IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 2.838
EU - Europa 2.101
AS - Asia 1.221
OC - Oceania 8
SA - Sud America 8
AF - Africa 1
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.179
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Nazione #
US - Stati Uniti d'America 2.799
CN - Cina 1.151
IE - Irlanda 699
UA - Ucraina 322
FI - Finlandia 274
IT - Italia 246
DE - Germania 217
SE - Svezia 144
GB - Regno Unito 86
CA - Canada 36
FR - Francia 33
SG - Singapore 33
BE - Belgio 22
AT - Austria 18
RU - Federazione Russa 13
IN - India 10
AU - Australia 8
TR - Turchia 8
ES - Italia 7
CZ - Repubblica Ceca 6
NL - Olanda 4
BR - Brasile 3
CL - Cile 3
MX - Messico 3
ID - Indonesia 2
JP - Giappone 2
PE - Perù 2
PK - Pakistan 2
RO - Romania 2
RS - Serbia 2
SA - Arabia Saudita 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BY - Bielorussia 1
DK - Danimarca 1
EU - Europa 1
GR - Grecia 1
GS - Georgia del Sud e Isole Sandwich Australi 1
HK - Hong Kong 1
HU - Ungheria 1
IR - Iran 1
JO - Giordania 1
KR - Corea 1
MU - Mauritius 1
MY - Malesia 1
TH - Thailandia 1
Totale 6.179
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Città #
Dublin 699
Chandler 671
Jacksonville 425
Nanjing 283
Ashburn 229
Boardman 187
Beijing 183
Nanchang 120
Helsinki 113
Pavia 110
Wilmington 109
Princeton 106
Medford 103
Lawrence 102
Ann Arbor 93
Shenyang 91
Changsha 85
Jiaxing 78
Hebei 76
Shanghai 61
Tianjin 58
Hangzhou 54
New York 42
Woodbridge 31
Milan 28
Ottawa 25
Singapore 23
Los Angeles 21
Brussels 19
Piscataway 18
Verona 17
Norwalk 16
Vienna 16
Dearborn 13
San Francisco 12
San Genesio ed Uniti 11
Fairfield 10
Falls Church 10
Seattle 10
Toronto 10
Washington 8
Chicago 7
Falkenstein 7
Houston 7
Cinisello Balsamo 6
Ningbo 6
Olomouc 6
Taizhou 6
Auburn Hills 5
Guangzhou 5
Gunzenhausen 5
Jinan 5
Madrid 5
Pune 5
Rome 5
Dallas 4
Des Moines 4
Kunming 4
Melbourne 4
Achel 3
Changchun 3
Fiorano Modenese 3
Fuzhou 3
Kemerovo 3
Lanzhou 3
Marcallo Con Casone 3
Munich 3
North Bergen 3
Redwood City 3
Saint Petersburg 3
Zhengzhou 3
Amsterdam 2
Berlin 2
Borås 2
Brookline 2
Como 2
Florence 2
Gallarate 2
Las Vegas 2
Lille 2
Lima 2
Prato 2
Riyadh 2
Rockville 2
San Martino in Strada 2
Sassari 2
Shimla 2
Tappahannock 2
Tokyo 2
West Jordan 2
Albuzzano 1
Aleksinac 1
Amman 1
Bangkok 1
Belgrade 1
Bologna 1
Bratislava 1
Brisbane 1
Canberra 1
Chang-hua 1
Totale 4.556
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 111
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 85
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 84
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 84
MmpL3 is the cellular target of the antitubercular drug BM212. 83
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 83
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 83
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 82
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 81
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 80
Identification of cellular targets of new antitubercular drugs. 79
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 78
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 77
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 77
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 77
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 76
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 75
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 75
A census of RND superfamily proteins in the Burkholderia genus. 75
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 74
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 74
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 74
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 72
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 72
Azole drug resistance in Mycobacterium tuberculosis 71
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 71
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 71
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 71
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 70
Mycobacterium tuberculosis: drug resistance and future perspectives 70
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 69
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 69
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 69
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 69
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 68
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 68
New prodrugs against tuberculosis 68
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 68
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 67
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 67
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 67
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 66
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 66
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 66
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 65
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 65
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 65
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 63
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 63
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 62
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 62
New and old hot drug targets in tuberculosis 62
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 62
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 61
Molecular basis for antibiotic resistance in the genus Burkholderia 61
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 61
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 60
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 58
New medicines against tuberculosis. 58
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 57
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 56
DprE1, a new taxonomic marker in mycobacteria. 56
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 55
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053. 55
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 54
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 54
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 53
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 53
Caratterizzazione genetica e molecolare di un nuovo promotore nel gene hisG di S. typhimurium e ricerca di nuovi elementi coinvolti nella terminazione Rho-dipendente. 52
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 52
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 51
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 50
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 50
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 50
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 50
Suppression of transcriptional polarity by transcription or translation reinitiation in the histidine operon of Salmonella. 49
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 49
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 49
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 48
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 48
Iron acquisition pathways as targets for antitubercular drugs. 47
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 46
In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates. 46
Trends in discovery of new drugs for tuberculosis therapy 45
Characterization and heterologous expression of the oxalyl-CoA decarboxylase gene from Bifidobacterium lactis 44
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 44
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 44
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 43
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 43
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 43
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 43
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 42
Mycobacterium tuberculosis efflux pumps: an update 41
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 39
Nitric oxide-releasing compounds for the treatment of lung infections 39
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 39
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 39
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients. 38
The role of RND efflux transporters in Burkholderia cenocepacia life. 34
First triclosan-based macrocyclic inhibitors of InhA enzyme 33
Totale 6.133
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Categoria #
all - tutte 22.940
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.940
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.076 0 501 7 65 10 71 14 120 15 125 140 8
2020/2021763 106 60 20 66 21 82 18 140 41 98 90 21
2021/2022558 16 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/2025175 44 131 0 0 0 0 0 0 0 0 0 0
Totale 6.457