Purpose: To evaluate macular and papillary parameters by spectral domain optical coherence tomography (SD-OCT) in children affected by mild-severe refractive errors. Methods: 310 eyes of 155 children (mean age: 9.04 years) were divided into 3 groups: group 0 (223 eyes with spherical equivalent (SE) between 3D and +3D); group 1 (31 myopic eyes with SE ≤ 3D); group 2 (56 hypermetropic eyes with SE ≥ 3D). All the subjects were assessed for retinal nerve fiber layer thickness (RNFLT), optic nerve head (ONH) parameters, ganglion cell complex thickness (GCCT) and macular thickness (MT) at 3 and 5 mm from the fovea by Optovue iVue SDOCT. Axial Length (AL) evaluation was assessed by optical biometer Zeiss IOL Master. Two-sided p-valuess < 0.05 were considered statistically significant. Results: Average, superior and inferior RNFLT were higher in group 2 compared to group 1, with values of 95, 98 and 92.5 lm (group 1) and 106, 107 and 104 lm (group 2) < 0.001). Rim and disc area were higher in group 2 compared to group 1, with values of 1.72 and 2.17 mm2 (group 1) and 2.16 and 2.48 mm2 (group 2) (p < 0.001). Average, superior and inferior GCCT were higher in group 2 compared to group 1, with values of 96, 97 and 97 lm (group 1) and 101, 100 and 101 lm (group 2) (p < 0.001). MT was higher in group 2 compared to group 1, in the quadrants superior (S), inferior (I), temporal (T) and nasal (N), both at 3 and 5 mm from the fovea, with values of 274 and 303 lm (group 1) and 305 and 318.5 lm (group 2) (S), 266 and 303 lm (group 1) and 295.5 and 315.5 lm (group 2) (I), 254 and 297 lm (group 1) and 254 and 307 lm (group 2) (T), 291 (group 1) and 317 (group 2) (N, 3 mm from the fovea) (p < 0.001). AL was significantly different between the groupsAL was significantly different between the groups (p < 0.00001). Conclusions: Mild-severe refractive errors affect morphometric parameters of the ONH and of the macula assessed by SD-OCT.
Macular and papillary morphometric evaluation with SD-OCT in children affected by mild-severe refractive errors
Bianchi, PE;Barilla, D;Bertone, C;Milano, G;Plaitano, C;Periti, F;Verticchio, A;
2018-01-01
Abstract
Purpose: To evaluate macular and papillary parameters by spectral domain optical coherence tomography (SD-OCT) in children affected by mild-severe refractive errors. Methods: 310 eyes of 155 children (mean age: 9.04 years) were divided into 3 groups: group 0 (223 eyes with spherical equivalent (SE) between 3D and +3D); group 1 (31 myopic eyes with SE ≤ 3D); group 2 (56 hypermetropic eyes with SE ≥ 3D). All the subjects were assessed for retinal nerve fiber layer thickness (RNFLT), optic nerve head (ONH) parameters, ganglion cell complex thickness (GCCT) and macular thickness (MT) at 3 and 5 mm from the fovea by Optovue iVue SDOCT. Axial Length (AL) evaluation was assessed by optical biometer Zeiss IOL Master. Two-sided p-valuess < 0.05 were considered statistically significant. Results: Average, superior and inferior RNFLT were higher in group 2 compared to group 1, with values of 95, 98 and 92.5 lm (group 1) and 106, 107 and 104 lm (group 2) < 0.001). Rim and disc area were higher in group 2 compared to group 1, with values of 1.72 and 2.17 mm2 (group 1) and 2.16 and 2.48 mm2 (group 2) (p < 0.001). Average, superior and inferior GCCT were higher in group 2 compared to group 1, with values of 96, 97 and 97 lm (group 1) and 101, 100 and 101 lm (group 2) (p < 0.001). MT was higher in group 2 compared to group 1, in the quadrants superior (S), inferior (I), temporal (T) and nasal (N), both at 3 and 5 mm from the fovea, with values of 274 and 303 lm (group 1) and 305 and 318.5 lm (group 2) (S), 266 and 303 lm (group 1) and 295.5 and 315.5 lm (group 2) (I), 254 and 297 lm (group 1) and 254 and 307 lm (group 2) (T), 291 (group 1) and 317 (group 2) (N, 3 mm from the fovea) (p < 0.001). AL was significantly different between the groupsAL was significantly different between the groups (p < 0.00001). Conclusions: Mild-severe refractive errors affect morphometric parameters of the ONH and of the macula assessed by SD-OCT.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
