IRIS
LINCIANO, PASQUALE
 Distribuzione geografica
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Continente #
NA - Nord America 1.685
AS - Asia 1.214
EU - Europa 967
SA - Sud America 226
AF - Africa 37
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
AN - Antartide 1
Totale 4.138
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Nazione #
US - Stati Uniti d'America 1.633
CN - Cina 405
SG - Singapore 348
IE - Irlanda 296
HK - Hong Kong 259
RU - Federazione Russa 202
BR - Brasile 182
IT - Italia 131
DE - Germania 94
FI - Finlandia 69
VN - Vietnam 68
GB - Regno Unito 55
IN - India 26
CA - Canada 23
PL - Polonia 23
AT - Austria 20
JP - Giappone 20
MX - Messico 19
BD - Bangladesh 17
AR - Argentina 16
ES - Italia 16
SE - Svezia 12
ZA - Sudafrica 12
BE - Belgio 11
FR - Francia 10
IQ - Iraq 10
TR - Turchia 10
EC - Ecuador 9
AE - Emirati Arabi Uniti 7
CO - Colombia 7
VE - Venezuela 7
ID - Indonesia 6
MA - Marocco 6
NL - Olanda 6
EU - Europa 5
KR - Corea 5
LT - Lituania 5
TW - Taiwan 5
UA - Ucraina 5
CZ - Repubblica Ceca 4
KZ - Kazakistan 4
JO - Giordania 3
KE - Kenya 3
PK - Pakistan 3
SN - Senegal 3
TN - Tunisia 3
UZ - Uzbekistan 3
DO - Repubblica Dominicana 2
DZ - Algeria 2
EG - Egitto 2
IL - Israele 2
JM - Giamaica 2
LB - Libano 2
NZ - Nuova Zelanda 2
PE - Perù 2
PH - Filippine 2
SI - Slovenia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AQ - Antartide 1
AU - Australia 1
AZ - Azerbaigian 1
BJ - Benin 1
BO - Bolivia 1
CI - Costa d'Avorio 1
DK - Danimarca 1
GA - Gabon 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LV - Lettonia 1
ME - Montenegro 1
ML - Mali 1
MY - Malesia 1
NA - Namibia 1
NP - Nepal 1
PA - Panama 1
PS - Palestinian Territory 1
PY - Paraguay 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
TH - Thailandia 1
UY - Uruguay 1
ZW - Zimbabwe 1
Totale 4.138
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Città #
Dublin 295
Chandler 257
Hong Kong 253
Dallas 249
Ashburn 213
Singapore 162
Beijing 119
Boardman 81
Shanghai 67
Los Angeles 62
Helsinki 59
New York 48
Munich 45
Buffalo 35
Redondo Beach 33
The Dalles 29
Moscow 28
Pavia 27
Ho Chi Minh City 26
Seattle 24
Lawrence 23
Medford 23
Princeton 23
Warsaw 22
Tokyo 20
Hanoi 19
Wilmington 16
Florence 15
Milan 15
Columbus 14
Santa Clara 14
Chicago 13
Vienna 13
Washington 13
Orem 12
Stockholm 12
Brussels 11
Nanjing 11
Atlanta 10
São Paulo 10
Turku 10
Mexico City 9
Motta di Livenza 9
Boston 8
Chennai 8
Johannesburg 8
Brooklyn 7
Denver 7
Montreal 7
Nuremberg 7
Falkenstein 6
Frankfurt am Main 6
Guangzhou 6
London 6
Palermo 6
Poplar 6
San Francisco 6
Toronto 6
Ankara 5
Bari 5
Bolzaneto 5
Brasília 5
Curitiba 5
Dhaka 5
Düsseldorf 5
Phoenix 5
Pune 5
Quito 5
Seoul 5
Woodbridge 5
Changsha 4
Chongqing 4
Dubai 4
Houston 4
New Delhi 4
Rio de Janeiro 4
Amman 3
Amsterdam 3
Ann Arbor 3
Belo Horizonte 3
Biên Hòa 3
Buenos Aires 3
Cairo 3
Dakar 3
Elk Grove Village 3
Haiphong 3
Hortolândia 3
Kyiv 3
Manaus 3
Manchester 3
Norwalk 3
Ottawa 3
Padua 3
Qingdao 3
Rome 3
Salvador 3
Shijiazhuang 3
São Vicente 3
Tashkent 3
Torino 3
Totale 2.705
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Nome #
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients? 101
COMPOSTI AD ATTIVITÀ ANTIPARASSITARIA 95
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea 94
Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells 90
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization 88
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 80
Identification of a Potent and Selective 5-HT1AReceptor Agonist with in Vitro and in Vivo Antinociceptive Activity 79
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization 79
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration 78
EFFECTS OF ENDOCRINE ACTIVE CONTAMINATING PESTICIDES ON RACK1 EXPRESSION AND IMMUNOLOGICAL CONSEQUENCES IN THP-1 CELLS 78
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies 77
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 74
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases 73
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 68
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain 66
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R) 66
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 64
Investigation of the effect of different linker chemotypes on the inhibition of Histone Deacetylases (HDACs) 64
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents 63
An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases 62
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers 62
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 62
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities 62
Cannabinoid profiling of hemp seed oil by liquid chromatography coupled to high-resolution mass spectrometry 61
Neurodegeneration: can metabolites from Eremurus persicus help? 60
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 60
A multidisciplinary approach to the design of novel inhibitors for KPC-2 59
Chemical and spectroscopic characterization data of ‘cannabidibutol’, a novel cannabidiol butyl analog 59
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells 58
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain 58
