BESIO, ROBERTA
 Distribuzione geografica
Continente #
NA - Nord America 2.223
AS - Asia 1.386
EU - Europa 994
SA - Sud America 260
Continente sconosciuto - Info sul continente non disponibili 159
AF - Africa 65
OC - Oceania 3
Totale 5.090
Nazione #
US - Stati Uniti d'America 2.173
CN - Cina 556
SG - Singapore 321
IE - Irlanda 259
BR - Brasile 203
VN - Vietnam 202
HK - Hong Kong 161
IT - Italia 145
RU - Federazione Russa 145
DE - Germania 101
FI - Finlandia 88
FR - Francia 57
ZA - Sudafrica 48
GB - Regno Unito 44
UA - Ucraina 38
IN - India 37
CA - Canada 33
SE - Svezia 29
BD - Bangladesh 19
CO - Colombia 18
AT - Austria 16
AR - Argentina 14
BE - Belgio 14
JP - Giappone 14
PL - Polonia 14
MX - Messico 12
NL - Olanda 11
EC - Ecuador 10
ID - Indonesia 10
PK - Pakistan 9
IQ - Iraq 8
TR - Turchia 8
CL - Cile 6
AL - Albania 5
ES - Italia 5
KR - Corea 5
CZ - Repubblica Ceca 4
MY - Malesia 4
SA - Arabia Saudita 4
CY - Cipro 3
DZ - Algeria 3
EG - Egitto 3
LT - Lituania 3
PH - Filippine 3
PY - Paraguay 3
VE - Venezuela 3
AU - Australia 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BY - Bielorussia 2
GR - Grecia 2
IL - Israele 2
IR - Iran 2
JM - Giamaica 2
MA - Marocco 2
RO - Romania 2
RS - Serbia 2
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
EU - Europa 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KE - Kenya 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
MM - Myanmar 1
NG - Nigeria 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
PE - Perù 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TG - Togo 1
TM - Turkmenistan 1
TN - Tunisia 1
TW - Taiwan 1
TZ - Tanzania 1
YE - Yemen 1
ZW - Zimbabwe 1
Totale 4.932
Città #
Dallas 474
Dublin 259
Chandler 221
San Jose 182
Ashburn 180
Singapore 179
Hong Kong 158
Beijing 131
Council Bluffs 75
Nanjing 69
Ho Chi Minh City 66
Los Angeles 62
Ann Arbor 56
Boardman 55
Jacksonville 53
Hanoi 49
Helsinki 48
Munich 48
Johannesburg 46
Lauterbourg 42
Pavia 38
Shanghai 37
Lawrence 35
Princeton 35
New York 33
Changsha 29
Medford 29
Nanchang 28
Redondo Beach 27
Shenyang 26
Wilmington 24
Dearborn 23
Milan 23
Hebei 22
São Paulo 22
Santa Clara 21
Moscow 20
Hangzhou 17
Buffalo 16
Fairfield 15
Jiaxing 15
Montreal 15
Turku 15
Brussels 14
Columbus 14
Tianjin 14
Houston 13
Orem 12
Tokyo 12
Da Nang 11
Warsaw 11
Woodbridge 11
London 10
San Francisco 10
The Dalles 10
Atlanta 9
Chennai 9
Nuremberg 9
Amsterdam 8
Curitiba 8
Florence 8
Haiphong 8
Seattle 8
Washington 8
Hải Dương 7
Toronto 7
Vienna 7
Belo Horizonte 6
Chicago 6
Guangzhou 6
Naples 6
Rio de Janeiro 6
Rome 6
Boston 5
Falkenstein 5
Medellín 5
Mexico City 5
Ningbo 5
Norwalk 5
Phoenix 5
Baghdad 4
Can Tho 4
Denver 4
Mumbai 4
Ninh Bình 4
Redwood City 4
Santiago 4
Stockholm 4
Tirana 4
Ankara 3
Bogotá 3
Buenos Aires 3
Fortaleza 3
Frankfurt am Main 3
Guarulhos 3
Hefei 3
Hyderabad 3
Hòa Bình 3
Istanbul 3
Jakarta 3
Totale 3.396
Nome #
Osteogenesis Imperfecta: A Look into the Cerebellum of the Brtl Murine Model 318
A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency 183
Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue 180
A Mn(II)-Mn(II) center in human prolidase 165
Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis 159
Differential response to intracellular stress in the skin from osteogenesis imperfecta Brtl mice with lethal and non lethal phenotype: a proteomic approach 143
Partial rescue of biochemical parameters after hematopoietic stem cell transplantation in a patient with prolidase deficiency due to two novel PEPD mutations 138
Altered cytoskeletal organization characterized lethal but not surviving Brtl+/- mice: insight on phenotypic variability in osteogenesis imperfecta 136
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate 136
4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion 134
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification 131
Severely impaired bone material quality in chihuahua zebrafish resembles classical dominant human Osteogenesis Imperfecta 130
Role of the advanced glycation end products receptor in Crohn’s disease inflammation 129
Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy 129
Prolidase enzyme is required for extracellular matrix integrity and impacts on postnatal cerebellar cortex development 127
Lack of prolidase causes a bone phenotype both in human and in mouse 122
Early Fracture Healing is Delayed in the Col1a2 +/G610C Osteogenesis Imperfecta Murine Model 120
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype 117
Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes 116
A novel chemical chaperone ameliorates osteoblast homeostasis and extracellular matrix in osteogenesis imperfecta 115
In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knock-in murine model for classical, dominant osteogenesis imperfecta 110
Identifying the structure of the active sites of human recombinant prolidase 110
Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective 108
Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV 107
Prolidase deficiency may be reversed by hematopietic stem cell transplantation: CE analysis of dipeptides in urine and monitoring of prolidase activity in blood. 98
Absence of Dipeptidyl Peptidase 3 increases oxidative stress and causes bone loss 97
Steady-state and pulse-chase analyses of fibrillar collagen 92
The administration of exogenous HSP47 as a collagen-specific therapeutic approach 89
Targeting cellular stress in vitro improves osteoblast homeostasis, matrix collagen content and mineralization in two murine models of osteogenesis imperfecta 89
Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders 88
Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing 85
First person - Roberta Besio 83
CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta 81
Sc65-null mice provide evidence for a novel endoplasmic reticulum complex regulating collagen lysyl hydroxylation 81
Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm 81
Absence of TRIC-B from type XIV Osteogenesis Imperfecta osteoblasts alters cell adhesion and mitochondrial function - A multi-omics study 78
Dissecting the phenotypic variability of osteogenesis imperfecta 73
Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis 73
The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury 72
Zebrafish Tric-b is required for skeletal development and bone cells differentiation 71
Treatment options for osteogenesis imperfecta 68
Outer Membrane Vesicles (OMVs) as Biomedical Tools and Their Relevance as Immune-Modulating Agents against H. pylori Infections: Current Status and Future Prospects 60
TAPT1—at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta 49
Sestrin2 drives ER-phagy in response to protein misfolding 43
The Highly Efficient Expression System of Recombinant Human Prolidase and the Effect of N-Terminal His-Tag on the Enzyme Activity 39
Intracellular and extracellular markers of lethality in osteogenesis imperfecta: A quantitative proteomic approach 31
Recombinant Prolidase Activates EGFR-Dependent Cell Growth in an Experimental Model of Inflammation in HaCaT Keratinocytes. Implication for Wound Healing 29
Lack of TRIC‐B dysregulates cytoskeleton assembly, trapping β‐catenin at osteoblast adhesion sites 20
The Extracellular Matrix in Genetic Skeletal Disorders 18
Impact of oxygen–ozone mixture on cellular functions: a biochemical perspective across cell types 15
Infectious seeds of valve calcification: Exploring the bacterial hypothesis in the pathogenesis of calcific aortic valve disease 13
Mineralised bone properties in a child with recessive osteogenesis imperfecta type XIV and in a conditional Tmem38b knockout murine model (Runx2-Cre; Tmem38b) 7
OMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4‐PBA 4
Totale 5.090
Categoria #
all - tutte 20.297
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.297


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022156 0 4 5 3 3 2 6 10 9 3 26 85
2022/2023662 57 62 5 37 59 57 1 39 303 7 14 21
2023/2024265 44 46 12 11 18 65 8 29 1 7 16 8
2024/2025821 24 51 29 12 44 27 41 65 212 30 96 190
2025/20262.320 125 227 526 206 217 79 324 117 199 162 85 53
2026/2027119 39 80 0 0 0 0 0 0 0 0 0 0
Totale 5.090