IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.803
AS - Asia 3.628
EU - Europa 3.123
SA - Sud America 474
AF - Africa 160
OC - Oceania 13
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.203
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Nazione #
US - Stati Uniti d'America 4.663
CN - Cina 1.712
SG - Singapore 771
IE - Irlanda 705
HK - Hong Kong 381
RU - Federazione Russa 370
DE - Germania 368
BR - Brasile 357
VN - Vietnam 341
FI - Finlandia 328
UA - Ucraina 328
IT - Italia 305
FR - Francia 180
SE - Svezia 166
GB - Regno Unito 158
IN - India 103
ZA - Sudafrica 103
CA - Canada 81
JP - Giappone 48
MX - Messico 37
BD - Bangladesh 35
IQ - Iraq 35
ES - Italia 33
PL - Polonia 32
AT - Austria 29
TR - Turchia 29
AR - Argentina 28
NL - Olanda 24
BE - Belgio 23
CO - Colombia 22
ID - Indonesia 19
EC - Ecuador 18
VE - Venezuela 17
PK - Pakistan 16
CZ - Repubblica Ceca 13
SA - Arabia Saudita 13
LT - Lituania 12
UZ - Uzbekistan 12
AU - Australia 11
BO - Bolivia 10
MA - Marocco 10
MY - Malesia 10
PH - Filippine 10
CL - Cile 9
AZ - Azerbaigian 8
JO - Giordania 8
KE - Kenya 8
KR - Corea 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
PE - Perù 7
TN - Tunisia 7
EG - Egitto 6
HU - Ungheria 6
KZ - Kazakistan 6
OM - Oman 6
CH - Svizzera 5
CR - Costa Rica 5
GR - Grecia 5
IL - Israele 5
KG - Kirghizistan 5
TH - Thailandia 5
DK - Danimarca 4
LV - Lettonia 4
NG - Nigeria 4
PA - Panama 4
PY - Paraguay 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HR - Croazia 3
LB - Libano 3
NP - Nepal 3
PS - Palestinian Territory 3
AL - Albania 2
AM - Armenia 2
CG - Congo 2
DZ - Algeria 2
ET - Etiopia 2
GA - Gabon 2
GT - Guatemala 2
JM - Giamaica 2
LK - Sri Lanka 2
MU - Mauritius 2
NA - Namibia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
RE - Reunion 2
RO - Romania 2
UY - Uruguay 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
CM - Camerun 1
Totale 12.183
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Città #
Dublin 705
Chandler 672
Ashburn 464
Singapore 445
Jacksonville 425
San Jose 422
Beijing 375
Hong Kong 367
Dallas 316
Nanjing 310
Boardman 190
Los Angeles 135
Helsinki 132
Ho Chi Minh City 124
Pavia 124
Nanchang 120
Wilmington 109
Princeton 106
Medford 103
Lauterbourg 102
Lawrence 102
Ann Arbor 93
Munich 93
Shenyang 93
Changsha 91
New York 89
Johannesburg 87
Jiaxing 79
Hebei 76
Hanoi 75
Shanghai 67
Tianjin 60
Hangzhou 56
Moscow 53
Buffalo 50
Tokyo 47
Redondo Beach 40
Milan 39
Santa Clara 37
Turku 35
Orem 34
Woodbridge 31
Warsaw 30
The Dalles 28
Ottawa 27
Frankfurt am Main 24
San Francisco 24
São Paulo 24
Vienna 24
Stockholm 22
Montreal 21
Piscataway 21
Brussels 20
Chicago 20
Falkenstein 20
Chennai 19
Brooklyn 18
Da Nang 18
London 18
Toronto 18
Verona 17
Denver 16
Guangzhou 16
Norwalk 16
Columbus 15
Council Bluffs 15
Haiphong 15
Seattle 14
Dearborn 13
Houston 13
Mexico City 13
Mumbai 13
Amsterdam 12
Boston 12
Olomouc 12
Phoenix 12
Baghdad 11
Brasília 11
Nuremberg 11
Paris 11
Rome 11
San Genesio ed Uniti 11
Atlanta 10
Fairfield 10
Falls Church 10
Tashkent 10
Belo Horizonte 9
Biên Hòa 9
Istanbul 9
Madrid 9
Manchester 9
New Delhi 9
Poplar 9
Pune 9
Amman 8
Chongqing 8
Jinan 8
Porto Alegre 8
Washington 8
Baku 7
Totale 8.018
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 202
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 171
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 161
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 159
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 156
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 155
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 149
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 149
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 149
A census of RND superfamily proteins in the Burkholderia genus. 145
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 141
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 141
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 141
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 140
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 140
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 140
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 139
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 138
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 135
MmpL3 is the cellular target of the antitubercular drug BM212. 135
Identification of cellular targets of new antitubercular drugs. 133
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 133
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 130
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 129
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 128
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 127
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 127
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 126
New prodrugs against tuberculosis 126
Azole drug resistance in Mycobacterium tuberculosis 125
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 125
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 125
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 124
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 123
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 121
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 121
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 121
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 119
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 119
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 118
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 116
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 115
New and old hot drug targets in tuberculosis 115
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 114
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 113
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 112
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 112
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 112
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 111
DprE1, a new taxonomic marker in mycobacteria. 110
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 110
Mycobacterium tuberculosis: drug resistance and future perspectives 109
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 108
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 108
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 108
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 107
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 106
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 106
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 106
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 105
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 104
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 103
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 103
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 102
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 101
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 101
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 101
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 101
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 100
First triclosan-based macrocyclic inhibitors of InhA enzyme 100
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 97
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 97
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 96
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 92
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 92
New medicines against tuberculosis. 91
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 91
Nitric oxide-releasing compounds for the treatment of lung infections 91
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 90
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 90
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 89
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 89
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 88
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 88
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 88
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 88
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 87
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 85
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 85
Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. 84
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 84
Molecular basis for antibiotic resistance in the genus Burkholderia 84
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 81
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 81
Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis. 80
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 80
Iron acquisition pathways as targets for antitubercular drugs. 78
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 77
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053. 77
Editorial: New Approaches Against Drug-Resistant M. tuberculosis 77
Totale 11.302
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Categoria #
all - tutte 46.762
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.762
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021209 0 0 0 0 0 0 0 0 0 98 90 21
2021/2022558 16 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/20251.990 44 135 65 53 94 164 91 116 506 71 230 421
2025/20264.246 369 256 533 450 619 223 867 200 435 294 0 0
Totale 12.518