IRIS
GIORGETTI, SOFIA
 Distribuzione geografica
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Continente #
NA - Nord America 2.090
EU - Europa 1.658
AS - Asia 1.056
OC - Oceania 3
SA - Sud America 2
AF - Africa 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.811
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Nazione #
US - Stati Uniti d'America 2.079
CN - Cina 1.043
IE - Irlanda 580
FI - Finlandia 247
UA - Ucraina 228
IT - Italia 183
DE - Germania 144
SE - Svezia 104
GB - Regno Unito 84
FR - Francia 34
BE - Belgio 27
CA - Canada 10
RU - Federazione Russa 8
IN - India 6
PL - Polonia 4
NL - Olanda 3
RO - Romania 3
AU - Australia 2
CH - Svizzera 2
CZ - Repubblica Ceca 2
NO - Norvegia 2
SG - Singapore 2
AT - Austria 1
BR - Brasile 1
CL - Cile 1
EU - Europa 1
HK - Hong Kong 1
IR - Iran 1
JP - Giappone 1
KE - Kenya 1
LV - Lettonia 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
TR - Turchia 1
Totale 4.811
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Città #
Dublin 580
Chandler 505
Jacksonville 302
Nanjing 262
Beijing 147
Ashburn 139
Nanchang 128
Ann Arbor 115
Princeton 102
Helsinki 100
Lawrence 97
Hebei 91
Shenyang 87
Wilmington 84
Changsha 81
Medford 76
Jiaxing 70
Tianjin 50
Boardman 49
Hangzhou 44
Pavia 38
Milan 35
Shanghai 33
Woodbridge 33
Brussels 27
New York 27
Falls Church 25
Verona 19
Norwalk 13
Washington 12
Fairfield 11
Piscataway 10
Toronto 10
Auburn Hills 8
Jinan 7
Los Angeles 7
Ningbo 6
Kunming 5
Formia 4
London 4
Padova 4
Saint Albans 4
San Giuliano Milanese 4
Seattle 4
Berlin 3
Catania 3
Fuzhou 3
Genova 3
Guangzhou 3
Houston 3
Orange 3
Redwood City 3
Silea 3
Birmingham 2
Borås 2
Brescia 2
Düdingen 2
Feldthurns 2
Groningen 2
Hanover 2
Hefei 2
Kamien 2
Lanzhou 2
Lucino 2
Marsciano 2
Nagold 2
Narbonne 2
Oslo 2
Polska 2
Pune 2
Rho 2
San Francisco 2
St Petersburg 2
Taizhou 2
Tappahannock 2
West Jordan 2
Zhengzhou 2
Auckland 1
Augusta 1
Campo Largo 1
Campobasso 1
Central 1
Changchun 1
Charlotte 1
Como 1
Dearborn 1
Des Moines 1
Focsani 1
Genoa 1
Gragnano 1
Guadalupe 1
Huntington 1
Jinhua 1
Kish 1
Kota Kinabalu 1
Las Vegas 1
Leawood 1
Magdeburg 1
Melbourne 1
Montalcino 1
Totale 3.557
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Nome #
L'ipotesi della cascata amiloide nella malattia di Alzheimer: studi su strategie di neuroprotezione. 140
Hepatitis C virus-associated cryoglobulinaemicglomerulonephritis with delayed appearance of monoclonal cryoglobulinaemia. 95
C. elegans expressing human beta2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype. 90
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 85
D-strand perturbation and amyloid propensity in beta-2 microglobulin. 84
Search of ligands for the amyloidogenic protein beta(2)-microglobulin by capillary electrophoresis and other techniques 82
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 75
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. 75
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 74
Sulfonated molecules that bind a partially structured species of beta2-microglobulin also influence refolding and fibrillogenesis. 72
Liver biopsy discloses a new apolipoprotein AI hereditary amyloidosis in several unrelated Italian families 71
Heparin strongly enhances the formation of beta 2-microglobulin amyloid fibrils in the presence of type I collagen 70
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation 68
“Separation and quantification of two beta2-microglobulin isoforms”. 67
Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure. 67
Capillary electrophoresis analysis of different variants of the amyloidogenic protein β2 -microglobulin as a simple tool for misfolding and stability studies 66
Metodo per la separazione e la quantificazione di due conformazioni di beta-2-microglobulina in equilibrio dinamico 65
Collagen plays an active role in the aggregation of beta 2-microglobulin under physio-pathological conditions of dialysis-related amyloidosis. 64
beta 2-microglobulin H31Y variant 3D-structure highlights the protein natural propensity towards intermolecular aggregation 64
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 64
Class I Major Histocompatibility Complex, the Trojan horse for secretion of amyloidogenic β2-microglobulin. 64
Capillary electrophoresis investigation of a partially unfolded conformation of Beta 2-microglobulin. 63
2-DE AND MALDI-TOF-MS FOR A COMPARATIVE ANALYSIS OF PROTEINS EXPRESSED IN DIFFERENT CELLULAR MODELS OF AMYOTROPHIC LATERAL SCLEROSIS 61
Purification and Characterization of Soluble Cichorium intybus Var. silvestre Lipoxygenase 61
Atomic structure of a nanobody trapped domain swapped dimer of an amyloidogenic β2-microglobulin variant 61
Topological investigation of amyloid fibrils obtained from beta2-microglobulin 60
Proteomics of beta2-microglobulin amyloid fibrils. 60
Detection of two partially structured species in the folding process of the amyloidogenic protein beta 2-microglobulin 60
{beta}2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity. 60
Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin 59
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis. 58
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties. 57
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis 57
Solution structure of beta(2)-microglobulin and insights into fibrillogenesis 56
