IRIS
ROSSI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 3.589
EU - Europa 2.614
AS - Asia 1.925
SA - Sud America 11
Continente sconosciuto - Info sul continente non disponibili 6
AF - Africa 3
OC - Oceania 1
Totale 8.149
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Nazione #
US - Stati Uniti d'America 3.557
CN - Cina 1.651
IE - Irlanda 929
UA - Ucraina 386
FI - Finlandia 321
IT - Italia 297
DE - Germania 289
SG - Singapore 176
SE - Svezia 118
GB - Regno Unito 105
FR - Francia 95
IN - India 60
BE - Belgio 42
CA - Canada 27
JP - Giappone 12
RU - Federazione Russa 10
CZ - Repubblica Ceca 7
IQ - Iraq 6
IR - Iran 6
EU - Europa 5
NL - Olanda 4
BR - Brasile 3
MU - Mauritius 3
CH - Svizzera 2
CL - Cile 2
CO - Colombia 2
CU - Cuba 2
HK - Hong Kong 2
ID - Indonesia 2
LT - Lituania 2
PK - Pakistan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AM - Armenia 1
AR - Argentina 1
AU - Australia 1
BD - Bangladesh 1
BG - Bulgaria 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
GR - Grecia 1
HU - Ungheria 1
KR - Corea 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MX - Messico 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PL - Polonia 1
PT - Portogallo 1
PY - Paraguay 1
RO - Romania 1
TR - Turchia 1
Totale 8.149
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Città #
Dublin 926
Chandler 882
Jacksonville 503
Nanjing 459
Beijing 243
Ashburn 238
Boardman 238
Nanchang 180
Ann Arbor 160
Princeton 146
Lawrence 140
Hebei 129
Singapore 122
Helsinki 120
Wilmington 118
Shenyang 115
Shanghai 114
Medford 113
Pavia 112
Changsha 99
Jiaxing 91
New York 78
Tianjin 74
Hangzhou 69
Pune 53
Munich 44
Brussels 37
Woodbridge 37
Milan 35
Seattle 35
Piscataway 34
Los Angeles 33
Toronto 24
Norwalk 23
Dearborn 22
Fairfield 18
Tokyo 12
Verona 12
Dallas 11
Washington 10
Couilly-pont-aux-dames 9
Des Moines 9
Jinan 8
Redwood City 8
Zhengzhou 8
Auburn Hills 7
Chicago 7
Ningbo 7
Brno 6
Guangzhou 6
Santa Clara 6
Trezzano Rosa 6
Kunming 5
Rome 5
Sulaymaniyah 5
Aachen 4
Caleppio 4
Changchun 4
Houston 4
Padova 4
Tappahannock 4
Wetter 4
Berlin 3
Bresso 3
Falkenstein 3
Inzago 3
Moscow 3
Orange 3
Paris 3
Rockville 3
Scottsdale 3
Siena 3
Torino 3
Atlanta 2
Barranquilla 2
Borås 2
Casorate Primo 2
Cernusco sul Naviglio 2
Cittadella 2
Fabbrico 2
Fayetteville 2
Florence 2
Fuzhou 2
Haikou 2
Havana 2
Modena 2
Nagold 2
Nave 2
Newark 2
Novokuznetsk 2
Pioltello 2
Purwokerto 2
Redmond 2
Reggio Emilia 2
Rozzano 2
Segrate 2
Sialkot 2
Turin 2
Abbiategrasso 1
Amsterdam 1
Totale 6.124
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Nome #
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 97
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 96
Formulation of microspheres containing Crataegus monogyna extract in feed design 96
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 90
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 89
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 87
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 86
Progettazione e Sintesi di nuovi Ligandi Sigma 85
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 83
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 81
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 80
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 80
Novel sigma ligands: design, preparation and biological evaluation 79
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 79
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 79
Sigma receptor modulators: a patent review. 79
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 78
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 78
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 77
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 76
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 75
Design, synthesis and pharmacological activity of new antinociceptive agents 75
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 75
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 74
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 74
Approaches for multi-gram scale isolation of enantiomers for drug discovery 74
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 73
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 73
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 73
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 73
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 72
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 72
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 72
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 71
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 71
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 71
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 70
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 70
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 69
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 68
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 68
MW-assisted Fischer synthesis of new indolylimidazole and indolyltriazole derivatives 68
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 68
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 68
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 67
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 67
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 66
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 66
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 66
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 66
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 65
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 65
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 65
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 64
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 64
Chiral arylpyrrolidinols: preparation and biological profile 63
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 63
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 63
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 62
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 62
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 61
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 61
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells. 61
Synthesis and biological evaluation of small peptides able to mimic ELAV RNA-binding proteins: new perspective in neurodegenerative diseases treatment 60
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 59
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 58
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 58
Substituted Benzo[d]oxazol-2(3H)-one Derivatives with Preference for the sigma1 Binding Site 57
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 57
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 57
PREPARATIVE ENANTIOSELECTIVE HPLC OF RACEMIC NARINGENIN AND BIOLOGICAL PROFILE INVESTIGATION OF PURE ENANTIOMERS 56
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 56
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 55
Phytochemical and biological profile of Eremurus persicus Boiss root extract: isolation of the main phytocomponents. 55
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 55
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity 55
Optimal graph-based and Simplified Molecular Input Line Entry System-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as sigma1 receptor ligands 55
Use of arylalkanolamines as sigma-1 receptor antagonists 55
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 55
Stereospecific effects of benzo[d]isothiazolyloxypropanolamine derivatives at beta-adrenoceptors: synthesis, chiral resolution and biological activity in vitro 54
New prospective in the design and in the synthesis of new sigma ligands: computational approach and classic way 54
Quick development of an analytical enantioselective high performance liquid chromatography separation and preparative scale-up for the flavonoid Naringenin 54
Novel Racemic and Optically Active Dialkylaminoalkylnaphthalenes with Antinociceptive Activity. 54
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 54
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies 54
The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material 54
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 54
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy 54
Northern Italy Plant Extracts with ROS-scavenging activity: microsphere formulation in feed design. 53
Identification and quantification of α-dicarbonyl compounds in balsamic and traditional balsamic vinegars and their cytotoxicity against human cells 53
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084,in a mouse model of motor neuron disease not linked to SOD1 mutation 52
Are sigma receptor modulators a weapon against multiple sclerosis disease? 52
Drug discovery e chiralità: il contributo del MedChemLab-Unipv 51
Studies on the enantiomers of RC-33, promising neuroprotective agents acting as sigma1 receptor agonists. Isolation, configurational assignment and biological profile 51
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 51
3D pharmacophore model of sigma1 binding site based on a series of subtitued benzo[d]oxazol-2(3H)-one derivatives. 51
“Fit-for-purpose” development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel sigma1 receptor agonist. 51
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 49
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 49
Sigma receptors as endoplasmic reticulum stress "gatekeepers" and their modulators as emerging new weapons in the fight against cancer 49
Totale 6.610
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Categoria #
all - tutte 34.232
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.232
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020553 0 0 0 0 15 84 17 100 30 174 127 6
2020/2021805 88 69 15 86 12 119 21 131 33 119 90 22
2021/2022704 10 5 29 12 9 21 13 52 40 30 93 390
2022/20232.456 234 222 26 173 238 249 0 135 1.075 15 60 29
2023/20241.043 117 166 24 48 97 261 65 72 5 40 79 69
2024/2025516 44 191 73 80 128 0 0 0 0 0 0 0
Totale 8.359