IRIS
GIORGETTI, SOFIA
 Distribuzione geografica
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Continente #
NA - Nord America 3.453
AS - Asia 2.536
EU - Europa 2.331
SA - Sud America 307
AF - Africa 29
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.664
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Nazione #
US - Stati Uniti d'America 3.385
CN - Cina 1.441
IE - Irlanda 582
SG - Singapore 526
HK - Hong Kong 311
FI - Finlandia 300
RU - Federazione Russa 278
BR - Brasile 258
IT - Italia 251
UA - Ucraina 231
DE - Germania 229
GB - Regno Unito 139
SE - Svezia 119
VN - Vietnam 105
FR - Francia 60
CA - Canada 42
IN - India 33
BE - Belgio 28
PL - Polonia 26
MX - Messico 19
ES - Italia 17
JP - Giappone 16
BD - Bangladesh 14
ZA - Sudafrica 14
IQ - Iraq 13
NL - Olanda 13
TR - Turchia 12
AR - Argentina 11
EC - Ecuador 11
CZ - Repubblica Ceca 10
PK - Pakistan 10
LT - Lituania 9
CH - Svizzera 8
UZ - Uzbekistan 8
CO - Colombia 7
AT - Austria 6
ID - Indonesia 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
MA - Marocco 5
PY - Paraguay 5
BO - Bolivia 4
KE - Kenya 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
RO - Romania 4
SA - Arabia Saudita 4
AU - Australia 3
AZ - Azerbaigian 3
JO - Giordania 3
KG - Kirghizistan 3
KR - Corea 3
NO - Norvegia 3
TN - Tunisia 3
AL - Albania 2
CL - Cile 2
CR - Costa Rica 2
EG - Egitto 2
IL - Israele 2
JM - Giamaica 2
KZ - Kazakistan 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
NP - Nepal 2
TW - Taiwan 2
VE - Venezuela 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EU - Europa 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
IM - Isola di Man 1
IR - Iran 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
MD - Moldavia 1
MK - Macedonia 1
MY - Malesia 1
NG - Nigeria 1
OM - Oman 1
PH - Filippine 1
TJ - Tagikistan 1
UY - Uruguay 1
Totale 8.664
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Città #
Dublin 582
Chandler 505
Dallas 356
Beijing 321
Hong Kong 310
Jacksonville 302
Ashburn 277
Singapore 265
Nanjing 264
Boardman 154
Nanchang 128
Helsinki 117
Ann Arbor 115
Princeton 102
Lawrence 97
Hebei 91
Shenyang 88
Changsha 86
Wilmington 84
Los Angeles 80
Medford 76
Jiaxing 70
New York 60
Munich 58
Tianjin 58
Moscow 50
Milan 49
Pavia 47
Hangzhou 46
Redondo Beach 45
Buffalo 43
Ho Chi Minh City 41
Shanghai 39
Turku 36
Woodbridge 33
São Paulo 30
The Dalles 28
Brussels 27
Chicago 27
Falls Church 25
Hanoi 20
Orem 19
Verona 19
Brooklyn 18
Denver 18
Montreal 18
Toronto 18
Warsaw 18
London 16
Phoenix 15
Stockholm 15
Tokyo 15
Frankfurt am Main 13
Norwalk 13
Rio de Janeiro 13
Washington 13
Fairfield 12
San Francisco 12
Santa Clara 11
Boston 10
Charlotte 10
Chennai 10
Houston 10
Piscataway 10
Falkenstein 9
Guangzhou 9
Johannesburg 9
Atlanta 8
Auburn Hills 8
Jinan 8
Poplar 8
Ankara 7
Belo Horizonte 7
Carney 7
Mexico City 7
Sassari 7
Seattle 7
Tashkent 7
Baghdad 6
Columbus 6
Ningbo 6
Amsterdam 5
Bexley 5
Curitiba 5
Guayaquil 5
Hefei 5
Kunming 5
Manchester 5
Porto Alegre 5
Qingdao 5
Santa Fe 5
Asunción 4
Auckland 4
Barbianello 4
Birmingham 4
Biên Hòa 4
Campinas 4
Dongguan 4
Florence 4
Formia 4
Totale 5.770
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Nome #
L'ipotesi della cascata amiloide nella malattia di Alzheimer: studi su strategie di neuroprotezione. 184
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 156
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 153
C. elegans expressing human beta2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype. 143
D-strand perturbation and amyloid propensity in beta-2 microglobulin. 135
Hepatitis C virus-associated cryoglobulinaemicglomerulonephritis with delayed appearance of monoclonal cryoglobulinaemia. 132
Liver biopsy discloses a new apolipoprotein AI hereditary amyloidosis in several unrelated Italian families 130
2-DE AND MALDI-TOF-MS FOR A COMPARATIVE ANALYSIS OF PROTEINS EXPRESSED IN DIFFERENT CELLULAR MODELS OF AMYOTROPHIC LATERAL SCLEROSIS 127
Capillary electrophoresis analysis of different variants of the amyloidogenic protein β2 -microglobulin as a simple tool for misfolding and stability studies 122
Class I Major Histocompatibility Complex, the Trojan horse for secretion of amyloidogenic β2-microglobulin. 118
Search of ligands for the amyloidogenic protein beta(2)-microglobulin by capillary electrophoresis and other techniques 114
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 113
Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure. 113
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis 112
Heparin strongly enhances the formation of beta 2-microglobulin amyloid fibrils in the presence of type I collagen 110
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 109
Atomic structure of a nanobody trapped domain swapped dimer of an amyloidogenic β2-microglobulin variant 108
Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS 108
A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis 107
Capillary electrophoresis investigation of a partially unfolded conformation of Beta 2-microglobulin. 106
Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis. 106
beta 2-microglobulin H31Y variant 3D-structure highlights the protein natural propensity towards intermolecular aggregation 105
Sulfonated molecules that bind a partially structured species of beta2-microglobulin also influence refolding and fibrillogenesis. 105
“Separation and quantification of two beta2-microglobulin isoforms”. 104
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation 102
Amyloid persistence in decellularized liver: Biochemical and histopathological characterization 102
Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I. 101
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. 100
Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins 100
Effect of tetracyclines on the dynamics of formation and destructuration of {beta}2-microglobulin amyloid fibrils. 100
