IRIS
PREGNOLATO, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 2.676
EU - Europa 2.069
AS - Asia 1.343
Continente sconosciuto - Info sul continente non disponibili 9
SA - Sud America 5
OC - Oceania 3
AF - Africa 2
Totale 6.107
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Nazione #
US - Stati Uniti d'America 2.646
CN - Cina 1.250
IE - Irlanda 514
UA - Ucraina 418
FI - Finlandia 241
DE - Germania 228
IT - Italia 221
SE - Svezia 179
GB - Regno Unito 114
FR - Francia 112
SG - Singapore 57
CA - Canada 29
BE - Belgio 13
IN - India 11
JP - Giappone 10
EU - Europa 9
NL - Olanda 7
RU - Federazione Russa 7
IR - Iran 6
ES - Italia 4
VN - Vietnam 4
BG - Bulgaria 3
CH - Svizzera 3
CO - Colombia 3
LV - Lettonia 2
MU - Mauritius 2
MY - Malesia 2
NZ - Nuova Zelanda 2
AR - Argentina 1
AU - Australia 1
CL - Cile 1
GR - Grecia 1
IQ - Iraq 1
JO - Giordania 1
LT - Lituania 1
MX - Messico 1
NO - Norvegia 1
SA - Arabia Saudita 1
Totale 6.107
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Città #
Chandler 557
Dublin 512
Jacksonville 489
Nanjing 380
Ashburn 188
Boardman 167
Nanchang 160
Princeton 113
Wilmington 111
Changsha 110
Lawrence 108
Hebei 104
Beijing 98
Ann Arbor 89
Shenyang 87
Medford 86
Jiaxing 73
Tianjin 70
Helsinki 64
Milan 52
Hangzhou 49
Dearborn 48
Woodbridge 45
Shanghai 35
Singapore 32
New York 31
Toronto 26
Auburn Hills 20
Norwalk 20
Verona 20
Dallas 18
Seattle 16
Fairfield 14
Kunming 14
Des Moines 13
Brussels 12
Los Angeles 12
Tokyo 10
Binasco 8
Houston 8
Taizhou 8
Aurisina 7
Fuzhou 7
Hefei 6
Jinan 6
Phoenix 6
Washington 6
Hanover 5
Zhengzhou 5
Dijon 4
Dong Ket 4
Guangzhou 4
Lanzhou 4
Ningbo 4
Novokuznetsk 4
Pavia 4
Pisa 4
Pune 4
Rome 4
Bogotá 3
Lausanne 3
London 3
Madrid 3
Orange 3
Piscataway 3
San Francisco 3
Sissa 3
Capannori 2
Catania 2
Cologno Monzese 2
Delhi 2
Doncaster 2
Falkenstein 2
Gallo 2
Gilbert 2
Kharkov 2
Las Vegas 2
Leawood 2
Lurago D'erba 2
Naples 2
Ravenna 2
Rockville 2
Torricella 2
Valrico 2
Zanica 2
Acireale 1
Afragola 1
Amman 1
Amsterdam 1
Athens 1
Atlanta 1
Badalona 1
Baghdad 1
Baoding 1
Bari 1
Borås 1
Canberra 1
Cedar Knolls 1
Cerveteri 1
Changchun 1
Totale 4.240
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Nome #
Regioselettività di lipasi immobilizzate nell¿idrolisi di nucleosidi peracetilati 117
Transglicosilazione di Nucleosidi mediante Biocatalisi con Enzimi Immobilizzati e Stabilizzati 105
Sintesi di 2'-desossinucleosidi pirimidinici mediante transglicosilazione enzimatica 99
A facile synthesis of linear peracetylated oligosaccharides 92
3H-1,2-Dithiolo[3,4-b]pyridine-3-thione and its derivatives. Synthesis and Antimicrobial Activity 91
Sintesi one-pot di 2-acetamido-2-desossi-1,3,6-tri-O-acetil-alfa-D-glucopiranosio per la preparazione di N-acetil-D-lattosamina octaacetato 89
2',3'-Di-O-acyl-5-fluoronucleosides 86
One-pot Synthesis of 2'-Deoxyinosine and 2'-Deoxyguanosine by Transglycosylation Using Immobilized and Stabilized Enzymes 85
Immobilization Strategies to Improve Catalytic Properties of Hydrolases 84
Biodiversità nel microbioma umano: implicazioni sui processi cognitivi e coevolutivi 82
Tecnologie enzimatiche a basso impatto ambientale applicate alla sintesi farmaceutica 80
A process for the enantiomeric resolution of 1-substituted 2-(aminoethyl)-pyrrolidines by amidation with lipases 80
D-piranosamine peracetilate 3-monodeprotette e procedimento per la loro preparazione 76
Antimicrobial and genotoxic activities of N-(2-hydroxyethyl)-1,2-benzisothiazol-3(2H)-thione carbamic esters 75
Chemo-biocatalytic regioselective one-pot synthesis of different deprotected monosaccharides 75
A new synthesis of 2-naphtylmethyl-N-acetyl-alpha-D-lactosamine hexaacetate by regioselective enzymatic hydrolysis of peracetylated glucosamine 74
3H-[1,2]Dithiolo[3,4-b]pyridine-3-thione and its derivatives. Synthesis and antimicrobial activity 74
Synthesis and molucular modelling of novel HSV1 Uracil-DNA glycosylase inhibitors 73
"One-pot" synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-α-D-glucopyranose as intermediate for N-acetyl-α-D-lactosamine heptaacetate preparation 73
Biocatalysis and innovation: regio- and enantioselective enzymatic reactions 72
Immobilized Penicillin G Acylase as reactor and chiral selector in liquid chromatography 72
Ignazio Licata: The Latest Magna Graecia’s Natural Philosopher 72
1,2-Dithiolan-3-ones and derivatives structurally related to leinamycin. Synthesis and biological evaluation 71
