IRIS
PERUCCA, EMILIO
 Distribuzione geografica
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Continente #
NA - Nord America 13.345
AS - Asia 10.321
EU - Europa 7.636
SA - Sud America 1.244
AF - Africa 334
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 11
Totale 32.917
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Nazione #
US - Stati Uniti d'America 13.104
CN - Cina 5.154
SG - Singapore 2.294
IE - Irlanda 1.775
UA - Ucraina 1.382
HK - Hong Kong 1.121
BR - Brasile 939
DE - Germania 875
RU - Federazione Russa 797
VN - Vietnam 768
FI - Finlandia 619
FR - Francia 553
SE - Svezia 454
GB - Regno Unito 443
IT - Italia 388
IN - India 221
ZA - Sudafrica 147
CA - Canada 134
BD - Bangladesh 106
AR - Argentina 95
IQ - Iraq 88
JP - Giappone 85
TR - Turchia 69
MX - Messico 66
PL - Polonia 65
PK - Pakistan 58
NL - Olanda 56
ID - Indonesia 50
CO - Colombia 44
UZ - Uzbekistan 42
VE - Venezuela 41
SA - Arabia Saudita 40
EC - Ecuador 38
BE - Belgio 35
KE - Kenya 34
ES - Italia 33
PH - Filippine 31
CL - Cile 30
AT - Austria 29
MY - Malesia 28
EG - Egitto 27
TN - Tunisia 26
IL - Israele 23
MA - Marocco 22
AU - Australia 20
AE - Emirati Arabi Uniti 19
LT - Lituania 19
PE - Perù 19
PY - Paraguay 17
CZ - Repubblica Ceca 15
IR - Iran 15
MU - Mauritius 14
DZ - Algeria 13
JO - Giordania 13
SI - Slovenia 12
AZ - Azerbaigian 11
ET - Etiopia 10
SK - Slovacchia (Repubblica Slovacca) 10
EU - Europa 9
KR - Corea 9
NP - Nepal 9
PS - Palestinian Territory 9
UY - Uruguay 9
SN - Senegal 8
PA - Panama 7
RO - Romania 7
TH - Thailandia 7
BO - Bolivia 6
BY - Bielorussia 6
CH - Svizzera 6
DO - Repubblica Dominicana 6
GR - Grecia 6
KG - Kirghizistan 6
KZ - Kazakistan 6
NI - Nicaragua 6
TW - Taiwan 6
AL - Albania 5
AO - Angola 5
BG - Bulgaria 5
CR - Costa Rica 5
EE - Estonia 5
HN - Honduras 5
HR - Croazia 5
JM - Giamaica 5
MD - Moldavia 5
NO - Norvegia 5
LV - Lettonia 4
OM - Oman 4
QA - Qatar 4
TT - Trinidad e Tobago 4
AM - Armenia 3
BH - Bahrain 3
GA - Gabon 3
HU - Ungheria 3
LB - Libano 3
NZ - Nuova Zelanda 3
RS - Serbia 3
BJ - Benin 2
CI - Costa d'Avorio 2
CY - Cipro 2
Totale 32.857
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Città #
Chandler 1.861
Dublin 1.775
Jacksonville 1.661
Nanjing 1.224
Singapore 1.191
Hong Kong 1.098
Dallas 1.076
Ashburn 1.011
San Jose 998
Boardman 603
Beijing 556
Nanchang 472
Princeton 448
Lawrence 417
Wilmington 412
Lauterbourg 371
Shenyang 360
Changsha 354
Hebei 347
Los Angeles 304
Jiaxing 279
Ho Chi Minh City 278
Medford 269
Tianjin 218
Hangzhou 196
Hanoi 186
Buffalo 178
Ann Arbor 175
Redondo Beach 164
Helsinki 160
Woodbridge 126
Johannesburg 120
Moscow 114
Milan 105
Shanghai 101
New York 94
Fairfield 91
São Paulo 86
Saint Petersburg 85
Houston 78
Tokyo 75
Norwalk 71
Verona 71
Munich 67
Chicago 64
The Dalles 64
Toronto 61
Council Bluffs 54
Frankfurt am Main 54
Seattle 52
Cambridge 51
San Francisco 49
Orem 48
Santa Clara 48
Des Moines 44
Warsaw 43
Brooklyn 42
Columbus 41
Chennai 38
Da Nang 38
Guangzhou 38
Baghdad 36
Tashkent 36
Zhengzhou 35
Brussels 33
Kunming 31
London 31
Nuremberg 30
Pune 29
Pavia 28
Turku 28
Falls Church 27
Jinan 27
Nairobi 26
Falkenstein 25
Haiphong 25
Rio de Janeiro 25
Montreal 24
Dearborn 23
Dhaka 23
Atlanta 21
Charlotte 21
Amsterdam 20
Belo Horizonte 20
Curitiba 20
Mexico City 20
Taizhou 20
Denver 19
Phoenix 19
Piscataway 19
Manchester 18
Jeddah 17
Lahore 17
Mumbai 17
Tunis 17
Washington 17
Cairo 16
Caracas 16
Guarulhos 16
New Delhi 16
Totale 21.663
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Nome #
A simple and rapid HPLC-UV method for the determination of retigabine in human plasma 166
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. 161
A novel enantioselective microassay for the high-performance liquid chromatography determination of oxcarbazepine and its active metabolite monohydroxycarbazepine in human plasma 158
A multiparametric investigation of daytime sleepiness and psychomotor functions in epileptic patients treated with phenobarbital and sodium valproate: a comparative controlled study 157
A comparative study of free plasma choline levels following intramuscular administration of L-alpha-glycerylphosphorylcholine and citicoline in normal volunteers. 152
No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk—An analysis of Finnish health register and German health insurance data 152
Development and validation of an HPLC-UV detection assay for the determination of rufinamide in human plasma and saliva. 151
Induction of ethinylestradiol and levonorgestrel metabolism by oxcarbamazepine in healthy women 150
Alterazioni del campo visivo in soggetti epilettici in trattamento cronico con vigabatrin. 149
A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy. 144
