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EnglishWe examined a set of populations mainly from Europe but also from the Middle East and North Africa for three Y-linked microsatellites YCAII, DYS19 (about 1300 individuals) and DYS392 (about 350 individuals). Three markers (YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp) show decreasing gradiente of frequency from western Europe toward the Middle East which paralel that of the proto-European 49a,f/TaqI Ht 15. Indeed, a strong linkage disequilibrium between these markers and the 49a,f Ht 15 is observed. We therefore suggest that the 49a,f/TaqI Ht 15, YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp Y chromosome could represent a component of the proto-European gene pool. This European specific compound haplotype distinctively characterizes western Europeans and its very high incidente in these populations (particularly in the Basques) is discussed.
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http://hdl.handle.net/11571/1494| Titolo: | Further characteristics of proto-European Y-chromosomes. |
| Autori interni: | SEMINO, ORNELLA BENERECETTI, AUGUSTA SILVANA |
| Data di pubblicazione: | 1999 |
| Rivista: | EUROPEAN JOURNAL OF HUMAN GENETICS |
| Abstract: | We examined a set of populations mainly from Europe but also from the Middle East and North Africa for three Y-linked microsatellites YCAII, DYS19 (about 1300 individuals) and DYS392 (about 350 individuals). Three markers (YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp) show decreasing gradiente of frequency from western Europe toward the Middle East which paralel that of the proto-European 49a,f/TaqI Ht 15. Indeed, a strong linkage disequilibrium between these markers and the 49a,f Ht 15 is observed. We therefore suggest that the 49a,f/TaqI Ht 15, YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp Y chromosome could represent a component of the proto-European gene pool. This European specific compound haplotype distinctively characterizes western Europeans and its very high incidente in these populations (particularly in the Basques) is discussed. |
| Handle: | http://hdl.handle.net/11571/1494 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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