The natural composite assembly of wool, made of cortical cells embedded in a highly crosslinked, sulphur-rich keratin matrix, has been exploited to prepare keratin-based biomaterials for tissue engineering. Disruption of the wool fibre structure by ultra-sonication after mild alkali treatment, produced a suspension of cortical cells in aqueous hydrolysed protein solution, that was cast into films and sponges with perspective for tissue engineering, in particular for bone reconstruction.
Keratin based materials with perspective biomedical applications
PATRUCCO, ALESSIA;FASSINA, LORENZO;VISAI, LIVIA;
2014-01-01
Abstract
The natural composite assembly of wool, made of cortical cells embedded in a highly crosslinked, sulphur-rich keratin matrix, has been exploited to prepare keratin-based biomaterials for tissue engineering. Disruption of the wool fibre structure by ultra-sonication after mild alkali treatment, produced a suspension of cortical cells in aqueous hydrolysed protein solution, that was cast into films and sponges with perspective for tissue engineering, in particular for bone reconstruction.File in questo prodotto:
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