IRIS
GIORGETTI, SOFIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.572
AS - Asia 3.038
EU - Europa 2.587
SA - Sud America 407
Continente sconosciuto - Info sul continente non disponibili 166
AF - Africa 98
OC - Oceania 9
Totale 10.877
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Nazione #
US - Stati Uniti d'America 4.471
CN - Cina 1.517
SG - Singapore 661
IE - Irlanda 584
HK - Hong Kong 344
IT - Italia 335
BR - Brasile 313
FI - Finlandia 302
RU - Federazione Russa 285
DE - Germania 240
UA - Ucraina 236
VN - Vietnam 222
FR - Francia 163
GB - Regno Unito 153
SE - Svezia 120
IN - India 70
ZA - Sudafrica 63
CA - Canada 52
BD - Bangladesh 34
PL - Polonia 31
BE - Belgio 28
IQ - Iraq 28
MX - Messico 28
AR - Argentina 24
ES - Italia 23
JP - Giappone 21
TR - Turchia 21
NL - Olanda 20
PK - Pakistan 18
CO - Colombia 17
EC - Ecuador 15
ID - Indonesia 13
PH - Filippine 12
CZ - Repubblica Ceca 10
KE - Kenya 9
LT - Lituania 9
UZ - Uzbekistan 9
CH - Svizzera 8
CL - Cile 8
JO - Giordania 8
VE - Venezuela 8
AE - Emirati Arabi Uniti 7
MA - Marocco 7
SA - Arabia Saudita 7
AT - Austria 6
BO - Bolivia 6
CR - Costa Rica 6
PE - Perù 6
AU - Australia 5
JM - Giamaica 5
PY - Paraguay 5
TN - Tunisia 5
AL - Albania 4
AZ - Azerbaigian 4
HN - Honduras 4
HR - Croazia 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
RO - Romania 4
EG - Egitto 3
IL - Israele 3
KG - Kirghizistan 3
KR - Corea 3
KW - Kuwait 3
KZ - Kazakistan 3
MY - Malesia 3
NO - Norvegia 3
TH - Thailandia 3
BG - Bulgaria 2
BH - Bahrain 2
DK - Danimarca 2
ET - Etiopia 2
GP - Guadalupe 2
GR - Grecia 2
HU - Ungheria 2
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LV - Lettonia 2
NP - Nepal 2
PS - Palestinian Territory 2
SN - Senegal 2
TW - Taiwan 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
GE - Georgia 1
GF - Guiana Francese 1
GH - Ghana 1
GN - Guinea 1
GQ - Guinea Equatoriale 1
GY - Guiana 1
IM - Isola di Man 1
IR - Iran 1
Totale 10.700
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Città #
Dublin 584
Chandler 505
San Jose 483
Ashburn 397
Dallas 360
Singapore 345
Hong Kong 338
Beijing 335
Jacksonville 303
Nanjing 264
Boardman 162
Council Bluffs 142
Nanchang 128
Helsinki 119
Ann Arbor 115
Princeton 102
Lawrence 97
Hebei 91
Lauterbourg 91
Shenyang 88
Los Angeles 87
Changsha 86
Wilmington 84
Medford 76
Ho Chi Minh City 70
Jiaxing 70
New York 68
Milan 61
Munich 58
Tianjin 58
Hanoi 57
Johannesburg 50
Moscow 50
Pavia 47
Hangzhou 46
Redondo Beach 45
Buffalo 44
Shanghai 42
São Paulo 39
Santa Clara 37
Turku 36
Orem 35
Woodbridge 33
Chicago 31
The Dalles 29
Brussels 27
Falls Church 25
Brooklyn 23
Frankfurt am Main 22
Montreal 21
Toronto 21
Warsaw 21
Denver 20
Tokyo 20
London 19
Verona 19
Phoenix 18
Chennai 16
Stockholm 16
Washington 16
Houston 15
Atlanta 14
Rio de Janeiro 14
San Francisco 14
Baghdad 13
Norwalk 13
Columbus 12
Fairfield 12
Charlotte 11
Manchester 11
Mexico City 11
Piscataway 11
Amsterdam 10
Boston 10
Belo Horizonte 9
Falkenstein 9
Guangzhou 9
Amman 8
Auburn Hills 8
Biên Hòa 8
Catania 8
Jinan 8
Mumbai 8
Poplar 8
Rome 8
Tashkent 8
Ankara 7
Carney 7
Da Nang 7
Florence 7
Haiphong 7
Hải Dương 7
Nairobi 7
Porto Alegre 7
Sassari 7
Seattle 7
Curitiba 6
Ha Long 6
Naples 6
Ningbo 6
Totale 7.056
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Nome #
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis 208
L'ipotesi della cascata amiloide nella malattia di Alzheimer: studi su strategie di neuroprotezione. 203
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 189
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 182
C. elegans expressing human beta2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype. 173
D-strand perturbation and amyloid propensity in beta-2 microglobulin. 159
2-DE AND MALDI-TOF-MS FOR A COMPARATIVE ANALYSIS OF PROTEINS EXPRESSED IN DIFFERENT CELLULAR MODELS OF AMYOTROPHIC LATERAL SCLEROSIS 157
Liver biopsy discloses a new apolipoprotein AI hereditary amyloidosis in several unrelated Italian families 154
Hepatitis C virus-associated cryoglobulinaemicglomerulonephritis with delayed appearance of monoclonal cryoglobulinaemia. 151
Class I Major Histocompatibility Complex, the Trojan horse for secretion of amyloidogenic β2-microglobulin. 143
Capillary electrophoresis analysis of different variants of the amyloidogenic protein β2 -microglobulin as a simple tool for misfolding and stability studies 139
Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure. 139
Search of ligands for the amyloidogenic protein beta(2)-microglobulin by capillary electrophoresis and other techniques 134
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis 133
Heparin strongly enhances the formation of beta 2-microglobulin amyloid fibrils in the presence of type I collagen 133
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 131
Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS 130
Sulfonated molecules that bind a partially structured species of beta2-microglobulin also influence refolding and fibrillogenesis. 130
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 129
A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis 128
“Separation and quantification of two beta2-microglobulin isoforms”. 124
beta 2-microglobulin H31Y variant 3D-structure highlights the protein natural propensity towards intermolecular aggregation 124
Capillary electrophoresis investigation of a partially unfolded conformation of Beta 2-microglobulin. 124
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation 122
Atomic structure of a nanobody trapped domain swapped dimer of an amyloidogenic β2-microglobulin variant 122
Effect of tetracyclines on the dynamics of formation and destructuration of {beta}2-microglobulin amyloid fibrils. 121
Plasminogen activation triggers transthyretin amyloidogenesis in vitro 121
C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis 121
Metodo per la separazione e la quantificazione di due conformazioni di beta-2-microglobulina in equilibrio dinamico 120
