IRIS
KIEL, CHRISTINA
 Distribuzione geografica
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Continente #
NA - Nord America 1.234
AS - Asia 981
EU - Europa 690
SA - Sud America 179
Continente sconosciuto - Info sul continente non disponibili 69
AF - Africa 29
OC - Oceania 3
Totale 3.185
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Nazione #
US - Stati Uniti d'America 1.192
IE - Irlanda 316
SG - Singapore 296
CN - Cina 211
HK - Hong Kong 196
BR - Brasile 135
RU - Federazione Russa 122
VN - Vietnam 114
FR - Francia 60
DE - Germania 55
GB - Regno Unito 42
IN - India 40
FI - Finlandia 29
IT - Italia 24
BD - Bangladesh 20
AR - Argentina 19
IQ - Iraq 17
CA - Canada 16
PK - Pakistan 14
TR - Turchia 12
ZA - Sudafrica 12
SA - Arabia Saudita 10
MX - Messico 9
PL - Polonia 8
ID - Indonesia 7
UZ - Uzbekistan 7
EC - Ecuador 6
JP - Giappone 6
AT - Austria 5
AZ - Azerbaigian 5
ES - Italia 5
MA - Marocco 5
PH - Filippine 5
SE - Svezia 5
UA - Ucraina 5
CO - Colombia 4
HN - Honduras 4
IL - Israele 4
NL - Olanda 4
CL - Cile 3
JO - Giordania 3
KE - Kenya 3
UY - Uruguay 3
VE - Venezuela 3
AU - Australia 2
BO - Bolivia 2
DZ - Algeria 2
ET - Etiopia 2
GT - Guatemala 2
JM - Giamaica 2
KW - Kuwait 2
KZ - Kazakistan 2
MT - Malta 2
MY - Malesia 2
NI - Nicaragua 2
PE - Perù 2
PY - Paraguay 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
AE - Emirati Arabi Uniti 1
AO - Angola 1
BB - Barbados 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
BZ - Belize 1
CH - Svizzera 1
CR - Costa Rica 1
CY - Cipro 1
EE - Estonia 1
EG - Egitto 1
GD - Grenada 1
GR - Grecia 1
KG - Kirghizistan 1
KR - Corea 1
LB - Libano 1
LT - Lituania 1
NP - Nepal 1
PA - Panama 1
QA - Qatar 1
RS - Serbia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TO - Tonga 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 3.117
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Città #
Dublin 316
San Jose 216
Hong Kong 195
Ashburn 191
Dallas 122
Singapore 108
Council Bluffs 107
Boardman 61
Los Angeles 56
Lauterbourg 55
New York 36
Munich 33
Shanghai 33
Beijing 32
Ho Chi Minh City 31
Columbus 27
Hanoi 25
Buffalo 24
Redondo Beach 24
Helsinki 23
Moscow 21
The Dalles 18
Santa Clara 17
Washington 15
São Paulo 14
Brooklyn 13
Falkenstein 12
Hải Dương 9
Johannesburg 8
Milan 8
Phoenix 8
Warsaw 8
Chennai 7
Chicago 7
Orem 7
Denver 6
Tashkent 6
Tokyo 6
Turku 6
Baku 5
Da Nang 5
Jeddah 5
Juiz de Fora 5
Maringá 5
Montreal 5
Seattle 5
Stockholm 5
Baghdad 4
Boston 4
Karbala 4
Raleigh 4
San Francisco 4
Secaucus 4
Tianjin 4
Amman 3
Ankara 3
Atlanta 3
Cape Town 3
Charlotte 3
Duque de Caxias 3
Haiphong 3
Istanbul 3
Karachi 3
London 3
Manchester 3
Montevideo 3
Mumbai 3
Nairobi 3
Ninh Bình 3
Rehovot 3
Riyadh 3
Shijiazhuang 3
St Petersburg 3
Thái Bình 3
Toronto 3
Addis Ababa 2
Afragola 2
Ahmedabad 2
Almaty 2
Amsterdam 2
Anápolis 2
Barbacena 2
Bauru 2
Birkirkara 2
Biên Hòa 2
Brasília 2
Bryansk 2
Cebu City 2
Concord 2
Córdoba 2
Delhi 2
Dorking 2
Duhok 2
Erbil 2
Guangzhou 2
Hefei 2
Hortolândia 2
Jaipur 2
Jinan 2
Kuwait City 2
Totale 2.092
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Nome #
A RAC-GEF network critical for early intestinal tumourigenesis 76
A detailed thermodynamic analysis of ras/effector complex interfaces 74
Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context 72
Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations 71
Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling 71
A Comprehensive View of the β-Arrestinome 70
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network 70
Complexities in Quantitative Systems Analysis of Signaling Networks 67
Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks 63
Combining Gene-Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration 63
Challenges ahead in signal transduction: MAPK as an example 62
Cell Adhesion Molecules in Normal Skin and Melanoma 62
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 61
Network pharmacology: curing causal mechanisms instead of treating symptoms 60
Analyzing protein interaction networks using structural information 60
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain 59
