IRIS
LINCIANO, PASQUALE
 Distribuzione geografica
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Continente #
NA - Nord America 2.118
AS - Asia 1.648
EU - Europa 1.128
SA - Sud America 287
AF - Africa 82
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
AN - Antartide 1
Totale 5.272
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Nazione #
US - Stati Uniti d'America 2.052
CN - Cina 481
SG - Singapore 445
HK - Hong Kong 306
IE - Irlanda 296
BR - Brasile 208
RU - Federazione Russa 203
VN - Vietnam 182
IT - Italia 160
DE - Germania 103
FR - Francia 95
FI - Finlandia 70
GB - Regno Unito 66
IN - India 48
ZA - Sudafrica 46
BD - Bangladesh 31
AR - Argentina 28
CA - Canada 27
PL - Polonia 25
IQ - Iraq 23
JP - Giappone 23
AT - Austria 22
MX - Messico 22
ES - Italia 16
EC - Ecuador 15
VE - Venezuela 15
SE - Svezia 13
ID - Indonesia 12
BE - Belgio 11
TR - Turchia 11
NL - Olanda 10
PK - Pakistan 10
MA - Marocco 9
CO - Colombia 8
PH - Filippine 8
SA - Arabia Saudita 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
UA - Ucraina 7
JO - Giordania 6
CZ - Repubblica Ceca 5
EU - Europa 5
KR - Corea 5
LT - Lituania 5
TW - Taiwan 5
BO - Bolivia 4
CL - Cile 4
DO - Repubblica Dominicana 4
EG - Egitto 4
JM - Giamaica 4
KZ - Kazakistan 4
OM - Oman 4
SN - Senegal 4
TN - Tunisia 4
AZ - Azerbaigian 3
DZ - Algeria 3
HU - Ungheria 3
KE - Kenya 3
MY - Malesia 3
PA - Panama 3
PE - Perù 3
SI - Slovenia 3
AL - Albania 2
BG - Bulgaria 2
GA - Gabon 2
IL - Israele 2
KG - Kirghizistan 2
LB - Libano 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
PT - Portogallo 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
AQ - Antartide 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CY - Cipro 1
DK - Danimarca 1
ET - Etiopia 1
HN - Honduras 1
HR - Croazia 1
KW - Kuwait 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LV - Lettonia 1
ME - Montenegro 1
ML - Mali 1
NA - Namibia 1
NO - Norvegia 1
NP - Nepal 1
PY - Paraguay 1
QA - Qatar 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
Totale 5.269
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Città #
Hong Kong 298
Dublin 295
San Jose 269
Ashburn 259
Chandler 257
Dallas 250
Singapore 233
Beijing 125
Boardman 81
Lauterbourg 76
Los Angeles 70
Shanghai 67
Helsinki 59
Ho Chi Minh City 58
Hanoi 50
New York 49
Munich 45
Johannesburg 37
Buffalo 35
Redondo Beach 33
Pavia 32
Moscow 29
The Dalles 29
Orem 26
Seattle 24
Lawrence 23
Medford 23
Princeton 23
Tokyo 23
Warsaw 23
Santa Clara 22
Florence 18
Council Bluffs 17
Milan 17
Wilmington 16
São Paulo 15
Columbus 14
Frankfurt am Main 14
Vienna 14
Chicago 13
Washington 13
Atlanta 12
Da Nang 12
Stockholm 12
Brussels 11
Chennai 11
Nanjing 11
Baghdad 10
Mexico City 10
New Delhi 10
Turku 10
Montreal 9
Motta di Livenza 9
Boston 8
Dhaka 8
Tashkent 8
Brooklyn 7
Denver 7
Manchester 7
Nuremberg 7
Quito 7
Amman 6
Amsterdam 6
Brasília 6
Curitiba 6
Falkenstein 6
Guangzhou 6
London 6
Palermo 6
Phoenix 6
Poplar 6
San Francisco 6
Toronto 6
Ankara 5
Bari 5
Bolzaneto 5
Buenos Aires 5
Düsseldorf 5
Haiphong 5
Pune 5
Seoul 5
Woodbridge 5
Biên Hòa 4
Cairo 4
Caracas 4
Changsha 4
Chongqing 4
Dakar 4
Dubai 4
Houston 4
Kingston 4
Kyiv 4
Lahore 4
Lucknow 4
Muscat 4
Ninh Bình 4
Paris 4
Pretoria 4
Rio de Janeiro 4
Ann Arbor 3
Totale 3.448
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Nome #
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 121
COMPOSTI AD ATTIVITÀ ANTIPARASSITARIA 114
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 109
Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells 106
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 106
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 101
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 99
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 98
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 97
EFFECTS OF ENDOCRINE ACTIVE CONTAMINATING PESTICIDES ON RACK1 EXPRESSION AND IMMUNOLOGICAL CONSEQUENCES IN THP-1 CELLS 94
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 94
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 91
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents 84
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 84
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases 82
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates 79
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain 79
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases 78
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers 78
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R) 78
Cannabinoid profiling of hemp seed oil by liquid chromatography coupled to high-resolution mass spectrometry 78
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 77
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections 77
Analysis of impurities of cannabidiol from hemp. Isolation, characterization and synthesis of cannabidibutol, the novel cannabidiol butyl analog 77
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 76
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities 76
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells 75
