IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.151
AS - Asia 2.902
EU - Europa 2.874
SA - Sud America 386
AF - Africa 41
OC - Oceania 10
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 10.366
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Nazione #
US - Stati Uniti d'America 4.027
CN - Cina 1.627
IE - Irlanda 701
SG - Singapore 588
RU - Federazione Russa 360
HK - Hong Kong 348
DE - Germania 346
FI - Finlandia 325
UA - Ucraina 325
BR - Brasile 319
IT - Italia 286
SE - Svezia 165
GB - Regno Unito 139
VN - Vietnam 117
CA - Canada 77
FR - Francia 47
IN - India 42
JP - Giappone 33
MX - Messico 30
PL - Polonia 30
AT - Austria 28
BE - Belgio 23
ES - Italia 23
AR - Argentina 21
TR - Turchia 21
NL - Olanda 20
BD - Bangladesh 16
ZA - Sudafrica 16
IQ - Iraq 14
EC - Ecuador 13
CZ - Repubblica Ceca 12
ID - Indonesia 12
CO - Colombia 10
LT - Lituania 10
AU - Australia 8
KR - Corea 8
AZ - Azerbaigian 7
JO - Giordania 7
SA - Arabia Saudita 7
PK - Pakistan 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
CL - Cile 5
HU - Ungheria 5
IL - Israele 5
PE - Perù 5
CR - Costa Rica 4
GR - Grecia 4
KG - Kirghizistan 4
KZ - Kazakistan 4
NG - Nigeria 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
TW - Taiwan 4
BO - Bolivia 3
BY - Bielorussia 3
CH - Svizzera 3
GE - Georgia 3
KE - Kenya 3
MA - Marocco 3
RS - Serbia 3
TN - Tunisia 3
UZ - Uzbekistan 3
AM - Armenia 2
AO - Angola 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GT - Guatemala 2
JM - Giamaica 2
LK - Sri Lanka 2
LV - Lettonia 2
NA - Namibia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
PT - Portogallo 2
PY - Paraguay 2
RO - Romania 2
UY - Uruguay 2
BB - Barbados 1
BH - Bahrain 1
CG - Congo 1
CY - Cipro 1
DZ - Algeria 1
EU - Europa 1
GA - Gabon 1
GH - Ghana 1
GM - Gambi 1
GS - Georgia del Sud e Isole Sandwich Australi 1
HR - Croazia 1
IM - Isola di Man 1
IR - Iran 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MD - Moldavia 1
MM - Myanmar 1
MU - Mauritius 1
Totale 10.359
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Città #
Dublin 701
Chandler 672
Jacksonville 425
Ashburn 381
Beijing 370
Hong Kong 340
Dallas 316
Singapore 313
Nanjing 310
Boardman 190
Helsinki 129
Los Angeles 124
Nanchang 120
Pavia 120
Wilmington 109
Princeton 106
Medford 103
Lawrence 102
Ann Arbor 93
Munich 93
Shenyang 93
Changsha 91
New York 84
Jiaxing 79
Hebei 76
Shanghai 67
Tianjin 60
Hangzhou 56
Moscow 52
Ho Chi Minh City 46
Buffalo 45
Redondo Beach 40
Milan 38
Turku 35
Tokyo 33
Woodbridge 31
Santa Clara 30
Hanoi 28
Warsaw 28
Ottawa 27
The Dalles 27
San Francisco 23
Vienna 23
São Paulo 22
Stockholm 21
Brussels 20
Falkenstein 20
Montreal 20
Chicago 19
Piscataway 18
Brooklyn 17
Verona 17
Guangzhou 16
Norwalk 16
Toronto 16
Columbus 15
Denver 15
London 14
Dearborn 13
Houston 13
Orem 13
Seattle 13
Boston 12
Olomouc 12
Phoenix 12
Brasília 11
San Genesio ed Uniti 11
Fairfield 10
Falls Church 10
Amsterdam 9
Atlanta 9
Belo Horizonte 9
Nuremberg 9
Poplar 9
Chennai 8
Chongqing 8
Jinan 8
Johannesburg 8
Mexico City 8
Rome 8
Washington 8
Amman 7
Frankfurt am Main 7
Mumbai 7
Porto Alegre 7
Rio de Janeiro 7
San Jose 7
Baku 6
Biên Hòa 6
Charlotte 6
Cinisello Balsamo 6
Ningbo 6
Riyadh 6
Taizhou 6
Auburn Hills 5
Guayaquil 5
Gunzenhausen 5
Haiphong 5
Kunming 5
Madrid 5
Totale 6.840
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 181
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 145
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 141
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 140
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 135
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 130
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 129
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 129
A census of RND superfamily proteins in the Burkholderia genus. 127
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 126
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 126
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 126
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 125
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 124
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 124
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 123
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 121
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 119
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 116
Identification of cellular targets of new antitubercular drugs. 115
New prodrugs against tuberculosis 115
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 113
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 112
MmpL3 is the cellular target of the antitubercular drug BM212. 112
Azole drug resistance in Mycobacterium tuberculosis 110
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 110
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 109
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 109
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 108
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 107
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 107
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 106
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 105
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 105
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 105
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 104
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 104
New and old hot drug targets in tuberculosis 104
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 103
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 102
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 102
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 101
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 101
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 99
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 98
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 98
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 98
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 97
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 97
DprE1, a new taxonomic marker in mycobacteria. 96
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 95
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 92
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 92
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 91
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 91
Mycobacterium tuberculosis: drug resistance and future perspectives 91
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 90
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 90
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 89
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 89
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 89
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 89
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 89
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 88
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 88
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 88
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 87
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 87
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 85
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 83
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 82
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 81
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 81
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 80
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 80
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 80
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 79
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 78
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 78
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 77
New medicines against tuberculosis. 77
Molecular basis for antibiotic resistance in the genus Burkholderia 77
Nitric oxide-releasing compounds for the treatment of lung infections 76
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 75
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 75
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 75
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 75
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 75
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 73
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 72
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053. 72
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 69
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 69
Iron acquisition pathways as targets for antitubercular drugs. 68
Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. 66
Caratterizzazione genetica e molecolare di un nuovo promotore nel gene hisG di S. typhimurium e ricerca di nuovi elementi coinvolti nella terminazione Rho-dipendente. 66
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 66
Suppression of transcriptional polarity by transcription or translation reinitiation in the histidine operon of Salmonella. 64
First triclosan-based macrocyclic inhibitors of InhA enzyme 64
Mycobacterium tuberculosis efflux pumps: an update 63
Totale 9.735
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Categoria #
all - tutte 43.512
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.512
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021490 0 0 0 0 0 82 18 140 41 98 90 21
2021/2022558 16 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/20251.990 44 135 65 53 94 164 91 116 506 71 230 421
2025/20262.406 369 256 533 450 619 179 0 0 0 0 0 0
Totale 10.678