Metodo per la separazione e la quantificazione di due conformazioni di beta-2-microglobulina in equilibrio dinamico 98
In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study 95
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 95
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms 94
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis. 92
Plasminogen activation triggers transthyretin amyloidogenesis in vitro 92
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis 91
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 91
C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis 91
Fibrillogenesis of human beta2-microglobulin in three-dimensional silicon microstructures 91
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 90
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. 90
Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin 89
Proteomics of beta2-microglobulin amyloid fibrils. 88
Detection of two partially structured species in the folding process of the amyloidogenic protein beta 2-microglobulin 87
Purification and Characterization of Soluble Cichorium intybus Var. silvestre Lipoxygenase 86
Collagen plays an active role in the aggregation of beta 2-microglobulin under physio-pathological conditions of dialysis-related amyloidosis. 85
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes. 85
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils 85
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 84
Screening of Fibrillogenesis Inhibitors of β2-microglobulin: Integrated Strategies by Mass Spectrometry, Capillary Electrophoresis and in Silico Simulations 84
Enhanced molecular chaperone activity of the small heat-shock protein αB-crystallin following covalent immobilization onto a solid-phase support. 83
DETECTION OF FRAGMENTS OF BETA2-MICROGLOBULIN IN AMYLOID FIBRILS 82
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis 81
Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 81
Topological investigation of amyloid fibrils obtained from beta2-microglobulin 79
Structural and folding dynamics properties of T70N variant of human lysozyme. 79
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties. 78
{beta}2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity. 78
An Analysis of Ultrasound Stimulation Effects on C. Elegans Organisms Motility 77
Dynamic of beta(2)-microglobulin fibril formation and reabsorption: the role of proteolysis. 77
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue 77
Exploring exchange processes in proteins by paramagnetic perturbation of NMR spectra 77
Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease". REVIEW ARTICLE 76
Solution structure of beta(2)-microglobulin and insights into fibrillogenesis 76
Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation. 73
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence 73
Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR. 71
Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide. 70
Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin. 70
Screening of fibrillogenesis inhibitors of beta2-microglobulin: integrated strategie by MS, CE and docking Studies 69
Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity 69
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies 69
Lipossigenasi del Cichorium intybus Var. silvestre: isolamento e caratterizzazione 68
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 67
Folding and fibrillogenesis: clues from beta2-microglobulin. 66
Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans 64
The solution structure of human ß2-microglobulin reveals the prodromes of its amyloid transition 64
Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy 64
Properties of some variants of human beta 2- microglobulin and amyloidogenesis. 63
Equilibrium unfolding thermodynamics of {beta}2-microglobulin analyzed through native-state H/D exchange. 62
The effects of an ideal {beta}-turn on {beta}-2 microglobulin fold stability. 62
A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrils 61
Degradation versus fibrillogenesis, two alternative pathways modulated by seeds and glycosaminoglycans 59
S-Homocysteinylation effects on transthyretin: Worsening of cardiomyopathy onset 58
Calcium Binds to Transthyretin with Low Affinity 57
Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation. 56
Effects of a vitamin E-modified dialyzer (Excebrane) on beta-2-microglobulin structure and removal. 56
Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers. 56
Structure, function and amyloidogenic propensity of apolipoprotein A-I. 55
Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein A-I. 54
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states 53
The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease 53
Targeting amyloid aggregation: An overview of strategies and mechanisms 53
Design and Mechanistic Analysis of a Potent Bivalent Inhibitor of Transthyretin Amyloid Fibrillogenesis 48
Truncation of the constant domain drives amyloid formation by immunoglobulin light chains 48
Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity 47
The workings of the amyloid diseases. 44
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 43
Proteomics in protein misfolding diseases. 41
Totale 8.595
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Categoria #
all - tutte 37.985
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.985
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021292 0 0 0 0 0 58 8 67 23 69 55 12
2021/2022441 9 4 7 10 17 30 10 30 26 18 69 211
2022/20231.536 179 128 12 105 166 139 0 77 669 12 35 14
2023/2024540 87 108 28 31 50 128 16 19 5 23 30 15
2024/20251.653 49 120 52 49 53 78 69 116 427 46 189 405
2025/20262.192 293 318 463 500 485 133 0 0 0 0 0 0
Totale 8.828