BESIO, ROBERTA
 Distribuzione geografica
Continente #
NA - Nord America 2.476
AS - Asia 1.391
EU - Europa 1.063
SA - Sud America 263
Continente sconosciuto - Info sul continente non disponibili 159
AF - Africa 65
OC - Oceania 3
Totale 5.420
Nazione #
US - Stati Uniti d'America 2.419
CN - Cina 557
SG - Singapore 322
IE - Irlanda 259
BR - Brasile 205
VN - Vietnam 202
IT - Italia 197
HK - Hong Kong 161
RU - Federazione Russa 145
DE - Germania 103
FI - Finlandia 88
FR - Francia 60
GB - Regno Unito 54
ZA - Sudafrica 48
CA - Canada 39
UA - Ucraina 38
IN - India 37
SE - Svezia 29
BD - Bangladesh 20
CO - Colombia 18
AT - Austria 16
AR - Argentina 14
BE - Belgio 14
JP - Giappone 14
PL - Polonia 14
MX - Messico 12
NL - Olanda 11
EC - Ecuador 10
ID - Indonesia 10
PK - Pakistan 9
IQ - Iraq 8
TR - Turchia 8
CL - Cile 7
AL - Albania 5
ES - Italia 5
KR - Corea 5
CZ - Repubblica Ceca 4
MY - Malesia 4
SA - Arabia Saudita 4
CY - Cipro 3
DZ - Algeria 3
EG - Egitto 3
LT - Lituania 3
PH - Filippine 3
PY - Paraguay 3
VE - Venezuela 3
AU - Australia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BY - Bielorussia 2
EE - Estonia 2
GR - Grecia 2
IL - Israele 2
IR - Iran 2
JM - Giamaica 2
MA - Marocco 2
RO - Romania 2
RS - Serbia 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
EU - Europa 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
MM - Myanmar 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TG - Togo 1
TM - Turkmenistan 1
TN - Tunisia 1
TW - Taiwan 1
TZ - Tanzania 1
YE - Yemen 1
ZW - Zimbabwe 1
Totale 5.262
Città #
Dallas 475
Dublin 259
Chandler 221
San Jose 217
Ashburn 184
Singapore 179
Hong Kong 158
Beijing 131
Council Bluffs 129
Nanjing 69
Ho Chi Minh City 66
Los Angeles 66
Ann Arbor 56
Boardman 55
Jacksonville 54
Munich 50
Hanoi 49
Helsinki 48
Johannesburg 46
Lauterbourg 42
Pavia 38
Shanghai 37
Lawrence 35
Princeton 35
New York 33
Changsha 29
Medford 29
Nanchang 28
Redondo Beach 27
Santa Clara 27
Milan 26
Shenyang 26
Wilmington 25
Dearborn 23
Hebei 22
São Paulo 22
Moscow 20
Hangzhou 17
Buffalo 16
Fairfield 15
Jiaxing 15
Montreal 15
Naples 15
Turku 15
Brussels 14
Columbus 14
Tianjin 14
Houston 13
Orem 12
Rome 12
Tokyo 12
Da Nang 11
London 11
Warsaw 11
Woodbridge 11
Atlanta 10
San Francisco 10
The Dalles 10
Chennai 9
Nuremberg 9
Phoenix 9
Seattle 9
Washington 9
Amsterdam 8
Curitiba 8
Florence 8
Haiphong 8
Hải Dương 7
Toronto 7
Vienna 7
Belo Horizonte 6
Chicago 6
Guangzhou 6
Rio de Janeiro 6
Boston 5
Falkenstein 5
Medellín 5
Mexico City 5
Ningbo 5
Norwalk 5
Queens 5
Baghdad 4
Brasília 4
Brooklyn 4
Can Tho 4
Denver 4
Mumbai 4
Ninh Bình 4
Paris 4
Redwood City 4
Santiago 4
Stockholm 4
Tirana 4
Ankara 3
Bogotá 3
Buenos Aires 3
Fortaleza 3
Frankfurt am Main 3
Guarulhos 3
Hefei 3
Totale 3.535
Nome #
Osteogenesis Imperfecta: A Look into the Cerebellum of the Brtl Murine Model 327
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue 189
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency 186
A Mn(II)-Mn(II) center in human prolidase 171
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis 166
Altered cytoskeletal organization characterized lethal but not surviving Brtl+/- mice: insight on phenotypic variability in osteogenesis imperfecta 146
Differential response to intracellular stress in the skin from osteogenesis imperfecta Brtl mice with lethal and non lethal phenotype: a proteomic approach 145
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate 145
Partial rescue of biochemical parameters after hematopoietic stem cell transplantation in a patient with prolidase deficiency due to two novel PEPD mutations 144
4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion 138
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification 138
Severely impaired bone material quality in chihuahua zebrafish resembles classical dominant human Osteogenesis Imperfecta 135
