IRIS
LINCIANO, PASQUALE
 Distribuzione geografica
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Continente #
NA - Nord America 2.728
AS - Asia 1.756
EU - Europa 1.232
SA - Sud America 291
Continente sconosciuto - Info sul continente non disponibili 107
AF - Africa 83
OC - Oceania 3
AN - Antartide 1
Totale 6.201
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Nazione #
US - Stati Uniti d'America 2.637
CN - Cina 520
SG - Singapore 470
HK - Hong Kong 315
IE - Irlanda 296
IT - Italia 259
BR - Brasile 209
RU - Federazione Russa 203
VN - Vietnam 185
DE - Germania 105
FR - Francia 95
FI - Finlandia 70
GB - Regno Unito 67
BD - Bangladesh 57
IN - India 50
ZA - Sudafrica 46
CA - Canada 43
AR - Argentina 28
PL - Polonia 26
MX - Messico 24
IQ - Iraq 23
JP - Giappone 23
AT - Austria 22
EC - Ecuador 16
ES - Italia 16
VE - Venezuela 15
ID - Indonesia 13
SE - Svezia 13
BE - Belgio 11
NL - Olanda 11
TR - Turchia 11
CO - Colombia 10
PK - Pakistan 10
MA - Marocco 9
PH - Filippine 9
SA - Arabia Saudita 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
UA - Ucraina 7
JO - Giordania 6
CZ - Repubblica Ceca 5
EU - Europa 5
JM - Giamaica 5
KR - Corea 5
LT - Lituania 5
TW - Taiwan 5
BO - Bolivia 4
CL - Cile 4
DO - Repubblica Dominicana 4
EG - Egitto 4
KZ - Kazakistan 4
MY - Malesia 4
OM - Oman 4
SN - Senegal 4
TN - Tunisia 4
AZ - Azerbaigian 3
CR - Costa Rica 3
DZ - Algeria 3
HN - Honduras 3
HU - Ungheria 3
KE - Kenya 3
PA - Panama 3
PE - Perù 3
SI - Slovenia 3
AL - Albania 2
BG - Bulgaria 2
ET - Etiopia 2
GA - Gabon 2
IL - Israele 2
KG - Kirghizistan 2
LB - Libano 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
PT - Portogallo 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
AQ - Antartide 1
AU - Australia 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CY - Cipro 1
DK - Danimarca 1
HR - Croazia 1
KW - Kuwait 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LV - Lettonia 1
ME - Montenegro 1
ML - Mali 1
NA - Namibia 1
NI - Nicaragua 1
NO - Norvegia 1
PR - Porto Rico 1
PY - Paraguay 1
QA - Qatar 1
RS - Serbia 1
Totale 6.094
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Città #
San Jose 410
Hong Kong 306
Dublin 295
Ashburn 284
Chandler 257
Dallas 255
Singapore 242
Council Bluffs 152
Beijing 138
Boardman 83
Los Angeles 78
Lauterbourg 76
Shanghai 67
New York 60
Helsinki 59
Ho Chi Minh City 58
Hanoi 51
Milan 45
Munich 45
Santa Clara 42
Buffalo 41
Columbus 38
Johannesburg 37
Pavia 34
Redondo Beach 33
Orem 30
Moscow 29
The Dalles 29
Seattle 25
Lawrence 23
Medford 23
Princeton 23
Tokyo 23
Warsaw 23
Florence 20
Chicago 17
Atlanta 16
Wilmington 16
Frankfurt am Main 15
São Paulo 15
Vienna 14
Washington 14
Figino 13
Rome 13
Da Nang 12
Nanjing 12
San Francisco 12
Stockholm 12
Brussels 11
Chennai 11
Mexico City 11
Montreal 11
Baghdad 10
New Delhi 10
Turku 10
Motta di Livenza 9
Toronto 9
Boston 8
Dhaka 8
Palermo 8
Tashkent 8
Brooklyn 7
Denver 7
Guangzhou 7
Manchester 7
Nuremberg 7
Phoenix 7
Quito 7
Amman 6
Amsterdam 6
Bari 6
Brasília 6
Curitiba 6
Falkenstein 6
London 6
Poplar 6
Ankara 5
Bologna 5
Bolzaneto 5
Buenos Aires 5
Düsseldorf 5
Haiphong 5
Kingston 5
Pune 5
Seoul 5
Woodbridge 5
Biên Hòa 4
Cairo 4
Caracas 4
Changsha 4
Chongqing 4
Dakar 4
Dubai 4
Hangzhou 4
Houston 4
Kyiv 4
Lahore 4
Lucca 4
Lucknow 4
Muscat 4
Totale 3.942
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Nome #
Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells 201
Plasminogen Recruitment by Staphylococcus aureus SdrC Reveals a Tractable Antivirulence Target 133
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 122
COMPOSTI AD ATTIVITÀ ANTIPARASSITARIA 119
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 113
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 113
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 110
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 109
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 103
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 102
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates 99
EFFECTS OF ENDOCRINE ACTIVE CONTAMINATING PESTICIDES ON RACK1 EXPRESSION AND IMMUNOLOGICAL CONSEQUENCES IN THP-1 CELLS 98
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 98
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 96
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 95
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents 93
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases 93
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 88
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections 85
Neurodegeneration: can metabolites from Eremurus persicus help? 84
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain 84
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities 84
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells 83
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers 83
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R) 83
Cannabinoid profiling of hemp seed oil by liquid chromatography coupled to high-resolution mass spectrometry 83
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 82
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases 82
Investigation of the effect of different linker chemotypes on the inhibition of Histone Deacetylases (HDACs) 81
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 80
Analysis of impurities of cannabidiol from hemp. Isolation, characterization and synthesis of cannabidibutol, the novel cannabidiol butyl analog 80
