IRIS
ROSSI, DANIELA
 Distribuzione geografica
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Continente #
NA - Nord America 6.464
AS - Asia 4.834
EU - Europa 3.982
SA - Sud America 686
AF - Africa 173
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 1
Totale 16.147
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Nazione #
US - Stati Uniti d'America 6.271
CN - Cina 2.388
SG - Singapore 993
IE - Irlanda 931
HK - Hong Kong 510
BR - Brasile 496
RU - Federazione Russa 491
DE - Germania 443
IT - Italia 418
UA - Ucraina 405
VN - Vietnam 389
FI - Finlandia 371
FR - Francia 273
GB - Regno Unito 234
IN - India 151
SE - Svezia 148
CA - Canada 112
ZA - Sudafrica 101
BD - Bangladesh 75
AR - Argentina 66
JP - Giappone 66
MX - Messico 53
BE - Belgio 47
IQ - Iraq 46
ES - Italia 39
PL - Polonia 33
NL - Olanda 30
CO - Colombia 28
VE - Venezuela 28
ID - Indonesia 25
LT - Lituania 25
PK - Pakistan 23
TR - Turchia 23
EC - Ecuador 22
CZ - Repubblica Ceca 18
AT - Austria 17
UZ - Uzbekistan 15
CL - Cile 13
MA - Marocco 11
PH - Filippine 11
CH - Svizzera 10
KE - Kenya 10
MY - Malesia 10
PE - Perù 10
SA - Arabia Saudita 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
PY - Paraguay 9
IR - Iran 8
JO - Giordania 8
KR - Corea 8
AZ - Azerbaigian 7
UY - Uruguay 7
AL - Albania 6
BG - Bulgaria 6
EG - Egitto 6
KG - Kirghizistan 6
PA - Panama 6
PT - Portogallo 6
AM - Armenia 5
DO - Repubblica Dominicana 5
DZ - Algeria 5
EU - Europa 5
IL - Israele 5
KH - Cambogia 5
KZ - Kazakistan 5
RO - Romania 5
TT - Trinidad e Tobago 5
BO - Bolivia 4
CI - Costa d'Avorio 4
CR - Costa Rica 4
DK - Danimarca 4
JM - Giamaica 4
LK - Sri Lanka 4
MU - Mauritius 4
NP - Nepal 4
PS - Palestinian Territory 4
RS - Serbia 4
SN - Senegal 4
GR - Grecia 3
GY - Guiana 3
HU - Ungheria 3
LB - Libano 3
LV - Lettonia 3
TH - Thailandia 3
AO - Angola 2
CU - Cuba 2
EE - Estonia 2
ET - Etiopia 2
GA - Gabon 2
HR - Croazia 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
MG - Madagascar 2
ML - Mali 2
MN - Mongolia 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
ZM - Zambia 2
Totale 16.128
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Città #
Dublin 928
Chandler 882
San Jose 595
Ashburn 571
Beijing 549
Singapore 549
Dallas 512
Jacksonville 505
Hong Kong 496
Nanjing 461
Boardman 238
Los Angeles 199
Nanchang 180
Ann Arbor 160
Ho Chi Minh City 150
Lauterbourg 147
Princeton 146
New York 144
Lawrence 140
Helsinki 134
Munich 133
Hebei 129
Pavia 124
Shanghai 123
Wilmington 118
Shenyang 117
Medford 113
Changsha 107
Johannesburg 92
Jiaxing 91
Moscow 90
Hanoi 78
Tianjin 77
Hangzhou 72
Council Bluffs 65
Redondo Beach 63
Buffalo 61
Milan 59
Tokyo 59
Pune 54
São Paulo 52
Santa Clara 49
Orem 48
Toronto 46
Brussels 42
Chennai 37
Piscataway 37
Seattle 37
Woodbridge 37
The Dalles 35
Turku 34
London 31
Chicago 29
Denver 29
Frankfurt am Main 29
Montreal 29
Stockholm 29
Warsaw 28
Norwalk 23
Da Nang 22
Dearborn 22
Manchester 22
Mexico City 21
Amsterdam 19
Columbus 19
Houston 19
Phoenix 19
Atlanta 18
Fairfield 18
Poplar 17
Brooklyn 16
Florence 16
Nuremberg 16
Boston 15
Rome 15
Tashkent 15
Zhengzhou 15
Haiphong 14
San Francisco 14
Verona 14
Baghdad 13
Curitiba 13
Rio de Janeiro 12
Basingstoke 11
Guangzhou 11
Naples 11
Washington 11
Jinan 10
New Delhi 10
Salvador 10
Biên Hòa 9
Brasília 9
Caracas 9
Couilly-pont-aux-dames 9
Des Moines 9
Nairobi 9
Vienna 9
Dhaka 8
Erbil 8
Miami 8
Totale 10.757
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Nome #
A step forward in understanding the binding of ELAV mimicking peptides to mRNA. An integrated computational and NMR approach 170
(R)-RC-33 as Promising Neuroprotective Agent Acting as Sigma1 Receptor Agonist 162
Fingerprint Analitico di estratti da Amygdalus Lycioides (Spach.) 152
Formulation of microspheres containing Crataegus monogyna extract in feed design 151
Approaches for multi-gram scale isolation of enantiomers for drug discovery 148
A step forward in the sigma enigma: a role for chirality in the sigma1 receptor- ligand interaction? 147
3-Piperidin-4-ylmethyl-3H-benzoxazol-2-one derivatives as sigma ligands 146
An eco-friendly enantioselective access to (R)-Naringenin as inhibitor of proinflammatory cytokine release. 146
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile 146
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds, promising neuroprotective agents acting as sigma1 receptor agonists. 144
Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2) 144
