IRIS
ROSSI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 5.356
AS - Asia 4.016
EU - Europa 3.638
SA - Sud America 527
AF - Africa 63
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 1
Totale 13.607
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Nazione #
US - Stati Uniti d'America 5.205
CN - Cina 2.268
IE - Irlanda 929
SG - Singapore 820
RU - Federazione Russa 485
HK - Hong Kong 432
BR - Brasile 426
DE - Germania 416
UA - Ucraina 401
IT - Italia 371
FI - Finlandia 361
GB - Regno Unito 198
VN - Vietnam 159
SE - Svezia 148
FR - Francia 109
IN - India 103
CA - Canada 90
JP - Giappone 59
BE - Belgio 46
AR - Argentina 44
MX - Messico 40
ZA - Sudafrica 32
ES - Italia 31
PL - Polonia 29
BD - Bangladesh 28
IQ - Iraq 28
LT - Lituania 23
NL - Olanda 20
ID - Indonesia 18
AT - Austria 16
CZ - Repubblica Ceca 16
TR - Turchia 14
EC - Ecuador 12
CO - Colombia 11
VE - Venezuela 10
IR - Iran 8
CH - Svizzera 7
CL - Cile 7
KR - Corea 7
UZ - Uzbekistan 7
AE - Emirati Arabi Uniti 6
JO - Giordania 6
PE - Perù 6
PK - Pakistan 6
UY - Uruguay 6
EU - Europa 5
IL - Israele 5
KE - Kenya 5
MA - Marocco 5
PH - Filippine 5
PY - Paraguay 5
TT - Trinidad e Tobago 5
AM - Armenia 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
EG - Egitto 4
KZ - Kazakistan 4
PA - Panama 4
RO - Romania 4
AZ - Azerbaigian 3
BG - Bulgaria 3
DZ - Algeria 3
GR - Grecia 3
HU - Ungheria 3
JM - Giamaica 3
KG - Kirghizistan 3
LK - Sri Lanka 3
MU - Mauritius 3
PT - Portogallo 3
AL - Albania 2
CI - Costa d'Avorio 2
CR - Costa Rica 2
CU - Cuba 2
EE - Estonia 2
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LV - Lettonia 2
NP - Nepal 2
SA - Arabia Saudita 2
SN - Senegal 2
TH - Thailandia 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AO - Angola 1
AU - Australia 1
BH - Bahrain 1
BJ - Benin 1
GA - Gabon 1
GT - Guatemala 1
HR - Croazia 1
IS - Islanda 1
KH - Cambogia 1
ME - Montenegro 1
ML - Mali 1
MN - Mongolia 1
MY - Malesia 1
NO - Norvegia 1
OM - Oman 1
PS - Palestinian Territory 1
QA - Qatar 1
Totale 13.601
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Città #
Dublin 926
Chandler 882
Beijing 535
Dallas 505
Jacksonville 504
Nanjing 461
Ashburn 433
Singapore 427
Hong Kong 426
Boardman 237
Nanchang 180
Los Angeles 172
Ann Arbor 160
Princeton 146
Lawrence 140
New York 136
Munich 133
Hebei 129
Helsinki 125
Shanghai 122
Pavia 118
Wilmington 118
Shenyang 117
Medford 113
Changsha 106
Jiaxing 91
Moscow 89
Tianjin 77
Hangzhou 72
Ho Chi Minh City 72
Redondo Beach 63
Buffalo 55
Milan 54
Pune 54
Tokyo 53
São Paulo 43
Brussels 41
Toronto 40
Woodbridge 37
Seattle 36
The Dalles 35
Piscataway 34
Turku 34
Santa Clara 29
Stockholm 29
Johannesburg 27
Chicago 26
Denver 26
Warsaw 25
Chennai 24
Hanoi 24
Montreal 23
Norwalk 23
Dearborn 22
London 22
Orem 22
Columbus 19
Phoenix 19
Fairfield 18
Houston 17
Mexico City 17
Poplar 17
Brooklyn 16
Florence 16
Boston 15
Zhengzhou 15
Manchester 14
Amsterdam 13
Atlanta 13
San Francisco 13
Curitiba 12
Frankfurt am Main 12
Nuremberg 12
Rio de Janeiro 12
Rome 12
Verona 12
Guangzhou 11
Washington 11
Haiphong 10
Jinan 10
Couilly-pont-aux-dames 9
Da Nang 9
Des Moines 9
Salvador 9
Biên Hòa 8
Brasília 8
Newark 8
Ottawa 8
Redwood City 8
Vienna 8
Auburn Hills 7
Baghdad 7
Belo Horizonte 7
Dhaka 7
Erbil 7
Miami 7
Ningbo 7
Querétaro 7
Tashkent 7
Amman 6
Totale 9.142
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Nome #
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 146
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 139
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 139
Approaches for multi-gram scale isolation of enantiomers for drug discovery 135
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 133
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 133
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 133
Formulation of microspheres containing Crataegus monogyna extract in feed design 131
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 127
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 125
Progettazione e Sintesi di nuovi Ligandi Sigma 124
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 124
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 124
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 123
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 123
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 123
Novel sigma ligands: design, preparation and biological evaluation 121
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 121
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 120
Sigma receptor modulators: a patent review. 118
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 117
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 117
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 116
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 116
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 115
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 115
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 114
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 114
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 113
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 113
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 111
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 111
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 110
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 110
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 110
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 110
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 109
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 109
Design, synthesis and pharmacological activity of new antinociceptive agents 108
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 107
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 107
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 107
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 106
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 106
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 105
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 105
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 104
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 104
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 103
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 103
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 103
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 103
Chiral arylpyrrolidinols: preparation and biological profile 102
MW-assisted Fischer synthesis of new indolylimidazole and indolyltriazole derivatives 102
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 102
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 102
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 102
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 101
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 99
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 99
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 98
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 98
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 97
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 96
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 96
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 94
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 94
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 94
Are sigma receptor modulators a weapon against multiple sclerosis disease? 94
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 94
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 94
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity 92
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 90
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 90
The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material 90
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment 90
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 88
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 88
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 87
Discovery of Small Peptides Derived from Embryonic Lethal Abnormal Vision Proteins Structure Showing RNA-Stabilizing Properties 87
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy 87
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 86
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies 86
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 86
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 86
New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative 86
PKC in regenerative therapy: New insights for old targets 85
Enantioselective Modulatory Effects of Naringenin Enantiomers on the Expression Levels of miR‐17‐3p Involved in Endogenous Antioxidant Defenses 85
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 84
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 84
Phytochemical and biological profile of Eremurus persicus Boiss root extract: isolation of the main phytocomponents. 83
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 81
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells. 81
3D pharmacophore model of sigma1 binding site based on a series of subtitued benzo[d]oxazol-2(3H)-one derivatives. 81
PEG 400/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds 81
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach 81
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 79
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 78
Synthesis and biological evaluation of small peptides able to mimic ELAV RNA-binding proteins: new perspective in neurodegenerative diseases treatment 77
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 77
Totale 10.377
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Categoria #
all - tutte 57.198
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.198
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021535 0 0 0 0 0 119 21 131 33 119 90 22
2021/2022704 10 5 29 12 9 21 13 52 40 30 93 390
2022/20232.456 234 222 26 173 238 249 0 135 1.075 15 60 29
2023/20241.039 117 166 24 48 97 261 65 72 5 40 79 65
2024/20252.656 43 190 73 80 132 185 138 148 663 100 311 593
2025/20263.348 487 326 769 680 845 241 0 0 0 0 0 0
Totale 13.843