Distribuzione geografica
Continente #
NA - Nord America 1857
EU - Europa 1342
AS - Asia 1179
Continente sconosciuto - Info sul continente non disponibili 8
AF - Africa 4
Totale 4390
Nazione #
US - Stati Uniti d'America 1828
CN - Cina 1163
UA - Ucraina 418
FI - Finlandia 199
DE - Germania 193
IT - Italia 143
SE - Svezia 140
GB - Regno Unito 125
FR - Francia 73
BE - Belgio 41
CA - Canada 29
EU - Europa 6
IR - Iran 6
IN - India 4
RU - Federazione Russa 4
TR - Turchia 4
MA - Marocco 3
A2 - ???statistics.table.value.countryCode.A2??? 2
NL - Olanda 2
AT - Austria 1
HK - Hong Kong 1
KR - Corea 1
LV - Lettonia 1
MU - Mauritius 1
PT - Portogallo 1
RO - Romania 1
Totale 4390
Città #
Chandler 547
Jacksonville 478
Nanjing 372
Ann Arbor 195
Beijing 162
Nanchang 125
Hebei 99
Princeton 97
Shenyang 94
Lawrence 91
Medford 84
Wilmington 81
Changsha 79
Jiaxing 76
Boardman 60
Tianjin 57
Hangzhou 56
Brussels 41
Milan 38
Woodbridge 38
Toronto 29
Pavia 23
Verona 19
Helsinki 17
Mountain View 17
Norwalk 16
Des Moines 14
Auburn Hills 12
Dearborn 8
Ningbo 8
Kunming 6
Redwood City 6
Fairfield 5
Houston 5
Zhengzhou 5
Berlin 4
Pioltello 4
Guangzhou 3
Jinan 3
Los Angeles 3
San Francisco 3
Andover 2
Changchun 2
Fabbrico 2
Haikou 2
Lanzhou 2
Rome 2
Taizhou 2
Wetter 2
Abbiategrasso 1
Ancona 1
Arcore 1
Ashburn 1
Asso 1
Borås 1
Casoria 1
Cremona 1
Delhi 1
Fuzhou 1
Gostar 1
Hefei 1
Hunedoara 1
Jaipur 1
Jinhua 1
Kemerovo 1
Kiev 1
Lamézia 1
Leawood 1
Limoges 1
Lodi 1
London 1
Maranello 1
Meda 1
Monmouth Junction 1
Montegiordano 1
Novokuznetsk 1
Orange 1
Palombara Sabina 1
Pioner 1
Ponte De Sor 1
Redmond 1
Selargius 1
Seoul 1
Shanghai 1
Stornara 1
Tomsk 1
Zanjan 1
Élancourt 1
Totale 3135
Nome #
Estrazione di flavonoidi da Crataegus monogyna Jacq. mediante microonde (MASE), un'alternativa alla macerazione, all'estrazione con Soxhlet e con ultrasuoni (USAE). 96
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 79
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 73
Disegno razionale e sintesi di ligandi selettivi per il sottotipo recettoriale sigma1 73
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 71
Preparation and Configuration of Racemic and Optically Active Analgesic Cycloaminoalkiynaphthalenes 70
SAR Evaluation of Chiral Naphthylorfines with Antinociceptive Activity 70
Sintesi parallela in soluzione di scaffolds olefinici per la preparazione di nuovi ligandi sigma 69
Disegno razionale, sintesi e valutazione biologica di nuovi ligandi ad elevata affinità per i recettori sigma 1 a struttura fenilalchenil- e fenilalchil- amminica 67
Preparazione mediante reattivi supportati e riscaldamento a microonde di esteri alpha-beta-insaturi, intermedi chiave per la sintesi di nuovi ligandi sigma 67
Microwave assisted synthesis of chiral pyrrolines with biological activity 66
Concorsi per Farmacie-Guida alla risoluzione dei quiz 64
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 64
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 63
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 63
Novel sigma ligands: design, preparation and biological evaluation 61
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 60
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 60
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 59
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 58
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics 57
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 56
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 56
Derivati indolilalchilaminici. Approccio razionale alla progettazione di nuovi ligandi sigma 54
Synthesis and SAR of Novel Sigma1 Selective Ligands 54
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 53
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 53
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 53
Chiral recognition of alkyl 2-aryloxypropionates by HPLC 53
Progettazione e Sintesi di nuovi Ligandi Sigma 52
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 52
Benzooxazol-2-one and benzothiazol-2-one derivatives as possibile sigma ligands 51
Design, synthesis and pharmacological activity of new antinociceptive agents 50
Pharmacophore-based drug design of novel selective sigma1 ligands 49
Risoluzione di ligandi selettivi sigma1 a struttura alchilamminoalchilarilica mediante HPLC chirale e studio configurazionale 49
Rational Approach to the Design of Selective Sigma 1 Ligands 49
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 49