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections 58
Analysis of impurities of cannabidiol from hemp. Isolation, characterization and synthesis of cannabidibutol, the novel cannabidiol butyl analog 57
Druggability profile of stilbene-derived PPAR agonists: Determination of physicochemical properties and PAMPA study 57
Sigma-1 receptor agonists acting on aquaporin-mediated h2o2 permeability: New tools for counteracting oxidative stress 57
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates 56
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview 56
The novel heptyl phorolic acid cannabinoids content in different Cannabis sativa L. accessions 56
Development of therapeutic agents blocking SOS activation 54
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid? 53
A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol 53
Evolving Challenges and Opportunities in Plant-based Drug Discovery and Development 50
Evidence of pyrimethamine and cycloguanil analogues as dual inhibitors of trypanosoma brucei pteridine reductase and dihydrofolate reductase 48
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era 47
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 47
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 46
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents 45
Is cannabidiol a scheduled controlled substance? Origin makes the difference 45
Ten Years with New Delhi Metallo-β-lactamase-1 (NDM-1): From Structural Insights to Inhibitor Design 45
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer 45
Origin of Δ9-Tetrahydrocannabinol Impurity in Synthetic Cannabidiol 44
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics 43
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor 43
New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation 43
New weapons against antimicrobial resistance: 
Targeting SOS response to recover b
 actericidal activity of antibiotics
 42
Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol 41
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization 39
Effect of stilbene and chalcone scaffolds incorporation in clofibric acid on PPARα agonistic activity 39
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation 39
Identification of a novel extracellular inhibitor of FGF2/FGFR signaling axis by combined virtual screening and NMR spectroscopy approach 38
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR–Small Molecule Complexes 36
Geometric Isomerism of an Acetamidino Derivative Determined by NMR Investigations 35
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 35
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa 32
Discovery of semisynthetic derivatives of (R)- and (S)-usnic acids as potential antifungal agents against C. tropicalis and T. rubrum 31
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase 30
Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins 30
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 29
Urea-based anticancer agents. Exploring 100-years of research with an eye to the future 29
Phenyl boronic acids development led to validated leads active in clinical strains overexpressing KPC-2: a step against bacterial resistance 29
Structural development studies of PPARs ligands based on tyrosine scaffold 27
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol 26
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 26
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To InhibitTrypanosoma bruceiPteridine Reductase in Support of Early-Stage Drug Discovery 26
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds 26
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 25
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs 25
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 24
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents 24
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 23
In Silico-Guided Discovery and In Vitro Evaluation of Natural Sortase A Inhibitors to Fight Multidrug-Resistant Staphylococcus aureus 22
Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections 20
In silico identification and experimental validation of hits active against KPC-2 β-lactamase 20
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group 18
Phenylboronic Acids Probing Molecular Recognition against Class A and Class C beta-Lactamases 18
Optimization of N-alkylation in the Synthesis of Methotrexate and Pteridine-based Derivatives Under Microwave-Irradiation 17
Use of primary amines for the selective N-Alkylation of anilines by a reusable heterogeneous catalyst 16
Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach 9
Totale 4.234
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Categoria #
all - tutte 24.203
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.203
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202112 0 0 0 0 0 0 4 4 4 0 0 0
2021/2022120 0 0 16 0 1 3 1 13 2 4 22 58
2022/2023729 33 45 14 65 56 76 0 47 341 9 27 16
2023/2024502 23 92 21 27 34 124 63 40 6 21 22 29
2024/20251.262 22 92 20 24 33 118 84 60 310 60 142 297
2025/20261.589 238 247 337 305 363 99 0 0 0 0 0 0
Totale 4.234