Micellar devices contain a lipophilic complex and a fluorescent ligand for the apical position of the metal complexes. Addition of competing lipophilic molecules results in the displacement of the fluorescent ligand from the metal centre and in a change in fluorescent intensity that is proportional to the lipophilicity of the added molecule
Self-assembled fluorescent micellar devices for measuring the lipophilicity of drugs
DIAZ FERNANDEZ, YURI ANTONIO;PALLAVICINI, PIERSANDRO;PASOTTI, LUCA;
2009-01-01
Abstract
Micellar devices contain a lipophilic complex and a fluorescent ligand for the apical position of the metal complexes. Addition of competing lipophilic molecules results in the displacement of the fluorescent ligand from the metal centre and in a change in fluorescent intensity that is proportional to the lipophilicity of the added moleculeFile in questo prodotto:
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