IRIS
KIEL, CHRISTINA
 Distribuzione geografica
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Continente #
NA - Nord America 985
AS - Asia 957
EU - Europa 683
SA - Sud America 178
AF - Africa 29
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 2.836
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Nazione #
US - Stati Uniti d'America 957
IE - Irlanda 316
SG - Singapore 284
CN - Cina 203
HK - Hong Kong 196
BR - Brasile 134
RU - Federazione Russa 122
VN - Vietnam 114
FR - Francia 60
DE - Germania 55
GB - Regno Unito 41
IN - India 40
FI - Finlandia 29
AR - Argentina 19
BD - Bangladesh 19
IT - Italia 18
IQ - Iraq 17
PK - Pakistan 14
ZA - Sudafrica 12
TR - Turchia 11
CA - Canada 10
SA - Arabia Saudita 10
MX - Messico 9
PL - Polonia 8
ID - Indonesia 7
UZ - Uzbekistan 7
EC - Ecuador 6
JP - Giappone 6
AT - Austria 5
AZ - Azerbaigian 5
ES - Italia 5
MA - Marocco 5
SE - Svezia 5
UA - Ucraina 5
CO - Colombia 4
IL - Israele 4
NL - Olanda 4
PH - Filippine 4
CL - Cile 3
JO - Giordania 3
KE - Kenya 3
UY - Uruguay 3
VE - Venezuela 3
AU - Australia 2
BO - Bolivia 2
DZ - Algeria 2
ET - Etiopia 2
HN - Honduras 2
KW - Kuwait 2
KZ - Kazakistan 2
MT - Malta 2
MY - Malesia 2
PE - Perù 2
PY - Paraguay 2
TN - Tunisia 2
AE - Emirati Arabi Uniti 1
AO - Angola 1
BB - Barbados 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
BZ - Belize 1
CH - Svizzera 1
CR - Costa Rica 1
CY - Cipro 1
EE - Estonia 1
EG - Egitto 1
GD - Grenada 1
GR - Grecia 1
JM - Giamaica 1
KG - Kirghizistan 1
KR - Corea 1
LB - Libano 1
LT - Lituania 1
NI - Nicaragua 1
PA - Panama 1
QA - Qatar 1
RS - Serbia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TO - Tonga 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 2.836
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Città #
Dublin 316
Hong Kong 195
Ashburn 180
San Jose 173
Dallas 118
Singapore 103
Boardman 61
Los Angeles 56
Lauterbourg 55
Munich 33
Shanghai 33
New York 32
Beijing 31
Ho Chi Minh City 31
Hanoi 25
Buffalo 24
Redondo Beach 24
Helsinki 23
Moscow 21
The Dalles 18
Washington 15
São Paulo 14
Brooklyn 12
Falkenstein 12
Hải Dương 9
Santa Clara 9
Johannesburg 8
Milan 8
Warsaw 8
Chennai 7
Chicago 7
Council Bluffs 7
Tashkent 6
Tokyo 6
Turku 6
Baku 5
Da Nang 5
Jeddah 5
Juiz de Fora 5
Orem 5
Phoenix 5
Seattle 5
Stockholm 5
Baghdad 4
Boston 4
Denver 4
Karbala 4
Maringá 4
Raleigh 4
Secaucus 4
Tianjin 4
Amman 3
Ankara 3
Atlanta 3
Cape Town 3
Charlotte 3
Duque de Caxias 3
Haiphong 3
Istanbul 3
Karachi 3
London 3
Manchester 3
Montevideo 3
Montreal 3
Mumbai 3
Nairobi 3
Ninh Bình 3
Rehovot 3
Riyadh 3
Shijiazhuang 3
St Petersburg 3
Thái Bình 3
Toronto 3
Addis Ababa 2
Afragola 2
Ahmedabad 2
Almaty 2
Amsterdam 2
Anápolis 2
Barbacena 2
Bauru 2
Birkirkara 2
Biên Hòa 2
Brasília 2
Bryansk 2
Cebu City 2
Concord 2
Córdoba 2
Delhi 2
Dorking 2
Duhok 2
Erbil 2
Guangzhou 2
Hefei 2
Hortolândia 2
Jaipur 2
Jinan 2
Kuwait City 2
Lauro de Freitas 2
Londrina 2
Totale 1.878
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Nome #
A RAC-GEF network critical for early intestinal tumourigenesis 76
A detailed thermodynamic analysis of ras/effector complex interfaces 73
Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context 68
A Comprehensive View of the β-Arrestinome 68
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network 68
Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling 66
Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations 65
Complexities in Quantitative Systems Analysis of Signaling Networks 64
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 59
Cell Adhesion Molecules in Normal Skin and Melanoma 57
Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks 56
Combining Gene-Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration 56
Analyzing protein interaction networks using structural information 55
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain 54
Challenges ahead in signal transduction: MAPK as an example 53
Insights into protein-protein binding by binding free energy calculation and free energy decomposition for the Ras-Raf and Ras-RalGDS complexes 53