Synthesis and molecular modeling of novel HSV1 uracil-DNA glycosylase inhibitors 70
“Process for the preparation of 3,6-di-O-acethyl-D-glycals via transacylation and regioselective enzymic hydrolysis” 70
Chemo-enzymatic synthesis of 5'-deoxynucleosides 70
Manufacture of (-)-(2S,3R)-2-amino-3-hydroxy-3-phenylpropionic acid and its derivatives with penicillin acylase 70
Highly enantiospecific oxyfunctionalization of nonactivated hydrocarbon sites by perflruoro-cis2-n-butyl-3-n-propyloxaziridine 68
Chemo-enzymatic process for preparing escitalopram 68
Synthesis and in Vitro Evaluation of Novel 6-Amino-(Ribo)- and -(Arabinofuranosyluracil) Derivatives as Antineoplastic and Antiviral Agents 67
Molecular modeling and synthesis of inhibitors of Herpes Simplex Virus type 1 uracil-DNA glycosylase 67
Process for preparation of (S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile 66
Transglycosylation of nucleosides by biocatalysis with immobilized and stabilized enzymes 66
Bioprocesses for the synthesis of nucleosides and nucleotides 66
Biological and anthropological-existential hypothesis on depression 65
Disposition of high dose busulfan in pediatric patients undergoing bone marrow transplantation 64
Spin Probe Analysis of Microtubules Structure and Formation 64
New N-alkyl-1,2-dihydro-2-thioxo-3-pyridinecarbothioamides as antituberculous agents with improved pharmacokinetics 64
Synthesis and in vitro activity of D- and L-5-(trifluoromethyl)uracil nucleoside derivatives 63
Procedimento per la preparazione di 3,6-di-O-acetil-D-glicali 63
Novel non-substrate inhibitors of human thymidine phosphorylase: prospect for the control of tumor-dependent angiogenesis 62
Enzymatic synthesis of cephalosporins. The immobilized acylase from Arthrobacter viscosus: A new useful biocatalyst. 62
5-(Trifluoromethyl)-beta-L-2'-deoxyuridine, the L-Enantiomer of Trifluorothymidine: Stereospecific Synthesis and Antiherpetic Evaluations 62
Developing a Novel Enzyme Immobilization Process by Activation of Epoxy Carriers with Glucosamine for Pharmaceutical and Food Applications 62
Selective interaction of the Human Immunodeficiency Virus type 1 reverse transcriptase nonnucleoside inhibitor Efavirenz and its thio-substituted analog with different enzyme-substrate complexes 61
Process for the selective enzymatic hydrolysis of nucleoside polyesters 61
Processo per la preparazione di cefonicid per via enzimatica 61
α-Amino-α´-halomethylketones: Synthetic Methodologies and Pharmaceutical Applications as Serine and Cysteine Protease Inhibitors 61
Enantioselective Enzymatic Hydrolysis of Racemic Glycidol Ester by Using Porcine Pancreas Lipase derivatives with Improved Catalytic Activity 60
Recombinant lipase from Candida rugosa as a tool for the regioselective hydrolysis of peracetylated pyrimidine nucleosides. A comparison with commercial non recombinant lipases 60
Synthesis of fludarabine 5'-monophosphate (FaraA 5’-MP) catalyzed by immobilized fruit fly deoxyribonucleoside kinase (Dm-dNK) 60
"Enantioselective Enzymatic Hydrolysis of Racemic Glycidol Ester by Using Immobilized Porcine Pancreatic Lipase Derivatives with Improved Catalytic Activity" 59
Biocatalisi e Innovazione: Reazioni Enzimatiche Regio- ed Enantioselettive 59
One-pot synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-apha-D-glucopyranose as intermediate for the synthesis of N-acetyl-D-lactosamine octaacetate 59
Molecular modelling and synthesis of inhibitors of herpes simplex virus type 1 Uracil-DNA glycosylase 58
Quantum Human and Animal Consciousness: a Concept Embracing Philosophy, Quantitative Molecular Biology and Mathematics 57
A Versatile Synthesis of 5'-Functionalized Nucleosides Through Regioselective Enzymatic Hydrolysis of Their Peracetylated Precursors 57
Immobilization and stabilization of recombinant multimeric uridine and purine nucleoside phosphorylases from Bacillus subtilis 57
Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis 56
Efficient biocatalyst for large-scale synthesisof cephalosporins, obtained by combining immobilizationand site-directed mutagenesis of penicillin acylase 56
Synthesis and in vitro anti-Mycobacterium activity of N-alkyl-1,2-dihydro-2-thioxo-3-pyridinecarbothioamides. Preliminary toxicity and pharmacokinetic evaluation 55
Immobilization of microbial penicillin-G-acylase on derivatized hydrophobic epoxide resin for the production of beta-lactam antibiotics. 55
