IRIS
BESIO, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 851
EU - Europa 494
AS - Asia 323
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 1.672
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Nazione #
US - Stati Uniti d'America 844
CN - Cina 317
IE - Irlanda 259
FI - Finlandia 60
IT - Italia 53
DE - Germania 34
UA - Ucraina 33
SE - Svezia 25
GB - Regno Unito 16
BE - Belgio 12
CA - Canada 6
IN - India 3
FR - Francia 2
AU - Australia 1
BR - Brasile 1
EU - Europa 1
ID - Indonesia 1
JP - Giappone 1
KR - Corea 1
MX - Messico 1
NZ - Nuova Zelanda 1
Totale 1.672
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Città #
Dublin 259
Chandler 221
Ashburn 69
Nanjing 69
Ann Arbor 56
Beijing 53
Jacksonville 53
Helsinki 35
Lawrence 35
Princeton 35
Medford 29
Nanchang 28
Shanghai 26
Shenyang 26
Changsha 25
Pavia 25
Wilmington 24
Dearborn 23
Hebei 22
Hangzhou 17
New York 16
Fairfield 15
Jiaxing 15
Tianjin 14
Brussels 12
Woodbridge 11
Milan 10
Boardman 9
Houston 8
Washington 7
Seattle 6
Los Angeles 5
Ningbo 5
Norwalk 5
Toronto 5
Redwood City 4
Guangzhou 3
Borås 2
Des Moines 2
Falkenstein 2
Genova 2
Jinan 2
Auckland 1
Berlin 1
Bhavnagar 1
Changchun 1
Chongqing 1
Ercolano 1
Hefei 1
Jakarta 1
Melbourne 1
Nagold 1
Orange 1
Pune 1
San Francisco 1
São Paulo 1
Walnut 1
Wuhan 1
Totale 1.306
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Nome #
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue 102
Partial rescue of biochemical parameters after hematopoietic stem cell transplantation in a patient with prolidase deficiency due to two novel PEPD mutations 95
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis 95
Differential response to intracellular stress in the skin from osteogenesis imperfecta Brtl mice with lethal and non lethal phenotype: a proteomic approach 78
Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy 70
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development 68
A Mn(II)-Mn(II) center in human prolidase 66
4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion 65
Lack of prolidase causes a bone phenotype both in human and in mouse 63
Role of the advanced glycation end products receptor in Crohn’s disease inflammation 61
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification 58
Prolidase deficiency may be reversed by hematopietic stem cell transplantation: CE analysis of dipeptides in urine and monitoring of prolidase activity in blood. 57
Altered cytoskeletal organization characterized lethal but not surviving Brtl+/- mice: insight on phenotypic variability in osteogenesis imperfecta 55
Severely impaired bone material quality in chihuahua zebrafish resembles classical dominant human Osteogenesis Imperfecta 53
Sc65-null mice provide evidence for a novel endoplasmic reticulum complex regulating collagen lysyl hydroxylation 52
Early Fracture Healing is Delayed in the Col1a2 +/G610C Osteogenesis Imperfecta Murine Model 52
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 51
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 49
Identifying the structure of the active sites of human recombinant prolidase 47
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate 46
Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes 46
Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective 44
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury 41
Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis 40
Steady-state and pulse-chase analyses of fibrillar collagen 40
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency 35
Treatment options for osteogenesis imperfecta 32
Absence of Dipeptidyl Peptidase 3 increases oxidative stress and causes bone loss 30
First person - Roberta Besio 30
Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders 27
Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm 27
Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing 26
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta 26
Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV 23
Intracellular and extracellular markers of lethality in osteogenesis imperfecta: A quantitative proteomic approach 20
Dissecting the phenotypic variability of osteogenesis imperfecta 14
The Highly Efficient Expression System of Recombinant Human Prolidase and the Effect of N-Terminal His-Tag on the Enzyme Activity 12
Zebrafish Tric-b is required for skeletal development and bone cells differentiation 10
Totale 1.806
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Categoria #
all - tutte 6.332
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 6.332
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20194 0 0 0 0 0 0 0 0 0 0 1 3
2019/2020424 88 173 7 7 2 10 5 30 19 37 25 21
2020/2021140 8 17 22 8 4 11 5 30 7 12 12 4
2021/2022158 2 4 5 3 3 2 6 10 9 3 26 85
2022/2023662 57 62 5 37 59 57 1 39 303 7 14 21
2023/2024241 44 46 12 11 18 65 8 29 1 7 0 0
Totale 1.806