Chemical and spectroscopic characterization data of ‘cannabidibutol’, a novel cannabidiol butyl analog 79
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 78
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 76
Development of therapeutic agents blocking SOS activation 75
Druggability profile of stilbene-derived PPAR agonists: Determination of physicochemical properties and PAMPA study 75
Sigma-1 receptor agonists acting on aquaporin-mediated h2o2 permeability: New tools for counteracting oxidative stress 75
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview 74
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation 74
A multidisciplinary approach to the design of novel inhibitors for KPC-2 73
A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol 71
New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation 71
The novel heptyl phorolic acid cannabinoids content in different Cannabis sativa L. accessions 70
Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase 69
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 67
Evolving Challenges and Opportunities in Plant-based Drug Discovery and Development 67
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes 66
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era 65
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization 64
Is cannabidiol a scheduled controlled substance? Origin makes the difference 64
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics 63
Ten Years with New Delhi Metallo-β-lactamase-1 (NDM-1): From Structural Insights to Inhibitor Design 62
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents 61
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 60
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer 60
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 59
Identification of a novel extracellular inhibitor of FGF2/FGFR signaling axis by combined virtual screening and NMR spectroscopy approach 59
Effect of stilbene and chalcone scaffolds incorporation in clofibric acid on PPARα agonistic activity 57
New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics
 57
Origin of Δ9-Tetrahydrocannabinol Impurity in Synthetic Cannabidiol 56
Discovery of semisynthetic derivatives of (R)- and (S)-usnic acids as potential antifungal agents against C. tropicalis and T. rubrum 55
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 53
Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol 52
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 52
Phenyl boronic acids development led to validated leads active in clinical strains overexpressing KPC-2: a step against bacterial resistance 49
Geometric Isomerism of an Acetamidino Derivative Determined by NMR Investigations 48
Targeting Autoinducer-2 Quorum Sensing: Novel Inhibitors Attenuate Virulence in Staphylococcus aureus and Pseudomonas aeruginosa 47
Structural development studies of PPARs ligands based on tyrosine scaffold 46
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 44
Urea-based anticancer agents. Exploring 100-years of research with an eye to the future 44
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa 44
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds 44
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 43
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins 42
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase 41
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol 39
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs 37
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To InhibitTrypanosoma bruceiPteridine Reductase in Support of Early-Stage Drug Discovery 37
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 36
In Silico-Guided Discovery and In Vitro Evaluation of Natural Sortase A Inhibitors to Fight Multidrug-Resistant Staphylococcus aureus 35
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 35
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group 34
Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections 33
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents 31
In silico identification and experimental validation of hits active against KPC-2 β-lactamase 31
Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach 29
Use of primary amines for the selective N-Alkylation of anilines by a reusable heterogeneous catalyst 29
Phenylboronic Acids Probing Molecular Recognition against Class A and Class C beta-Lactamases 28
Optimization of N-alkylation in the Synthesis of Methotrexate and Pteridine-based Derivatives Under Microwave-Irradiation 28
Sustainable chemistry and preclinical characterization of RC-106·HCl: A brain-penetrant pan sigma receptor modulator for glioblastoma 12
The Differential Redox Resilience of Alvelestat and Sivelestat: A Mechanistic Hypothesis for Inhibitor Performance Under Oxidative Stress 9
HuR-Targeted Small Molecules Reduce Pseudomonas aeruginosa Adhesion in Cystic Fibrosis Airway Epithelial Cells 4
Bioprospecting Italian biodiversity for identifying potential neuroprotective agents 4
Totale 6.201
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Categoria #
all - tutte 30.486
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.486
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022120 0 0 16 0 1 3 1 13 2 4 22 58
2022/2023729 33 45 14 65 56 76 0 47 341 9 27 16
2023/2024502 23 92 21 27 34 124 63 40 6 21 22 29
2024/20251.262 22 92 20 24 33 118 84 60 310 60 142 297
2025/20263.103 238 247 337 305 363 100 529 149 278 235 166 156
2026/2027453 169 284 0 0 0 0 0 0 0 0 0 0
Totale 6.201