CASTELLI, MATTEO
CASTELLI, MATTEO
DIPARTIMENTO DI CHIMICA
AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity
2022-01-01 Perna, Laura; Castelli, Matteo; Frasnetti, Elena; Romano, Lisa E L; Colombo, Giorgio; Prodromou, Chrisostomos; Chapple, J Paul
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations
2023-01-01 Castelli, Matteo; Marchetti, Filippo; Osuna, Sílvia; Oliveira, A. Sofia F.; Mulholland, Adrian J.; Serapian, Stefano A.; Colombo, Giorgio
Exploiting the folding and degradation machineries to target undruggable proteins: What can the computational approach tell us?
2021-01-01 Serapian, Stefano A; Castelli, Matteo; Marchetti, Filippo; Triveri, Alice; Colombo, Giorgio
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view
2023-01-01 Castelli, Matteo; Yan, Pengrong; Rodina, Anna; Digwal, Chander S.; Panchal, Palak; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio
Molecular Mechanisms of Chaperone Directed Protein Folding: Insights from Atomistic Simulations
2023-01-01 Castelli, Matteo; Magni, Andrea; Bonollo, Giorgio; Pavoni, Silvia; Frigerio, Francesco; Oliveira, A Sofia F; Cinquini, Fabrizio; Serapian, Stefano A; Colombo, Giorgio
New perspectives in cancer drug development: computational advances with an eye to design
2021-01-01 Castelli, M.; Serapian, S. A.; Marchetti, F.; Triveri, A.; Pirota, V.; Torielli, L.; Collina, S.; Doria, F.; Freccero, M.; Colombo, G.
NLRP3 monomer functional dynamics: From the effects of allosteric binding to implications for drug design
2023-01-01 Casali, Emanuele; Serapian, Stefano A.; Gianquinto, Eleonora; Castelli, Matteo; Bertinaria, Massimo; Spyrakis, Francesca; Colombo, Giorgio
N‐Glycosylation‐Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules
2024-01-01 Magni, Andrea; Sciva, Cristiano; Castelli, Matteo; Digwal, Chander S.; Rodina, Anna; Sharma, Sahil; Ochiana, Stefan; Patel, Hardik J.; Shah, Smit; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio
Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function
2023-01-01 Castelli, Matteo; Bhattacharya, Kaushik; Abboud, Ernest; Serapian, Stefano A; Picard, Didier; Colombo, Giorgio
Phosphorylation of the Hsp90 co-chaperone Hop changes its conformational dynamics and biological function
2022-01-01 Castelli, Matteo; Bhattacharya, Kaushik; Abboud, Ernest; Serapian, Stefano A.; Picard, Didier; Colombo, Giorgio
PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
2023-01-01 Backe, Sarah J.; Votra, SarahBeth D.; Stokes, Matthew P.; Sebestyén, Endre; Castelli, Matteo; Torielli, Luca; Colombo, Giorgio; Woodford, Mark R.; Mollapour, Mehdi; Bourboulia, Dimitra
Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes
2022-01-01 Triveri, Alice; Sanchez-Martin, Carlos; Torielli, Luca; Serapian, Stefano A; Marchetti, Filippo; D'Acerno, Giovanni; Pirota, Valentina; Castelli, Matteo; Moroni, Elisabetta; Ferraro, Mariarosaria; Quadrelli, Paolo; Rasola, Andrea; Colombo, Giorgio
Structures, dynamics, complexes, and functions: From classic computation to artificial intelligence
2024-01-01 Frasnetti, Elena; Magni, Andrea; Castelli, Matteo; Serapian, Stefano A.; Moroni, Elisabetta; Colombo, Giorgio
Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data
2022-01-01 Castelli, Matteo; Doria, Filippo; Freccero, Mauro; Colombo, Giorgio; Moroni, Elisabetta
The Dynamics of the Chaperone Folding Machinery
2024-01-18 Castelli, Matteo
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
2021-01-01 Woodford, Mark R.; Baker-Williams, Alexander J.; Sager, Rebecca A.; Backe, Sarah J.; Blanden, Adam R.; Hashmi, Fiza; Kancherla, Priyanka; Gori, Alessandro; Loiselle, David R.; Castelli, Matteo; Serapian, Stefano A.; Colombo, Giorgio; Haystead, Timothy A.; Jensen, Sandra M.; Stetler-Stevenson, William G.; Loh, Stewart N.; Schmidt, Laura S.; Marston Linehan, W.; Bah, Alaji; Bourboulia, Dimitra; Bratslavsky, Gennady; Mollapour, Mehdi
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
2021-01-01 Woodford, M. R.; Baker-Williams, A. J.; Sager, R. A.; Backe, S. J.; Blanden, A. R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D. R.; Castelli, M.; Serapian, S. A.; Colombo, G.; Haystead, T. A.; Jensen, S. M.; Stetler-Stevenson, W. G.; Loh, S. N.; Schmidt, L. S.; Linehan, W. M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity | 1-gen-2022 | Perna, Laura; Castelli, Matteo; Frasnetti, Elena; Romano, Lisa E L; Colombo, Giorgio; Prodromou, Chrisostomos; Chapple, J Paul | |
| Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations | 1-gen-2023 | Castelli, Matteo; Marchetti, Filippo; Osuna, Sílvia; Oliveira, A. Sofia F.; Mulholland, Adrian J.; Serapian, Stefano A.; Colombo, Giorgio | |
| Exploiting the folding and degradation machineries to target undruggable proteins: What can the computational approach tell us? | 1-gen-2021 | Serapian, Stefano A; Castelli, Matteo; Marchetti, Filippo; Triveri, Alice; Colombo, Giorgio | |
| How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view | 1-gen-2023 | Castelli, Matteo; Yan, Pengrong; Rodina, Anna; Digwal, Chander S.; Panchal, Palak; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio | |
| Molecular Mechanisms of Chaperone Directed Protein Folding: Insights from Atomistic Simulations | 1-gen-2023 | Castelli, Matteo; Magni, Andrea; Bonollo, Giorgio; Pavoni, Silvia; Frigerio, Francesco; Oliveira, A Sofia F; Cinquini, Fabrizio; Serapian, Stefano A; Colombo, Giorgio | |
| New perspectives in cancer drug development: computational advances with an eye to design | 1-gen-2021 | Castelli, M.; Serapian, S. A.; Marchetti, F.; Triveri, A.; Pirota, V.; Torielli, L.; Collina, S.; Doria, F.; Freccero, M.; Colombo, G. | |
| NLRP3 monomer functional dynamics: From the effects of allosteric binding to implications for drug design | 1-gen-2023 | Casali, Emanuele; Serapian, Stefano A.; Gianquinto, Eleonora; Castelli, Matteo; Bertinaria, Massimo; Spyrakis, Francesca; Colombo, Giorgio | |
| N‐Glycosylation‐Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules | 1-gen-2024 | Magni, Andrea; Sciva, Cristiano; Castelli, Matteo; Digwal, Chander S.; Rodina, Anna; Sharma, Sahil; Ochiana, Stefan; Patel, Hardik J.; Shah, Smit; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio | |
| Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function | 1-gen-2023 | Castelli, Matteo; Bhattacharya, Kaushik; Abboud, Ernest; Serapian, Stefano A; Picard, Didier; Colombo, Giorgio | |
| Phosphorylation of the Hsp90 co-chaperone Hop changes its conformational dynamics and biological function | 1-gen-2022 | Castelli, Matteo; Bhattacharya, Kaushik; Abboud, Ernest; Serapian, Stefano A.; Picard, Didier; Colombo, Giorgio | |
| PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling | 1-gen-2023 | Backe, Sarah J.; Votra, SarahBeth D.; Stokes, Matthew P.; Sebestyén, Endre; Castelli, Matteo; Torielli, Luca; Colombo, Giorgio; Woodford, Mark R.; Mollapour, Mehdi; Bourboulia, Dimitra | |
| Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes | 1-gen-2022 | Triveri, Alice; Sanchez-Martin, Carlos; Torielli, Luca; Serapian, Stefano A; Marchetti, Filippo; D'Acerno, Giovanni; Pirota, Valentina; Castelli, Matteo; Moroni, Elisabetta; Ferraro, Mariarosaria; Quadrelli, Paolo; Rasola, Andrea; Colombo, Giorgio | |
| Structures, dynamics, complexes, and functions: From classic computation to artificial intelligence | 1-gen-2024 | Frasnetti, Elena; Magni, Andrea; Castelli, Matteo; Serapian, Stefano A.; Moroni, Elisabetta; Colombo, Giorgio | |
| Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data | 1-gen-2022 | Castelli, Matteo; Doria, Filippo; Freccero, Mauro; Colombo, Giorgio; Moroni, Elisabetta | |
| The Dynamics of the Chaperone Folding Machinery | 18-gen-2024 | Castelli, Matteo | |
| The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect | 1-gen-2021 | Woodford, Mark R.; Baker-Williams, Alexander J.; Sager, Rebecca A.; Backe, Sarah J.; Blanden, Adam R.; Hashmi, Fiza; Kancherla, Priyanka; Gori, Alessandro; Loiselle, David R.; Castelli, Matteo; Serapian, Stefano A.; Colombo, Giorgio; Haystead, Timothy A.; Jensen, Sandra M.; Stetler-Stevenson, William G.; Loh, Stewart N.; Schmidt, Laura S.; Marston Linehan, W.; Bah, Alaji; Bourboulia, Dimitra; Bratslavsky, Gennady; Mollapour, Mehdi | |
| The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect | 1-gen-2021 | Woodford, M. R.; Baker-Williams, A. J.; Sager, R. A.; Backe, S. J.; Blanden, A. R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D. R.; Castelli, M.; Serapian, S. A.; Colombo, G.; Haystead, T. A.; Jensen, S. M.; Stetler-Stevenson, W. G.; Loh, S. N.; Schmidt, L. S.; Linehan, W. M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. |