Progettazione e Sintesi di nuovi Ligandi Sigma 141
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands 141
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability. 139
Anti-inflammatory properties of ethanolic root extract of Eremurus persicus (Jaub and Spach) Boiss, a Kurdish herbal remedy 139
Marrubium vulgare l. leave extract: Phytochemical composition, antioxidant and wound healing properties 139
New perspectives in cancer therapy: the biotin-antitumor molecule conjugates 138
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library 136
Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation 135
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer 135
Novel sigma ligands: design, preparation and biological evaluation 134
(R)-(-)-Aloesaponol III 8-methyl ether from eremurus persicus: A novel compound against leishmaniosis 134
Design, synthesis and biological evaluation of new sigma ligands based on arylalkenylaminic scaffold 133
An efficient procedure based on MW-assisted Horner–Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted alpha, beta-unsaturated esters 133
Sigma receptor modulators: a patent review. 131
Direct HPLC enantioseparation of new chiral sigma 1 ligands on coated polisaccharide-based chiral stationary phases. 131
Synthesis of novel sigma ligands. Investigation on the application of Pd(0) EnCatTM 30NP in conventional hydrogenation and CTH MW-assisted protocols 130
Influence of the Extraction Mode on the Yield of Hyperoside, Vitexin and Vitexin-2”-O-Rhamnoside from Crataegus monogyna Jacq. (Hawthorn) 130
Eremurus persicus Boiss: ethnobotanical relevance, analytical fingerprint and preliminary biological results of root extracts 130
Gaining in Pan-Affinity Towards Sigma 1 and Sigma 2 Receptors. SAR studies on arylalkylamines 130
Synthesis and Pharmacological Evaluation of New N-methyl-arylpyrrolidinols with Analgesic Activity 130
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. 130
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies 129
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: potential sigma 1 ligands. 128
ARE we stable? An integrated in vitro/in silico approach for the study of Embryonic Lethal Abnormal Vision protein and mRNA interactions. 128
Drug discovery from plants: antimicrobial evaluation of Amygdalus lycioides (Spach.) branch extracts 126
Discovery of new and selective sigma 1 ligands potentiating nerve growth factor induced neurite outgrowth in PC12 cells 126
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. 126
Microwave and Polymer Assisted Synthesis of a Small Library of alpha,beta-Unsaturated Methyl Esters via the Witting Reaction 125
PAN-SIGMA RECEPTOR MODULATORS AS PROMISING ANTICANCER-AGENTS. THE STORY OF RC-106 125
An Analytical and Scale-Up Separation by HPLC and SFC of theFlavonoid Naringenin on a RegisPack® Chiral Stationary Phase 125
Design, synthesis and pharmacological activity of new antinociceptive agents 124
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016). 124
Identification of Peptides with ELAV-like mRNA Stabilizing Effect: An Integrated In Vitro/In Silico Approach 124
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds 124
A step forward in the sigma enigma: the role of chirality in the interaction ligand-sigma1 receptor 123
Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents 123
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition 121
NOVEL PKC ALPHA LIGANDS: RATIONAL DESIGN, PREPARATION AND BIOLOGICAL INVESTIGATION 119
Epigenetic effect of naringenin: effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p expression levels. 119
One-pot synthesis of alfa,beta-unsaturated carboxylic acid via tandem Wittig olefination-hydrolysis reaction under combined microwave and ultrasound irradiation. 118
IDENTIFICATION OF NEW LIGANDS FOR SIGMA RECEPTORS.DESIGN AND SYNTHESIS OF A BETA-AMINOKETONIC DRUG DISCOVERY LIBRARY 118
Chiral arylpyrrolidinols: preparation and biological profile 117
In silico exploration of the Embryonic Lethal Abnormal Visionprotein-mRNA interaction followed by in vitro bioassays for the identification of peptides potentially useful in neurodegenerative diseases treatment 117
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists. 117
Are sigma receptor modulators a weapon against multiple sclerosis disease? 116
FLAVANONES FROM AMYGDALUS LYCIOIDES SPACH: ISOLATION, CHARACTERIZATION AND BIOLOGICAL EVALUATION 115
