Revello, MARIA GRAZIA; Lazzarotto, Tiziana; Guerra, Brunella; Spinillo, Arsenio; Ferrazzi, Enrico; Kustermann, Alessandra; Guaschino, Secondo; Vergani...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1101037
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