Insights into protein-protein binding by binding free energy calculation and free energy decomposition for the Ras-Raf and Ras-RalGDS complexes 58
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 57
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D 54
A genome-wide Ras-effector interaction network 54
Association rate constants of ras-effector interactions are evolutionarily conserved 54
VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants 54
Affinity Can have Many Faces: Thermodynamic and Kinetic Properties of Ras-Effector Complex Formation 53
The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF 51
Engineering of Biological Pathways: Complex Formation and Signal Transduction 50
Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses 49
Engineering signal transduction pathways 48
Improved binding of raf to Ras.GDP is correlated with biological activity 48
Analysis of context-specific KRAS–effector (sub)complexes in Caco-2 cells 48
Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex 48
Classification of GTP-dependent K-Ras4B active and inactive conformational states 47
Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP 47
Simple and complex retinal dystrophies are associated with profoundly different disease networks 46
Interaction Dynamics Determine Signaling and Output Pathway Responses 46
Prediction of Ras-effector interactions using position energy matrices 46
Reconstruction and analysis of a large-scale binary Ras-effector signaling network 46
Shaping dots and lines: adding modularity into protein interaction networks using structural information 45
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes 45
Systems level expression correlation of Ras GTPase regulators 44
Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines 43
Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins 43
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain 42
Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering 42
The Ins and Outs of RAS Effector Complexes 41
Integration of protein abundance and structure data reveals competition in the ErbB signaling network 41
Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage 40
TAPAS: tools to assist the targeted protein quantification of human alternative splice variants 39
Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues 39
Structure-based prediction of Ras-effector binding affinities and design of “branchegetic” interface mutations 39
Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks 38
Repository of proposed pathways and protein-protein interaction networks in age-related macular degeneration 38
Structures in systems biology 38
HOMELETTE: a unified interface to homology modelling software 38
Protein design in biological networks: from manipulating the input to modifying the output 37
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations 37
Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways 36
Recognizing and defining true Ras binding domains I: biochemical analysis 35
Structural and functional protein network analyses predict novel signaling functions for rhodopsin 34
From oncogenic mutation to dynamic code 33
Opportunities and Challenges of Whole-Cell and -Tissue Simulations of the Outer Retina in Health and Disease 33
SAPIN: a framework for the structural analysis of protein interaction networks 33
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations 33
SnapShot: APC/T Cell Immune Checkpoints 32
“Energetics of the outer retina I: Estimates of nutrient exchange and ATP generation” 32
“Energetics of the outer retina II: Calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of cellular processes” 32
Prediction of Ras-effector interactions using position energy matrices 17
null 1
Totale 3.185
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Categoria #
all - tutte 19.218
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.218
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/2023376 0 0 0 0 0 0 64 0 310 0 2 0
2023/2024241 1 19 23 21 49 80 32 3 0 7 2 4
2024/2025724 23 68 4 11 3 36 46 37 191 18 69 218
2025/20261.729 131 148 167 147 193 68 321 53 159 208 90 44
2026/2027115 23 92 0 0 0 0 0 0 0 0 0 0
Totale 3.185