Implementation of an Advanced Frequency-Based Hebbian Spike Timing Dependent Plasticity

The brain is provided with an enormous computing capability and exploits neural plasticity to store and elaborate complex information. One of the multiple mechanisms that neural circuits express is the Spike-timing-dependent plasticity (STDP), a form of long-term synaptic plasticity exploiting the time relationship between pre- and post-synaptic action potentials (i.e., neuron spikes). It has been found that in certain cases, for instance at the input stage of the cerebellum, between mossy fibers and granular neurons, the plasticity is not only driven by the timing of the spikes, but also by the oscillation frequency of the inputs. This complex behaviour has been implemented in this work, where we developed a novel form of advanced synaptic plasticity model to be used in a well-established neural network simulator (NEST). The subsequent tests proved the proper functioning of the plasticity and its range of applicability, demonstrating the possibility to adopt it in noisy and variable conditions, similar to the biological settings.