IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.289
AS - Asia 3.705
EU - Europa 3.165
SA - Sud America 490
Continente sconosciuto - Info sul continente non disponibili 318
AF - Africa 160
OC - Oceania 13
AN - Antartide 1
Totale 13.141
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Nazione #
US - Stati Uniti d'America 5.128
CN - Cina 1.725
SG - Singapore 797
IE - Irlanda 705
HK - Hong Kong 389
RU - Federazione Russa 371
DE - Germania 368
BR - Brasile 361
IT - Italia 341
VN - Vietnam 341
FI - Finlandia 328
UA - Ucraina 328
FR - Francia 180
SE - Svezia 166
GB - Regno Unito 158
IN - India 106
ZA - Sudafrica 103
CA - Canada 91
BD - Bangladesh 58
JP - Giappone 49
MX - Messico 38
IQ - Iraq 35
ES - Italia 34
AR - Argentina 33
PL - Polonia 32
TR - Turchia 31
AT - Austria 29
CO - Colombia 24
NL - Olanda 24
BE - Belgio 23
EC - Ecuador 19
ID - Indonesia 19
VE - Venezuela 18
PK - Pakistan 16
CZ - Repubblica Ceca 14
SA - Arabia Saudita 13
LT - Lituania 12
UZ - Uzbekistan 12
AU - Australia 11
BO - Bolivia 10
CL - Cile 10
MA - Marocco 10
MY - Malesia 10
PH - Filippine 10
AZ - Azerbaigian 8
JO - Giordania 8
KE - Kenya 8
KR - Corea 8
PE - Perù 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
CR - Costa Rica 7
HU - Ungheria 7
TN - Tunisia 7
EG - Egitto 6
KG - Kirghizistan 6
KZ - Kazakistan 6
OM - Oman 6
CH - Svizzera 5
GR - Grecia 5
GT - Guatemala 5
IL - Israele 5
JM - Giamaica 5
PY - Paraguay 5
RS - Serbia 5
TH - Thailandia 5
DK - Danimarca 4
LV - Lettonia 4
NG - Nigeria 4
PA - Panama 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
HR - Croazia 3
LB - Libano 3
NI - Nicaragua 3
NP - Nepal 3
PS - Palestinian Territory 3
AL - Albania 2
AM - Armenia 2
CG - Congo 2
DZ - Algeria 2
ET - Etiopia 2
GA - Gabon 2
LK - Sri Lanka 2
MU - Mauritius 2
NA - Namibia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
RE - Reunion 2
RO - Romania 2
UY - Uruguay 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
Totale 12.802
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Città #
Dublin 705
Chandler 672
San Jose 520
Ashburn 504
Singapore 453
Jacksonville 428
Beijing 382
Hong Kong 374
Dallas 319
Nanjing 310
Boardman 208
Council Bluffs 187
Los Angeles 137
Helsinki 132
Pavia 125
Ho Chi Minh City 124
Nanchang 120
Wilmington 110
Princeton 106
Medford 103
Lauterbourg 102
Lawrence 102
New York 96
Ann Arbor 93
Munich 93
Shenyang 93
Changsha 91
Johannesburg 87
Jiaxing 79
Hebei 76
Hanoi 75
Shanghai 68
Santa Clara 60
Tianjin 60
Hangzhou 56
Moscow 53
Buffalo 52
Tokyo 48
Milan 42
Redondo Beach 40
Orem 35
Turku 35
Woodbridge 32
Warsaw 30
The Dalles 28
Ottawa 27
San Francisco 26
São Paulo 25
Columbus 24
Frankfurt am Main 24
Vienna 24
Chicago 23
Montreal 23
Stockholm 22
Piscataway 21
Brooklyn 20
Brussels 20
Falkenstein 20
Chennai 19
Da Nang 18
London 18
Toronto 18
Verona 17
Denver 16
Guangzhou 16
Norwalk 16
Haiphong 15
Phoenix 15
Seattle 15
Houston 14
Mexico City 14
Boston 13
Dearborn 13
Mumbai 13
Amsterdam 12
Olomouc 12
Atlanta 11
Baghdad 11
Brasília 11
Fairfield 11
Nuremberg 11
Paris 11
Rome 11
San Genesio ed Uniti 11
Falls Church 10
Istanbul 10
Tashkent 10
Belo Horizonte 9
Biên Hòa 9
Madrid 9
Manchester 9
New Delhi 9
Poplar 9
Porto Alegre 9
Pune 9
Washington 9
Amman 8
Chongqing 8
Jinan 8
Baku 7
Totale 8.448
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 209
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 181
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 168
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 167
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 161
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 160
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 154
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 153
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 153
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 152
A census of RND superfamily proteins in the Burkholderia genus. 151
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 150
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 147
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 147
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 146
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 144
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 144
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 143
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 141
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 139
MmpL3 is the cellular target of the antitubercular drug BM212. 139
Identification of cellular targets of new antitubercular drugs. 135
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 133
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 133
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 132
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 131
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 131
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 131
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 129
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 129
Azole drug resistance in Mycobacterium tuberculosis 128
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 128
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 128
New prodrugs against tuberculosis 128
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 126
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 126
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 125
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 125
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 125
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 123
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 123
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 121
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 121
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 120
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 119
New and old hot drug targets in tuberculosis 119
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 117
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 117
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 117
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 116
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 114
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 113
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 112
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 112
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 112
Mycobacterium tuberculosis: drug resistance and future perspectives 112
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 112
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 112
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 111
DprE1, a new taxonomic marker in mycobacteria. 111
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 111
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 109
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 109
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 109
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 109
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 108
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 106
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 104
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 104
First triclosan-based macrocyclic inhibitors of InhA enzyme 104
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 102
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 101
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 100
Mycobacterium tuberculosis Sulfate Ester Dioxygenase Rv3406 Is Able to Inactivate the RCB18350 Compound. 98
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 97
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 96
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 96
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 96
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 95
Nitric oxide-releasing compounds for the treatment of lung infections 95
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 94
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 94
New medicines against tuberculosis. 94
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 94
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 94
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 92
Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis. 90
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 90
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 90
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 90
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 88
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 88
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 87
Molecular basis for antibiotic resistance in the genus Burkholderia 87
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 86
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 85
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 83
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options 82
Iron acquisition pathways as targets for antitubercular drugs. 82
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053. 80
Totale 11.825
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Categoria #
all - tutte 52.393
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.393
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022542 0 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/20251.990 44 135 65 53 94 164 91 116 506 71 230 421
2025/20264.597 369 256 533 450 619 223 867 200 435 355 163 127
2026/2027272 72 200 0 0 0 0 0 0 0 0 0 0
Totale 13.141