IRIS
BESIO, ROBERTA
 Distribuzione geografica
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Continente #
NA - Nord America 920
EU - Europa 517
AS - Asia 384
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 1.825
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Nazione #
US - Stati Uniti d'America 910
CN - Cina 333
IE - Irlanda 259
FI - Finlandia 64
IT - Italia 55
DE - Germania 44
SG - Singapore 43
UA - Ucraina 33
SE - Svezia 25
GB - Regno Unito 17
BE - Belgio 13
CA - Canada 9
FR - Francia 3
IN - India 3
JP - Giappone 2
AL - Albania 1
AU - Australia 1
BR - Brasile 1
EU - Europa 1
ID - Indonesia 1
KR - Corea 1
LT - Lituania 1
MX - Messico 1
NZ - Nuova Zelanda 1
PL - Polonia 1
RU - Federazione Russa 1
VN - Vietnam 1
Totale 1.825
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Città #
Dublin 259
Chandler 221
Ashburn 69
Nanjing 69
Ann Arbor 56
Beijing 54
Jacksonville 53
Boardman 52
Helsinki 39
Lawrence 35
Princeton 35
Shanghai 33
Medford 29
Nanchang 28
Shenyang 26
Changsha 25
Pavia 25
Wilmington 24
Dearborn 23
Hebei 22
Singapore 21
Hangzhou 17
New York 16
Fairfield 15
Jiaxing 15
Tianjin 14
Brussels 13
Milan 12
Woodbridge 11
Los Angeles 10
Houston 8
Munich 8
Toronto 7
Washington 7
Seattle 6
Ningbo 5
Norwalk 5
Guangzhou 4
Redwood City 4
Dallas 3
Borås 2
Des Moines 2
Falkenstein 2
Genova 2
Hefei 2
Jinan 2
Auckland 1
Baqiao 1
Berlin 1
Bhavnagar 1
Changchun 1
Chongqing 1
Clifton 1
Ercolano 1
Forest City 1
Frankfurt am Main 1
Jakarta 1
Lincoln 1
London 1
Melbourne 1
Minden 1
Nagold 1
Newark 1
Orange 1
Ottawa 1
Piscataway 1
Pune 1
San Francisco 1
São Paulo 1
Tirana 1
Tokyo 1
Walnut 1
Warsaw 1
Wuhan 1
Xingtai 1
Totale 1.419
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Nome #
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue 106
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis 102
Partial rescue of biochemical parameters after hematopoietic stem cell transplantation in a patient with prolidase deficiency due to two novel PEPD mutations 100
Differential response to intracellular stress in the skin from osteogenesis imperfecta Brtl mice with lethal and non lethal phenotype: a proteomic approach 82
Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy 75
A Mn(II)-Mn(II) center in human prolidase 72
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development 72
4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion 68
Lack of prolidase causes a bone phenotype both in human and in mouse 66
Role of the advanced glycation end products receptor in Crohn’s disease inflammation 65
Altered cytoskeletal organization characterized lethal but not surviving Brtl+/- mice: insight on phenotypic variability in osteogenesis imperfecta 62
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification 61
Prolidase deficiency may be reversed by hematopietic stem cell transplantation: CE analysis of dipeptides in urine and monitoring of prolidase activity in blood. 59
Severely impaired bone material quality in chihuahua zebrafish resembles classical dominant human Osteogenesis Imperfecta 59
Early Fracture Healing is Delayed in the Col1a2 +/G610C Osteogenesis Imperfecta Murine Model 57
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 54
Sc65-null mice provide evidence for a novel endoplasmic reticulum complex regulating collagen lysyl hydroxylation 54
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 52
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate 51
Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes 51
Identifying the structure of the active sites of human recombinant prolidase 49
Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective 47
Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis 44
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury 43
Steady-state and pulse-chase analyses of fibrillar collagen 42
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency 38
Treatment options for osteogenesis imperfecta 36
Absence of Dipeptidyl Peptidase 3 increases oxidative stress and causes bone loss 33
First person - Roberta Besio 32
Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm 31
Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders 30
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta 29
Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing 28
Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV 27
Intracellular and extracellular markers of lethality in osteogenesis imperfecta: A quantitative proteomic approach 21
Dissecting the phenotypic variability of osteogenesis imperfecta 16
Zebrafish Tric-b is required for skeletal development and bone cells differentiation 14
The Highly Efficient Expression System of Recombinant Human Prolidase and the Effect of N-Terminal His-Tag on the Enzyme Activity 13
Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function - A multi-omics study 7
CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta 7
Outer Membrane Vesicles (OMVs) as Biomedical Tools and Their Relevance as Immune-Modulating Agents against H. pylori Infections: Current Status and Future Prospects 4
Recombinant Prolidase Activates EGFR-Dependent Cell Growth in an Experimental Model of Inflammation in HaCaT Keratinocytes. Implication for Wound Healing 4
TAPT1—at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta 2
Totale 1.965
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Categoria #
all - tutte 8.977
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8.977
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020149 0 0 0 0 2 10 5 30 19 37 25 21
2020/2021140 8 17 22 8 4 11 5 30 7 12 12 4
2021/2022158 2 4 5 3 3 2 6 10 9 3 26 85
2022/2023662 57 62 5 37 59 57 1 39 303 7 14 21
2023/2024265 44 46 12 11 18 65 8 29 1 7 16 8
2024/2025135 24 51 29 12 19 0 0 0 0 0 0 0
Totale 1.965