Synthesis and pharmacological evaluation of opiod-like chiral naphthylaminoalcohols 48
Efficient Microwave and Phosphane-free Synthesis of Trisubstituted Olefins via Heck Coupling 47
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 47
Concorsi per farmacie. Guida alla risoluzione dei quiz. 47
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 47
Stereospecific effects of benzo[d]isothiazolyloxypropanolamine derivatives at beta-adrenoceptors: synthesis, chiral resolution and biological activity in vitro 46
Simple (R) chirally induced syntheses of (+)-(2E,4E,8Z)-ethyl 6-tetrahydropyranyloxytetradeca-2,4,8-trienoate, a versatile prosynthon C-14 for LTB4 46
null 46
Chiral arylpyrrolidinols: preparation and biological profile 45
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 45
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 45
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 45
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 45
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 45
Chiral resolution and absolute configuration of the enantiomers of 5-acetyl-2-methyl-4-methylsulfinyl-6-phenyl-3(2H)-pyridazinone and evaluation of their platelet aggregationinhibitory activity 45
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 44
Novel Racemic and Optically Active Dialkylaminoalkylnaphthalenes with Antinociceptive Activity. 43
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 43
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 42
Substituted Benzo[d]oxazol-2(3H)-one Derivatives with Preference for the sigma1 Binding Site 42
Substituted benzo[d]oxazol-2-(3H)-one derivatives as possibile sigma ligands 42
Metodi cromatografici-Cromatografia ad alta prestazione 41
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 41
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 41
Optical resolution of aryloxypropionic acids and their esters by HPLC on cellulosetris-(3,5-dimethyl-triphenyl)-carbamate derivative 40
Synthesis and antinociceptive activity of Pyrrolidinylnaphthalenes 40
Preparation of (+)- and (-)-1,2-dimethyl-3-pyrrolidone and stability studies 39
Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site 38
Studies on the enantiomers of RC-33, promising neuroprotective agents acting as sigma1 receptor agonists. Isolation, configurational assignment and biological profile 38
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity. 37
Preparation and configuration of racemic and optically active analgesicdialkylaminoalkyl-naphthalenes 37
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 37
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties 37
Substituted benzylaminoalkylindoles with preference for the sigma2 binding site 36
Preparation of arene carboxylic acids via a polymer-supported Kröhnke reaction 36
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 36
Efficient Microwave and Phosphane-Free Synthesis of Trisubstituted Olefins via Heck Coupling 35
Stereoselective hydrolysis by esterase: a strategy for resolving 2-(R,R’-phenoxy)propionyl ester racemates 33
Phytochemical fingerprint and anti-inflammatory properties of crude extract and naringenin from Amygdalus lycioides Spach 33
Synthesis of Pyrrolinylnaphthalenes and evaluation of their antinociceptive activity 33
Basic Isomerisation of some methyl 4-hydroxy-4-alkylbut-2-enoates 33
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 33
Chiral resolution, configurational study and pharmacological profile of 2-phenoxypropionic acids 32
Diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols with analgesic activity 29
Stereoselective Hydrolysis by Esterase: A Strategy for Resolving 2-(R, R′-Phenoxy)propionyl Ester Racemates. 27
Microwave- and Polymer-Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Wittig Reaction. 26
Chiral resolution of methyl 2-aryloxypropionates by biocatalytic stereospecifichydrolysis 26
Enantiomers of 2-[(Acylamino)ethyl]-1,4-benzodiazepines, Potent Ligands of k-Opioid Receptor: Chiral Chromatographic Resolution, Configurational Assignment, and Biological Activity. 24
Design, synthesis and SAR analysis of novel selective sigma1 ligands 8
Totale 4414
Categoria #
all - tutte 8091
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8091

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018127 0000 00 015 510043
2018/2019389 1141274 95 9810 8713813
2019/20201516 382569784 1184 2291 101511014
2020/2021759 92762286 8105 1495 2511310122
2021/2022489 1013319 1022 1536 241758244
2022/2023807 14615119128 175183 50 0000
Totale 4414