IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 6.139
AS - Asia 3.732
EU - Europa 3.322
SA - Sud America 496
Continente sconosciuto - Info sul continente non disponibili 329
AF - Africa 172
OC - Oceania 13
AN - Antartide 1
Totale 14.204
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Nazione #
US - Stati Uniti d'America 5.873
CN - Cina 1.728
SG - Singapore 798
IE - Irlanda 706
IT - Italia 454
HK - Hong Kong 390
RU - Federazione Russa 385
DE - Germania 368
BR - Brasile 366
VN - Vietnam 341
UA - Ucraina 332
FI - Finlandia 328
FR - Francia 183
GB - Regno Unito 171
SE - Svezia 167
CA - Canada 135
IN - India 106
ZA - Sudafrica 103
BD - Bangladesh 59
JP - Giappone 49
MX - Messico 38
IQ - Iraq 35
ES - Italia 34
AR - Argentina 33
PL - Polonia 32
TR - Turchia 31
AT - Austria 29
NL - Olanda 28
ID - Indonesia 26
CO - Colombia 25
BE - Belgio 23
EC - Ecuador 19
VE - Venezuela 18
CR - Costa Rica 17
PK - Pakistan 17
IL - Israele 16
CZ - Repubblica Ceca 14
SA - Arabia Saudita 14
HN - Honduras 12
LT - Lituania 12
SC - Seychelles 12
UZ - Uzbekistan 12
AU - Australia 11
GT - Guatemala 11
SV - El Salvador 11
BO - Bolivia 10
CL - Cile 10
MA - Marocco 10
MY - Malesia 10
PH - Filippine 10
JM - Giamaica 9
AZ - Azerbaigian 8
JO - Giordania 8
KE - Kenya 8
KR - Corea 8
PE - Perù 8
TT - Trinidad e Tobago 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
CW - ???statistics.table.value.countryCode.CW??? 7
HU - Ungheria 7
KZ - Kazakistan 7
TN - Tunisia 7
EG - Egitto 6
KG - Kirghizistan 6
NI - Nicaragua 6
OM - Oman 6
CH - Svizzera 5
DK - Danimarca 5
GR - Grecia 5
PA - Panama 5
PY - Paraguay 5
RS - Serbia 5
TH - Thailandia 5
GP - Guadalupe 4
LV - Lettonia 4
NG - Nigeria 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HR - Croazia 3
LB - Libano 3
NP - Nepal 3
PR - Porto Rico 3
PS - Palestinian Territory 3
AL - Albania 2
AM - Armenia 2
CG - Congo 2
DZ - Algeria 2
EE - Estonia 2
ET - Etiopia 2
GA - Gabon 2
LK - Sri Lanka 2
MU - Mauritius 2
NA - Namibia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
Totale 13.852
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Città #
Dublin 705
Chandler 673
San Jose 580
Ashburn 571
Singapore 453
Jacksonville 428
Beijing 383
Hong Kong 374
Dallas 326
Nanjing 310
Council Bluffs 287
Boardman 208
Los Angeles 144
Helsinki 132
Pavia 126
Ho Chi Minh City 124
Nanchang 120
Wilmington 110
Princeton 107
Medford 103
New York 103
Lauterbourg 102
Lawrence 102
Ann Arbor 93
Munich 93
Shenyang 93
Changsha 91
Johannesburg 87
Jiaxing 79
Hebei 76
Hanoi 75
Santa Clara 71
Shanghai 68
Tianjin 60
Hangzhou 56
Buffalo 54
Moscow 53
Milan 50
Tokyo 48
Redondo Beach 40
Orem 35
Turku 35
Woodbridge 32
Montreal 31
Warsaw 30
The Dalles 29
Columbus 28
San Francisco 28
Brooklyn 27
Ottawa 27
São Paulo 27
Chicago 26
Frankfurt am Main 24
Rome 24
Vienna 24
Stockholm 23
Phoenix 22
Toronto 22
Piscataway 21
Brussels 20
Falkenstein 20
Houston 20
Boston 19
Chennai 19
London 19
Verona 19
Da Nang 18
Naples 18
Seattle 18
Norwalk 17
Denver 16
Guangzhou 16
Haiphong 15
Amsterdam 14
Atlanta 14
Mexico City 14
San José 14
Brasília 13
Dearborn 13
Mumbai 13
Olomouc 12
Baghdad 11
Charlotte 11
Fairfield 11
Manchester 11
Nuremberg 11
Paris 11
San Genesio ed Uniti 11
Falls Church 10
Istanbul 10
San Salvador 10
Tashkent 10
Washington 10
Belo Horizonte 9
Biên Hòa 9
Madrid 9
New Delhi 9
Poplar 9
Porto Alegre 9
Pune 9
Totale 8.824
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 221
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 191
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 179
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 178
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 175
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 171
A census of RND superfamily proteins in the Burkholderia genus. 166
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 163
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 161
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 160
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 160
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 160
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 158
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 156
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 155
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 154
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 153
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 153
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 151
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 148
MmpL3 is the cellular target of the antitubercular drug BM212. 148
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 144
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 140
Identification of cellular targets of new antitubercular drugs. 140
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 140
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 140
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 139
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 139
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 138
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 136
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 136
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 135
Azole drug resistance in Mycobacterium tuberculosis 134
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 133
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 133
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 133
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 133
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 132
New prodrugs against tuberculosis 131
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 130
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 129
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 128
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 127
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 127
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 127
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 127
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 127
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 125
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 125
New and old hot drug targets in tuberculosis 125
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 121
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 120
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 120
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 119
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 119
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 119
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 119
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 118
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 117
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 117
Mycobacterium tuberculosis: drug resistance and future perspectives 117
DprE1, a new taxonomic marker in mycobacteria. 116
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 115
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 115
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 115
Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. 113
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 113
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 112
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 112
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 111
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 111
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 110
First triclosan-based macrocyclic inhibitors of InhA enzyme 108
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 107
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 106
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 106
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 106
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 104
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 103
New medicines against tuberculosis. 103
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 103
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 103
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 103
Nitric oxide-releasing compounds for the treatment of lung infections 100
Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis. 99
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 99
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 99
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 99
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 99
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 98
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 98
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 96
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 95
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 94
Characterization and heterologous expression of the oxalyl-CoA decarboxylase gene from Bifidobacterium lactis 94
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options 91
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 91
Molecular basis for antibiotic resistance in the genus Burkholderia 91
Iron acquisition pathways as targets for antitubercular drugs. 91
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 89
Totale 12.638
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Categoria #
all - tutte 56.916
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.916
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022527 0 0 0 0 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/20251.990 44 135 65 53 94 164 91 116 506 71 230 421
2025/20264.597 369 256 533 450 619 223 867 200 435 355 163 127
2026/20271.335 72 237 313 505 208 0 0 0 0 0 0 0
Totale 14.204