IRIS
ROSSI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 6.202
AS - Asia 4.792
EU - Europa 3.964
SA - Sud America 686
AF - Africa 172
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 1
Totale 15.824
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Nazione #
US - Stati Uniti d'America 6.023
CN - Cina 2.371
SG - Singapore 984
IE - Irlanda 931
HK - Hong Kong 508
BR - Brasile 496
RU - Federazione Russa 491
DE - Germania 442
UA - Ucraina 405
IT - Italia 404
VN - Vietnam 389
FI - Finlandia 371
FR - Francia 273
GB - Regno Unito 234
IN - India 150
SE - Svezia 148
CA - Canada 101
ZA - Sudafrica 101
AR - Argentina 66
JP - Giappone 66
BD - Bangladesh 63
MX - Messico 51
BE - Belgio 47
IQ - Iraq 46
ES - Italia 39
PL - Polonia 33
NL - Olanda 29
CO - Colombia 28
VE - Venezuela 28
ID - Indonesia 25
LT - Lituania 24
PK - Pakistan 23
TR - Turchia 23
EC - Ecuador 22
CZ - Repubblica Ceca 18
AT - Austria 17
UZ - Uzbekistan 15
CL - Cile 13
MA - Marocco 11
PH - Filippine 11
KE - Kenya 10
MY - Malesia 10
PE - Perù 10
SA - Arabia Saudita 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
CH - Svizzera 9
PY - Paraguay 9
IR - Iran 8
JO - Giordania 8
AZ - Azerbaigian 7
KR - Corea 7
UY - Uruguay 7
AL - Albania 6
BG - Bulgaria 6
EG - Egitto 6
KG - Kirghizistan 6
PA - Panama 6
PT - Portogallo 6
AM - Armenia 5
DO - Repubblica Dominicana 5
DZ - Algeria 5
EU - Europa 5
IL - Israele 5
KH - Cambogia 5
KZ - Kazakistan 5
RO - Romania 5
TT - Trinidad e Tobago 5
BO - Bolivia 4
CI - Costa d'Avorio 4
DK - Danimarca 4
JM - Giamaica 4
LK - Sri Lanka 4
MU - Mauritius 4
NP - Nepal 4
PS - Palestinian Territory 4
RS - Serbia 4
SN - Senegal 4
CR - Costa Rica 3
GR - Grecia 3
GY - Guiana 3
HU - Ungheria 3
LB - Libano 3
LV - Lettonia 3
TH - Thailandia 3
AO - Angola 2
CU - Cuba 2
EE - Estonia 2
GA - Gabon 2
HR - Croazia 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
MG - Madagascar 2
ML - Mali 2
MN - Mongolia 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
ZM - Zambia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
Totale 15.805
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Città #
Dublin 928
Chandler 882
Ashburn 547
Singapore 543
Beijing 540
Dallas 505
Jacksonville 504
Hong Kong 494
San Jose 494
Nanjing 461
Boardman 237
Los Angeles 191
Nanchang 180
Ann Arbor 160
Ho Chi Minh City 150
Lauterbourg 147
Princeton 146
Lawrence 140
New York 139
Helsinki 134
Munich 133
Hebei 129
Pavia 124
Shanghai 123
Wilmington 118
Shenyang 117
Medford 113
Changsha 107
Johannesburg 92
Jiaxing 91
Moscow 90
Hanoi 78
Tianjin 77
Hangzhou 72
Redondo Beach 63
Buffalo 60
Tokyo 59
Milan 57
Pune 54
São Paulo 52
Orem 48
Toronto 44
Brussels 42
Santa Clara 39
Chennai 37
Piscataway 37
Seattle 37
Woodbridge 37
The Dalles 35
Turku 34
London 31
Frankfurt am Main 29
Stockholm 29
Chicago 28
Warsaw 28
Denver 27
Montreal 27
Norwalk 23
Da Nang 22
Dearborn 22
Manchester 22
Amsterdam 19
Columbus 19
Mexico City 19
Phoenix 19
Atlanta 18
Fairfield 18
Houston 17
Poplar 17
Brooklyn 16
Florence 16
Nuremberg 16
Boston 15
Rome 15
Tashkent 15
Zhengzhou 15
Council Bluffs 14
Haiphong 14
Verona 14
Baghdad 13
Curitiba 13
San Francisco 13
Rio de Janeiro 12
Basingstoke 11
Guangzhou 11
Washington 11
Jinan 10
New Delhi 10
Salvador 10
Biên Hòa 9
Brasília 9
Caracas 9
Couilly-pont-aux-dames 9
Des Moines 9
Nairobi 9
Naples 9
Vienna 9
Dhaka 8
Erbil 8
Newark 8
Totale 10.515
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Nome #
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 165
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 157
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 152
Approaches for multi-gram scale isolation of enantiomers for drug discovery 147
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 146
Formulation of microspheres containing Crataegus monogyna extract in feed design 146
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 145
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 145
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 143
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 143
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 142
Progettazione e Sintesi di nuovi Ligandi Sigma 141
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 140
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 138
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 137
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 137
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 136
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 136
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 135
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 135
Novel sigma ligands: design, preparation and biological evaluation 134
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 132
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 132
Sigma receptor modulators: a patent review. 131
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 131
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 130
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 129
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 129
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 129
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 128
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 127
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 127
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 126
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 126
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 126
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 125
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 125
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 124
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 124
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 123
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 123
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 122
Design, synthesis and pharmacological activity of new antinociceptive agents 122
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 122
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 122
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 121
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 120
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 120
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 119
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 118
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 118
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 116
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 116
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 115
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 115
Chiral arylpyrrolidinols: preparation and biological profile 114
MW-assisted Fischer synthesis of new indolylimidazole and indolyltriazole derivatives 114
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 114
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 113
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 113
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 113
Are sigma receptor modulators a weapon against multiple sclerosis disease? 113
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 112
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 111
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 111
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 109
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 109
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 108
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 107
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 106
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies 106
The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material 106
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 106
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 105
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 105
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment 104
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy 104
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity 103
Discovery of Small Peptides Derived from Embryonic Lethal Abnormal Vision Proteins Structure Showing RNA-Stabilizing Properties 102
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 102
Enantioselective Modulatory Effects of Naringenin Enantiomers on the Expression Levels of miR‐17‐3p Involved in Endogenous Antioxidant Defenses 101
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 101
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 99
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 99
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 99
PKC in regenerative therapy: New insights for old targets 99
New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative 99
PEG 400/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds 98
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach 98
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 98
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 97
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 96
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 96
CHAPTER 12: Sigma Receptors as New Target for Multiple Sclerosis 95
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 94
Phytochemical and biological profile of Eremurus persicus Boiss root extract: isolation of the main phytocomponents. 94
3D pharmacophore model of sigma1 binding site based on a series of subtitued benzo[d]oxazol-2(3H)-one derivatives. 94
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 93
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 93
Synthesis and biological evaluation of small peptides able to mimic ELAV RNA-binding proteins: new perspective in neurodegenerative diseases treatment 89
Totale 11.855
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Categoria #
all - tutte 60.951
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.951
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021231 0 0 0 0 0 0 0 0 0 119 90 22
2021/2022704 10 5 29 12 9 21 13 52 40 30 93 390
2022/20232.456 234 222 26 173 238 249 0 135 1.075 15 60 29
2023/20241.039 117 166 24 48 97 261 65 72 5 40 79 65
2024/20252.656 43 190 73 80 132 185 138 148 663 100 311 593
2025/20265.567 487 326 769 680 845 249 1.048 251 554 358 0 0
Totale 16.062