IRIS
LINCIANO, PASQUALE
 Distribuzione geografica
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Continente #
NA - Nord America 3.428
AS - Asia 1.779
EU - Europa 1.461
SA - Sud America 297
Continente sconosciuto - Info sul continente non disponibili 108
AF - Africa 88
OC - Oceania 3
AN - Antartide 1
Totale 7.165
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Nazione #
US - Stati Uniti d'America 3.260
CN - Cina 526
SG - Singapore 473
IT - Italia 448
HK - Hong Kong 315
IE - Irlanda 297
RU - Federazione Russa 212
BR - Brasile 211
VN - Vietnam 185
DE - Germania 110
FR - Francia 99
GB - Regno Unito 76
FI - Finlandia 71
CA - Canada 66
BD - Bangladesh 59
IN - India 50
ZA - Sudafrica 46
AR - Argentina 29
PL - Polonia 26
MX - Messico 24
IQ - Iraq 23
JP - Giappone 23
AT - Austria 22
EC - Ecuador 17
ES - Italia 16
NL - Olanda 16
VE - Venezuela 16
ID - Indonesia 15
SE - Svezia 13
CR - Costa Rica 12
BE - Belgio 11
CO - Colombia 11
JM - Giamaica 11
PK - Pakistan 11
TR - Turchia 11
HN - Honduras 10
MA - Marocco 9
PH - Filippine 9
IL - Israele 8
SA - Arabia Saudita 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
SV - El Salvador 7
TT - Trinidad e Tobago 7
UA - Ucraina 7
JO - Giordania 6
NI - Nicaragua 6
CZ - Repubblica Ceca 5
EU - Europa 5
GT - Guatemala 5
KR - Corea 5
KZ - Kazakistan 5
LT - Lituania 5
MY - Malesia 5
TW - Taiwan 5
BO - Bolivia 4
CL - Cile 4
DO - Repubblica Dominicana 4
EG - Egitto 4
GP - Guadalupe 4
OM - Oman 4
PR - Porto Rico 4
SC - Seychelles 4
SN - Senegal 4
TN - Tunisia 4
AZ - Azerbaigian 3
DK - Danimarca 3
DZ - Algeria 3
EE - Estonia 3
HU - Ungheria 3
KE - Kenya 3
NP - Nepal 3
PA - Panama 3
PE - Perù 3
SI - Slovenia 3
AL - Albania 2
BG - Bulgaria 2
BM - Bermuda 2
ET - Etiopia 2
GA - Gabon 2
KG - Kirghizistan 2
LB - Libano 2
LC - Santa Lucia 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
PT - Portogallo 2
AM - Armenia 1
AO - Angola 1
AQ - Antartide 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BJ - Benin 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
CY - Cipro 1
HR - Croazia 1
KW - Kuwait 1
Totale 7.049
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Città #
San Jose 473
Hong Kong 306
Ashburn 301
Dublin 295
Council Bluffs 277
Dallas 261
Chandler 257
Singapore 242
Beijing 138
Los Angeles 85
Boardman 83
Lauterbourg 76
Shanghai 68
Milan 66
New York 63
Helsinki 59
Ho Chi Minh City 58
Santa Clara 57
Hanoi 51
Munich 45
Buffalo 42
Columbus 42
Johannesburg 37
Pavia 34
Redondo Beach 33
Orem 30
Florence 29
Moscow 29
Rome 29
The Dalles 29
Seattle 25
Lawrence 23
Medford 23
Princeton 23
Tokyo 23
Warsaw 23
Atlanta 21
Phoenix 21
Chicago 19
Naples 18
Wilmington 18
Frankfurt am Main 15
São Paulo 15
Washington 15
Brooklyn 14
Vienna 14
Figino 13
North Bergen 13
Da Nang 12
Nanjing 12
Palermo 12
San Francisco 12
Stockholm 12
Toronto 12
Brussels 11
Chennai 11
Mexico City 11
Montreal 11
Turku 11
Baghdad 10
Kingston 10
New Delhi 10
Bari 9
Bologna 9
Denver 9
Motta di Livenza 9
Turin 9
Boston 8
Brasília 8
Dhaka 8
Tashkent 8
Guangzhou 7
Manchester 7
Nuremberg 7
Quito 7
Amman 6
Amsterdam 6
Curitiba 6
Falkenstein 6
London 6
Managua 6
Poplar 6
Ankara 5
Bolzaneto 5
Buenos Aires 5
Catania 5
Düsseldorf 5
Haiphong 5
Houston 5
Newark 5
Pune 5
San Pedro Sula 5
San Salvador 5
Seoul 5
Verona 5
Woodbridge 5
Biên Hòa 4
Cairo 4
Caracas 4
Changsha 4
Totale 4.321
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Nome #
Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells 214
Plasminogen Recruitment by Staphylococcus aureus SdrC Reveals a Tractable Antivirulence Target 153
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 133
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 129
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 126
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 124
COMPOSTI AD ATTIVITÀ ANTIPARASSITARIA 124
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 124
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates 116
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 116
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 111
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 110
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents 106
EFFECTS OF ENDOCRINE ACTIVE CONTAMINATING PESTICIDES ON RACK1 EXPRESSION AND IMMUNOLOGICAL CONSEQUENCES IN THP-1 CELLS 106
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 106
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 104
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers 103
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells 100
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases 99
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases 97
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 97
Neurodegeneration: can metabolites from Eremurus persicus help? 96
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 95
Analysis of impurities of cannabidiol from hemp. Isolation, characterization and synthesis of cannabidibutol, the novel cannabidiol butyl analog 93
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R) 93
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 92
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities 92
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections 91
Cannabinoid profiling of hemp seed oil by liquid chromatography coupled to high-resolution mass spectrometry 91
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation 90
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 89
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain 88