Association rate constants of ras-effector interactions are evolutionarily conserved 53
Affinity Can have Many Faces: Thermodynamic and Kinetic Properties of Ras-Effector Complex Formation 52
A genome-wide Ras-effector interaction network 51
VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants 51
Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa 50
Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses 49
Network pharmacology: curing causal mechanisms instead of treating symptoms 48
Improved binding of raf to Ras.GDP is correlated with biological activity 47
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D 46
The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF 46
Analysis of context-specific KRAS–effector (sub)complexes in Caco-2 cells 46
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes 44
Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex 44
Classification of GTP-dependent K-Ras4B active and inactive conformational states 43
Engineering of Biological Pathways: Complex Formation and Signal Transduction 42
Shaping dots and lines: adding modularity into protein interaction networks using structural information 42
Engineering signal transduction pathways 42
Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins 42
Simple and complex retinal dystrophies are associated with profoundly different disease networks 40
Interaction Dynamics Determine Signaling and Output Pathway Responses 39
Prediction of Ras-effector interactions using position energy matrices 39
Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP 39
Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage 38
TAPAS: tools to assist the targeted protein quantification of human alternative splice variants 37
Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines 37
The Ins and Outs of RAS Effector Complexes 37
Reconstruction and analysis of a large-scale binary Ras-effector signaling network 37
Integration of protein abundance and structure data reveals competition in the ErbB signaling network 37
HOMELETTE: a unified interface to homology modelling software 37
Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks 36
Repository of proposed pathways and protein-protein interaction networks in age-related macular degeneration 36
Systems level expression correlation of Ras GTPase regulators 35
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain 35
Protein design in biological networks: from manipulating the input to modifying the output 34
Recognizing and defining true Ras binding domains I: biochemical analysis 34
Predicted 'wiring landscape' of Ras-effector interactions in 29 human tissues 33
Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering 33
Structures in systems biology 33
Structural and functional protein network analyses predict novel signaling functions for rhodopsin 33
“Energetics of the outer retina II: Calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of cellular processes” 32
Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways 31
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations 31
SnapShot: APC/T Cell Immune Checkpoints 30
SAPIN: a framework for the structural analysis of protein interaction networks 30
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations 30
Opportunities and Challenges of Whole-Cell and -Tissue Simulations of the Outer Retina in Health and Disease 29
“Energetics of the outer retina I: Estimates of nutrient exchange and ATP generation” 29
Structure-based prediction of Ras-effector binding affinities and design of “branchegetic” interface mutations 29
From oncogenic mutation to dynamic code 27
Prediction of Ras-effector interactions using position energy matrices 17
null 1
Totale 2.904
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Categoria #
all - tutte 16.650
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.650
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/2023376 0 0 0 0 0 0 64 0 310 0 2 0
2023/2024241 1 19 23 21 49 80 32 3 0 7 2 4
2024/2025724 23 68 4 11 3 36 46 37 191 18 69 218
2025/20261.563 131 148 167 147 193 68 321 53 159 176 0 0
Totale 2.904