Role of the advanced glycation end products receptor in Crohn’s disease inflammation 134
Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy 133
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development 130
Lack of prolidase causes a bone phenotype both in human and in mouse 128
A novel chemical chaperone ameliorates osteoblast homeostasis and extracellular matrix in osteogenesis imperfecta 126
Early Fracture Healing is Delayed in the Col1a2 +/G610C Osteogenesis Imperfecta Murine Model 123
Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes 122
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 122
Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective 115
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 115
Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV 115
Identifying the structure of the active sites of human recombinant prolidase 112
The administration of exogenous HSP47 as a collagen-specific therapeutic approach 109
Prolidase deficiency may be reversed by hematopietic stem cell transplantation: CE analysis of dipeptides in urine and monitoring of prolidase activity in blood. 100
Absence of Dipeptidyl Peptidase 3 increases oxidative stress and causes bone loss 99
Steady-state and pulse-chase analyses of fibrillar collagen 96
Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders 93
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta 92
Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing 91
CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta 89
Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function - A multi-omics study 88
Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm 88
Sc65-null mice provide evidence for a novel endoplasmic reticulum complex regulating collagen lysyl hydroxylation 86
First person - Roberta Besio 85
Dissecting the phenotypic variability of osteogenesis imperfecta 82
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury 81
Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis 81
Zebrafish Tric-b is required for skeletal development and bone cells differentiation 77
Treatment options for osteogenesis imperfecta 72
Outer Membrane Vesicles (OMVs) as Biomedical Tools and Their Relevance as Immune-Modulating Agents against H. pylori Infections: Current Status and Future Prospects 62
Sestrin2 drives ER-phagy in response to protein misfolding 57
TAPT1—at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta 53
The Highly Efficient Expression System of Recombinant Human Prolidase and the Effect of N-Terminal His-Tag on the Enzyme Activity 45
Intracellular and extracellular markers of lethality in osteogenesis imperfecta: A quantitative proteomic approach 36
Recombinant Prolidase Activates EGFR-Dependent Cell Growth in an Experimental Model of Inflammation in HaCaT Keratinocytes. Implication for Wound Healing 35
The Extracellular Matrix in Genetic Skeletal Disorders 30
Impact of oxygen–ozone mixture on cellular functions: a biochemical perspective across cell types 23
Lack of TRIC‐B dysregulates cytoskeleton assembly, trapping β‐catenin at osteoblast adhesion sites 23
Infectious seeds of valve calcification: Exploring the bacterial hypothesis in the pathogenesis of calcific aortic valve disease 18
OMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4‐PBA 14
Mineralised bone properties in a child with recessive osteogenesis imperfecta type XIV and in a conditional Tmem38b knockout murine model (Runx2-Cre; Tmem38b) 10
Totale 5.420
Categoria #
all - tutte 21.592
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.592


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022147 0 0 0 3 3 2 6 10 9 3 26 85
2022/2023662 57 62 5 37 59 57 1 39 303 7 14 21
2023/2024265 44 46 12 11 18 65 8 29 1 7 16 8
2024/2025821 24 51 29 12 44 27 41 65 212 30 96 190
2025/20262.320 125 227 526 206 217 79 324 117 199 162 85 53
2026/2027449 39 110 154 146 0 0 0 0 0 0 0 0
Totale 5.420