IRIS
ROSSI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 6.834
AS - Asia 4.863
EU - Europa 4.020
SA - Sud America 708
Continente sconosciuto - Info sul continente non disponibili 246
AF - Africa 173
OC - Oceania 1
Totale 16.845
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Nazione #
US - Stati Uniti d'America 6.615
CN - Cina 2.398
SG - Singapore 998
IE - Irlanda 933
HK - Hong Kong 515
BR - Brasile 505
RU - Federazione Russa 491
IT - Italia 449
DE - Germania 443
UA - Ucraina 405
VN - Vietnam 390
FI - Finlandia 371
FR - Francia 277
GB - Regno Unito 234
IN - India 151
SE - Svezia 148
CA - Canada 120
ZA - Sudafrica 101
BD - Bangladesh 80
AR - Argentina 69
JP - Giappone 66
MX - Messico 55
BE - Belgio 47
IQ - Iraq 46
ES - Italia 39
PL - Polonia 33
CO - Colombia 32
NL - Olanda 31
VE - Venezuela 31
ID - Indonesia 26
LT - Lituania 25
EC - Ecuador 23
PK - Pakistan 23
TR - Turchia 23
CZ - Repubblica Ceca 18
AT - Austria 17
CL - Cile 15
UZ - Uzbekistan 15
CR - Costa Rica 11
MA - Marocco 11
MY - Malesia 11
PH - Filippine 11
CH - Svizzera 10
KE - Kenya 10
PE - Perù 10
SA - Arabia Saudita 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
PY - Paraguay 9
IR - Iran 8
JO - Giordania 8
KR - Corea 8
AZ - Azerbaigian 7
JM - Giamaica 7
UY - Uruguay 7
AL - Albania 6
BG - Bulgaria 6
EG - Egitto 6
KG - Kirghizistan 6
PA - Panama 6
PT - Portogallo 6
TT - Trinidad e Tobago 6
AM - Armenia 5
DO - Repubblica Dominicana 5
DZ - Algeria 5
EU - Europa 5
IL - Israele 5
KH - Cambogia 5
KZ - Kazakistan 5
NP - Nepal 5
RO - Romania 5
BO - Bolivia 4
CI - Costa d'Avorio 4
DK - Danimarca 4
LK - Sri Lanka 4
MU - Mauritius 4
PS - Palestinian Territory 4
RS - Serbia 4
SN - Senegal 4
GR - Grecia 3
GY - Guiana 3
HU - Ungheria 3
LB - Libano 3
LV - Lettonia 3
NI - Nicaragua 3
PR - Porto Rico 3
TH - Thailandia 3
AO - Angola 2
CU - Cuba 2
EE - Estonia 2
ET - Etiopia 2
GA - Gabon 2
HR - Croazia 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
MG - Madagascar 2
ML - Mali 2
MN - Mongolia 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
Totale 16.584
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Città #
Dublin 928
Chandler 882
San Jose 597
Ashburn 588
Singapore 552
Beijing 549
Dallas 513
Jacksonville 505
Hong Kong 501
Nanjing 461
Council Bluffs 245
Boardman 238
Los Angeles 202
Nanchang 180
Ann Arbor 160
Ho Chi Minh City 150
Lauterbourg 147
New York 146
Princeton 146
Lawrence 140
Helsinki 134
Munich 133
Hebei 129
Pavia 124
Shanghai 123
Wilmington 118
Shenyang 117
Medford 113
Changsha 107
Johannesburg 92
Jiaxing 91
Moscow 90
Hanoi 78
Santa Clara 78
Tianjin 77
Hangzhou 72
Redondo Beach 63
Buffalo 62
Milan 59
Tokyo 59
Pune 54
São Paulo 53
Orem 48
Toronto 47
Brussels 42
Woodbridge 39
Chennai 37
Piscataway 37
Seattle 37
The Dalles 35
Turku 34
Chicago 31
London 31
Columbus 30
Montreal 30
Denver 29
Frankfurt am Main 29
Stockholm 29
Warsaw 28
Norwalk 23
Da Nang 22
Dearborn 22
Manchester 22
Mexico City 22
Phoenix 22
Amsterdam 19
Houston 19
Rome 19
Atlanta 18
Fairfield 18
Brooklyn 17
Poplar 17
Florence 16
Nuremberg 16
Boston 15
San Francisco 15
Tashkent 15
Verona 15
Zhengzhou 15
Haiphong 14
Naples 14
Baghdad 13
Brasília 13
Curitiba 13
Newark 12
Rio de Janeiro 12
Basingstoke 11
Guangzhou 11
Washington 11
Jinan 10
New Delhi 10
Salvador 10
Biên Hòa 9
Caracas 9
Couilly-pont-aux-dames 9
Des Moines 9
Dhaka 9
Nairobi 9
Vienna 9
Erbil 8
Totale 11.041
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Nome #
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 173
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 165
Formulation of microspheres containing Crataegus monogyna extract in feed design 155
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 154
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 150
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 150
Approaches for multi-gram scale isolation of enantiomers for drug discovery 149
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 148
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 148
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 148
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 148
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 144
Progettazione e Sintesi di nuovi Ligandi Sigma 143
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 143
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 143
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 142
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 141
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 141
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 140
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 138
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 138
Novel sigma ligands: design, preparation and biological evaluation 137
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 137
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 137
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 135
Sigma receptor modulators: a patent review. 135
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 134
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 133
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 133
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 132
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 132
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 131
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 131
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 131
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 131
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 130
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 130
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 130
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 128
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 128
Design, synthesis and pharmacological activity of new antinociceptive agents 127
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 127
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 127
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 127
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 127
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 126
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 125
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 124
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 122
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 121
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 121
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 120
Chiral arylpyrrolidinols: preparation and biological profile 119
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 119
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 118
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 118
Are sigma receptor modulators a weapon against multiple sclerosis disease? 118
MW-assisted Fischer synthesis of new indolylimidazole and indolyltriazole derivatives 117
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 117
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 117
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 116
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 116
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 116
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 115
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 115
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 115
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 114
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 113
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 113
The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material 113
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 113
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 112
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 110
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies 110
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 109
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment 109
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy 108
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 107
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 107
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 106
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity 105
Discovery of Small Peptides Derived from Embryonic Lethal Abnormal Vision Proteins Structure Showing RNA-Stabilizing Properties 104
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 103
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 103
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach 103
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 103
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 102
PEG 400/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds 102
Enantioselective Modulatory Effects of Naringenin Enantiomers on the Expression Levels of miR‐17‐3p Involved in Endogenous Antioxidant Defenses 102
New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative 101
PKC in regenerative therapy: New insights for old targets 99
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 99
CHAPTER 12: Sigma Receptors as New Target for Multiple Sclerosis 99
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 98
3D pharmacophore model of sigma1 binding site based on a series of subtitued benzo[d]oxazol-2(3H)-one derivatives. 98
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents 97
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 97
Phytochemical and biological profile of Eremurus persicus Boiss root extract: isolation of the main phytocomponents. 97
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 97
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 96
Totale 12.295
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Categoria #
all - tutte 68.904
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.904
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022689 0 0 29 12 9 21 13 52 40 30 93 390
2022/20232.456 234 222 26 173 238 249 0 135 1.075 15 60 29
2023/20241.039 117 166 24 48 97 261 65 72 5 40 79 65
2024/20252.656 43 190 73 80 132 185 138 148 663 100 311 593
2025/20265.921 487 326 769 680 845 249 1.048 251 554 433 144 135
2026/2027429 92 293 44 0 0 0 0 0 0 0 0 0
Totale 16.845