The Non-Algorithmic Side of the Mind 54
Efficient Biocatalytic Cleavage and Recovery of Organic Substrates Supported on Soluble Polymers 53
Influence of the Enzyme Derivative Preparation and Substrate Structure on the Enantioselectivity of Penicillin G Acylase 53
Evidences Of New Biophysical Properties of Microtubules 53
Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives 53
Resolution of (±)-glycidol by using lipases immobilized on hydrophobic solid support 53
Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and D- and L-(beta)-dideoxynucleoside triphosphate analogs 52
Recombinant lipase from Candida rugosa for regioselective hydrolysis of peracetylated nucleosides. A comparison with commercial non-recombinant lipases 52
Synthesis of 2'-deoxynucleosides by transglycosylation with new immobilized and stabilized uridine phosphorylase and purine nucleoside phosphorylase 52
Major depression and bipolar disorder: The concept of symmetry breaking 51
Immobilized Enzymes for Resolution of Racemic Organic Substrates Linked to Soluble Polymers 50
Highly regioselective control of 1,2-addition of organolithiums to α,β-unsaturated compounds promoted by lithium bromide in 2-methyltetrahydrofuran: a facile and eco-friendly access to allylic alcohols and amines 50
Depression, osteoporosis, serotonin and cell membrane viscosity between biology and philosophical anthropology 50
Classificare gli organismi: DNA RNA e ricerca delle parentele tra specie 50
Resolution of (1)-glycidol by using lipases immobilized on hydrophobic solid support in: Lipases and Lipids: Structure, Function and Biotechnological Applications 50
Biodiversity in the Human Physical Body.The new frontiers of metagenomics and quorum sensing 48
Consciousness and Hallucination: molecular considerations and theoretical questions 47
Synthesis, Postmodification and Characterization of Linear Polystyrene-based Supports for the Interaction with Immobilized Biocatalysts 47
Enantioselective enzymatic hydrolysis of racemic glycidyl esters by using immobilized porcine pancreas lipase with improved catalytic properties. 46
High-performance liquid chromatography method for anlayzing the antiretroviral agent efavirenz (EFV, DMP 266) in human plasma 43
Enzymatic resolution of 5-hydroxy- and 8-hydroxy-2-tetralols using immobilized lipases 42
Fungicidal activity of some alkylthiosubstituted 2-iodo and 2-methylbenzanilides 41
Estrategias de Inmovilizacion para Mejorar las Propiedades Cataliticas de las Hidrolasas 41
Time for Quantum Consciousness 41
Quantum Neurophysics: From Non-Living Matter to Quantum Neurobiology and Psychopathology 39
Hepatitis C virus IRES inhibitors: development and future perspectives 38
The Interactome Hypothesis of Depression 37
Looking for the Physical, Logical, and Computational Roots of the Mind 36
Exploring Structural and Dynamical Properties of Microtubules by Means of Artificial Neural Networks 35
On the Possible Existence of Quantum Consciousness After Brain Death 35
Immobilization of neutral protease from Bacillus subtilis for regioselective hydrolysis of acetylated nucleosides: Application to capecitabine synthesis 34
Can Qualitative Biophysics Solve the Hard Problem? 32
On the Reaction between 3H-1,2-Dithiolo [3,4-b]-pyridine-3-thione and Primary Alkyl and Arylalkylamines 31
Electromagnetic homeostasis and the role of low-amplitude electromagnetic fields on life organization 30
Potentiation of Inhibition of Wild Type and Mutant HIV-1 Reverse Transcriptases by Combinations of Non-Nucleoside Inhibitors and D- and L-(b)-Dideoxynucleoside Triphosphate Analogs 29
A Computational Simulation of the Interaction Between Immune and Neuroendocrine Systems 29
Quantum logic of the unconscious and schizophrenia 27
Computational Study on the Binding Affinity Between Microtubules and Consciousness-Altering Substances 25
Totale 5.957
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Categoria #
all - tutte 22.058
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.058
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020515 0 0 0 87 9 102 26 100 11 128 44 8
2020/2021782 89 71 23 77 7 101 15 123 24 111 102 39
2021/2022550 12 6 27 8 18 25 11 30 20 34 112 247
2022/20231.535 175 109 13 132 162 179 1 86 616 4 32 26
2023/2024560 78 92 18 42 51 155 17 41 3 16 21 26
2024/2025218 16 156 45 1 0 0 0 0 0 0 0 0
Totale 6.208