Investigation of the effect of different linker chemotypes on the inhibition of Histone Deacetylases (HDACs) 75
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 74
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 74
Neurodegeneration: can metabolites from Eremurus persicus help? 73
Chemical and spectroscopic characterization data of ‘cannabidibutol’, a novel cannabidiol butyl analog 72
A multidisciplinary approach to the design of novel inhibitors for KPC-2 71
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview 69
Sigma-1 receptor agonists acting on aquaporin-mediated h2o2 permeability: New tools for counteracting oxidative stress 69
A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol 68
Druggability profile of stilbene-derived PPAR agonists: Determination of physicochemical properties and PAMPA study 68
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 67
Development of therapeutic agents blocking SOS activation 67
The novel heptyl phorolic acid cannabinoids content in different Cannabis sativa L. accessions 65
New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation 62
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era 61
Evolving Challenges and Opportunities in Plant-based Drug Discovery and Development 61
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 59
Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase 59
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer 59
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes 58
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents 57
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics 57
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 57
Ten Years with New Delhi Metallo-β-lactamase-1 (NDM-1): From Structural Insights to Inhibitor Design 57
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization 56
Is cannabidiol a scheduled controlled substance? Origin makes the difference 56
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation 55
Discovery of semisynthetic derivatives of (R)- and (S)-usnic acids as potential antifungal agents against C. tropicalis and T. rubrum 52
Identification of a novel extracellular inhibitor of FGF2/FGFR signaling axis by combined virtual screening and NMR spectroscopy approach 52
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 52
Origin of Δ9-Tetrahydrocannabinol Impurity in Synthetic Cannabidiol 52
Effect of stilbene and chalcone scaffolds incorporation in clofibric acid on PPARα agonistic activity 50
Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol 50
New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics
 49
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 49
Geometric Isomerism of an Acetamidino Derivative Determined by NMR Investigations 44
Structural development studies of PPARs ligands based on tyrosine scaffold 42
Urea-based anticancer agents. Exploring 100-years of research with an eye to the future 40
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins 40
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa 39
Phenyl boronic acids development led to validated leads active in clinical strains overexpressing KPC-2: a step against bacterial resistance 39
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase 37
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds 37
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 35
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 34
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol 34
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 34
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs 34
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 34
In Silico-Guided Discovery and In Vitro Evaluation of Natural Sortase A Inhibitors to Fight Multidrug-Resistant Staphylococcus aureus 32
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To InhibitTrypanosoma bruceiPteridine Reductase in Support of Early-Stage Drug Discovery 32
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 31
Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections 28
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents 28
In silico identification and experimental validation of hits active against KPC-2 β-lactamase 27
Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach 26
Phenylboronic Acids Probing Molecular Recognition against Class A and Class C beta-Lactamases 26
Use of primary amines for the selective N-Alkylation of anilines by a reusable heterogeneous catalyst 26
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group 25
Optimization of N-alkylation in the Synthesis of Methotrexate and Pteridine-based Derivatives Under Microwave-Irradiation 24
Totale 5.368
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Categoria #
all - tutte 25.997
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.997
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022120 0 0 16 0 1 3 1 13 2 4 22 58
2022/2023729 33 45 14 65 56 76 0 47 341 9 27 16
2023/2024502 23 92 21 27 34 124 63 40 6 21 22 29
2024/20251.262 22 92 20 24 33 118 84 60 310 60 142 297
2025/20262.723 238 247 337 305 363 100 529 149 278 177 0 0
Totale 5.368