IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.060
AS - Asia 3.685
EU - Europa 3.138
SA - Sud America 474
AF - Africa 160
OC - Oceania 13
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.532
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Nazione #
US - Stati Uniti d'America 4.911
CN - Cina 1.721
SG - Singapore 789
IE - Irlanda 705
HK - Hong Kong 386
RU - Federazione Russa 371
DE - Germania 368
BR - Brasile 357
VN - Vietnam 341
FI - Finlandia 328
UA - Ucraina 328
IT - Italia 319
FR - Francia 180
SE - Svezia 166
GB - Regno Unito 158
IN - India 105
ZA - Sudafrica 103
CA - Canada 86
BD - Bangladesh 55
JP - Giappone 49
MX - Messico 38
IQ - Iraq 35
ES - Italia 33
PL - Polonia 32
TR - Turchia 31
AT - Austria 29
AR - Argentina 28
NL - Olanda 24
BE - Belgio 23
CO - Colombia 22
ID - Indonesia 19
EC - Ecuador 18
VE - Venezuela 17
PK - Pakistan 16
CZ - Repubblica Ceca 13
SA - Arabia Saudita 13
LT - Lituania 12
UZ - Uzbekistan 12
AU - Australia 11
BO - Bolivia 10
MA - Marocco 10
MY - Malesia 10
PH - Filippine 10
CL - Cile 9
AZ - Azerbaigian 8
JO - Giordania 8
KE - Kenya 8
KR - Corea 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
PE - Perù 7
TN - Tunisia 7
CR - Costa Rica 6
EG - Egitto 6
HU - Ungheria 6
KZ - Kazakistan 6
OM - Oman 6
CH - Svizzera 5
GR - Grecia 5
IL - Israele 5
KG - Kirghizistan 5
TH - Thailandia 5
DK - Danimarca 4
JM - Giamaica 4
LV - Lettonia 4
NG - Nigeria 4
PA - Panama 4
PY - Paraguay 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HR - Croazia 3
LB - Libano 3
NP - Nepal 3
PS - Palestinian Territory 3
AL - Albania 2
AM - Armenia 2
CG - Congo 2
DZ - Algeria 2
ET - Etiopia 2
GA - Gabon 2
GT - Guatemala 2
LK - Sri Lanka 2
MU - Mauritius 2
NA - Namibia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
RE - Reunion 2
RO - Romania 2
UY - Uruguay 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
CM - Camerun 1
Totale 12.512
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Città #
Dublin 705
Chandler 672
San Jose 518
Ashburn 488
Singapore 448
Jacksonville 426
Beijing 381
Hong Kong 372
Dallas 318
Nanjing 310
Boardman 208
Los Angeles 136
Helsinki 132
Ho Chi Minh City 124
Pavia 124
Nanchang 120
Wilmington 110
Princeton 106
Medford 103
Lauterbourg 102
Lawrence 102
New York 95
Ann Arbor 93
Munich 93
Shenyang 93
Changsha 91
Johannesburg 87
Jiaxing 79
Hebei 76
Hanoi 75
Shanghai 67
Tianjin 60
Council Bluffs 59
Hangzhou 56
Moscow 53
Buffalo 52
Tokyo 48
Santa Clara 45
Milan 41
Redondo Beach 40
Orem 35
Turku 35
Woodbridge 32
Warsaw 30
The Dalles 28
Ottawa 27
San Francisco 26
Frankfurt am Main 24
São Paulo 24
Vienna 24
Montreal 23
Chicago 22
Stockholm 22
Piscataway 21
Brussels 20
Falkenstein 20
Chennai 19
Brooklyn 18
Da Nang 18
London 18
Toronto 18
Verona 17
Denver 16
Guangzhou 16
Norwalk 16
Columbus 15
Haiphong 15
Houston 14
Mexico City 14
Seattle 14
Boston 13
Dearborn 13
Mumbai 13
Phoenix 13
Amsterdam 12
Olomouc 12
Atlanta 11
Baghdad 11
Brasília 11
Fairfield 11
Nuremberg 11
Paris 11
Rome 11
San Genesio ed Uniti 11
Falls Church 10
Istanbul 10
Tashkent 10
Belo Horizonte 9
Biên Hòa 9
Madrid 9
Manchester 9
New Delhi 9
Poplar 9
Pune 9
Amman 8
Chongqing 8
Jinan 8
Porto Alegre 8
Washington 8
Baku 7
Totale 8.253
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 208
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 179
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 166
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 163
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 159
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 157
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 152
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 151
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 150
A census of RND superfamily proteins in the Burkholderia genus. 149
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 149
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 144
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 144
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 143
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 143
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 143
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 141
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 140
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 138
MmpL3 is the cellular target of the antitubercular drug BM212. 138
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 137
Identification of cellular targets of new antitubercular drugs. 134
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 132
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 130
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 130
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 129
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 127
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 127
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 127
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 126
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 126
New prodrugs against tuberculosis 126
Azole drug resistance in Mycobacterium tuberculosis 125
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 125
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 123
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 123
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 123
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 123
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 122
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 122
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 120
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 120
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 119
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 118
New and old hot drug targets in tuberculosis 118
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 115
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 115
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 115
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 114
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 113
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 111
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 111
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 110
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 110
DprE1, a new taxonomic marker in mycobacteria. 110
Mycobacterium tuberculosis: drug resistance and future perspectives 110
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 110
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 110
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 110
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 109
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 109
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 108
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 107
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 106
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 105
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 104
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 103
First triclosan-based macrocyclic inhibitors of InhA enzyme 103
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 101
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 101
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 101
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 98
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 98
Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. 97
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 96
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 95
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 94
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 93
Nitric oxide-releasing compounds for the treatment of lung infections 93
New medicines against tuberculosis. 92
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 92
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 91
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 90
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 90
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 90
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 90
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 89
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 88
Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis. 87
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 87
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 87
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 86
Molecular basis for antibiotic resistance in the genus Burkholderia 85
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 84
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 84
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 82
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options 80
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 80
Iron acquisition pathways as targets for antitubercular drugs. 80
Editorial: New Approaches Against Drug-Resistant M. tuberculosis 78
Totale 11.586
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Categoria #
all - tutte 49.878
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.878
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202121 0 0 0 0 0 0 0 0 0 0 0 21
2021/2022558 16 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/20251.990 44 135 65 53 94 164 91 116 506 71 230 421
2025/20264.575 369 256 533 450 619 223 867 200 435 355 163 105
Totale 12.847