IRIS
PASCA, MARIA ROSALIA
 Distribuzione geografica
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Continente #
NA - Nord America 2.874
EU - Europa 2.165
AS - Asia 1.470
SA - Sud America 27
OC - Oceania 8
AF - Africa 3
AN - Antartide 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.549
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Nazione #
US - Stati Uniti d'America 2.832
CN - Cina 1.231
IE - Irlanda 699
UA - Ucraina 322
FI - Finlandia 287
IT - Italia 265
DE - Germania 237
SG - Singapore 185
SE - Svezia 144
GB - Regno Unito 93
CA - Canada 38
FR - Francia 33
BE - Belgio 23
BR - Brasile 19
AT - Austria 18
RU - Federazione Russa 14
IN - India 12
AU - Australia 8
TR - Turchia 8
ES - Italia 7
CZ - Repubblica Ceca 6
NL - Olanda 5
CL - Cile 3
JP - Giappone 3
MX - Messico 3
TH - Thailandia 3
AE - Emirati Arabi Uniti 2
BD - Bangladesh 2
ID - Indonesia 2
IL - Israele 2
IQ - Iraq 2
JO - Giordania 2
PE - Perù 2
PK - Pakistan 2
RO - Romania 2
RS - Serbia 2
SA - Arabia Saudita 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
AZ - Azerbaigian 1
BH - Bahrain 1
BY - Bielorussia 1
CH - Svizzera 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
EC - Ecuador 1
EG - Egitto 1
EU - Europa 1
GR - Grecia 1
GS - Georgia del Sud e Isole Sandwich Australi 1
HK - Hong Kong 1
HU - Ungheria 1
IR - Iran 1
KG - Kirghizistan 1
KR - Corea 1
KZ - Kazakistan 1
LT - Lituania 1
MU - Mauritius 1
MY - Malesia 1
PA - Panama 1
PY - Paraguay 1
VE - Venezuela 1
Totale 6.549
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Città #
Dublin 699
Chandler 671
Jacksonville 425
Nanjing 310
Ashburn 232
Beijing 191
Boardman 187
Singapore 140
Helsinki 126
Nanchang 120
Pavia 119
Wilmington 109
Princeton 106
Medford 103
Lawrence 102
Ann Arbor 93
Shenyang 93
Changsha 85
Jiaxing 78
Hebei 76
Shanghai 64
Tianjin 58
Hangzhou 54
New York 42
Woodbridge 31
Milan 28
Ottawa 27
Los Angeles 23
Brussels 20
Piscataway 18
Verona 17
Norwalk 16
Vienna 16
Munich 15
Dearborn 13
Falkenstein 13
San Francisco 13
San Genesio ed Uniti 11
Fairfield 10
Falls Church 10
Seattle 10
Toronto 10
Guangzhou 8
Washington 8
Chicago 7
Chongqing 7
Houston 7
Cinisello Balsamo 6
Jinan 6
Ningbo 6
Olomouc 6
Taizhou 6
Auburn Hills 5
Gunzenhausen 5
Madrid 5
Pune 5
Rome 5
Changchun 4
Dallas 4
Des Moines 4
Kunming 4
Lanzhou 4
London 4
Melbourne 4
Zhengzhou 4
Achel 3
Bangkok 3
Fiorano Modenese 3
Fuzhou 3
Kemerovo 3
Marcallo Con Casone 3
North Bergen 3
Redwood City 3
Saint Petersburg 3
Tokyo 3
Turin 3
Ahmedabad 2
Amman 2
Amsterdam 2
Berlin 2
Birmingham 2
Bologna 2
Borås 2
Brookline 2
Como 2
Florence 2
Frankfurt am Main 2
Gallarate 2
Las Vegas 2
Lille 2
Lima 2
Newark 2
Phoenix 2
Prato 2
Riyadh 2
Rockville 2
San Martino in Strada 2
Sassari 2
Shimla 2
São Paulo 2
Totale 4.789
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Nome #
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. 115
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. 99
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 90
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 88
Decaprenylphosphoryl-β-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target 87
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 87
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 87
MmpL3 is the cellular target of the antitubercular drug BM212. 86
Identificazione e caratterizzazione di pompe di efflusso in Mycobacterium tuberculosis 85
Differential role of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells 84
Identification of cellular targets of new antitubercular drugs. 83
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS 83
A census of RND superfamily proteins in the Burkholderia genus. 83
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias 83
Isolation and characterization of M. tuberculosis and M. bovis BCG mutants resistant to new antitubercular pyrrole derivatives. 81
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 80
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon 79
Rv2686c-2687c-2688c, an ABC fluoroquinolone efflux pump from Mycobacterium tuberculosis 79
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 78
Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 77
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 77
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 76
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità trascrizionale nel gene hisG di Salmonella typhimurium e identificazione di un terminatore della trascrizione nel gene hisC. 76
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. 76
Azole drug resistance in Mycobacterium tuberculosis 75
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis 75
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 75
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. 74
LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis. 73
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis. 73
Espressione, purificazione ed analisi funzionale della NAD+ sintetasi di Mycobacterium tuberculosis, un enzima essenziale 72
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 72
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. 71
Mycobacterium tuberculosis: drug resistance and future perspectives 71
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 70
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents. 70
