IRIS
GIORGETTI, SOFIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.004
AS - Asia 3.001
EU - Europa 2.517
SA - Sud America 402
AF - Africa 98
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 1
Totale 10.032
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Nazione #
US - Stati Uniti d'America 3.923
CN - Cina 1.504
SG - Singapore 649
IE - Irlanda 584
HK - Hong Kong 341
BR - Brasile 310
FI - Finlandia 302
RU - Federazione Russa 285
IT - Italia 276
DE - Germania 240
UA - Ucraina 236
VN - Vietnam 222
FR - Francia 160
GB - Regno Unito 153
SE - Svezia 120
IN - India 69
ZA - Sudafrica 63
CA - Canada 47
BD - Bangladesh 30
PL - Polonia 30
BE - Belgio 28
IQ - Iraq 27
AR - Argentina 24
MX - Messico 24
JP - Giappone 21
TR - Turchia 21
ES - Italia 20
NL - Olanda 18
PK - Pakistan 18
CO - Colombia 15
EC - Ecuador 15
ID - Indonesia 12
PH - Filippine 11
CZ - Repubblica Ceca 10
KE - Kenya 9
LT - Lituania 9
UZ - Uzbekistan 9
CH - Svizzera 8
CL - Cile 8
JO - Giordania 8
VE - Venezuela 8
AE - Emirati Arabi Uniti 7
MA - Marocco 7
SA - Arabia Saudita 7
AT - Austria 6
BO - Bolivia 6
PE - Perù 6
AU - Australia 5
PY - Paraguay 5
TN - Tunisia 5
AL - Albania 4
AZ - Azerbaigian 4
HR - Croazia 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
RO - Romania 4
EG - Egitto 3
IL - Israele 3
KG - Kirghizistan 3
KR - Corea 3
KW - Kuwait 3
KZ - Kazakistan 3
MY - Malesia 3
NO - Norvegia 3
BG - Bulgaria 2
BH - Bahrain 2
CR - Costa Rica 2
DK - Danimarca 2
ET - Etiopia 2
HN - Honduras 2
JM - Giamaica 2
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LV - Lettonia 2
NP - Nepal 2
PS - Palestinian Territory 2
SN - Senegal 2
TH - Thailandia 2
TW - Taiwan 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
GE - Georgia 1
GF - Guiana Francese 1
GH - Ghana 1
GN - Guinea 1
GP - Guadalupe 1
GQ - Guinea Equatoriale 1
GR - Grecia 1
GY - Guiana 1
HU - Ungheria 1
IM - Isola di Man 1
IR - Iran 1
Totale 10.021
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Città #
Dublin 584
Chandler 505
Ashburn 357
Dallas 356
San Jose 354
Singapore 339
Hong Kong 336
Beijing 331
Jacksonville 302
Nanjing 264
Boardman 154
Nanchang 128
Helsinki 119
Ann Arbor 115
Princeton 102
Lawrence 97
Hebei 91
Lauterbourg 91
Shenyang 88
Changsha 86
Los Angeles 84
Wilmington 84
Medford 76
Ho Chi Minh City 70
Jiaxing 70
New York 64
Munich 58
Tianjin 58
Hanoi 57
Milan 51
Johannesburg 50
Moscow 50
Pavia 47
Hangzhou 46
Redondo Beach 45
Buffalo 44
Shanghai 41
São Paulo 37
Turku 36
Orem 35
Woodbridge 33
Chicago 29
The Dalles 28
Brussels 27
Falls Church 25
Frankfurt am Main 22
Toronto 21
Warsaw 21
Montreal 20
Tokyo 20
Brooklyn 19
Denver 19
London 19
Santa Clara 19
Verona 19
Chennai 16
Stockholm 16
Phoenix 15
Rio de Janeiro 14
Baghdad 13
Norwalk 13
Washington 13
Fairfield 12
San Francisco 12
Charlotte 11
Piscataway 11
Amsterdam 10
Boston 10
Houston 10
Manchester 10
Atlanta 9
Belo Horizonte 9
Falkenstein 9
Guangzhou 9
Amman 8
Auburn Hills 8
Biên Hòa 8
Catania 8
Council Bluffs 8
Jinan 8
Mexico City 8
Mumbai 8
Poplar 8
Tashkent 8
Ankara 7
Carney 7
Da Nang 7
Haiphong 7
Hải Dương 7
Nairobi 7
Porto Alegre 7
Sassari 7
Seattle 7
Columbus 6
Curitiba 6
Ha Long 6
Ningbo 6
Bexley 5
Cape Town 5
Guayaquil 5
Totale 6.647
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Nome #
L'ipotesi della cascata amiloide nella malattia di Alzheimer: studi su strategie di neuroprotezione. 198
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 177
A quantitative and qualitative method for direct 2-DE analysis of murine cartilage 175
C. elegans expressing human beta2-microglobulin: a novel model for studying the relationship between the molecular assembly and the toxic phenotype. 169
D-strand perturbation and amyloid propensity in beta-2 microglobulin. 153
Hepatitis C virus-associated cryoglobulinaemicglomerulonephritis with delayed appearance of monoclonal cryoglobulinaemia. 147
2-DE AND MALDI-TOF-MS FOR A COMPARATIVE ANALYSIS OF PROTEINS EXPRESSED IN DIFFERENT CELLULAR MODELS OF AMYOTROPHIC LATERAL SCLEROSIS 147