Fibrillogenesis of human beta2-microglobulin in three-dimensional silicon microstructures 56
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 55
Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins 55
Effect of tetracyclines on the dynamics of formation and destructuration of {beta}2-microglobulin amyloid fibrils. 55
A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis 55
Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS 55
Enhanced molecular chaperone activity of the small heat-shock protein αB-crystallin following covalent immobilization onto a solid-phase support. 53
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis 53
Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I. 52
Dynamic of beta(2)-microglobulin fibril formation and reabsorption: the role of proteolysis. 51
Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease". REVIEW ARTICLE 51
In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study 51
Plasminogen activation triggers transthyretin amyloidogenesis in vitro 51
Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis. 50
Screening of Fibrillogenesis Inhibitors of β2-microglobulin: Integrated Strategies by Mass Spectrometry, Capillary Electrophoresis and in Silico Simulations 50
Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide. 49
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 49
Structural and folding dynamics properties of T70N variant of human lysozyme. 49
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 49
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. 48
Lipossigenasi del Cichorium intybus Var. silvestre: isolamento e caratterizzazione 47
Equilibrium unfolding thermodynamics of {beta}2-microglobulin analyzed through native-state H/D exchange. 47
Amyloid persistence in decellularized liver: Biochemical and histopathological characterization 46
Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR. 46
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis 45
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 45
C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis 45
Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity 44
Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation. 43
DETECTION OF FRAGMENTS OF BETA2-MICROGLOBULIN IN AMYLOID FIBRILS 43
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 42
Screening of fibrillogenesis inhibitors of beta2-microglobulin: integrated strategie by MS, CE and docking Studies 41
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue 41
Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 41
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes. 40
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states 39
The effects of an ideal {beta}-turn on {beta}-2 microglobulin fold stability. 39
Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein A-I. 39
The solution structure of human ß2-microglobulin reveals the prodromes of its amyloid transition 39
Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin. 38
Properties of some variants of human beta 2- microglobulin and amyloidogenesis. 36
Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers. 36
Folding and fibrillogenesis: clues from beta2-microglobulin. 35
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies 35
Structure, function and amyloidogenic propensity of apolipoprotein A-I. 35
The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease 34
Targeting amyloid aggregation: An overview of strategies and mechanisms 34
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils 33
Effects of a vitamin E-modified dialyzer (Excebrane) on beta-2-microglobulin structure and removal. 32
Exploring exchange processes in proteins by paramagnetic perturbation of NMR spectra 32
Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation. 28
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 28
S-Homocysteinylation effects on transthyretin: Worsening of cardiomyopathy onset 28
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms 28
Proteomics in protein misfolding diseases. 27
The interaction of β2-microglobulin with gold nanoparticles: Impact of coating, charge and size 24
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence 24
Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association 23
The workings of the amyloid diseases. 23
Fibrillar vs crystalline full-length beta-2-microglobulin studied by high-resolution solid-state NMR spectroscopy. 21
Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy 19
An Analysis of Ultrasound Stimulation Effects on C. Elegans Organisms Motility 18
Decoding the structural bases of D76N β2-microglobulin high amyloidogenicity through crystallography and asn-scan mutagenesis 17
The corona of protein-gold nanoparticle systems: The role of ionic strength 17
Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans 9
Calcium Binds to Transthyretin with Low Affinity 8
Totale 4.946
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Categoria #
all - tutte 17.539
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.539
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201911 0 0 0 0 0 0 0 0 0 0 3 8
2019/20201.227 359 483 2 47 9 44 11 46 5 125 76 20
2020/2021482 75 42 15 49 9 58 8 67 23 69 55 12
2021/2022441 9 4 7 10 17 30 10 30 26 18 69 211
2022/20231.536 179 128 12 105 166 139 0 77 669 12 35 14
2023/2024513 87 108 28 31 50 128 16 19 5 23 18 0
Totale 4.956