IRIS
KIEL, CHRISTINA
 Distribuzione geografica
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Continente #
EU - Europa 332
NA - Nord America 189
AS - Asia 52
SA - Sud America 4
Totale 577
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Nazione #
IE - Irlanda 316
US - Stati Uniti d'America 188
CN - Cina 32
SG - Singapore 16
IT - Italia 5
BR - Brasile 4
IL - Israele 3
AT - Austria 2
DE - Germania 2
FI - Finlandia 2
GB - Regno Unito 2
MT - Malta 2
FR - Francia 1
IN - India 1
MX - Messico 1
Totale 577
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Città #
Dublin 316
Ashburn 97
Shanghai 31
Washington 15
Singapore 9
New York 8
Juiz de Fora 4
Los Angeles 3
Rehovot 3
Seattle 3
Afragola 2
Birkirkara 2
Dorking 2
Helsinki 2
Beijing 1
Forest City 1
Frankfurt am Main 1
Naples 1
Rome 1
Silao 1
Vienna 1
Totale 504
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Nome #
Complexities in Quantitative Systems Analysis of Signaling Networks 23
A detailed thermodynamic analysis of ras/effector complex interfaces 22
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 19
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network 19
A RAC-GEF network critical for early intestinal tumourigenesis 19
Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex 18
Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations 17
Combining Gene-Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration 17
Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses 17
Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling 16
Analyzing protein interaction networks using structural information 16
Challenges ahead in signal transduction: MAPK as an example 15
Association rate constants of ras-effector interactions are evolutionarily conserved 15
A Comprehensive View of the β-Arrestinome 14
Affinity Can have Many Faces: Thermodynamic and Kinetic Properties of Ras-Effector Complex Formation 14
Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks 13
HOMELETTE: a unified interface to homology modelling software 13
Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context 12
Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP 12
Interaction Dynamics Determine Signaling and Output Pathway Responses 11
A genome-wide Ras-effector interaction network 11
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 11
Engineering of Biological Pathways: Complex Formation and Signal Transduction 10
The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF 10
The Ins and Outs of RAS Effector Complexes 10
Network pharmacology: curing causal mechanisms instead of treating symptoms 10
Cell Adhesion Molecules in Normal Skin and Melanoma 10
Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues 10
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D 9
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain 9
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain 9
Improved binding of raf to Ras.GDP is correlated with biological activity 9
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes 9
Integration of protein abundance and structure data reveals competition in the ErbB signaling network 9
Shaping dots and lines: adding modularity into protein interaction networks using structural information 8
TAPAS: tools to assist the targeted protein quantification of human alternative splice variants 8
Prediction of Ras-effector interactions using position energy matrices 8
Insights into protein-protein binding by binding free energy calculation and free energy decomposition for the Ras-Raf and Ras-RalGDS complexes 8
Protein design in biological networks: from manipulating the input to modifying the output 8
Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways 8
Recognizing and defining true Ras binding domains I: biochemical analysis 8
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations 8
Engineering signal transduction pathways 7
Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage 7
From oncogenic mutation to dynamic code 7
Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins 7
Reconstruction and analysis of a large-scale binary Ras-effector signaling network 7
Structures in systems biology 7
SAPIN: a framework for the structural analysis of protein interaction networks 7
VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants 7
Simple and complex retinal dystrophies are associated with profoundly different disease networks 6
Systems level expression correlation of Ras GTPase regulators 6
Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks 6
Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines 6
Opportunities and Challenges of Whole-Cell and -Tissue Simulations of the Outer Retina in Health and Disease 6
Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering 6
Repository of proposed pathways and protein-protein interaction networks in age-related macular degeneration 6
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations 6
SnapShot: APC/T Cell Immune Checkpoints 5
Prediction of Ras-effector interactions using position energy matrices 4
Structural and functional protein network analyses predict novel signaling functions for rhodopsin 4
null 1
Totale 640
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Categoria #
all - tutte 5.494
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.494
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/2023376 0 0 0 0 0 0 64 0 310 0 2 0
2023/2024241 1 19 23 21 49 80 32 3 0 7 2 4
2024/202523 23 0 0 0 0 0 0 0 0 0 0 0
Totale 640