New prodrugs against tuberculosis 70
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis 70
Mecanismo accion y sensibilidad a inhibidores de la bomba de eflujo Tap de Mycobacterium fortuitum. 69
Identificazione di nuovi “Drug targets”: caratterizzazione di enzimi coinvolti nella biosintesi e nel riciclo del NAD in Mycobacterium tuberculosis 69
Caratterizzazione genetica e molecolare di mutanti che eliminano la polarità nell’operone his di Salmonella typhimurium e ipotesi di azione di nuovi fattori coinvolti nella terminazione rho-dipendente 69
Identification and characterization of the cellular target for benzothiazinones, a new potential antitubercular drug class. 69
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients 69
The mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis. 68
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. 68
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 67
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 67
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia. 67
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 67
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. 67
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 66
Polarità trascrizionale nel gene hisC di Salmonella: caratterizzazione molecolare di mutazioni che sopprimono la polarità. 64
New and old hot drug targets in tuberculosis 64
Role in benzothiazinone resistance of nitroreductase NfnB of Mycobacterium smegmatis 62
Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods 62
Fighting against resistant strains: the case of benzothiazinones and dinitrobenzamides 62
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi 61
New medicines against tuberculosis. 61
Molecular basis for antibiotic resistance in the genus Burkholderia 61
Strategie di isolamento e caratterizzazione di mutanti nella Terminazione Rho-dipendente nell’operone dell’istidina di Salmonella 59
Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. 59
DprE1, a new taxonomic marker in mycobacteria. 58
Rv3790 is the cellular target for benzothiazinones, a new promising antitubercular drug class 58
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis 57
Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia. 56
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents 55
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053. 55
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 55
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis. 54
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis 54
Caratterizzazione genetica e molecolare di un nuovo promotore nel gene hisG di S. typhimurium e ricerca di nuovi elementi coinvolti nella terminazione Rho-dipendente. 53
The role of RND efflux transporters in intrinsic antibiotic resistance of Burkholderia cenocepacia 53
Study of antibiotic efflux pumps belonging to Resistance-Nodulation-Division (RND) family in Burkholderia cenocepacia. 53
Structural genomics and new drug target identification: characterization of enzymes involved in NAD+ biosynthesis and recycling in Mycobacterium tuberculosis. 53
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. 53
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. 53
Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems. 52
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. 52
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis. 51
Suppression of transcriptional polarity by transcription or translation reinitiation in the histidine operon of Salmonella. 50
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities 50
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. 49
In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates. 49
Iron acquisition pathways as targets for antitubercular drugs. 48
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug 48
Trends in discovery of new drugs for tuberculosis therapy 47
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 47
Exploring the HME and HAE1 efflux systems in the genus Burkholderia 46
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis 45
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 45
Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain. 45
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. 45
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 45
Characterization and heterologous expression of the oxalyl-CoA decarboxylase gene from Bifidobacterium lactis 44
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 44
Mycobacterium tuberculosis efflux pumps: an update 43
Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa MDR clinical isolates. 43
Nitric oxide-releasing compounds for the treatment of lung infections 43
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients. 38
Gut Microbial Signatures in Sporadic and Hereditary Colorectal Cancer 37
Totale 6.453
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Categoria #
all - tutte 27.592
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.592
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020422 0 0 0 0 0 0 14 120 15 125 140 8
2020/2021763 106 60 20 66 21 82 18 140 41 98 90 21
2021/2022558 16 6 6 3 14 18 13 25 35 14 76 332
2022/20231.885 170 172 19 155 179 197 0 101 814 12 48 18
2023/2024803 98 161 18 50 61 152 14 108 5 46 52 38
2024/2025560 44 135 65 53 94 164 5 0 0 0 0 0
Totale 6.842