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity. 115
MW-assisted Fischer synthesis of new indolylimidazole and indolyltriazole derivatives 114
New biotinilated spacers for studying the interaction of ELAV mimicking peptides with the target mRNA 114
Towards sigma1 receptor agonists as neuroprotective agents. Preparation, configurational assignment and in vitro biological profile 114
Small peptides able to mimic ELAV RNA-binding proteins: preparation and biological evaluation 113
Enantioselective modulatory effects of (S)-naringenin and (R)-naringenin on miR-17-3p and miR-25-5p 113
New perspectives in neurodegenerative diseases: chiral resolution and configurational assignment of novel PKC alpha ligands 112
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 112
Beyond the affinity for the Protein Kinase C: a critical evaluation of 2-fenil-3hydroxypropyl pivalate analogs targeting the C1 domain 111
Antibacterial activity of Amygdalus Lycioides (Spach.): screening of different branch extracts 110
The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material 110
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimetylamino-2-methylpentan-3-one 109
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 109
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 109
DRUG DISCOVERY FROM PLANTS: TRADITIONAL HERBAL REMEDIES AS SOURCE FOR NEW LEAD COMPOUNDS 108
High-Throughput Lipophilicity Screening of Opioid-Like Analgesics: Validation of Computational Methods by Means of RP-HPLC Analysis 107
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target 106
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies 106
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment 106
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3 Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy 106
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 105
Polymer-Assisted Solution-Phase Synthesis under combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 105
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity 104
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application 104
Discovery of Small Peptides Derived from Embryonic Lethal Abnormal Vision Proteins Structure Showing RNA-Stabilizing Properties 102
Novel chiral sigma 1 receptor ligand potentiating NGF-induced neurite outgrowth in PC12 cells 101
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3beta 101
Enantioselective Modulatory Effects of Naringenin Enantiomers on the Expression Levels of miR‐17‐3p Involved in Endogenous Antioxidant Defenses 101
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach 100
New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative 100
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 100
Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of alpha,beta-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands. 99
PKC in regenerative therapy: New insights for old targets 99
PEG 400/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds 98
In vivo pharmacokinetic study and CNS distribution of the sigma1 receptor agonist (R)-RC-33, a promising neuroprotective agent 97
Microspheres containing an extract of Crataegus monogyna Jacq. for oral administration. 96
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents 96
CHAPTER 12: Sigma Receptors as New Target for Multiple Sclerosis 96
Phytochemical and biological profile of Eremurus persicus Boiss root extract: isolation of the main phytocomponents. 95
Synthesis and in vitro evaluation of novel pan-SR modulators: Identification of (E)-4-benzyl-1-[3-(naphthalen-2-yl)but-2-en-1-yl]piperidine (RC-106) as potential anticancer agent. 95
3D pharmacophore model of sigma1 binding site based on a series of subtitued benzo[d]oxazol-2(3H)-one derivatives. 95
Preliminary study on TNF alpha-blocker activity of Amygdalus lycioides Spach extracts 94
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 92
Totale 12.011
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Categoria #
all - tutte 64.720
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.720
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202122 0 0 0 0 0 0 0 0 0 0 0 22
2021/2022704 10 5 29 12 9 21 13 52 40 30 93 390
2022/20232.456 234 222 26 173 238 249 0 135 1.075 15 60 29
2023/20241.039 117 166 24 48 97 261 65 72 5 40 79 65
2024/20252.656 43 190 73 80 132 185 138 148 663 100 311 593
2025/20265.891 487 326 769 680 845 249 1.048 251 554 433 144 105
Totale 16.386