IRIS
KIEL, CHRISTINA
 Distribuzione geografica
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Continente #
EU - Europa 363
NA - Nord America 260
AS - Asia 76
SA - Sud America 4
Totale 703
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Nazione #
IE - Irlanda 316
US - Stati Uniti d'America 258
CN - Cina 52
FI - Finlandia 18
SG - Singapore 17
IT - Italia 12
DE - Germania 9
BR - Brasile 4
IL - Israele 4
IN - India 3
AT - Austria 2
GB - Regno Unito 2
MT - Malta 2
CA - Canada 1
EE - Estonia 1
FR - Francia 1
MX - Messico 1
Totale 703
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Città #
Dublin 316
Ashburn 97
Boardman 61
Shanghai 33
Helsinki 18
Washington 15
Singapore 9
New York 8
Falkenstein 7
Milan 7
Juiz de Fora 4
Seattle 4
Los Angeles 3
Rehovot 3
Afragola 2
Birkirkara 2
Dallas 2
Dorking 2
Mumbai 2
Santa Clara 2
Anshan 1
Beijing 1
Forest City 1
Frankfurt am Main 1
Guangzhou 1
Hefei 1
Jiangmen 1
Jinan 1
Nanyang 1
Naples 1
Rishon LeTsiyyon 1
Rome 1
Silao 1
Tallinn 1
Toronto 1
Vienna 1
Zhengzhou 1
Totale 614
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Nome #
Complexities in Quantitative Systems Analysis of Signaling Networks 25
A detailed thermodynamic analysis of ras/effector complex interfaces 25
A RAC-GEF network critical for early intestinal tumourigenesis 24
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network 22
Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling 22
Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses 22
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 21
Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations 20
Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex 20
Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks 19
Combining Gene-Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration 19
A Comprehensive View of the β-Arrestinome 18
Analyzing protein interaction networks using structural information 18
Challenges ahead in signal transduction: MAPK as an example 17
Association rate constants of ras-effector interactions are evolutionarily conserved 17
Affinity Can have Many Faces: Thermodynamic and Kinetic Properties of Ras-Effector Complex Formation 16
Interaction Dynamics Determine Signaling and Output Pathway Responses 15
Network pharmacology: curing causal mechanisms instead of treating symptoms 15
Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context 14
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 14
HOMELETTE: a unified interface to homology modelling software 14
A genome-wide Ras-effector interaction network 13
Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP 13
Insights into protein-protein binding by binding free energy calculation and free energy decomposition for the Ras-Raf and Ras-RalGDS complexes 13
Engineering of Biological Pathways: Complex Formation and Signal Transduction 12
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D 12
Cell Adhesion Molecules in Normal Skin and Melanoma 12
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes 12
The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF 11
The Ins and Outs of RAS Effector Complexes 11
Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues 11
TAPAS: tools to assist the targeted protein quantification of human alternative splice variants 10
Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines 10
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain 10
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain 10
Improved binding of raf to Ras.GDP is correlated with biological activity 10
Integration of protein abundance and structure data reveals competition in the ErbB signaling network 10
Shaping dots and lines: adding modularity into protein interaction networks using structural information 9
Prediction of Ras-effector interactions using position energy matrices 9
Protein design in biological networks: from manipulating the input to modifying the output 9
Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways 9
Recognizing and defining true Ras binding domains I: biochemical analysis 9
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations 9
Systems level expression correlation of Ras GTPase regulators 8
Engineering signal transduction pathways 8
Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage 8
From oncogenic mutation to dynamic code 8
Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins 8
Reconstruction and analysis of a large-scale binary Ras-effector signaling network 8
Structures in systems biology 8
SAPIN: a framework for the structural analysis of protein interaction networks 8
VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants 8
Simple and complex retinal dystrophies are associated with profoundly different disease networks 7
Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks 7
Opportunities and Challenges of Whole-Cell and -Tissue Simulations of the Outer Retina in Health and Disease 7
Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering 7
Repository of proposed pathways and protein-protein interaction networks in age-related macular degeneration 7
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations 7
SnapShot: APC/T Cell Immune Checkpoints 6
Prediction of Ras-effector interactions using position energy matrices 5
Structural and functional protein network analyses predict novel signaling functions for rhodopsin 5
Classification of GTP-dependent K-Ras4B active and inactive conformational states 2
Analysis of context-specific KRAS–effector (sub)complexes in Caco-2 cells 2
“Energetics of the outer retina I: Estimates of nutrient exchange and ATP generation” 2
Structure-based prediction of Ras-effector binding affinities and design of “branchegetic” interface mutations 2
null 1
Totale 770
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Categoria #
all - tutte 8.152
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8.152
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/2023376 0 0 0 0 0 0 64 0 310 0 2 0
2023/2024241 1 19 23 21 49 80 32 3 0 7 2 4
2024/2025153 23 68 4 11 3 36 8 0 0 0 0 0
Totale 770