A Double-Blind, Placebo-Controlled Study on the Effect of Vigabatrin on In Vivo Parameters of Hepatic Microsomal Enzyme Induction and on the Kinetics of Steroid Oral Contraceptives in Healthy Female Volunteers 142
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry 141
Changes in the disposition of oxcarbazepine and its metabolites during pregnancy and puerperium. 138
Six-year follow-up study on the efficacy and safety of vigabatrin in patients with epilepsy. 136
Low risk pragmatic trials do not always require participants' informed consent 136
A Prospective study on the effects of antiepileptic drugs on the human foetus: The European Registry initiative 134
A PHARMACOLOGICAL AND CLINICAL REVIEW ON TOPIRAMATE, A NEW ANTIEPILEPTIC DRUG, 128
Changes in lamotrigine pharmacokinetics during pregnancy and the puerperium. 127
Basal Ganglia Dysmorphism in Patients With Aicardi Syndrome 126
Stereoselective determination of vigabatrin enantiomers in human plasma by high performance liquid chromatography using UV detection. 125
Characteristics of a large population of patients with refractory epilepsy attending tertiary referral centers in Italy. on behalf of the SOPHIE Study Group. 125
ILAE Official Report: A practical clinical definition of epilepsy 124
A prospective study of direct medical costs in a large cohort of consecutively enrolled patients with refractory epilepsy in Italy 121
ILAE classification of the epilepsies: position paper of the ILAE Commission for Classification and Terminology 120
Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. 119
Clinical pharmacokinetics of fluvoxamine. 118
A functional polymorphism in the SCN1A gene does not influence antiepileptic drug responsiveness in Italian patients with focal epilepsy. 117
Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age 117
Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients. 116
Choreiform syndrome associated with fluoxetine treatment in a patient with deficient CYP2D6 activity. 115
Concentrations of L-dopa in plasma and plasma ultrafiltrates. 114
Determinants of health-related quality of life in pharmacoresistant epilepsy: results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments.SOPHIE Study Group. 114
Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia (Oxford) 51, 1069-1077, 2010 114
Increased Apparent Oral Clearance of Valproic Acid during Intake of Combined Contraceptive Steroids in Women with Epilepsy 113
Omeprazole Does Not Enhance the Metabolism of Phenacetin, a Marker of CYP1A2 Activity, in Healthy Volunteers 113
Plasma concentrations of the enantiomers of fluoxetine and norfluoxetine sources of variability and preliminary observations on relations with clinical response. 112
Effect of active and passive cigarette smoking on CYP1A2-mediated phenacetin disposition in Chinese subjects. 112
Determination of Perampanel in Dried Plasma Spots: Applicability to Therapeutic Drug Monitoring 112
Measurement of seizure freedom in adjunctive therapy studies in refractory partial epilepsy: the levetiracetam experience 111
2017 International League Against Epilepsy classifications of seizures and epilepsy are steps in the right direction 111
A web-based algorithm to rapidly classify seizures for the purpose of drug selection 110
Novel Medications for Epilepsy 109
Effects of phenytoin on the in vivo kinetics of thiamine and its phosphoesters in rat nervous tissues 108
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. Commentary. 108
Bioequivalence and switchability of generic antiseizure medications (ASMs): A re-appraisal based on analysis of generic ASM products approved in Europe 108
Antiepileptic drug use and epileptic seizures in nursing home residents in the Province of Pavia, Italy: A reappraisal 12 years after a first survey 106
Development and validation of an HPLC-UV assay for the therapeutic monitoring of the new antiepileptic drug perampanel in human plasma 106
The new antiepileptic drugs: Pharmacological and clinical aspects. 105
Daytime sleepiness in healthy university students: A multiparametric study 105
A comparative study of the effect of carbamazepine and valproic acid on the pharmacokinetics and metabolic profile of topiramate at steady state in patients with epilepsy 105
Influence of aging on serum phenytoin concentrations: A pharmacokinetic analysis based on therapeutic drug monitoring data. 104
Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). 104
Valproic acid after five decades of use in epilepsy: Time to reconsider the indications of a time-honoured drug 104
THE INFLUENCE OF OLD AGE AND ENZYME INDUCING COMEDICATION ON THE PHARMACOKINETICS OF VALPROIC ACID AT STEADY STATE: A CASE-MATCHED EVALUATION BASED ON THERAPEUTIC DRUG MONITORING DATA. 104
Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs. 104
