Purpose: The accurate and fast calculation of the dose in proton radiation therapy is an essential ingredient for successful treatments. We propose a novel approach with a minimal number of parameters. Methods: The approach is based on the exact calculation of the electromagnetic part of the interaction, namely the Moliere theory of the multiple Coulomb scattering for the transversal 1D projection and the Bethe-Bloch formula for the longitudinal stopping power profile, including a gaussian energy straggling. To this e.m. contribution the nuclear proton-nucleus interaction is added with a simple two-parameter model. Then, the non gaussian lateral profile is used to calculate the radial dose distribution with a method that assumes the cylindrical symmetry of the distribution.

An accurate model for the computation of the dose of protons in water

EMBRIACO, ALESSIA;BELLINZONA, VALENTINA ELETTRA;FONTANA, ANDREA;ROTONDI, ALBERTO
2017-01-01

Abstract

Purpose: The accurate and fast calculation of the dose in proton radiation therapy is an essential ingredient for successful treatments. We propose a novel approach with a minimal number of parameters. Methods: The approach is based on the exact calculation of the electromagnetic part of the interaction, namely the Moliere theory of the multiple Coulomb scattering for the transversal 1D projection and the Bethe-Bloch formula for the longitudinal stopping power profile, including a gaussian energy straggling. To this e.m. contribution the nuclear proton-nucleus interaction is added with a simple two-parameter model. Then, the non gaussian lateral profile is used to calculate the radial dose distribution with a method that assumes the cylindrical symmetry of the distribution.
2017
Applied Physics/Condensed Matter/Materials Science encompasses the resources of three related disciplines: Applied Physics, Condensed Matter Physics, and Materials Science. The applied physics resources are concerned with the applications of topics in condensed matter as well as optics, vacuum science, lasers, electronics, cryogenics, magnets and magnetism, acoustical physics and mechanics. The condensed matter physics resources are concerned with the study of the structure and the thermal, mechanical, electrical, magnetic and optical properties of condensed matter. They include superconductivity, surfaces, interfaces, thin films, dielectrics, ferroelectrics and semiconductors. The materials science resources are concerned with the physics and chemistry of materials and include ceramics, composites, alloys, metals and metallurgy, nanotechnology, nuclear materials, adhesion and adhesives. Resources dealing with polymeric materials are listed in the Organic Chemistry/Polymer Science category.
Esperti anonimi
Inglese
Internazionale
STAMPA
38
66
75
10
Field size factor; Proton therapy; Three-dimensional dose distribution; Biophysics; Radiology, Nuclear Medicine and Imaging; Physics and Astronomy (all)
www.fisicamedica.org
no
4
info:eu-repo/semantics/article
262
Embriaco, Alessia; Bellinzona, VALENTINA ELETTRA; Fontana, Andrea; Rotondi, Alberto
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1193777
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