Investigation of physico-chemical properties of delta-, epsilon- and iota-cyclodextrins by means of thermal analysis (DSC and TG) supported by X-Ray powder diffraction has been done. Studies on dehydration-rehydration behaviour demonstrated that dehydrated delta-cyclodextrin may transform under controlled humidity conditions to a heptahydrate and dehydrated epsilon-cyclodextrin to an amorphous form, while the dehydrated iota-cyclodextrin reverted to the starting nonhydrate crystal form.
Large-ring cyclodextrins: physical chemical characterization and potential use in drug delivery
BETTINETTI, GIAMPIERO;SORRENTI, MILENA LILLINA
1999-01-01
Abstract
Investigation of physico-chemical properties of delta-, epsilon- and iota-cyclodextrins by means of thermal analysis (DSC and TG) supported by X-Ray powder diffraction has been done. Studies on dehydration-rehydration behaviour demonstrated that dehydrated delta-cyclodextrin may transform under controlled humidity conditions to a heptahydrate and dehydrated epsilon-cyclodextrin to an amorphous form, while the dehydrated iota-cyclodextrin reverted to the starting nonhydrate crystal form.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