Pharmacokinetic variability of new antiepileptic drugs at different ages. 103
Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation 103
Comparative pharmacokinetics and pharmacodynamics of eterobarbital and phenobarbital in normal volunteers. 103
Inhibition of diazepam metabolism by fluvoxamine: a pharmacokinetic study in normal volunteers. 103
ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. 102
Enantioselective effects of levodropropizine and dropropizine on psychomotor functions in normal volunteers: a placebo-controlled, double-blind comparative study. 102
DIFFERENTIAL-EFFECTS OF VALPROIC ACID AND ENZYME-INDUCING ANTICONVULSANTS ON NIMODIPINE PHARMACOKINETICS IN EPILEPTIC PATIENTS 102
Add-on lamotrigine treatment in children and young adults with severe partial epilepsy: a open, prospective, long-term study 101
Effect of ketoconazole on the pharmacokinetics of imipramine and desipramine in healthy subjects 100
Epilessia nell'anziano:dati dai registri di un centro neurologico. 99
Therapeutic strategies against epilepsy in Mediterranean countries: a report from an international collaborative survey. 99
Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine. 99
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias. 98
Can drug resistance in epilepsy be minimized? Challenging commonly held beliefs. 98
A pragmatic algorithm to select appropriate antiseizure medications in patients with epilepsy 98
Withdrawing antiepileptic drugs in seizure-free patients: what are the cognitive benefits? 97
Patterns of prescription of antiepileptic drugs in patients with refractory epilepsy at tertiary referral centres in Italy. 97
Overtreatment in epilepsy: adverse consequences and mechanisms. 96
Erratum The long-term effect of vagus nerve stimulation on quality of life in patients with pharmacoresistant focal epilepsy: The PuLsE (Open Prospective Randomized Long-term Effectiveness) trial (Epilepsia (2014) 55 (893-900) 96
CYP2D6-related oxidation polymorphism in Italy 96
The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction 95
Vigabatrin and epilepsy. Lessons learned. 95
Farmacocinetica delle benzodiazepine. 95
Does screening for adverse effects improve health outcomes in epilepsy? A randomized trial 95
Pharmacokinetics of a valpromide isomer, valnoctamide, in healthy subjects 94
What clinical trial designs have been used to test antiepileptic drugs and do we need to change them? 94
When clinical trials make history: Demonstrating efficacy of new antiepileptic drugs as monotherapy. 94
Topiramate pharmacokinetics in children and adults with epilepsy: A case-matched comparison based on therapeutic drug monitoring data. 94
The remarkable story of valproic acid 94
A new classification is born 94
Daytime sleepiness in epileptic patients on long-term monotherapy: MSLT, clinical and psychometric assessment 94
A summary of data presented at the XIV conference on new antiepileptic drug and devices (EILAT XIV) 94
Cost minimization analysis of antiepileptic drugs in newly diagnosed epilepsy in 12 European countries 93
Plasma gabapentin concentrations in children with epilepsy: Influence of age, relationship with dosage, and preliminary observations on correlation with clinical response 93
Major birth defects after exposure to newer-generation antiepileptic drugs. 93
Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy, and comorbid depressive-like behavior 93
Harnessing the clinical potential of antiepileptic drug therapy: dosage optimisation 92
Revisiting phenobarbital for epilepsy. 92
Role of valproate across the ages. Treatment of epilepsy in the elderly 92
Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: A clinically relevant pharmacokinetic drug interaction 92
Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy 92
Relationship between adverse effects of antiepileptic drugs, number of coprescribed drugs, and drug load in a large cohort of consecutive patients with drug-refractory epilepsy 92
Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes 92
The management of refractory idiopathic epilepsies 91
The Influence of Dosage, Age, and Comedication on Steady State Plasma Lamotrigine Concentrations in Epileptic Children 91
Totale 11.103
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Categoria #
all - tutte 139.687
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 139.687
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021765 0 0 0 0 0 0 0 0 0 351 316 98
2021/20221.632 31 5 64 21 20 36 27 101 100 18 275 934
2022/20235.273 641 314 37 471 518 593 0 355 2.110 25 136 73
2023/20241.577 222 281 58 137 170 413 30 107 11 45 60 43
2024/20254.438 141 480 126 178 74 186 145 366 978 166 477 1.121
2025/202610.286 786 1.085 1.420 1.059 1.177 460 2.312 467 873 647 0 0
Totale 33.296