We examined a set of populations mainly from Europe but also from the Middle East and North Africa for three Y-linked microsatellites YCAII, DYS19 (about 1300 individuals) and DYS392 (about 350 individuals). Three markers (YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp) show decreasing gradiente of frequency from western Europe toward the Middle East which paralel that of the proto-European 49a,f/TaqI Ht 15. Indeed, a strong linkage disequilibrium between these markers and the 49a,f Ht 15 is observed. We therefore suggest that the 49a,f/TaqI Ht 15, YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp Y chromosome could represent a component of the proto-European gene pool. This European specific compound haplotype distinctively characterizes western Europeans and its very high incidente in these populations (particularly in the Basques) is discussed.
Further characteristics of proto-European Y-chromosomes.
SEMINO, ORNELLA;BENERECETTI, AUGUSTA SILVANA
1999-01-01
Abstract
We examined a set of populations mainly from Europe but also from the Middle East and North Africa for three Y-linked microsatellites YCAII, DYS19 (about 1300 individuals) and DYS392 (about 350 individuals). Three markers (YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp) show decreasing gradiente of frequency from western Europe toward the Middle East which paralel that of the proto-European 49a,f/TaqI Ht 15. Indeed, a strong linkage disequilibrium between these markers and the 49a,f Ht 15 is observed. We therefore suggest that the 49a,f/TaqI Ht 15, YCAII a5-b1 Ht, DYS19-190 bp and DYS392-254 bp Y chromosome could represent a component of the proto-European gene pool. This European specific compound haplotype distinctively characterizes western Europeans and its very high incidente in these populations (particularly in the Basques) is discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
