In this work the hydrophobic core of Inulin based micelles has been exploited for the loading of the model hydrophobic drug curcumin (solubility ≈ 11ng/ml), the drug release studies have been performed in simulated physiological fluids. Furthermore, biological studies on suitable cell lines have been performed to verify the biocompatibility of INVITE conjugates.
Nanostructured polymeric functional micelles for drug delivery applications
TRIPODO, GIUSEPPE;DORATI, ROSSELLA;GENTA, IDA;CONTI, BICE
2013-01-01
Abstract
In this work the hydrophobic core of Inulin based micelles has been exploited for the loading of the model hydrophobic drug curcumin (solubility ≈ 11ng/ml), the drug release studies have been performed in simulated physiological fluids. Furthermore, biological studies on suitable cell lines have been performed to verify the biocompatibility of INVITE conjugates.File in questo prodotto:
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