Amyloid persistence in decellularized liver: Biochemical and histopathological characterization 120
Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis. 119
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 118
Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I. 118
Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins 117
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 117
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. 115
Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin 115
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms 114
In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study 113
Fibrillogenesis of human beta2-microglobulin in three-dimensional silicon microstructures 110
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis. 107
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. 106
DETECTION OF FRAGMENTS OF BETA2-MICROGLOBULIN IN AMYLOID FIBRILS 105
Collagen plays an active role in the aggregation of beta 2-microglobulin under physio-pathological conditions of dialysis-related amyloidosis. 103
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 103
Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 103
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils 103
Proteomics of beta2-microglobulin amyloid fibrils. 102
Detection of two partially structured species in the folding process of the amyloidogenic protein beta 2-microglobulin 102
Purification and Characterization of Soluble Cichorium intybus Var. silvestre Lipoxygenase 101
{beta}2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity. 99
Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity 98
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis 98
An Analysis of Ultrasound Stimulation Effects on C. Elegans Organisms Motility 97
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 97
Screening of Fibrillogenesis Inhibitors of β2-microglobulin: Integrated Strategies by Mass Spectrometry, Capillary Electrophoresis and in Silico Simulations 97
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes. 96
Structural and folding dynamics properties of T70N variant of human lysozyme. 96
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties. 95
Solution structure of beta(2)-microglobulin and insights into fibrillogenesis 95
Enhanced molecular chaperone activity of the small heat-shock protein αB-crystallin following covalent immobilization onto a solid-phase support. 95
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue 95
Exploring exchange processes in proteins by paramagnetic perturbation of NMR spectra 94
Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans 92
Topological investigation of amyloid fibrils obtained from beta2-microglobulin 92
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence 92
Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease". REVIEW ARTICLE 91
Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation. 87
Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin. 87
A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrils 87
Dynamic of beta(2)-microglobulin fibril formation and reabsorption: the role of proteolysis. 85
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 85
Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR. 85
Degradation versus fibrillogenesis, two alternative pathways modulated by seeds and glycosaminoglycans 84
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies 82
Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy 82
Truncation of the constant domain drives amyloid formation by immunoglobulin light chains 81
Lipossigenasi del Cichorium intybus Var. silvestre: isolamento e caratterizzazione 80
Properties of some variants of human beta 2- microglobulin and amyloidogenesis. 80
Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide. 79
Screening of fibrillogenesis inhibitors of beta2-microglobulin: integrated strategie by MS, CE and docking Studies 79
Folding and fibrillogenesis: clues from beta2-microglobulin. 79
The solution structure of human ß2-microglobulin reveals the prodromes of its amyloid transition 77
S-Homocysteinylation effects on transthyretin: Worsening of cardiomyopathy onset 76
The effects of an ideal {beta}-turn on {beta}-2 microglobulin fold stability. 74
Design and Mechanistic Analysis of a Potent Bivalent Inhibitor of Transthyretin Amyloid Fibrillogenesis 73
Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation. 73
Equilibrium unfolding thermodynamics of {beta}2-microglobulin analyzed through native-state H/D exchange. 73
Calcium Binds to Transthyretin with Low Affinity 72
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states 72
Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity 70
Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers. 70
Effects of a vitamin E-modified dialyzer (Excebrane) on beta-2-microglobulin structure and removal. 69
The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease 67
Targeting amyloid aggregation: An overview of strategies and mechanisms 66
Structure, function and amyloidogenic propensity of apolipoprotein A-I. 65
Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein A-I. 63
The workings of the amyloid diseases. 61
Fibrillar vs crystalline full-length beta-2-microglobulin studied by high-resolution solid-state NMR spectroscopy. 56
Topologically non-trivial metal-organic assemblies inhibit β2-microglobulin amyloidogenesis 55
Totale 10.548
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Categoria #
all - tutte 46.534
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.534
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022428 0 0 7 10 17 30 10 30 26 18 69 211
2022/20231.536 179 128 12 105 166 139 0 77 669 12 35 14
2023/2024540 87 108 28 31 50 128 16 19 5 23 30 15
2024/20251.653 49 120 52 49 53 78 69 116 427 46 189 405
2025/20263.842 293 318 463 500 485 167 676 144 321 253 76 146
2026/2027399 169 184 46 0 0 0 0 0 0 0 0 0
Totale 10.877