Cytotoxicity evaluation of a new ozonized olive oil

Colombo, Marco
Writing – Original Draft Preparation
;
Ceci, Matteo
Data Curation
;
Poggio, Claudio
Supervision
;
Pietrocola, Giampiero
Writing – Review & Editing
2018-01-01

2018
Medical Research, Organs & Systems includes resources dealing with the normal and disease states of single organs, tissues, or single physiological systems, exclusive of the heart, vascular and immune systems. Systems covered here include hepatology, pulmonary function/physiology, gastroenterology, otolaryngology, respiratory system, andrology, gynecology and reproduction, dermatology, and dentistry/odontology. Resources dealing with general physiology, classes of disease that immediately affect many or all body systems, and medical research focused on specific types of medical intervention are excluded.
Esperti anonimi
Inglese
Internazionale
ELETTRONICO
12
4
585
589
5
OBJECTIVE: The cytocompatibility of a new ozonized olive oil toward immortalized human gingival fibroblasts (HGFs) was evaluated and compared with two common antimicrobial agents based on chlorhexidine digluconate (CHX). MATERIALS AND METHODS: The cytocompatibility of the samples was tested on immortalized HGF-1 cells by 3-(4, 5-dimethyl thiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay. The cells were incubated for 2 or 24 h with increasing dilution of ozonized olive oil or CHX agents. The percentage of viable cells was calculated relative to control cells set to 100%. RESULTS: The ozonized olive oil is cytocompatible, and the viability values of the cells treated for 2 or 24 h with increasing concentrations of ozonized olive oil were significantly higher (P < 0.01) compared with the values obtained using CHX. CONCLUSIONS: The present data demonstrate that due to its cytocompatibility, the new ozonized olive oil could be considered an alternative antibacterial agent.
3-(4; 5-dimethyl thiazolyl-2)-2; 5-diphenyltetrazolium bromide test; cytotoxicity; gingival fibroblast; ozonized olive oil; Dentistry (all)
http://www.eurjdent.com/
no
5
info:eu-repo/semantics/article
262
Colombo, Marco; Ceci, Matteo; Felisa, Eleonora; Poggio, Claudio; Pietrocola, Giampiero
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1254966
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