Liver biopsy discloses a new apolipoprotein AI hereditary amyloidosis in several unrelated Italian families 146
Class I Major Histocompatibility Complex, the Trojan horse for secretion of amyloidogenic β2-microglobulin. 139
Capillary electrophoresis analysis of different variants of the amyloidogenic protein β2 -microglobulin as a simple tool for misfolding and stability studies 136
Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure. 136
Beta2-microglobulin isoforms display an heterogeneous affinity for type I collagen. 129
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis 127
Heparin strongly enhances the formation of beta 2-microglobulin amyloid fibrils in the presence of type I collagen 127
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 126
Sulfonated molecules that bind a partially structured species of beta2-microglobulin also influence refolding and fibrillogenesis. 126
Search of ligands for the amyloidogenic protein beta(2)-microglobulin by capillary electrophoresis and other techniques 125
A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis 123
Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS 123
beta 2-microglobulin H31Y variant 3D-structure highlights the protein natural propensity towards intermolecular aggregation 120
Capillary electrophoresis investigation of a partially unfolded conformation of Beta 2-microglobulin. 119
“Separation and quantification of two beta2-microglobulin isoforms”. 118
Atomic structure of a nanobody trapped domain swapped dimer of an amyloidogenic β2-microglobulin variant 118
Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis. 118
C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis 116
DE loop mutations affect beta2-microglobulin stability and amyloid aggregation 115
Amyloid persistence in decellularized liver: Biochemical and histopathological characterization 115
Effect of tetracyclines on the dynamics of formation and destructuration of {beta}2-microglobulin amyloid fibrils. 115
Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I. 115
Metodo per la separazione e la quantificazione di due conformazioni di beta-2-microglobulina in equilibrio dinamico 114
Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins 113
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis 113
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 112
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms 111
Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin 110
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. 109
Plasminogen activation triggers transthyretin amyloidogenesis in vitro 108
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 108
In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study 105
Fibrillogenesis of human beta2-microglobulin in three-dimensional silicon microstructures 104
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis. 103
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. 101
Proteomics of beta2-microglobulin amyloid fibrils. 99
Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins 99
DETECTION OF FRAGMENTS OF BETA2-MICROGLOBULIN IN AMYLOID FIBRILS 99
Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 98
Purification and Characterization of Soluble Cichorium intybus Var. silvestre Lipoxygenase 97
Detection of two partially structured species in the folding process of the amyloidogenic protein beta 2-microglobulin 97
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils 97
Structural features of two monoclonal cryocrystalglobulins causing a rheumatic syndrome with vasculitis 94
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis 94
An Analysis of Ultrasound Stimulation Effects on C. Elegans Organisms Motility 93
Collagen plays an active role in the aggregation of beta 2-microglobulin under physio-pathological conditions of dialysis-related amyloidosis. 93
{beta}2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity. 93
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes. 93
Solution structure of beta(2)-microglobulin and insights into fibrillogenesis 91