Investigation of the effect of different linker chemotypes on the inhibition of Histone Deacetylases (HDACs) 88
Sigma-1 receptor agonists acting on aquaporin-mediated h2o2 permeability: New tools for counteracting oxidative stress 88
New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation 88
A multidisciplinary approach to the design of novel inhibitors for KPC-2 86
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview 86
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 84
Chemical and spectroscopic characterization data of ‘cannabidibutol’, a novel cannabidiol butyl analog 84
Druggability profile of stilbene-derived PPAR agonists: Determination of physicochemical properties and PAMPA study 84
The novel heptyl phorolic acid cannabinoids content in different Cannabis sativa L. accessions 84
A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol 81
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes 80
Development of therapeutic agents blocking SOS activation 78
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents 77
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization 76
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics 76
Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase 76
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era 75
Evolving Challenges and Opportunities in Plant-based Drug Discovery and Development 75
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 74
Ten Years with New Delhi Metallo-β-lactamase-1 (NDM-1): From Structural Insights to Inhibitor Design 73
Identification of a novel extracellular inhibitor of FGF2/FGFR signaling axis by combined virtual screening and NMR spectroscopy approach 69
Is cannabidiol a scheduled controlled substance? Origin makes the difference 69
Discovery of semisynthetic derivatives of (R)- and (S)-usnic acids as potential antifungal agents against C. tropicalis and T. rubrum 68
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 68
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer 67
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 66
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 66
Effect of stilbene and chalcone scaffolds incorporation in clofibric acid on PPARα agonistic activity 63
New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics
 62
Origin of Δ9-Tetrahydrocannabinol Impurity in Synthetic Cannabidiol 62
Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol 61
Targeting Autoinducer-2 Quorum Sensing: Novel Inhibitors Attenuate Virulence in Staphylococcus aureus and Pseudomonas aeruginosa 58
Phenyl boronic acids development led to validated leads active in clinical strains overexpressing KPC-2: a step against bacterial resistance 57
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 56
Geometric Isomerism of an Acetamidino Derivative Determined by NMR Investigations 54
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 53
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa 52
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds 51
In Silico-Guided Discovery and In Vitro Evaluation of Natural Sortase A Inhibitors to Fight Multidrug-Resistant Staphylococcus aureus 50
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 50
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase 50
Structural development studies of PPARs ligands based on tyrosine scaffold 50
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins 49
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents 49
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol 48
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs 47
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 47
Urea-based anticancer agents. Exploring 100-years of research with an eye to the future 47
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 44
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To InhibitTrypanosoma bruceiPteridine Reductase in Support of Early-Stage Drug Discovery 44
Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections 42
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group 41
Phenylboronic Acids Probing Molecular Recognition against Class A and Class C beta-Lactamases 40
In silico identification and experimental validation of hits active against KPC-2 β-lactamase 37
Use of primary amines for the selective N-Alkylation of anilines by a reusable heterogeneous catalyst 36
Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach 35
Optimization of N-alkylation in the Synthesis of Methotrexate and Pteridine-based Derivatives Under Microwave-Irradiation 35
Sustainable chemistry and preclinical characterization of RC-106·HCl: A brain-penetrant pan sigma receptor modulator for glioblastoma 26
HuR-Targeted Small Molecules Reduce Pseudomonas aeruginosa Adhesion in Cystic Fibrosis Airway Epithelial Cells 26
Bioprospecting Italian biodiversity for identifying potential neuroprotective agents 26
The Differential Redox Resilience of Alvelestat and Sivelestat: A Mechanistic Hypothesis for Inhibitor Performance Under Oxidative Stress 23
Totale 7.165
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Categoria #
all - tutte 34.415
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.415
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022104 0 0 0 0 1 3 1 13 2 4 22 58
2022/2023729 33 45 14 65 56 76 0 47 341 9 27 16
2023/2024502 23 92 21 27 34 124 63 40 6 21 22 29
2024/20251.262 22 92 20 24 33 118 84 60 310 60 142 297
2025/20263.103 238 247 337 305 363 100 529 149 278 235 166 156
2026/20271.417 169 383 178 445 242 0 0 0 0 0 0 0
Totale 7.165