Exploring exchange processes in proteins by paramagnetic perturbation of NMR spectra 91
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties. 90
Enhanced molecular chaperone activity of the small heat-shock protein αB-crystallin following covalent immobilization onto a solid-phase support. 90
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue 90
Structural and folding dynamics properties of T70N variant of human lysozyme. 90
Topological investigation of amyloid fibrils obtained from beta2-microglobulin 89
Screening of Fibrillogenesis Inhibitors of β2-microglobulin: Integrated Strategies by Mass Spectrometry, Capillary Electrophoresis and in Silico Simulations 89
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence 89
Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease". REVIEW ARTICLE 86
Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity 85
Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation. 82
Structure, folding dynamics and amyloidogenesis of Asp76Asn β2-microglobulin: roles of shear flow, hydrophobic surfaces and α crystallin. 82
Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans 81
Dynamic of beta(2)-microglobulin fibril formation and reabsorption: the role of proteolysis. 81
A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrils 81
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies 80
Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential 79
Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR. 78
Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy 78
Degradation versus fibrillogenesis, two alternative pathways modulated by seeds and glycosaminoglycans 77
Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide. 76
Screening of fibrillogenesis inhibitors of beta2-microglobulin: integrated strategie by MS, CE and docking Studies 75
Lipossigenasi del Cichorium intybus Var. silvestre: isolamento e caratterizzazione 74
Folding and fibrillogenesis: clues from beta2-microglobulin. 73
The solution structure of human ß2-microglobulin reveals the prodromes of its amyloid transition 73
Truncation of the constant domain drives amyloid formation by immunoglobulin light chains 72
The effects of an ideal {beta}-turn on {beta}-2 microglobulin fold stability. 70
Properties of some variants of human beta 2- microglobulin and amyloidogenesis. 70
S-Homocysteinylation effects on transthyretin: Worsening of cardiomyopathy onset 70
Calcium Binds to Transthyretin with Low Affinity 69
Equilibrium unfolding thermodynamics of {beta}2-microglobulin analyzed through native-state H/D exchange. 69
Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation. 65
Effects of a vitamin E-modified dialyzer (Excebrane) on beta-2-microglobulin structure and removal. 65
The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease 65
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states 64
Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity 63
Design and Mechanistic Analysis of a Potent Bivalent Inhibitor of Transthyretin Amyloid Fibrillogenesis 62
Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers. 62
Targeting amyloid aggregation: An overview of strategies and mechanisms 62
Structure, function and amyloidogenic propensity of apolipoprotein A-I. 60
Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein A-I. 59
The workings of the amyloid diseases. 58
Fibrillar vs crystalline full-length beta-2-microglobulin studied by high-resolution solid-state NMR spectroscopy. 52
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 51
Totale 9.913
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Categoria #
all - tutte 40.629
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.629
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021136 0 0 0 0 0 0 0 0 0 69 55 12
2021/2022441 9 4 7 10 17 30 10 30 26 18 69 211
2022/20231.536 179 128 12 105 166 139 0 77 669 12 35 14
2023/2024540 87 108 28 31 50 128 16 19 5 23 30 15
2024/20251.653 49 120 52 49 53 78 69 116 427 46 189 405
2025/20263.560 293 318 463 500 485 167 676 144 321 193 0 0
Totale 10.196